Clinical trials: Depression and Anxiety Symptom
Crohn Disease, Ulcerative Colitis (UC)
Use of Psychologist-administered Cognitive Behavioral Therapy (CBT) or Self-administered CBT for the Treatment of Anxiety and/or Depression in Inflammatory Bowel Disease (IBD)
This is a prospective, single center, randomized treatment study to assess if anxiety and depression in participants with IBD can be improved with CBT compared to those treated with SKY.
- Trial name
- NCT05377840
- Testing
- Psychologist-administered Cognitive Behavioral Therapy, Self-Administered Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Yale University
Surgery
Green Light for Post-Operative Wellness
This is an unblinded, parallel group randomized controlled trial to evaluate bright green light as an adjunct therapy after surgery at UPMC Shadyside.
- Trial name
- GLOW (NCT07218289)
- Testing
- Bright Green Light Therapy, Dim White Light Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Rebecca E Kotcher, MD
Psychological Distress, Depression
Peer Intervention to Improve Access Among Rural Women Veterans With Psychological Distress and Unmet Social Needs
This research project will refine and evaluate delivery of a peer-delivered evidence-based intervention to improve perceived access and actual engagement with mental health treatment and social resource service use among rural…
- Conditions
- Psychological Distress, Depression, PTSD, Anxiety
- Trial name
- EMBER (NCT05477706)
- Testing
- Personalized Support for Progress (PSP), Tailored Referral (TR)
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- Syracuse VA Medical Center
Anxiety, Depression
Improving Adherence to Homework During Therapy
The purpose of this study is to expand Adhere.ly- a simple, HIPAA-compliant, web-based platform to help therapists engage clients in practicing therapeutic skills between sessions (homework) during mental health treatment by…
- Conditions
- Anxiety, Depression, Depression/Anxiety
- Trial name
- Adherely STTR (NCT05866185)
- Testing
- Therapy, Therapy + Adhere.ly
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- University of South Florida
PTSD, Depression
Effectiveness of Combined Intervention Approaches in the Treatment of Affective Disorders and Chronic Pain in War Victims
This study will measure the effects of biofeedback supported cognitive behavioral therapy (BF-CBT) and group physiotherapy intervention in victims of torture and massive violence in Kosovo.
- Conditions
- PTSD, Depression, Anxiety, Chronic Pain
- Trial name
- NCT01696578
- Testing
- BF-CBT and group physiotherapy
- Where
- Kosovo
- Volunteers
- 31 people
- Sponsor
- Rehabilitation and Research Centre for Torture Victims
Cohort Studies
Effect of Dexmedetomidine on Postoperative Mental Disorders and Long-term Survival in Elderly Patients
China's aging population is causing an increase in the number of senior persons undergoing surgery. More and more clinicians are paying attention to the postoperative survival and mental health of elderly surgical patients.
- Trial name
- NCT06362408
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Chinese PLA General Hospital
Depressive Disorder and Anxiety Disorders
To Investigate Effects GSK561679 on Part of the Body's System That Controls the Balance of Many of the Hormones.
A study to investigate the effects GSK561679 on part of the body's system that controls the balance of many of the hormones (including cortisol).
- Trial name
- NCT00426608
- Testing
- metyrapone, alprazolam, GSK561679
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Anxiety, Depression
An Online Intervention Addressing Mental Health and Substance Use in University Students
The purpose of this study is to assess the effectiveness of mobile app containing a range of evidence based tools to improve the mental health and substance use outcomes of university students.
- Conditions
- Anxiety, Depression, Alcohol Use, Substance Use
- Trial name
- NCT05606601
- Testing
- Minder
- Where
- Canada
- Volunteers
- 1,489 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Post Traumatic Stress Disorder, Depression
CARE Study for Paramedics in Singapore
The purpose of this study is to compare the effectiveness of two different online education courses (Oxford-Online and Mind-Online) for preventing stress related conditions among paramedics who have been working during a period…
- Conditions
- Post Traumatic Stress Disorder, Depression, Anxiety Disorders and Symptoms, Burnout
- Trial name
- NCT07457801
- Testing
- Oxford-Online, Mind-Online
- Where
- Singapore
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Caregiver Burden, Self Efficacy
An Online Ecoaching RCT Intervention for Carers: Enhancing Wellbeing and Resilience Through Self-Help Strategies
The goal of this three-armed, double-blind randomized controlled trial (RCT) is to compare the effectiveness of an online self-help eCoaching intervention designed for caregivers.
- Conditions
- Caregiver Burden, Self Efficacy, Quality of Life, Anxiety Depression
- Trial name
- NCT06604481
- Testing
- eCoaching for Caregivers of Older Adults, eCoaching (need specific) for Caregivers of Older Adults, Control Intervention for Caregivers of Older Adults
- Where
- Hong Kong
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Chronic Pain, Post Intensive Care Unit Syndrome
The Post-ICU Pain Study
BACKGROUND: ICU survivors may experience serious psychological, physical and cognitive impairments following ICU admission, collectively termed Post Intensive Care Syndrome (PICS).
- Conditions
- Chronic Pain, Post Intensive Care Unit Syndrome, Quality of Life, Pain Disorder
- Trial name
- PIP (NCT07180407)
- Where
- 4 sites in Denmark
- Volunteers
- 800 people
- Sponsor
- Zealand University Hospital
Idiopathic Pulmonary Fibrosis, Depression
Palliative Care and Quality of Life in Idiopathic Pulmonary Fibrosis
The purpose of this study is to evaluate the effects of adding a palliative care intervention for patients with idiopathic pulmonary fibrosis (IPF) to current standard of care.
- Conditions
- Idiopathic Pulmonary Fibrosis, Depression, Anxiety, Depressive Disorder
- Trial name
- NCT03981406
- Testing
- Palliative Care, Standard of Care
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Minnesota
Anxiety Symptoms, Post-traumatic Stress Symptoms
Improving Student Mental Health Through a Universal Trauma-Informed Intervention
The goal of this trial is to identify the most effective ways for schools to deliver RAP Club, a universal school-based mental health intervention.
- Conditions
- Anxiety Symptoms, Post-traumatic Stress Symptoms, Depressive Symptoms, Behavioral Problems
- Trial name
- PPP (NCT07842432)
- Testing
- RAP Club Delivered by a School Clinician, RAP Club Delivered by a Teacher, Standard Supervision
- Where
- 3 sites in United States
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Infertility, Female, Anxiety
Multifaceted Benefits of Auricular Point Sticking for IVF Patients: Psychological Well-being, Sleep, and Treatment Outcomes
The goal of this clinical trial is to evaluate whether the complementary intervention of auricular point sticking therapy (APST) can improve pregnancy outcomes by ameliorating psychological distress and sleep quality in female…
- Conditions
- Infertility, Female, Anxiety, Assisted Reproductive Techniques, Dyssomnias
- Trial name
- NCT07409792
- Testing
- auricular point sticking therapy, Conventional Artificial Cycle Therapy
- Where
- China
- Volunteers
- 178 people
- Sponsor
- Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University
Anxiety, Depression
Community Applications of the MindShift App
Despite considerable, replicated evidence of the efficacy and effectiveness of cognitive behavioural therapy, there is an insufficient number of professionals (e.g., psychologists, psychiatrists) in North America to provide…
- Conditions
- Anxiety, Depression, Anxiety Generalized, Anxiety Disorders and Symptoms
- Trial name
- NCT04562948
- Where
- Canada
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- University of Windsor
Acquired Brain Injury, Mental Health
Occupational Therapy for Mental Health and Engagement in Neurorehabilitation
Changes in mental health are common after acquired brain injury (ABI), defined as any traumatic or non-traumatic injury to the brain after birth, affecting approximately 1 in 3 adults with ABI.
- Conditions
- Acquired Brain Injury, Mental Health, Depressive Symptoms, Anxiety Symptoms
- Trial name
- OT for ME (NCT07375485)
- Testing
- Multifaceted implementation program
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Depression, Anxiety
Sea Swimming for Treatment of Depression and Anxiety
There is a developing evidence to suggest that open cold water swimming could have an impact on depression and anxiety: anecdotal reports of benefits to mental wellbeing as a result of regular open water bathing research…
- Trial name
- NCT04528485
- Testing
- Sea swimming
- Where
- United Kingdom
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Devon Partnership NHS Trust
Insomnia, Depression
Adjunctive Brief Behavioral Treatment of Insomnia (BBTI) for Sleep Intervention (SI)
There is a strong association between sleep disturbance and suicidal thoughts and behaviors. Sleep disturbance is also highly comorbid with other common conditions associated with suicide such as depression and posttraumatic…
- Conditions
- Insomnia, Depression, Posttraumatic Stress Disorder, Suicidal Ideation
- Trial name
- NCT02248675
- Testing
- CBT-I, TAU
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- VA Office of Research and Development
Depression, Clinical Depression
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Depression
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records
- Conditions
- Depression, Clinical Depression, Depression, Anxiety, Depression, Postpartum
- Trial name
- NCT04211467
- Testing
- No Intervention
- Where
- United States
- Sponsor
- ProgenaBiome
Pregnancy, Post Partum
Deconstructing Maternal Burdens: Doulas and the Community Unite for Health
This study is a randomized controlled trial comparing two models of doula support for pregnant individuals enrolled in Medicaid: an enhanced doula support model, in which support starts earlier in pregnancy, occurs more…
- Conditions
- Pregnancy, Post Partum, Doula Care, Postpartum Depression (PPD)
- Trial name
- UNITE (NCT07799805)
- Testing
- Doula, Standard (non-enhanced) Medicaid doula support
- Where
- United States
- Volunteers
- 516 people
- Sponsor
- University of Florida