Clinical trials: Depression and Quality of Life
General Mental Health and Well-Being, Mental Disorders
PREWELL Digital Well-being Promotion Intervention With the BitHabit App
Mental wellbeing is a major public health concern, and digital interventions have emerged as a scalable approach for promoting mental well-being and healthy lifestyle behaviors.
- Conditions
- General Mental Health and Well-Being, Mental Disorders, Common Mental Disorders (CMD)
- Trial name
- PREWELL (NCT07868146)
- Testing
- Digital wellbeing promoting intervention with the BitHabit app
- Where
- Finland
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Temporomandibular Disorder (TMD)
Marine Lipids Ease Painful TMD
The ADAPT study is a single-site, Phase 2b, randomized, quadruple-masked, placebo-controlled trial evaluating an omega-3 dietary supplement enriched with specialized pro-resolving mediator (SPM) precursors in adults with chronic…
- Trial name
- ADAPT (NCT07437313)
- Testing
- SPM Precursor-Enriched Marine Lipid Supplement, Medium-Chain Triglyceride Supplement
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
Dementia, Mild, Mild Cognitive Impairment
CAPABLE Family Pilot - Adapting CAPABLE for Older Adults With Mild Cognitive Impairment (MCI)/Early Stage Dementia and Their Care Partners
The purpose of this study is to test the adapted protocol, CAPABLE Family which builds upon the evidenced based CAPABLE program to address older adults with co-occurring physical disability and mild cognitive impairment or early…
- Conditions
- Dementia, Mild, Mild Cognitive Impairment, Disability Physical, Impairment, Cognitive
- Trial name
- NCT05187117
- Testing
- CAPABLE Family - Open Label Pilot, CAPABLE Family - Randomized Control Trial
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Multiple Sclerosis, Relapsing-remitting
A Observational, Prospective Study to Assess the Impact of Fatigue in the Quality of Life of Patients With Multiple Sclerosis in Argentina
This is an observational, non-controlled, multicentric, prospective study planned to be conducted in 66 subjects diagnosed with multiple sclerosis (MS) in 20 centres of Argentina.
- Trial name
- NCT01080001
- Where
- Argentina
- Volunteers
- 71 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Depression
Family Focused Nursing for Elderly Medical Patients
The purpose of this study is to determine whether Family Focused Nursing are effective in the treatment of elderly medical patients with respect to prevalence of depression
- Trial name
- NCT02408081
- Testing
- Family Focused Nursing
- Where
- Denmark
- Sponsor
- University of Southern Denmark
Dementia, Malnutrition
Patient Participation in Prevention of Loss of Functions
Randomized Clinical Trial (RCT) To investigate and compare the effect of two preventive interventions on readmission rates, loss of functions, quality of life and cost-benefit.
- Conditions
- Dementia, Malnutrition, Depression, Pain
- Trial name
- NCT01843907
- Testing
- Empowerment, Conversation with nurse
- Where
- Denmark
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Arthrogryposis, Craniofacial Abnormalities
Study of Quality of Life in Freeman-Sheldon Syndrome and Related Conditions
Freeman-Sheldon syndrome (FSS) is a rare human neuromusculoskeletal disorder present before birth, involving primarily limb and craniofacial deformities.
- Conditions
- Arthrogryposis, Craniofacial Abnormalities, Posttraumatic Stress Disorder, Depressive Disorder
- Trial name
- FSS-QLS (NCT01307475)
- Testing
- PTSD Checklist-Specific, Modified Flanagan Quality of Life Scale, Center for Epidemiologic Studies Depression Scale
- Where
- 2 sites in United States, Guatemala
- Volunteers
- 6 people
- Sponsor
- Freeman-Sheldon Research Group, Inc.
Mental Health Care, Depression Anxiety Disorder
Effectiveness of Exercise, Walking, and Education on Mental Health, Mobility and Quality of Life in Elderly Residents of Nursing Homes
Clinical Trial This clinical trial aims to determine the impact of physiotherapy interventions on mental health, quality of life, and spinal mobility in older adults.
- Conditions
- Mental Health Care, Depression Anxiety Disorder, Quality of Life
- Trial name
- NCT07236424
- Testing
- Physiotherapy
- Where
- Bosnia and Herzegovina
- Volunteers
- 44 people
- Sponsor
- University of Mostar
Major Depressive Disorder, Insomnia
Quetiapine Extended Release (XR) for the Treatment of Menopausal Depression
The study was designed to examine the efficacy and tolerability of quetiapine XR for the treatment of women who suffer from depression in the context of the menopausal transition and postmenopausal years.
- Conditions
- Major Depressive Disorder, Insomnia, Hot Flashes
- Trial name
- NCT00723970
- Testing
- Quetiapine Extended Release
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- McMaster University
Feasibility Studies, Physical Activity
AI-Based Personalized Exercise Prescription Through Mobile Health on Physical Activity and Health Outcomes in Older Adults: A Feasibility Study
The purpose of this research is to investigate the feasibility, acceptability, appropriateness, and preliminary efficacy of a wearable and artificial intelligence-driven mobile application-based exercise prescription grounded in…
- Conditions
- Feasibility Studies, Physical Activity, Mental Health (Depression), Anxiety
- Trial name
- NCT07768670
- Testing
- Fitness app powered by AI and wearable device
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Depression, Stage I Breast Cancer
Factors Affecting Weight Gain in Women Receiving Adjuvant Chemotherapy for Breast Cancer
RATIONALE: Chemotherapy may affect various factors that can lead to weight gain. PURPOSE: Clinical trial to evaluate factors that may affect weight gain in women receiving adjuvant chemotherapy for stage I, stage II, or stage…
- Conditions
- Depression, Stage I Breast Cancer, Stage IIIA Breast Cancer, Nutrition
- Trial name
- NCT00019643
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Idiopathic Pulmonary Fibrosis, Dyspnoea
Modelling of Quality Life, Clinical and Physiological Measures in Idiopathic Pulmonary Fibrosis
As there are no validated tools for assessing patient reported outcomes or health related quality of life in idiopathic pulmonary fibrosis (IPF), different studies have utilised different methods.
- Conditions
- Idiopathic Pulmonary Fibrosis, Dyspnoea, Anxiety, Depression
- Trial name
- NCT02176707
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- University of East Anglia
Sleep Apnea, Obstructive
Telecommunications System in Sleep Apnea
This study is investigating the effects of a telecommunications system designed to improve patient adherence with prescribed positive airway pressure (CPAP).
- Trial name
- NCT00232544
- Testing
- Telecommunications system, TLC-Control
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- VA Office of Research and Development
Cognitive Decline, Osteoarthritis
Healthy Body & Mind Program for Older Adults Living With Osteoarthritis and Cognitive Decline
The goal of this pilot randomised clinical trial is to compare a 12-week Healthy Body \& Mind Program to usual care in older adults living with cognitive decline and osteoarthritis.
- Trial name
- NCT06070818
- Testing
- Healthy Body & Mind Program
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- The University of New South Wales
Anxiety Disorders, Depressive Disorders
Role of the Stress in the Development of the Metabolic Syndrome
The purpose of this study is determine the incidence of metabolic syndrome (MetS) in people of high risk, of 40 or more years and attended in the Primary Care.
- Conditions
- Anxiety Disorders, Depressive Disorders, Metabolic Syndrome, Stress Disorders
- Trial name
- STREX (NCT01538082)
- Where
- Spain
- Volunteers
- 738 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Caregiver Subjective Burden, Depressive Symptoms
Effectiveness of an Online Training and Support Program (iSupport) for Informal Dementia Caregivers
Informal caregivers of people with dementia are at greater risk of developing physical and mental health problems when compared to the general population and to informal caregivers of people with other chronic diseases.
- Conditions
- Caregiver Subjective Burden, Depressive Symptoms, Anxiety Symptoms
- Trial name
- iSupportPT (NCT04104568)
- Testing
- iSupport for dementia - European-Portuguese version, e-book (comparator)
- Where
- Portugal
- Volunteers
- 184 people
- Sponsor
- Universidade do Porto
Breasts - Female, Breast Cancer
Effects of a Pilates Studio Program on Quality of Life and Functional Capacity of Women Undergoing Breast Cancer Treatment
Introduction: Cancer treatment generates undesirable effects, directly affecting the functional and psychosocial capacity faced by breast cancer patients during treatment.
- Conditions
- Breasts - Female, Breast Cancer, Breast Cancer in Women
- Trial name
- Cancer (NCT07599098)
- Testing
- Pilates Studio Program Group
- Volunteers
- 50 people
- Sponsor
- Federal University of Maranhao
Carcinoma, Non-Small-Cell Lung, Cancer of the Gastrointestinal Tract
Effect of Qigong Therapy in Patients With Advanced Lung and Gastrointestinal Cancer Undergoing Chemotherapy
Cancer patients face a number of symptoms related to treatment or disease which may impair quality of life, such as decreased functional capacity, fatigue, nausea an vomiting, distress, depression and unmet psychological needs.
- Trial name
- NCT01374100
- Testing
- Standard Exercise, Qigong Exercise
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- McGill University
Anxiety, Depression
Quality of Life and Device Acceptance in Patients With ICD Undergoing Remote ICD FU
This study investigates whether an additional remote follow-up of patients with implantable cardioverter-defibrillators (ICDs) has beneficial effects on Quality of life (QoL), levels of anxiety and depression and device…
- Trial name
- NCT02888028
- Testing
- ICD remote monitoring, Control group
- Where
- 2 sites in Germany
- Volunteers
- 182 people
- Sponsor
- LMU Klinikum
Lung Cancer
Maximal Exercise Capacity and Extra-pulmonary Characteristics in Patients With Lung Cancer With Complete Remission .
While lung cancer are rare disease in the early 20th century, its incidence increased in parallel with the increase in smoking habits. It is the most common type of cancer in the world.
- Trial name
- NCT03838757
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gazi University