Clinical trials: Depression and Quality of Life
Mental Health Impairment, Stress, Psychological
Health and Quality of Life Among Resettled Syrians in Norway
Brief summary The civil war in Syria has taken a severe toll on the Syrian population, with over 350 000 dead and more than 10 million Syrians forced to leave their home since 2011.
- Conditions
- Mental Health Impairment, Stress, Psychological, Quality of Life, Health, Subjective
- Trial name
- REFUGE-I (NCT03742128)
- Where
- Norway
- Volunteers
- 3,000 people
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Chronic Low Back Pain (CLBP)
Chronic Low Back Pain: TOTALSPINE - UO04
Background: Low back pain (LBP) is the primary factor contributing to years lived with disability. In view of the close correlation between the functions of the body, which cannot be examined piecemeal but as an integrated…
- Trial name
- TOTALSPINE (NCT06895317)
- Testing
- Remote rehabilitation, Rehabilitation face to face
- Where
- 2 sites in Italy
- Volunteers
- 86 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Anxiety, Depression
Managing Anxiety From Cancer (MAC): Testing an Intervention for Anxiety in Older Adults With Cancer and Their Caregivers
This study is being done to test the effects of Managing Anxiety from Cancer (MAC) therapy on anxiety compared to usual care, in patients and their caregivers.
- Conditions
- Anxiety, Depression, Quality of Life
- Trial name
- NCT03168971
- Testing
- Managing Anxiety from Cancer (MAC)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Depression
Exercise and Severe Depression: Clinical and Biological Analysis
The study aimed to evaluate the use of exercise as a complementary strategy to treat severe major depression in inpatients. Hypothesis: Exercise can be used as a safe and efficacious complimentary strategy in severe depressed…
- Trial name
- NCT01899716
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Pain Management, Thoracic Trauma
Comprehensive Multicenter Study on the Management of Acute Pain Following Thoracic Combat-Related Trauma in Ukraine
This study is a multicenter clinical trial conducted in Vinnytsia, Rivne, and Lviv, Ukraine, focusing on the management of acute pain following thoracic injuries sustained during combat.
- Conditions
- Pain Management, Thoracic Trauma, Pulmonary Function, Quality of Life
- Trial name
- CMS-APT-UA (NCT07380789)
- Testing
- Cryoablation, Radiofrequency ablation alone
- Where
- Ukraine
- Volunteers
- 50 people
- Sponsor
- Lviv National Medical University
Anxiety Disorder, Depression
Combination Chemotherapy Plus Fluoxetine in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer
This trial is designed to test the efficacy of fluoxetine to improve patient's quality of life during chemotherapy. An innovative application of a selective serotonin reuptake inhibitor may modulate the effects of fatigue…
- Conditions
- Anxiety Disorder, Depression, Fatigue, Lung Cancer
- Trial name
- NCT00005850
- Testing
- cisplatin, fluoxetine, gemcitabine hydrochloride
- Where
- 43 sites in United States, Puerto Rico
- Volunteers
- 21 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Depression, Loneliness
Use of a Voice Assistant to Improve Mental Health in Older People
The main objective of this study is to evaluate the effectiveness of DIAL (an innovative and user-friendly solution based on Multiplatform Voice Assistive Technologies) in reducing unwanted loneliness and increasing the mental…
- Conditions
- Depression, Loneliness, Anxiety, Quality of Life
- Trial name
- NCT06070402
- Testing
- DIAL, a voice-controlled virtual assistant
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Depression and Quality of Life
ICBT for Mental Health Problems Related to the Climate Crisis
The study seeks to investigate the effects of a guided internet-based cognitive behavioral therapy (ICBT) programme on adult mental health problems related to the climate crisis.
- Trial name
- NCT05169736
- Testing
- Cognitive Behavioural Therapy
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Linkoeping University
Liver Cancer, Anxiety Disorder
Early Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family Caregivers
The study intervention consists of the early integration of palliative care services into standard oncology care in an outpatient setting for patients with advanced lung and non-colorectal gastrointestinal malignancies who are…
- Conditions
- Liver Cancer, Anxiety Disorder, Depression, Small Cell Lung Cancer
- Trial name
- NCT02349412
- Testing
- Early palliative care
- Where
- 23 sites in United States
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- Alliance for Clinical Trials in Oncology
Irritable Bowel Syndrome
The Effect of Laughter Yoga on Symptom Severity, Depression-anxiety-stress, Sleep Quality and Quality of Life in Patients with Irritable Bowel Syndrome
The study will be conducted to evaluate the effect of laughter yoga on symptom severity, depression, anxiety, stress, sleep and quality of life in patients with Irritable Bowel Syndrome (IBS).
- Trial name
- NCT06705153
- Testing
- laughter yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Ataturk University
Hypogonadism
Psychological Outcomes in Isolated GnRH Deficiency
Background: Isolated (or Congenital) GnRH Deficiency (IGD) is a rare disease. People who have this go through puberty late. Some never reach puberty or don t complete it without treatment.
- Trial name
- NCT02356172
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Bipolar Depression
Efficacy of Quetiapine XR Versus Divalproex on Clinical Outcome Quality of Sleep and Quality of Life in Bipolar Depression
Quetiapine is one of atypical antipsychotics with good efficacy and better side effect profiles than conventional antipsychotics, so it is being widely used beyond the treatment of schizophrenia.
- Trial name
- NCT01587066
- Testing
- Quetiapine fumarate, Divalproex sodium
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bo-Hyun Yoon
Surgery--Complications, Anesthesia Complication
THRIVE Feasibility Trial
To evaluate the feasibility of a pragmatic, large scale, comparative effectiveness, randomized evaluation of patient experience of intravenous propofol versus inhaled volatile anesthesia.
- Conditions
- Surgery--Complications, Anesthesia Complication, Anesthesia Awareness, Anesthesia Emergence Delirium
- Trial name
- THRIVE (NCT05346588)
- Testing
- Anesthetic technique Propofol TIVA, Anesthetic technique inhaled agent
- Where
- 4 sites in United States
- Volunteers
- 300 people
- Sponsor
- Washington University School of Medicine
Depression Chronic, Depression and Quality of Life
Remote Medical Monitoring of Patients With Depression
The goal of this clinical trial is to learn if ThIA Suivi, a digital tool for remote monitoring of patients, can improve the care of adults with depression who are followed by a psychiatrist.
- Conditions
- Depression Chronic, Depression and Quality of Life, Depression, Major Depressive Episode
- Trial name
- TELEMED-DEP (NCT07878754)
- Testing
- Use of ThIA Medical Device
- Where
- 3 sites in France
- Volunteers
- 608 people
- Sponsor
- ThIA Santé Mentale
Palliative Care, Pain
Lysergic Acid Diethylamide (LSD) in Palliative Care
Background: Terminally ill patients often experience significant psychosocial distress having depressed mood, death anxiety, pain, and an overall poor quality of life.
- Conditions
- Palliative Care, Pain, Anxiety, Depression
- Trial name
- LPC (NCT05883540)
- Testing
- Lysergic Acid Diethylamide Tartrate
- Where
- 4 sites in Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Basel, Switzerland
Anxiety, Depression
Effect of Homeopathy, Acupuncture or Anthroposophic Medicine in Women's Quality of Life
Patients will be randomly assigned to two separate groups. Both patient groups will be evaluated using the WHOQOL-BREF questionaire.
- Conditions
- Anxiety, Depression, Premenstrual Tension, Hot Flashes
- Trial name
- NCT02504515
- Testing
- World Health Organization Quality of Life Bref Questionnaire
- Where
- Brazil
- Volunteers
- 906 people
- Sponsor
- Federal University of Minas Gerais
Type 2 Diabetes Mellitus (T2DM), Health-related Quality of Life
Psychological Well-Being, Depression, and Health-Related Quality of Life in Adults With Type 2 Diabetes: A Cross-Sectional Study
This prospective cross-sectional observational study aims to explore the relationships among psychological well-being, depression, and quality of life in patients with type 2 diabetes attending the outpatient metabolic clinic at…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Health-related Quality of Life, Depressive Symptoms, Psychological Well-being
- Trial name
- PWDQ-T2D (NCT07241325)
- Where
- Taiwan
- Volunteers
- 500 people
- Sponsor
- National Taiwan University Hospital
Chronic Obstructive Pulmonary Disease, Exercise
Mind-Body Walking Exercise for Chronic Obstructive Pulmonary Disease
Mind-body exercise improves symptom of negative moods, dyspnea and quality of life in chronic diseases, but these improvements for chronic obstructive pulmonary disease (COPD) are unproven.
- Conditions
- Chronic Obstructive Pulmonary Disease, Exercise, Anxiety, Depression
- Trial name
- NCT03388489
- Testing
- Mind-Body Walking
- Volunteers
- 84 people
- Sponsor
- National Taiwan University Hospital
Post-Intensive Care Syndrome, Anxiety
Family and Patient Outcomes After Pediatric Intensive Care (FOREVER)
This study aims to evaluate in the Brazilian context, the impact of the implementation of a diary program on patient and family-centered outcomes after PICU discharge.
- Conditions
- Post-Intensive Care Syndrome, Anxiety, Depression, Stress Disorders, Post-Traumatic
- Trial name
- FOREVER (NCT04961697)
- Testing
- Hospital diaries
- Where
- Brazil
- Volunteers
- 431 people
- Sponsor
- D'Or Institute for Research and Education
Severe Mobility Impairment, Spinal Cord Injuries (Complete and Incomplete)
The Impact of 'Digital Strolling' on Depression and Quality of Life of People With Severe Mobility Impairment
This intervention aims to develop and test the feasibility, acceptability, and preliminary effects of a "Digital Strolling" intervention among people with SMI.
- Conditions
- Severe Mobility Impairment, Spinal Cord Injuries (Complete and Incomplete), Poliomyelitis
- Trial name
- NCT07073144
- Testing
- Virtual walking, Passive observing walking
- Where
- Hong Kong
- Volunteers
- 24 people
- Sponsor
- The Hong Kong Polytechnic University