Clinical trials: Depression and Quality of Life
Depression
The Preventive Effect of Escitalopram on Depression and Related Emotional Disorders in Acute Stroke Patients
Through this study, the investigators are to demonstrate the superiority of Escitalopram over placebo for the prevention of poststroke depression in patients with acute stroke The primary hypothesis of this study is; This study…
- Trial name
- EMOTION (NCT01278498)
- Testing
- Escitalopram, sugar pill
- Where
- 16 sites in South Korea
- Volunteers
- 444 people
- Sponsor
- Asan Medical Center
COVID-19 Pandemic
Investigation of Physical and Emotional Status the Elderly Infected and Non-Infected With COVID-19
The aim of this observational study is to evaluate individuals in terms of balance, functional mobility, influences in activities of daily living, fear of COVID-19, moods, quality of life parameters in order to investigate the…
- Trial name
- NCT05905211
- Testing
- Observational Tests
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Intervention Compliance, Usability
CSDM: A Trial to Improve Communication and Shared Decision Making Using a Web-Based Tool
The goal is to develop a pragmatic, scalable intervention to overcome problems with surrogate decision making in ICUs. The aim is to conduct a pilot study among surrogates and clinicians of 50 incapacitated patients at high risk…
- Conditions
- Intervention Compliance, Usability, Acceptability
- Trial name
- CSDM Pilot (NCT02955563)
- Testing
- CSDM Web-Based Tool Intervention
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Diabetes Mellitus, Diabetes Mellitus ( Type 1 and Type 2)
Mindfulness-Based Cognitive Behavioral Program for People With Diabetes Mellitus
This randomized controlled trial evaluated the effectiveness of a mindfulness-based cognitive behavioral program in improving quality of life and glycemic control among adults with diabetes mellitus in Damascus, Syria.
- Conditions
- Diabetes Mellitus, Diabetes Mellitus ( Type 1 and Type 2), Depressive Symptoms
- Trial name
- NCT07779044
- Testing
- Mindfulness-Based Cognitive Behavioral Program
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Center for Strategic Studies and Health Training, Syria
Atopic Dermatitis
A Study to Evaluate the Quality of Life of Male and Female Adult Patients With Severe Refractory Atopic Dermatitis Treated With Dupilumab in Czech Republic
Assessment of the relationship between treatment response (EASI75) and change in quality of life (EQ-5D) by week 24. Description of the: Change in disease activity after 16 and 24 weeks Change in subject and family quality of…
- Trial name
- NCT05527964
- Where
- Czechia
- Volunteers
- 146 people
- Sponsor
- Sanofi
Major Depressive Disorder (MDD)
Group Acceptance and Commitment Therapy (ACT) Among Depressive Patients in Kelantan, Malaysia
The goal of this clinical trial is to learn if group acceptance and commitment therapy works to improve depressive symptoms, psychological flexibility and quality of life in adults. The main questions it aims to answer are: 1.
- Trial name
- Group ACT (NCT06710912)
- Testing
- Group acceptance and commitment therapy (ACT), Treatment as usual
- Where
- Malaysia
- Volunteers
- 44 people
- Sponsor
- Universiti Sains Malaysia
Epilepsy, Anxiety
Collaborative Care for Anxiety and Depression in Epilepsy
This is a randomized effectiveness/implementation trial comparing a 24-week neurology-based collaborative care intervention to usual neurology care among 60 adults with epilepsy.
- Conditions
- Epilepsy, Anxiety, Depression
- Trial name
- NCT05559749
- Testing
- collaborative care, usual neurology care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Wake Forest University Health Sciences
GVHD, Chronic, GVHD - Graft-Versus-Host Disease
Psychiatric Status and Symptom Severity in Graft-versus-Host Disease (GvHD).
This prospective observational study evaluates the association between psychiatric status, GvHD-related symptom severity, and health-related quality of life in patients with graft-versus-host disease.
- Conditions
- GVHD, Chronic, GVHD - Graft-Versus-Host Disease, GVHD, Quality of Life
- Trial name
- Psych-GvHD (NCT07314892)
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Gdansk
Agitation, Anxiety
Learning Oriented Physiotherapy - a New Approach
Outpatients that suffer from different anxiety disorders may have physical ailments that negatively affect daily life functioning and quality of life.
- Conditions
- Agitation, Anxiety, Dizziness, Pain
- Trial name
- LOF (NCT02194036)
- Testing
- Learning Oriented Physiotherapy, Widely Recognized Psychiatric Treatment
- Where
- 3 sites in Norway
- Volunteers
- 81 people
- Sponsor
- Helse Nord-Trøndelag HF
Musculoskeletal Pain, Fatigue
Parameters of the General Health Status of Prison Officers
Introduction The working conditions of prison officers are very stressful. Today, it is known that stress affects the health status of individuals in many ways.
- Conditions
- Musculoskeletal Pain, Fatigue, Depression, Quality of Life
- Trial name
- NCT06313099
- Testing
- Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 141 people
- Sponsor
- Pakize Nurgul Sen
Depression
Exercise and Severe Depression: Clinical and Biological Analysis
The study aimed to evaluate the use of exercise as a complementary strategy to treat severe major depression in inpatients. Hypothesis: Exercise can be used as a safe and efficacious complimentary strategy in severe depressed…
- Trial name
- NCT01899716
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Chronic Pancreatitis, Depression
Determinants of Depression and Its Impact on Quality of Life in Patients With Chronic Pancreatitis
Chronic pancreatitis (CP) is associated with recurrent intractable abdominal pain, pancreatic exocrine insufficiency and endocrine dysfunction.
- Conditions
- Chronic Pancreatitis, Depression, Quality of Life, Chronic Pain
- Trial name
- NCT04867304
- Testing
- Patient education about chronic pancreatitis.
- Where
- India
- Volunteers
- 625 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Congenital Heart Disease
Impact of a Cardiac and Mental Health Rehab Program on Well-Being and Fitness in Young Adults With Fontan Circulation: A Randomized Trial
Helping Young Adults With Fontan Circulation Feel Better and Stay Active What is the study about? This study looked at how a special program could help young adults with Fontan circulation feel better mentally and physically.
- Trial name
- (NCTXXXXXXXX) (NCT06844149)
- Testing
- CPR; (Cardiac and Psychosocial Rehabilitation) with Cardiac Rehabilitation, CR; Home-Based Cardiac Rehabilitation, Usual Care
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Samsung Medical Center
Spina Bifida, Self Esteem
Psychosocial Teleassistance Programme for Adults With Spina Bifida
This clinical trial assesses the effect of a telecare psychosocial intervention designed for adults with spina bifida. The intervention consists of 10 weekly 1.5-hour group sessions, followed by two 3-month follow-up sessions.
- Conditions
- Spina Bifida, Self Esteem, Quality of Life (QOL), Self Concept
- Trial name
- NCT07178873
- Testing
- Psychosocial teleassistance intervention
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- University of Deusto
Patients With Major Depressive Disorder
Cognitive Behavior Therapy Among Patients With Major Depressive Disorder-Multiple Episodes.
The main purpose of this study to teach the patients how to manage their depression, generalized Anxiety symptoms, mental health seeking attitude, motivation and attitude toward changing health, to improve the quality of life…
- Trial name
- NCT07300527
- Testing
- Cognitive Behavior Therapy, treatment as usual (TAU) (Control Group)
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Fibromyalgia Syndrome, Fibromyalgia
Effects of 2-Aticyto Complex and D-Ribose on Pain and Clinical Course in Patients With Fibromyalgia
This multicenter, randomized, double-blind, placebo-controlled study will evaluate whether an oral supplement containing 2-Aticyto Complex and D-ribose (FibroThol), added to ongoing standard medical treatment, improves pain…
- Trial name
- NCT07495943
- Testing
- 2-Aticyto Complex and D-ribose Oral Supplement
- Where
- 5 sites in Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Myasthenia Gravis
Cognitive Functioning in People With Myasthenia Graivs: Impact on Daily Life Activities, Work, Disability and Quality of Life
MYCOG primarily aims to estimate the prevalence of cognitive difficulties in patients with MG treated at Besta Institute. Secondary aims include: a) assess the degree to which cognitive difficulties are associated to work…
- Trial name
- MYCOG (NCT06718855)
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Insulin Resistance, Depression
Health Related QOL, Depression and Lifestyle Changes in Insulin Resistant Adolescents
The purpose of this study is to assess adolescents with Insulin Resistance Syndrome for quality of life and altered health related issues.
- Trial name
- NCT00493259
- Testing
- Health-Related Quality of Life instrument, Depression Scale for Children (CES-DC)
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Children's Mercy Hospital Kansas City
Covid19, Chronic Kidney Diseases
Physical Activity Level in Patients with Chronic Kidney Disease During COVID-19 Pandemic
In the literature, there are no studies evaluating fear of COVID-19, anxiety, depression, physical activity, fear of movement and quality of life in patients with chronic kidney disease during COVID-19 pandemic.
- Trial name
- NCT04745923
- Where
- Turkey (Türkiye)
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Major Depressive Disorder, Insomnia
Quetiapine Extended Release (XR) for the Treatment of Menopausal Depression
The study was designed to examine the efficacy and tolerability of quetiapine XR for the treatment of women who suffer from depression in the context of the menopausal transition and postmenopausal years.
- Conditions
- Major Depressive Disorder, Insomnia, Hot Flashes
- Trial name
- NCT00723970
- Testing
- Quetiapine Extended Release
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- McMaster University