Clinical trials: Depression and Quality of Life
Sexuality, Depression
Sexual Health Education During Pregnancy
This experimental, randomized controlled, single-blind study includes intervention and control groups. Pregnant women between 16 and 20 weeks of gestation who meet the inclusion criteria and agree to participate will be included…
- Conditions
- Sexuality, Depression, Pregnancy Related
- Trial name
- NCT07517549
- Testing
- sexuality health education group
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ordu University
Stroke
Efficacy of Music-Based Telerehabilitation After Stroke
The goal of this clinical trial is to learn if a music-based telerehabilitation intervention implemented at home works to treat different kinds of neurological deficits caused by stroke.
- Trial name
- NCT06804304
- Testing
- Music-based telerehabilitation
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Teppo Sarkamo
Osteoarthritis, Knee, Epigenetic Disorder
Exercise on microRNA in Osteoarthritis
The present study is a prospective cohort study. This study will be conducted to determine the change in miRNA levels with exercise in knee Osteoarthritis (OA) patients.
- Conditions
- Osteoarthritis, Knee, Epigenetic Disorder, Quality of Life, Depression
- Trial name
- NCT05869630
- Testing
- Exercise Programme, Experiments
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Cognitive Function, Well-Being
Singing Groups for Seniors: Well-Being, Cognitive Function and Health
The researchers' implement and measure the effects of a singing group intervention program for older adults, with an RCT design, in a natural context, on the health, well-being and cognitive function of older adults.
- Conditions
- Cognitive Function, Well-Being, Physical Function, Respiratory Function
- Trial name
- Sing4Health (NCT03985917)
- Testing
- Singing Group Intervention Program, Alternative Social and Leisure Activities
- Where
- Portugal
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Iolanda Costa Galinha
Prostate Cancer
Mental Wellbeing and Quality of Life in Prostate Cancer
The complex relationship that exists between physical and mental health in prostate cancer is increasingly being understood. Psychiatric symptoms are common in this group and have important consequences for the quality of life…
- Trial name
- MIND-P (NCT04647474)
- Where
- 7 sites in United Kingdom
- Volunteers
- 300 people
- Sponsor
- King's College London
Infertility, Female
The Effect of the Mind/Body Program for Fertility, Hungarian Version, on Well-Being and Assisted Reproduction Outcomes
Involuntary childlessness is an emotionally stressful experience; however, psychosocial counseling is typically not available in Hungarian routine fertility care.
- Trial name
- NCT04151485
- Testing
- Mind/Body Program for Fertility (Domar et al., 2011), Fertility Support Program
- Where
- 2 sites in Hungary
- Volunteers
- 177 people
- Sponsor
- Semmelweis University
Multimorbidity, Older Adults (65 Years and Older)
Integrated Care for Older Adults With Major Depression and Physical Multimorbidity - The I-CONNECT
The goal of this clinical trial is to learn if I-CONNECT (Integrated Care for Older Adults with Major Depression and Physical Multimorbidity) can improve the health and well-being of older adults with depression or bipolar…
- Conditions
- Multimorbidity, Older Adults (65 Years and Older), Mood Disorders, Depression - Major Depressive Disorder
- Trial name
- I-CONNECT (NCT07211750)
- Testing
- integrated care intervention tailored to the needs of older adults leaving at home with mood disorders and multimorbidity in Leuven
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- KU Leuven
Breast Cancer, Depression, Anxiety
Oxidative Stress, Anxiety and Depression in Breast Cancer Patients: Impact of Music Therapy
Oxidative stress plays an important role in the development of breast cancer, and also of depression which can affect the ability to deal with cancer.
- Conditions
- Breast Cancer, Depression, Anxiety, Oxidative Stress
- Trial name
- NCT04446624
- Testing
- Music therapy intervention
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Università degli Studi del Piemonte Orientale Amedeo Avogadro
Mental Health Disorder, Oral Health-Related Quality of Life
Impact of Maternal Mental Health on the Oral Health Status and Oral Health-related Quality of Life of Their Children
Dental caries is a complex multifactorial disease that is strongly related to and influenced by the children's dietary habits, sugar intake, salivary flow, salivary fluoride level, and preventive behaviors.
- Trial name
- NCT05753423
- Testing
- Interview-based questionnaires & Clinical examination
- Where
- Egypt
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cirrhosis of the Liver
HRQoL in the Low MELD Pre-tx Population
The purpose of this study is to describe the HRQoL in those with MELD scores </= 15 in a single center for those who are pre-liver transplant candidates
- Trial name
- LowMELD (NCT01573325)
- Volunteers
- 50 people
- Sponsor
- Northwestern University
Sarcoma, Bone Sarcoma
Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With Sarcoma
The purpose of this study is to investigate the feasibility of early access to mental healthcare during sarcoma treatment as well as to assess the association between early access to psychiatric care and depression, anxiety…
- Conditions
- Sarcoma, Bone Sarcoma, Soft Tissue Sarcoma
- Trial name
- NCT06129903
- Testing
- referral to the Memorial Sloan-Kettering Cancer Center (MSK) Department of Psychiatry and Behavioral Sciences.
- Where
- 8 sites in United States
- Volunteers
- 60 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Depression, Cancer Patients and Depression and Suicide
Improvement of Depression in Terminal Cancer Patients
This study investigates the potential of the water extract of Gastrodia elata Blume (WGE) to alleviate depressive symptoms in terminal cancer patients.
- Conditions
- Depression, Cancer Patients and Depression and Suicide, Life Quality
- Trial name
- IDTCP (NCT06785623)
- Testing
- Gastrodia elata Blume water extract
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
PTSD, Critical Illness
The Experiences of Children and Caregivers Given PICU Storybooks
1. To assess the acceptability and feasibility of a study design aimed at evaluating the efficacy of a newly developed intervention for children and their caregivers following discharge from PICU 2.
- Conditions
- PTSD, Critical Illness, Depression, Anxiety
- Trial name
- NCT04041401
- Testing
- PICU storybook
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Physical Disability, Depression
Prognostication of Need for Rehabilitation and Special Support in ICU Survivors
Title: PROGnostication of need for REhabilitation and Special Support after Intensive Care Unit Stay - a multinational, observational study Objectives: 1.
- Conditions
- Physical Disability, Depression, Posttraumatic Stress Disorder, Anxiety
- Trial name
- PROGRESS-ICU (NCT02679157)
- Where
- 10 sites in Denmark, Netherlands and 1 more
- Volunteers
- 573 people
- Sponsor
- Karolinska University Hospital
Lung Cancer, Depression
Exercise Program Among Lung Cancer Dyads
Pilot study of an exercise program among patients with all stages of lung cancer examining feasibility and acceptability. Preliminary outcomes include objective measures of physical function, depression, adherence to lung cancer…
- Conditions
- Lung Cancer, Depression, Physical Activity, Quality of Life
- Trial name
- PEP-LC (NCT03649737)
- Testing
- Exercise Intervention, Survey Administration, Quality-of-Life Assessment
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- OHSU Knight Cancer Institute
Kidney Failure, Chronic, Depression
Cognitive-behavioral (CBT) in ESRD Patients With Depression
Depression is common in end-stage renal disease (ESRD) patients and has a negative effect on the quality of life, functional ability, and mortality, with a prevalence rate as high as 20-25%.
- Conditions
- Kidney Failure, Chronic, Depression, Quality of Life
- Trial name
- NCT02011139
- Testing
- Cognitive-behavioral group therapy
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Seoul National University Boramae Hospital
Vulvar Cancer, Quality of Life
Quality of Life, Unmet Needs and Satisfaction With Care After Vulvar Cancer
The aim of this prospective, longitudinal Swedish multi-center study is to assess the quality of life, treatment-related morbidity, unmet needs and satisfaction with care after treatment for vulvar cancer, evaluated by a…
- Trial name
- PROVE (NCT04152512)
- Testing
- Questionnaire administration
- Where
- 4 sites in Sweden
- Volunteers
- 153 people
- Sponsor
- Karolinska University Hospital
Breast Cancer, Cancer Survivor
Quality of Life in African-American or Caucasian Female Breast Cancer Survivors
RATIONALE: Studying quality of life in cancer survivors may help determine the long-term effects of breast cancer and may help improve the quality of life for future cancer survivors.
- Conditions
- Breast Cancer, Cancer Survivor, Depression, Fatigue
- Trial name
- NCT00268502
- Testing
- study of socioeconomic and demographic variables, fatigue assessment and management, management of therapy complications
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Indiana University
Human Immunodeficiency Virus, Depression
Community Home-based Care Intervention and Its Health Outcome in HIV-positive People
An intervention study was designed to examine the impact of impact of community home-based care intervention on mental health and treatment outcome in HIV-positive people.
- Conditions
- Human Immunodeficiency Virus, Depression, Stress, Anxiety
- Trial name
- HIV (NCT03505866)
- Testing
- Community home-based care intervention
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Integrated Development Foundation Nepal
Renal Cell Cancer, Colorectal Cancer
Study on the Influence of Sunitinib and Sorafenib on Fatigue, QoL, Depression in Patients With Metastatic RCC or GIST
The purpose of this study is to assess the influence of Sunitinib and Sorafenib on fatigue, quality of life and depression in patients with metastatic renal cell or colorectal cancer or GIST.
- Conditions
- Renal Cell Cancer, Colorectal Cancer, GIST
- Trial name
- NCT00979329
- Testing
- Questionnaires
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Radboud University Medical Center