Clinical trials: Depression and Quality of Life
Cardiology, Psychiatry
Effects of Aerobic Exercise on Cognition,Cerebral Brain Flow and Mental Health Among Traumatic Brain Injury Patients
The aim of this study is to develop exercise prescription of TBI patients and then to evaluate the effectiveness of programmed aerobic walking exercise to improve cognitive performance, depression relief, motivation, symptom…
- Trial name
- NCT04243226
- Testing
- telehealth-based aerobic walking exercise
- Where
- Taiwan
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- National Defense Medical Center, Taiwan
Post COVID-19
Pulmonary and Extrapulmonary Impacts of COVID-19 on Young Adults
When the literature search is conducted, it is seen that there are many studies examining the effects of COVID-19 disease on individuals in various disease groups (MS, stroke, Parkinson, COPD, asthma, etc.) and age groups (adult…
- Trial name
- PEPICov (NCT05282043)
- Testing
- Evaluation of Pulmonary and Extrapulmonary Impacts of COVID-19 on Young Adults
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Istanbul Arel University
Neuropathic Pain
Ketamine and Neuropathic Pain
The primary outcome is to compare the analgesic efficacy of intravenous ketamine treatment to that of a placebo in patients with refractory neuropathic pain. The secondary outcomes are: 1.
- Trial name
- KETAPAIN (NCT02467517)
- Testing
- Ketamine, Magnesium Sulfate
- Where
- France
- Volunteers
- 22 people
- Sponsor
- University Hospital, Clermont-Ferrand
Adult-Onset Growth Hormone Deficiency
Metabolic and QOL Effects of GH Treatment in Patients With TBI and AGHD
This PILOT, NON-INTERVENTIONAL STUDY will follow patients about to start rhGH for a period of six months and collect valuable pilot data to evaluate feasibility of a larger study and treatment tolerability and compliance.
- Trial name
- NCT02988687
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Garcia, Jose M., MD, PhD
Fibromyalgia (FM)
Effects of Immersive Virtual Reality on Quality of Life, Stress, Anxiety, Depression and Grip Strength in Fibromyalgia: A Pilot Study
The aim of this pilot study is to determine the effectiveness of an exercise program based on virtual reality on the impact on quality of life, stress, anxiety, depression and grip strength in people with fibromyalgia.
- Trial name
- NCT06606132
- Testing
- Exercise
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- Universidad San Sebastián
Asthma, Chest Syndrome
Clinical Characteristics and Treatment of Chest Tightness Variant Asthma
Asthma, abbreviation for bronchial asthma, is one of the common chronic airways disease that threatens human health. Typical symptoms of asthma are recurrent wheezing, shortness of breath, chest tightness and cough, usually…
- Conditions
- Asthma, Chest Syndrome, Clinical Anxiety, Clinical Depression
- Trial name
- NCT04322422
- Testing
- Inhaled corticosteriod/long-acting beta-agonist plus Montelukast, Inhaled corticosteriod/long-acting beta-agonist only
- Where
- 33 sites in China
- Volunteers
- 300 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pediatric Cancer, Sickle Cell Disease
FOCUS for Pediatric Sickle Cell Disease and Cancer
Aim. Pilot FOCUS. A pilot randomized controlled trial will compare FOCUS to standard care. Investigators will randomize a total of 60 12- to 18-year-old patients to either FOCUS intervention (n=15 with SCD; n=15 with cancer) or…
- Conditions
- Pediatric Cancer, Sickle Cell Disease, Quality of Life, Depressive Symptoms
- Trial name
- FOCUS (NCT04075877)
- Testing
- FOCUS
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Georgia State University
Dementia, Neurocognitive Disorders
Cognitive Stimulation in Older Adults With Alzheimer's Disease
This multicentre study, employing a randomised controlled repeated measures experimental design, will be conducted in several Portuguese institutions that provide care and support services for older adults diagnosed with mild to…
- Conditions
- Dementia, Neurocognitive Disorders, Cognitive Impairment, Cognitive Dysfunction
- Trial name
- NCT07041008
- Testing
- Digital intervention, Physical/Analogue Intervention
- Where
- 39 sites in Portugal
- Volunteers
- 514 people
- Sponsor
- Rsocialform - Geriatria, Lda
Cognition, Affect (Mental Function)
ETASCAI Pilot Project
This pilot study aims to investigate the chronic effects of ETAS® on cognitive, affective and inflammatory outcomes in healthy adults aged 60-80 years with mild to moderate subjective cognitive complaints.
- Conditions
- Cognition, Affect (Mental Function), Inflammation
- Trial name
- NCT06790849
- Testing
- Active 1 ETAS®, Active 2 ETAS®
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Reading
Prostate Cancer, Sleep
The "PC-LIGHT" Study
Fatigue due to cancer and its treatment (for example, radiation therapy) can interfere with quality of life and can linger long after treatment has ended, yet research examining preventative approaches has produced limited…
- Conditions
- Prostate Cancer, Sleep, Depression, Fatigue
- Trial name
- NCT03419585
- Testing
- Intervention systematic light exposure, Comparison systematic light exposure
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Northwestern University
Cognitive Decline, Osteoarthritis
Healthy Body & Mind Program for Older Adults Living With Osteoarthritis and Cognitive Decline
The goal of this pilot randomised clinical trial is to compare a 12-week Healthy Body \& Mind Program to usual care in older adults living with cognitive decline and osteoarthritis.
- Trial name
- NCT06070818
- Testing
- Healthy Body & Mind Program
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- The University of New South Wales
Epilepsy, Cognitive Dysfunction
Investigation of the Effects of Pilates Training in Patients With Drug-Resistant Epilepsy
This study was planned to examine the effects of Pilates training in patients with drug-resistant epilepsy. It was planned to include 40 epilepsy patients in the study.
- Conditions
- Epilepsy, Cognitive Dysfunction, Seizures, Quality of Life
- Trial name
- NCT06754124
- Testing
- Pilates Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Anxiety Disorders, Anxiety State
Intergenerational Study of War-Affected Youth
War-related violence is a leading driver of mental disorders and illness affecting children in low- and middle-income countries (LMICs).
- Conditions
- Anxiety Disorders, Anxiety State, Depressive Disorder, Mood Disorders
- Trial name
- ISWAY (NCT06440460)
- Where
- Sierra Leone
- Volunteers
- 804 people
- Sponsor
- Boston College
Post-Hysterectomy Vaginal Vault Prolapse
Effects of Deep Breathing Excercises With and Without PMR on Depression & QOL in Females With Hystrectomy
To find out the Effects of deep breathing exercises with and without Progressive Muscle Relaxation Technique on depression and Quality of life in females with hysterotomy
- Trial name
- NCT05460962
- Testing
- Deep breathing excercises, Deep breathing exercises +and progressive muscle relaxation techniques
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Depression
Depression Online Assessment and Therapy
One Aim of the current study is to better understand why some patients suffering from depression do not seek professional help by doctors but in the internet.
- Trial name
- NCT02112266
- Testing
- Mail support, no mail support
- Where
- Switzerland
- Volunteers
- 272 people
- Sponsor
- University of Zurich
Gastrointestinal Neoplasms
Sleep Disturbance, Depressive Symptoms, and Subsequent Quality of Life During Adjuvant Chemotherapy for Gastrointestinal Cancer
This prospective, single-center, non-interventional observational cohort study evaluated longitudinal changes in sleep quality, depressive symptoms, and health-related quality of life among adults receiving fluoropyrimidine-based…
- Trial name
- TRACE-GI (NCT06996483)
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 198 people
- Sponsor
- Ankara Etlik City Hospital
Postpartum Anxiety, Postpartum Depression
Postpartum Screening for Anxiety and Comorbid Conditions
The goal of this project is to facilitate the design of individualized postpartum anxiety (PPA) screening strategies in British Columbia (BC), Canada.
- Conditions
- Postpartum Anxiety, Postpartum Depression, Postpartum Disorder, Postoperative Pain
- Trial name
- PPA (NCT06242717)
- Where
- Canada
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Electromagnetic Emissions and Emotional Disorder, Electromagnetic Emissions and Medication Savings
THE PHYSIOLOGICAL EFFECTS OF ELECTROMAGNETIC EMISSIONS ON THE GENERAL CONDITION OF THE PATIENT
Hospital patients usually experience anxiety caused by physiological, psychological and environmental stimuli. This emotional state corresponds to the psychophysiological response to a perceived threat.
- Trial name
- EPHEME (NCT04301440)
- Testing
- The emission of electromagnetic with the probes, The emission of electromagnetic without the probes
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Clinique Bizet
Sleep
Study to Evaluate Efficacy of Brief Behavioral and Sleep Hygiene Education With Mindfulness Intervention on Sleep Quality
Sleep plays a fundamental role in both mental- and physical-health, with good sleep health including adequate duration and quality, appropriate timing, regularity, and absence of sleep disorders.
- Trial name
- NCT05748496
- Testing
- Brief behavioral sleep therapy, sleep hygiene education and mindfulness training
- Where
- Iceland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Solveig Magnusdottir
Depression, Anxiety Disorders
Prospective Study of the Evaluation of Disease contRol and the Quality of Life of Patients With depressiOn and With or Without aNxiety disOrders in the Greek populatIon
Depression is a psychiatric disorder that affects mood, thoughts and is usually accompanied by physical annoyances. It affects the person's eating habits, his sleep, the way he sees himself and the way he thinks and understands.
- Trial name
- PRONOI (NCT03317262)
- Where
- Greece
- Volunteers
- 800 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.