Clinical trials: Depression and Quality of Life
Mental Health (Depression), Mental Health and General Well-being
Thrive at Home: A Virtual Reality Social Intervention for Older Adults
The goal of this clinical trial is to evaluate whether a virtual reality (VR) based social platform can improve mental health and social connection for older adults who receive in-home care.
- Conditions
- Mental Health (Depression), Mental Health and General Well-being, Loneliness, Well Being
- Trial name
- Thrive at Home (NCT07835568)
- Testing
- Full Virtual Reality Social Intervention, Abbreviated Virtual Reality Social Intervention
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of California, Santa Barbara
Brain Fog, Cognitive Impairment
Cognitive Task-Based Walking Effects on Cognition, Mood, Sleep, and Quality of Life in Older Adults With Brain Fog
This randomized controlled trial aims to investigate the effects of cognitive task-based walking exercise on cognitive function, depressive symptoms, sleep quality, and quality of life in older adults experiencing brain fog.
- Conditions
- Brain Fog, Cognitive Impairment, Geriatric Population
- Trial name
- NCT07396779
- Testing
- Cognitive Task-Based Walking Exercise, Walking-Only Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medipol University
Mental Disorder in Adolescence, Behavioral Symptoms
Effects of Web-Based Training on HbA1c, Quality of Life and Depression Levels in Adolescents With Type 1 Diabetes
Objective: This study was conducted to determine the effect of diabetes training on HbA1c, levels of depression and quality of life of Type 1 Diabetes Mellitus adolescents by using the Web-Based Watson Human Care Model.
- Conditions
- Mental Disorder in Adolescence, Behavioral Symptoms, Problem Behavior
- Trial name
- NCT04888780
- Testing
- The web-based Watson's Human Care Theory oriented training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gaziantep Islam Science and Technology University
Depression, End Stage Renal Disease
CBT to Treat Depression in Renal Patients
The purpose of this study is to determine whether Cognitive Behavioral Therapy is effective in the treatment of depression in patients with end-stage renal disease in hemodialysis therapy
- Trial name
- CBTRPat (NCT00530296)
- Testing
- Cognitive Behavioral Therapy
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Federal University of São Paulo
Fibromyalgia, Covid-19 Fear
The Effects of Covid-19 Pandemic on The Patients With Fibromyalgia
The investigators planned to analyze the effect of Covid-19 fear and anxiety on the daily life, sleep quality and depression-anxiety levels of fibromyalgia patients.
- Conditions
- Fibromyalgia, Covid-19 Fear, Covid-19 Anxiety, Daily Life
- Trial name
- NCT04686578
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Psychological Distress (Depression, Anxiety and Stress) Cancer
Efficacy of an Integrated Psychological Interventions Combined With Ar_Rahman Listening for Reducing Psychological Distress and Enhancing Hope and Quality of Life Among Cancer Patients: A Randomized Controlled Trial
This is a randomized control trial(RCT ID:25142101) to evaluate the efficacy of psychological intervention combined with listening to surah Ar- RAhman for reducing psychological distress and improving cancer patients' hope and…
- Trial name
- NCT07833982
- Testing
- supportive psychotherapy plus QURAN recitation9Surah Ar -Rahman
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Shaheed Zulfikar Ali Bhutto Institute of Science and Technology (SZABIST) University
Cardiovascular Diseases, Coronary Artery Disease
Depressive Symptoms After Cardiac Surgery
The primary goal of this project is to develop a predictive model for clinically significant depressive symptoms (CSDS) in patients undergoing coronary artery bypass graft (CABG) surgery, using pre- and perioperative data.
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Heart Diseases, Depression
- Trial name
- PCD (NCT06706323)
- Where
- 2 sites in Switzerland
- Volunteers
- 300 people
- Sponsor
- Roland von Känel
Functional Dyspepsia, Irritable Bowel Syndrome
Psychoemotional Status and Functional Gastrointestinal Disorders
This prospective cohort study will evaluate the influence of psychoemotional status on the clinical course and quality of life of adult patients with functional dyspepsia and/or irritable bowel syndrome diagnosed according to…
- Trial name
- NCT07539051
- Testing
- Questionnaire and Symptom Assessment, Helicobacter pylori Status Assessment
- Where
- Russia
- Volunteers
- 150 people
- Sponsor
- Center of New Medical Technologies
Alzheimer Disease
Connected Solution of Assistance Dedicated to Caregivers and People With Alzheimer's Disease or Related Diseases
Alzheimer's disease and related diseases (ADRD) are a major public health issue. In France, nearly 900,000 people have ADRD, which represents about 70% of dementia cases, and the expected prevalence for 2020 is 1.2 million.
- Trial name
- Lili smart (NCT03295110)
- Testing
- Functionalities of the Lili Smart Solution activated, Functionalities of the Lili Smart Solution non activated
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hospices Civils de Lyon
Depression, Anxiety Disorders
Prospective Study of the Evaluation of Disease contRol and the Quality of Life of Patients With depressiOn and With or Without aNxiety disOrders in the Greek populatIon
Depression is a psychiatric disorder that affects mood, thoughts and is usually accompanied by physical annoyances. It affects the person's eating habits, his sleep, the way he sees himself and the way he thinks and understands.
- Trial name
- PRONOI (NCT03317262)
- Where
- Greece
- Volunteers
- 800 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Acupressure, Fatigue Syndrome, Chronic
The Effect of Acupressure on Fatigue in Individuals With Chronic Fatigue Syndrome
Chronic fatigue syndrome is a common problem in society. The treatment of this problem is limited. Acupressure is a treatment method that has become widespread and promising in recent years.
- Conditions
- Acupressure, Fatigue Syndrome, Chronic, Complementary Therapies, Quality of Life
- Trial name
- NCT04435002
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Diabetes Mellitus, Diabetes Mellitus, Type 2
Emotional Wellbeing in Diabetes
The investigators want to understand the feasibility and acceptability of implementing COMPASS: Online Cognitive behavioural therapy (CBT) in routine NHS care for individuals with diabetes.
- Conditions
- Diabetes Mellitus, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Diabetes
- Trial name
- NCT05140551
- Testing
- COMPASS: digital CBT
- Where
- 4 sites in United Kingdom
- Volunteers
- 12 people
- Sponsor
- King's College London
Mild Cognitive Impairment (MCI), Depression
Brain Aging and Treatment Response in Geriatric Depression
The proposed project will evaluate the role of neuroimaging biomarkers of brain aging (i.e., neurodegenerative and vascular brain changes) and mild cognitive impairment in the patterns of treatment response to memantine combined…
- Trial name
- NCT01902004
- Testing
- Escitalopram, Memantine
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of California, Los Angeles
Thyroid Nodule
Health-Related Quality of Life and Emotions in Patients with Thyroid Nodules
The purpose of this observational research is to evaluate and compare the health-related quality of life and emotional well-being of patients with thyroid nodules before and after treatment.
- Trial name
- NCT06610604
- Testing
- thermal ablation, thyroidectomy
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ming-an Yu
Analgesia, Anxiety
The Effect of Hypnosis in Fibromyalgia
Fibromyalgia syndrome (FMS) is a chronic disease characterized by widespread pain of unknown origin, fatigue, sleep disturbances, and cognitive problems.
- Conditions
- Analgesia, Anxiety, Depression, Hypnosis
- Trial name
- NCT05861518
- Testing
- Hypnosis
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Post-Hysterectomy Vaginal Vault Prolapse
Effects of Deep Breathing Excercises With and Without PMR on Depression & QOL in Females With Hystrectomy
To find out the Effects of deep breathing exercises with and without Progressive Muscle Relaxation Technique on depression and Quality of life in females with hysterotomy
- Trial name
- NCT05460962
- Testing
- Deep breathing excercises, Deep breathing exercises +and progressive muscle relaxation techniques
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Hematopoietic Stem Cell Transplantation, Cognitive Impairments
The "Light for the Brain" Study
Cognitive impairment (such as memory problems) due to cancer and its treatment can interfere with quality of life and can linger long after treatment has ended, yet research examining cognitive rehabilitation approaches has…
- Conditions
- Hematopoietic Stem Cell Transplantation, Cognitive Impairments, Sleep, Depression
- Trial name
- NCT02677987
- Testing
- Intervention systematic light exposure, Comparison systematic light exposure
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Northwestern University
Depression
The Preventive Effect of Escitalopram on Depression and Related Emotional Disorders in Acute Stroke Patients
Through this study, the investigators are to demonstrate the superiority of Escitalopram over placebo for the prevention of poststroke depression in patients with acute stroke The primary hypothesis of this study is; This study…
- Trial name
- EMOTION (NCT01278498)
- Testing
- Escitalopram, sugar pill
- Where
- 16 sites in South Korea
- Volunteers
- 444 people
- Sponsor
- Asan Medical Center
Depression, Cognition
Feasibility and Efficacy of a Digital Neurotherapy Protocol for Management of Depression, Cognition, and Quality of Life in Cancer Survivors
This is a prospective, randomized clinical study to evaluate the feasibility and efficacy of a digital neurotherapy on depression, cognition, and quality of life in two groups of patients with major medical illness: 1) a sample…
- Conditions
- Depression, Cognition, Quality of Life
- Trial name
- NCT04961047
- Testing
- Digital neurotherapy (DNT) Treatment, Wait list control group
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Yale University
Diabetic Peripheral Neuropathy
Effect of an Exercise Program on Clinical Aspects of People With Diabetic Peripheral Neuropathy
Diabetic Peripheral Neuropathy (DPN) is one of the most prevalent and debilitating complications of type 2 diabetes mellitus (DM2), especially affecting the distal region of the lower limbs.
- Trial name
- NCT07075367
- Testing
- Proximal/distal protocol, Distal protocol
- Volunteers
- 64 people
- Sponsor
- Federal University of Piaui