Clinical trials: Depression and Suicide Ideation
Suicide, Mental Health Disorder
A Digitally Assisted Risk Reduction Platform for Youth at High Risk for Suicide
Despite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death among youth. Digital tools, especially personal smartphones, are promising avenues to address these issues and can be…
- Conditions
- Suicide, Mental Health Disorder, Anhedonia
- Trial name
- NCT05920252
- Testing
- Vira, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Ksana Health
Depression, Mental Disorder in Adolescence
Study of Web- Based Cognitive Behavioral Therapy for Depressed Korean Adolescents
The purpose of this study is to develope web-based cognitive behavioral therapy for Korean adoldescents who have a mild depression.
- Conditions
- Depression, Mental Disorder in Adolescence, Cognitive Behavioral Therapy
- Trial name
- wogyeokdajim (NCT02072304)
- Testing
- web-based CBT, supportive care
- Where
- 3 sites in South Korea
- Volunteers
- 164 people
- Sponsor
- Hallym University Medical Center
Depression, Suicidal Ideation
Emergency Ketamine Treatment of Suicidal Ideation
The objective of the current program of research will be to test whether intranasal ketamine treatment is more effective than placebo in reducing suicidal ideation in suicidal patients presenting for acute treatment in emergency…
- Conditions
- Depression, Suicidal Ideation, Suicidal Impulses
- Trial name
- NCT02183272
- Testing
- Intranasal Ketamine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Cincinnati
Recreational Drug Use, Sexual Violence
Evaluation of Teen Connection Project for Trans and Gender Minority Youth
The purpose of this project is to develop and evaluate an online mentoring and skill-building program for transgender and/or gender minority youth (TGMY) ages 14 to 18, the Teen Connection Project (TCP).
- Conditions
- Recreational Drug Use, Sexual Violence, Victimisation, Depressive Symptoms
- Trial name
- TCP (NCT06587139)
- Testing
- Teen Connection Project (TCP)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Domestic Violence, Post-Traumatic Stress Disorder
Mental Health Symptoms and Intimate Partner Violence
Using a touch screen computer, the researchers are screening emergency department patients for intimate partner violence and mental health issues.
- Conditions
- Domestic Violence, Post-Traumatic Stress Disorder, Depression
- Trial name
- NCT00166075
- Testing
- Computer screen with community resource printout
- Where
- United States
- Volunteers
- 569 people, healthy volunteers welcome
- Sponsor
- Emory University
Depressive Disorder
M3VAS Validation in Polish Population
Low mood and anhedonia represent the fundamental symptoms of major depressive disorder (MDD). Nevertheless, there is currently no standardized visual analogue scale available to assess the extent of both symptoms concurrently.
- Trial name
- NCT06412562
- Testing
- The Maudsley 3-item Visual Analogue Scale (M3VAS)
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Medical University of Gdansk
Borderline Personality Disorder
Magnetic Seizure Therapy for the Treatment of Borderline Personality Disorder
Suicide is a major public health crisis for which effective new interventions are needed. An innovative new brain stimulation technique called magnetic seizure therapy (MST) shows promise for treating suicidal thinking in…
- Trial name
- NCT03361826
- Testing
- MagPro MST with Cool TwinCoil, DBT
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- Centre for Addiction and Mental Health
Depression, Suicide
Concurrent Treatment for Depressed Parents and DepressedAdolescents
This study will develop an integrated treatment for adolescents who are depressed and suicidal and their parents who are depressed and have a history of suicidality.
- Trial name
- NCT00951821
- Testing
- Concurrent treatment, Adolescent treatment only
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Brown University
Depression, Suicide
Youth Depression and Suicide Research Network
The objective of this study is to build the Texas Youth Depression and Suicide Research Network to support the development of a Network Participant Registry and characterization of systems and interventions to examine statewide…
- Conditions
- Depression, Suicide, Suicidal Ideation, Suicide, Attempted
- Trial name
- YDSRN (NCT04572321)
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- University of Texas Southwestern Medical Center
Suicide, Suicidal Ideation
Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department
There is currently no readily available pharmacologic intervention for suicidal ideation, a true psychiatric emergency, in the Emergency Department (ED).
- Conditions
- Suicide, Suicidal Ideation, Depression
- Trial name
- NCT06085937
- Testing
- Ketamine
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Lindsay Maguire, MD
Older Adults (50-90 Years), Mental Health
Project HOPEFUL: A PN-RCT With Implementation Science
This PN-RCT replicates and evaluates an 8-week warm calling treatment (i.e. caring contacts) delivered to older adults receiving home and community-based services (HCBS; classified as "homebound") in 20-30 minute call "dosages"…
- Conditions
- Older Adults (50-90 Years), Mental Health, Depression and Suicide Ideation, Social Functioning
- Trial name
- NCT07475039
- Testing
- Standardized and manualized warm calls from providers trained in the BE training, Standardized and manualized warm calls from providers trained in the BE training + ASIST training
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Florida
Reduction in Mental Health and Suicide Are the Focus of Interest, Four Assessment Time Points Would be Used to Monitor Participants Through a Laid Down Conditions
Cognitive Resilience Intervention as a Recovery Therapy for Mental Health
The goal of this randomized controlled trial (RCT) is to develop and test a cognitive resilience intervention (CRI) among selected students who are having problems with anxiety, depression, and suicidal thoughts (psychological…
- Trial name
- CRI (NCT06123442)
- Testing
- Cognitive Resilience Intervention
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Universidad Autonoma de Ciudad Juarez
Borderline Personality Disorder (BPD), Treatment-Resistant Major Depressive Disorder
Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)
The goal of this clinical trial is to learn if intravenous (IV) ketamine with Dialectical Behavioural Therapy (DBT) reduces suicidal ideation in individuals with suicidality who have been diagnosed with Borderline Personality…
- Conditions
- Borderline Personality Disorder (BPD), Treatment-Resistant Major Depressive Disorder, Treatment-resistant Bipolar Depression, Major Depressive Disorder (MDD)
- Trial name
- KET-DBT (NCT07569198)
- Testing
- Ketamine Hydrochloride, Midazolam Hydrochloride, Dialectical Behavioral Therapy (DBT)
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Joshua Rosenblat
Suicidal Ideation, Major Depressive Disorder
The Effect of Ketamine on Mechanises Underlying Suicidal Ideation and Drug-resistant Major Depression
Suicide attempts are a serious concern worldwide. Currently, existing drugs take about three weeks to show effect on suicidal thoughts and drives.
- Conditions
- Suicidal Ideation, Major Depressive Disorder, Healthy Participants
- Trial name
- NCT02037503
- Testing
- Ketamine, Saline
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Depression - Major Depressive Disorder, Depression Disorder
Link Between Reduction of Suicide Ideation by Esketamine in Add-On and Initial Levels of Psychological Pain and Anhedonia
This study is looking at how intranasal esketamine (a nasal spray) can help reduce suicidal thoughts in patients with severe depression who are experiencing suicidal thoughts.
- Conditions
- Depression - Major Depressive Disorder, Depression Disorder, Suicide
- Trial name
- IODA (NCT07199179)
- Where
- France
- Volunteers
- 456 people
- Sponsor
- University Hospital, Montpellier
Depression, Suicidal Ideation
Identification of Genetic Markers and Predictors of Antidepressant-induced Suicidality in Youth Depression
The objective of this study is to identification of genetic markers and predictors of antidepressant-induced suicidality in youth depression.
- Trial name
- NCT02428439
- Testing
- bupropion or lamotrigine
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Asan Medical Center
Major Depression, Mania
Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)
The primary aims of this study are to assess: 1. The inter-rater and test-retest reliability of the MINI-KID 2. The validity of the standard MINI-KID interview in relation to the parent rated pencil/paper version (MINI-KID-P) and…
- Conditions
- Major Depression, Mania, Anxiety Disorders, Psychotic Disorder
- Trial name
- NCT00579267
- Testing
- MINI-KID
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Suicide Ideation, Suicidal Behaviors
A New Clinical Model for the Engagement of Latinx Youth With Suicidal Behavior
This study will test a model of providing treatment to Latinx/Hispanic youth, who experience suicidal thoughts and behavior, and their caregivers.
- Conditions
- Suicide Ideation, Suicidal Behaviors, Depressive Symptoms
- Trial name
- NCT06882798
- Testing
- Socio-Cognitive Behavioral Therapy for Suicidal Behavior (SCBT-SB), SCBT-SB + CHW
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Bradley Hospital
Suicide Risk
MIN PLAN VS CBT for Suicide Prevention
1. To investigate the effectiveness of Young Adults Culturally Adapted Manual Assisted Psychological Therapy (YA-CMAP) in University students with Suicide Risk 2.
- Trial name
- NCT05095233
- Testing
- Young Adults Culturally Adapted Manual Assisted Psychological Therapy (YA-CMAP), Min Plan Tool
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Syeda AYAT E ZAINAB Ali
Depression, Anxiety, Suicidal Ideation
A Trauma-Informed Approach for Positive Youth Development for Montana Students
Given the prevalence of suicide and mental health issues in rural Montana, this project is intended to help mitigate stressors that may contribute to poor behavioral and mental health in high school-aged children.
- Conditions
- Depression, Anxiety, Suicidal Ideation, Stress, Trauma
- Trial name
- NCT04664855
- Testing
- Trauma-Informed Yoga
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Montana State University