Clinical trials: Depression in Remission
Repetitive Negative Thinking, General Anxiety Disorder
Training Protocol 'Drop it'. The Impact of a Training Protocol Focused on Coping With Negative Repetitive Thinking on Cognitive and Behavioural Functioning of People Suffering From GAD or Minor or Moderate Depressive Disorder or Depressive Disorder in Remission
Repetitive negative thinking (RNT) plays an important role in different psychiatric disorders, such as depressive and anxiety disorders, complicated grief, posttraumatic stress disorders, anorexia nervosa.
- Conditions
- Repetitive Negative Thinking, General Anxiety Disorder, Depressive Disorder, Depression
- Trial name
- Drop It (NCT01983033)
- Testing
- Drop It training session, treatment as usual
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- University Hospital, Ghent
Unipolar Depressed Outpatients, Mild Severity
Effectiveness of the First French Psychoeducational Program on Unipolar Depression
Background. Major Depressive Disorder (MDD) is highly prevalent and was associated with greater morbidity, mortality (including suicide), and healthcare costs.
- Conditions
- Unipolar Depressed Outpatients, Mild Severity, Without Psychotic Features
- Trial name
- PURE (NCT02501226)
- Testing
- Treatment as usual, ENVIE psychoeducational program
- Where
- France
- Volunteers
- 332 people
- Sponsor
- University Hospital, Montpellier
Bipolar Disorder
Circadian Phase in Bipolar Depression: Is it Delayed and Does it Normalize With Remission?
The overall aim of this project is to compare sleep patterns and melatonin profiles in individuals with bipolar disorder during depression and after remission.
- Trial name
- NCT01784341
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Northwestern University
Major Depressive Disorder
SPD489 in Adults With Persistent Executive Function Impairments (EFI) and Partial or Full Remission of Recurrent Major Depressive Disorder
To evaluate the efficacy of SPD489 for the treatment of executive function impairments (EFI) when used as an adjunct to stable, standard therapy in the setting of partial or full remission from recurrent Major Depressive Disorder…
- Trial name
- NCT00985725
- Testing
- SPD489 (Lisdexamfetamine dimesylate)
- Where
- 33 sites in United States
- Volunteers
- 143 people
- Sponsor
- Shire
Major Depression (in Remission)
Investigating the Mechanisms of Mindfulness-based Cognitive Therapy (MBCT)
This research will investigate the neuropsychological mechanisms underlying the eight-week Mindfulness-based Cognitive Therapy (MBCT) programme.
- Trial name
- NCT02226042
- Testing
- Mindfulness-based Cognitive Therapy
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Major Depressive Disorder
Efficacy of Vortioxetine on Cognitive Dysfunction in Patients With Partial or Full Remission of Major Depressive Disorder
To assess the efficacy of vortioxetine (10 to 20 mg/day) as adjunctive treatment to stable selective serotonin reuptake inhibitor (SSRI) dose versus stable SSRI monotherapy on cognitive performance (focusing on the aspect…
- Trial name
- NCT02279953
- Testing
- Vortioxetine 10-20 mg, SSRI
- Where
- 17 sites in Estonia, Finland and 3 more
- Volunteers
- 151 people
- Sponsor
- H. Lundbeck A/S
Depressive Disorder, Major, Recurrence
Study Evaluating Venlafaxine ER in Recurrent Depression
The purpose of this study is to review the long-term comparative efficacy of venlafaxine ER in achieving and sustaining remission (wellness) in patients with recurrent major depression
- Trial name
- NCT00046020
- Testing
- Venlafaxine ER
- Volunteers
- 1,096 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Major Depressive Disorder (MDD)
Electroencephalography-based Precise Repetitive Transcranial Magnetic Stimulation Treatment
This study will focus on the hypothesis that repetitive transcranial magnetic stimulation (TMS) based on EEG personalized modulation may be more effective in promoting symptomatic relief of major depressive disorder (MDD), and…
- Trial name
- NCT06385405
- Testing
- Individualized alpha frequency Transcranial Magnetic Stimulation (αTMS) Treatment, 10Hz-frequency TMS treatment over the left dorsolateral prefrontal cortex (DLPFC)
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Shanghai Mental Health Center
Cognitive Remediation, Cognitive Impairment
Internet-delivered Intervention Targeting Residual Cognitive Symptoms After Major Depressive Disorder
Background: Cognitive impairment and difficulties are frequently observed in individuals suffering from major depressive disorder. These impairments and difficulties can persist into remission as residual cognitive symptoms.
- Conditions
- Cognitive Remediation, Cognitive Impairment, Major Depression in Remission
- Trial name
- RestDep (NCT04864353)
- Testing
- RestDep: Internet-delivered intervention targeting residual cognitive symptoms
- Where
- Norway
- Volunteers
- 44 people
- Sponsor
- Haukeland University Hospital
Lung Cancer
Maximal Exercise Capacity and Extra-pulmonary Characteristics in Patients With Lung Cancer With Complete Remission .
While lung cancer are rare disease in the early 20th century, its incidence increased in parallel with the increase in smoking habits. It is the most common type of cancer in the world.
- Trial name
- NCT03838757
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gazi University
Major Depression
Predictors of the Outcome of Late Life Depression
Predictors of response to pharmacological treatment of major depressive disorder will be investigated. One hundred and twenty patients will be included in a naturalistic clinical trial.
- Trial name
- NCT02441387
- Testing
- Antidepressant, Psychoeducation, Treatment as usual (only pharmacological treatment).
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Sao Paulo General Hospital
Bipolar Disorder in Remission, Major Depression in Remission
Seasonality, Chronotype, Impulsivity, and Suicidality in Mood Disorder Patients
The aim of the study is to examine the seasonal variation of suicidal ideation in patients with mood disorders and the trajectory of impulsivity and suicidal ideation in patients with higher seasonality.
- Trial name
- NCT07857213
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul University - Cerrahpasa
Bipolar Depression
What is the Antidepressant Mechanism of Action of Quetiapine in Bipolar Depression?
PURPOSE The purpose of this study is to elucidate whether quetiapine fumurate (Seroquel) exerts its antidepressant activity in bipolar disorder through altering either serotonergic or catecholinergic activity.
- Trial name
- NCT00817323
- Testing
- Dietary amino-acid depletion
- Sponsor
- University of British Columbia
Major Depressive Disorder
Algorithm Guided Treatment Strategies for Major Depressive Disorder
The purpose of this study is to compare treatment outcomes between measurement based Algorithm Guided Treatment and Treatment As Usual strategies in a Chinese population with major depressive disorder.
- Trial name
- AGTs-MDD (NCT01764867)
- Testing
- Escitalopram, Mirtazapine, modified electroconvulsive therapy
- Where
- China
- Volunteers
- 1,080 people
- Sponsor
- Shanghai Mental Health Center
Major Depressive Disorder
Follow-up Study of Transcranial Direct Current Stimulation to Treat Major Depressive Disorder
The investigators purpose is to follow remitted patients from their previous study using transcranial direct current stimulation (tDCS); as to verify whether this treatment prevents relapse.
- Trial name
- NCT01149213
- Testing
- transcranial direct current stimulation
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- University of Sao Paulo
Cancer in Remission (Any Type or Stage), Depression
Repetitive Transcranial Magnetic Stimulation in Cancer Patients With Depression and Anxiety
Cancer is a leading cause of mortality and morbidity worldwide. In addition, cancer is associated with high rates of depression and anxiety among its sufferers, and cancer patients with depression usually have worse treatment…
- Conditions
- Cancer in Remission (Any Type or Stage), Depression, Anxiety
- Trial name
- rTMSinCP (NCT01701284)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Northwestern University
Bipolar Depression, Suicidal Ideation
NRX-101 for Maintenance of Remission From Severe Bipolar Depression in Patients With Suicidal Ideation
NMDA antagonist drugs have increasingly been demonstrated to reduce symptoms of depression and suicidal ideation. NeuroRx has developed a sequential therapy consisting of IV NRX-100 (ketamine HCL) for rapid stabilization of…
- Trial name
- SBD-ASIB (NCT03396068)
- Testing
- NRX-101, Lurasidone HCl
- Where
- 4 sites in United States
- Volunteers
- 72 people
- Sponsor
- NeuroRx, Inc.
Inflammatory Bowel Diseases, Functional Gastrointestinal Disorders
Functional Gastrointestinal Disorders in Pediatric IBD
Background: Persistent gastrointestinal symptoms have been described in patients who are considered in remission of their inflammatory bowel disease (IBD).
- Conditions
- Inflammatory Bowel Diseases, Functional Gastrointestinal Disorders, Pediatric Disorder, Anxiety Depression
- Trial name
- TFI-MICI (NCT03565263)
- Where
- France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Caen
Major Depressive Disorder
Study Comparing Remission Rates, in Patients With Major Depressive Disorder (MDD)
Tools known as 'depression scales 'are widely used as assessments to evaluate a patient's response to treatment. The purpose of this study is the evaluation of the remission rates for patients with MDD.
- Trial name
- B2411003 (NCT00770289)
- Testing
- Cohort
- Where
- 3 sites in Greece
- Volunteers
- 851 people
- Sponsor
- Pfizer
Major Depression in Remission
Effects of Booster Sessions on Depression Vulnerability Following Cognitive Control Training
The current study aims to examine the impact of booster sessions of cognitive control training (CCT) on indicators of depression vulnerability.
- Trial name
- NCT05557760
- Testing
- Cognitive Control Training (CCT), Cognitive Control Training (CCT) + Booster Sessions
- Where
- 2 sites in Belgium
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University Ghent