Clinical trials: Depressive; Behavioral Disorder
Bone Diseases, Metabolic, Depression, Involutional
Use of Bone Biopsy to Better Understand the Causes of Decreased Bone Mineral Density in Depression
In this study researchers would like to learn more about the low levels of bone mineral density seen in approximately half of women in their forties diagnosed as currently having or previously had depression.
- Conditions
- Bone Diseases, Metabolic, Depression, Involutional, Osteoporosis
- Trial name
- NCT00001916
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- National Institute of Mental Health (NIMH)
Diabetes Mellitus Type 2, Continuous Glucose Measurement
Effectiveness of Individualized Automatic Coaching Message for Glycemic Management and Depressive Symptom
This is a 12-week, single-center, randomized, prospective, confirmatory study of effectiveness of the individualized automatic coaching messages for glycemic management based on continuous glucose monitoring and depressive…
- Conditions
- Diabetes Mellitus Type 2, Continuous Glucose Measurement, Depressive Symptom
- Trial name
- NCT06769906
- Testing
- Individualized automatic coaching message for glycemic management and depressive symptom
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Samsung Medical Center
Depression
Motivational Interviewing to Improve Medication Adherence Among Hispanic Adults With Depression
This study will determine the effectiveness of motivational interviewing in improving antidepressant medication adherence among Hispanics.
- Trial name
- NCT00356304
- Testing
- Motivational interviewing, Treatment as usual
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Mobility, Depressive Symptoms
Effectiveness of AMICOPE Intervention to Maintain Self-Perceived Health and Intrinsic Capacity in Older People
In their day to day, persons do from simple to more or less complicated tasks and activities (ie: stand from a chair, open a door, shopping, read, drive, play chess, remind an appointment...).
- Conditions
- Mobility, Depressive Symptoms, Nutrition, Healthy, Cognitive Decline
- Trial name
- EFICIS (NCT05249504)
- Testing
- VIVIFRAIL, Nutrition, Psychology
- Volunteers
- 212 people
- Sponsor
- Fundacio Salut i Envelliment UAB
Myasthenia Gravis, Depression
Depressive Tendency and Counseling Outcomes in Thymoma-Associated MG
This study aimed to examine whether baseline depressive tendency independently predicts post-counseling clinical outcomes in patients with thymoma-associated MG.
- Conditions
- Myasthenia Gravis, Depression, Thymoma, Depression and Quality of Life
- Trial name
- NCT07649187
- Testing
- Psychological counseling intervention
- Where
- Taiwan
- Volunteers
- 19 people
- Sponsor
- Ming-Hsing Chang
Bipolar Disorder, Depression
Early Detection and Prevention of Mood Disorders in Children of Parents With Bipolar Disorder
This study will develop strategies for early detection and prevention of mood disorders and associated impairment in adolescent children of parents with bipolar disorder.
- Trial name
- NCT00338806
- Testing
- Interpersonal psychotherapy for prevention with adolescents, Educational clinical monitoring
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- New York State Psychiatric Institute
Depression, Mental Health Disorder
e-Mindfulness for Depression in Older Adults
This pilot study will test whether depression symptoms and cognitive functioning are impacted by internet-delivered mindfulness training following the principles of mindfulness meditation.
- Trial name
- MMW (NCT03922217)
- Testing
- Mindful My Way
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Washington University School of Medicine
Major Depressive Disorder
A Study to Evaluate the Safety, Tolerability and Efficacy of XEN1101 in Major Depressive Disorder
This is a multicenter, Phase 2, double-blind, randomized, parallel-arm, placebo-controlled clinical trial to evaluate the efficacy, safety, and tolerability of XEN1101 in subjects with Major Depressive Disorder.
- Trial name
- X-NOVA (NCT05376150)
- Testing
- XEN1101 10 mg, XEN1101 20 mg
- Where
- 20 sites in United States
- Volunteers
- 168 people
- Sponsor
- Xenon Pharmaceuticals Inc.
Depression, Unipolar, Depressive Disorder
Gaze Contingent Feedback in Major Depressive Disorder (MDD)
The purpose of this study is to determine whether giving gaze-contingent feedback is an effective attention modification procedure, helping in the treatment of Major Depressive Disorder (MDD)
- Conditions
- Depression, Unipolar, Depressive Disorder, Depressive Disorder, Major
- Trial name
- NCT02945735
- Testing
- Attention Modification
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Tel Aviv University
Depression, Postpartum, Depression
Using a Preparation and Education Intervention to Reduce Postpartum Depression Among New Mothers (The MADE IT 2 Study)
This study will test an intervention that aims to prevent postpartum depression by providing new mothers with information on and resources for dealing with the disorder.
- Trial name
- NCT00951717
- Testing
- Behavioral education intervention
- Where
- United States
- Volunteers
- 590 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Depression, Depressive Disorder
Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) vs. Escitalopram in Postmenopausal Women
Desvenlafaxine succinate (DVS) is a potent and selective serotonin and norepinephrine reuptake inhibitor (SNRI). This study will investigate the safety, efficacy, and tolerability of DVS SR versus escitalopram in women with major…
- Conditions
- Depression, Depressive Disorder, Depressive Disorder, Major
- Trial name
- NCT00406640
- Testing
- Desvenlafaxine succinate sustained-release (DVS SR), Escitalopram
- Where
- 70 sites in United States, Argentina and 4 more
- Volunteers
- 595 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Major Depressive Disorder (MDD)
Home-Based tDCS Treatment Of Major Depressive Disorder
The REACH-tDCS study will evaluate the safety and efficacy of a noninvasive, at-home self-administered Sooma tDCS brain stimulation treatment for Major Depressive Disorder.
- Trial name
- REACH-tDCS (NCT06976697)
- Testing
- Transcranial direct current stimulation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Sooma Medical Inc
Major Depressive Disorder
Mindbeacon Therapist Assisted Internet Delivered CBT for Depression
Utilization of therapist Assisted internet-delivered cognitive behavioural therapy (TAiCBT) for treating depression and anxiety disorders in stepped-care models, such as the UK's Improving Access to Psychological Therapies (IAPT)…
- Trial name
- NCT05134103
- Testing
- Mindbeacon Therapist Guided, Internet Cognitive Behavioral Therapy for Depression, Waitlist Control Group
- Sponsor
- Ontario Shores Centre for Mental Health Sciences
Depressive Disorder
An Eight-Week Study to Evaluate the Efficacy and Safety of Saredutant in Patients With Depression
The purpose of the study is to evaluate the efficacy and safety of saredutant (or SR48968C) in patients with depression. The primary objective is to evaluate the efficacy of a 100 mg dose of saredutant compared to placebo in…
- Trial name
- NCT00250627
- Testing
- Saredutant succinate (SR48968C)
- Where
- 8 sites in Canada, Chile and 6 more
- Volunteers
- 465 people
- Sponsor
- Sanofi
Moderate Depression, Major Depressive Disorder
pBFS Guided 20min Inter-session Interval rTMS Treatment for MDD
The investigators aim to explore the efficacy and safety of rTMS therapies with different intervals between sessions for treating patients with moderate to severe depression.
- Conditions
- Moderate Depression, Major Depressive Disorder, Severe Depression
- Trial name
- NCT05957341
- Testing
- active rTMS: 20min inter-session interval, active rTMS: 50min inter-session interval
- Volunteers
- 50 people
- Sponsor
- Changping Laboratory
Prader-Willi Syndrome, Obesity
Effects of Transcranial Direct Current Stimulation (tDCS) on Individuals With Prader-Willi Syndrome
Prader-Willi Syndrome (PWS) is a multisystemic genetic disease characterized by hypotonia, mental retardation, hyperphagia, and uncontrollable hunger due to hypothalamic dysfunction, caused by dysregulation of genes located in…
- Conditions
- Prader-Willi Syndrome, Obesity, Depressive Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT03324906
- Testing
- tDCS
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
Major Depressive Disorder
AZD7268 Safety and Tolerability Study
The purpose of this study is to prove the principle that treatment with AZD7268 reduces depressive symptoms in patients with Major Depressive Disorder (MDD) compared with placebo.
- Trial name
- NCT01020799
- Testing
- AZD7268, Escitalopram
- Where
- 17 sites in United States
- Volunteers
- 247 people
- Sponsor
- AstraZeneca
Major Depressive Disorder
Vagus Nerve Stimulation: Integration of Behavior and Cardiac Modulation
This study characterized the impact of respiratory-gated transcutaneous vagus nerve stimulation (tVNS) on the modulation of the stress response circuitry, vagal tone and depressed mood in patients with major depressive disorder…
- Trial name
- tVNS-MDD (NCT04467164)
- Testing
- exhalatory-gated transcutaneous vagus nerve stimulation (e-RAVANS), Inhalatory-gated transcutaneous vagus nerve stimulation (i-RAVANS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Cannabis Use Disorder, Depressive State
Substance Misuse To Psychiatric Disorders for Cannabis
With the recent availability of vortioxetine, and the surging phenomenon of cannabis misuses amongst young abusers, it is a timely opportunity to conduct an early pharmacotherapy intervention study to offer an evidence-based…
- Conditions
- Cannabis Use Disorder, Depressive State, Anxiety State, Depression
- Trial name
- NCT03485274
- Testing
- Vortioxetine, Treatment as Usual
- Where
- Hong Kong
- Volunteers
- 37 people
- Sponsor
- The University of Hong Kong
Depression
Hyperventilation Combined With Etomidate or Ketamine Anesthesia in ECT Treatment of Major Depression
This is a randomized controlled study assessing the effect of pre-emptive hyperventilation on ECT seizure duration, cerebral desaturation and remission of depressive symptoms in patients with Major Depressive Disorder.
- Trial name
- NCT02924090
- Testing
- Etomidate, Ketamine, Hyperventilation
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University of Manitoba
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