Clinical trials: Depressive; Behavioral Disorder
Cancer Breast, Colon Cancer
The Effect of Acceptance and Commitment Approach-Based Psychoeducation in Cancer Survivors
The study is planned to be conducted in a randomised controlled experimental design in accordance with CONSORT. The study is planned to be conducted between September 2025 and December 2026 at X Hospital with individuals who have…
- Conditions
- Cancer Breast, Colon Cancer, Cancer Survivors
- Trial name
- NCT07205965
- Testing
- Experimental Group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Stroke, Depressive Symptoms
The Effect of Instant Message Intervention for Psychological Well-being Among Stroke Survivors
The proposed pilot trial aims to evaluate the feasibility of iCBT based EMI, which is a real-time, real-world, personalised and cost-effective approach, for stroke survivors' psychological well-being.
- Conditions
- Stroke, Depressive Symptoms, Mobile Phone Use
- Trial name
- NCT05490069
- Testing
- iCBT-based EMI
- Where
- 7 sites in Hong Kong
- Volunteers
- 40 people
- Sponsor
- The University of Hong Kong
Depressive Disorder, Major
Abilify as an Adjunctive Treatment for Refractory Depression
This is a study of the effectiveness of adding Abilify (aripiprazole), an atypical antipsychotic medication, to ongoing selective serotonin reuptake inhibitor (SSRI) antidepressant treatment for depressed outpatients who are not…
- Trial name
- NCT00220636
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Chronic Disease, Depressive Symptoms
Bio-psycho-social Pathways Underlying the Effects of Qigong Among Comorbid Depressed Elderly With Chronic Conditions
Depression and chronic medical conditions are common in older adults. Qigong is increasingly documented to have anti-depressive effects for older adults. Nevertheless, the scientific concepts behind qigong remain a mystery.
- Trial name
- NCT03591211
- Testing
- Qigong Training, Cognitive Training
- Where
- Hong Kong
- Volunteers
- 35 people
- Sponsor
- The Hong Kong Polytechnic University
Depressive Disorder, Cardiac Diseases
Qigong Therapy For Heart Device Patients
The goal of this study is to improve the overall physical health and quality of life of patients attached to mechanical heart devices while awaiting heart transplantation.
- Trial name
- NCT00027001
- Testing
- Aerobic and Resistance Exercises, Qigong
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Depression - Major Depressive Disorder, Resilience
Evaluating The Impact of A Mental Health App on Depression and Resilience Among Medical Students
This randomized controlled trial aims to determine whether access to a mental health app improves resilience and reduces depressive symptoms among medical students over a three-month period.
- Trial name
- NCT07397299
- Testing
- Full digital mental health intervention, Basic digital mental health intervention
- Where
- Malaysia
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Depressive Disorder
An Eight-Week Study to Evaluate the Efficacy and Safety of SR58611A in Elderly Patients With Depression
The purpose of the study is to evaluate the efficacy and safety of SR58611A in elderly patients with depression.The primary objective is to evaluate the efficacy of a 700 mg dose of SR58611A compared to placebo in elderly…
- Trial name
- ZEPHIR (NCT00319709)
- Testing
- SR58611A
- Where
- 5 sites in Bulgaria, Finland and 3 more
- Volunteers
- 288 people
- Sponsor
- Sanofi
Major Depressive Disorder, Depression
Investigating Predictors of Treatment Response in Treatment-Resistant Depression (TRD) With Interleaved TMS/fMRI
The purpose of this trial is identify biomarkers of response to repetitive transcranial magnetic stimulation (rTMS) in individuals with first episode or treatment resistant depression.
- Trial name
- NCT03642522
- Testing
- repetitive transcranial magnetic stimulation
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Depressive Symptoms, Anxiety Disorders
SFGT for Persistent Anxiety and Depression
Rationale: Although there are effective treatments available for anxiety and depression, there is a large group of clients that does not benefit sufficiently from first-choice treatment.
- Conditions
- Depressive Symptoms, Anxiety Disorders, Persistent, Anxiety Depression
- Trial name
- NCT05942495
- Testing
- short-term schema focused group therapy
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- GGZ Noord-Holland-Noord
Major Depressive Disorder
Magnetic Resonance Imaging Study of Cognitive-Behavior Therapy for Major Depressive Disorder
Study hypothesis: psychotherapy and SSRI treatment effect in different brain way: psychotherapy in "up to down" way and SSRI in "down to up" way.
- Trial name
- NCT01460212
- Testing
- SSRI antidepressants, Cognitive-Behavior Therapy
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
Stroke, Quality of Life
Problem-Solving Therapy for Depressive Symptoms and Quality of Life in Stroke Survivor-Caregiver Dyads
The purpose of this feasibility study is to determine whether it is practical and helpful to provide problem-solving therapy to stroke survivors and their spouses/partners (caregivers) together.
- Conditions
- Stroke, Quality of Life, Depression
- Trial name
- NCT04035681
- Testing
- Problem-Solving Therapy, Stroke-Related Health Education
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Allina Health System
Pregnancy, Breastfeeding
The Effect of Early Versus Traditional Follow-Up on Breastfeeding Rates at 6 Months
The study's purpose is to determine if early (2-3 week) versus traditional (6-8 week) postpartum follow up is associated with a higher rate of breastfeeding at 6 months.
- Conditions
- Pregnancy, Breastfeeding, Contraception, Cervical Cancer
- Trial name
- NCT02221895
- Testing
- Postpartum follow up appointment 2-3 weeks after delivery, Postpartum follow up 6-8wk after delivery
- Where
- United States
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Depression - Major Depressive Disorder
Effectiveness of Behavioral Activation Group Therapy for Patients With Depression at the Community in Thanh Hoa
This study aimed to evaluate whether the 8-week BA group therapy delivered at commune health stations (CHSs) improves depressive symptom severity, psychological distress, behavioral activation, resilient coping, and…
- Trial name
- not yet (NCT07527312)
- Testing
- Behaviral activation group therapy
- Where
- Vietnam
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Hanoi Medical University
Food Insecurity, Dietary Quality
Enjoying Affordable and Tasty Food Together
The goal of this pilot study is to examine the feasibility of a novel meal kit and nutrition education intervention among adults aged 40 years and older, who are lower income, and to evaluate the preliminary impact of the meal…
- Conditions
- Food Insecurity, Dietary Quality, Quality of Life, Cooking Self-efficacy
- Trial name
- PROJECT EATT (NCT07036757)
- Testing
- Meal Kit and Nutrition Education
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Massachusetts, Lowell
Depression
Late-life Depression and Cerebral Perfusion
The long-term goal is to determine if decreased blood flow to the brain (cerebral hypoperfusion) is predictive of antidepressant outcomes in late-life depression (LLD).
- Trial name
- NCT01751828
- Testing
- Sertraline
- Where
- United States
- Sponsor
- Vanderbilt University
Major Depressive Disorder, Bi-Polar Disorder
DELPhI Evaluation of Psychiatric Conditions
DELPhI acquisition and analysis software, a QuantalX Neuroscience development, which is designed to measure, analyze, and display brain electrical activity of human electroencephalogram (EEG), to transcranial magnetic stimulation…
- Conditions
- Major Depressive Disorder, Bi-Polar Disorder, ADHD, Schizophrenia
- Trial name
- NCT03842345
- Sponsor
- QuantalX Neuroscience
Depressive Symptoms, Parkinson's Disease
Rasagiline in Cognitive-impairment Related Depression: AzileCt in COgnitive-impairment Related DepressiOn
The primary endpoint for this study is the clinical response after 12 weeks of treatment, defined as a change in total score from baseline depressive symptoms as measured by the Beck Depression Inventory-Amended (BDI-IA) total…
- Trial name
- ACCORDO (NCT01055379)
- Testing
- Rasagiline
- Where
- 12 sites in Italy
- Volunteers
- 121 people
- Sponsor
- Lundbeck Italia S.p.A.
Major Depressive Disorder
Efficacy and Safety Study of BHV-7000 Monotherapy in Major Depression
The purpose of this study is to determine the efficacy and safety of BHV-7000 in participants with Major Depressive Disorder (MDD)
- Trial name
- NCT06419608
- Testing
- BHV-7000
- Where
- 62 sites in United States
- Volunteers
- 336 people
- Sponsor
- Biohaven Therapeutics Ltd.
Pain, Post Partum Depression
Vaginal Postpartum Pain Management Protocol Comparison
Untreated postpartum pain has been associated with increased risk of opioid use, postpartum depression and development of persistent pain.
- Conditions
- Pain, Post Partum Depression, Opioid Use, Breast Feeding
- Trial name
- NCT04087317
- Testing
- Paracetamol 1000 Mg Oral Tablet, Ibuprofen 400Mg Tab, Ibuprofen 400 mg
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Rambam Health Care Campus
Depression, Bipolar Disorder
Predictors of Response to Augmentation With Ziprasidone (Geodon®) in Major Depressive Disorder
The primary outcome of this study is to determine if predictors of response can select a population of patients with MDD that is effectively treatable by augmentation with ziprasidone.
- Trial name
- NCT01168674
- Testing
- ziprasidone, Sugar pill
- Volunteers
- 49 people
- Sponsor
- Tufts Medical Center
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