Clinical trials: Depressive; Behavioral Disorder
Mental Disorder, Depressive Disorder
Effects of Psychoeducation of Relatives to Patients With Serious Mental Illness
The purpose of this study is to determine the effects of psychoeducation for relatives to patients with serious mental illness.
- Conditions
- Mental Disorder, Depressive Disorder, Schizophrenia
- Trial name
- NCT00184379
- Testing
- Psychoeducation
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Norwegian University of Science and Technology
Social Anxiety Disorder, Major Depressive Disorder
Vortioxetine Versus Placebo in Major Depressive Disorder Comorbid With Social Anxiety Disorder
This placebo-controlled study is designed to determine the efficacy, safety, and tolerability of vortioxetine in the treatment of adults with Major Depressive Disorder (MDD) that is comorbid with Social Anxiety Disorder (SAD).
- Trial name
- NCT02294305
- Testing
- Vortioxetine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The Medical Research Network
Depressive Symptoms, Anxiety Disorders
Messaging Therapy for Depression and Anxiety: A Longitudinal Effectiveness Study
Therapies delivered via technology have been developed to improve accessibility, however, there is limited research regarding messaging therapy in particular, and none that we know of utilizing a longitudinal effectiveness…
- Trial name
- NCT03699488
- Testing
- psychotherapy via asynchronous message
- Volunteers
- 12,980 people
- Sponsor
- Talkspace
Depression
Emotional and Cognitive Control in Late-Onset Depression
This study may help identify how abnormalities in brain systems that control the ability to ignore irrelevant information may contribute to the development of depression in older adults.
- Trial name
- NCT01728194
- Testing
- Escitalopram, Magnetic Resonance Imaging
- Where
- 2 sites in United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Depressive Disorder, Treatment-Resistant
rTMS With and Without iCBT For the Treatment of Resistant Depression (TRD)
This is a prospective, two-arm randomized controlled trial. 100 patients diagnosed with resistant depression in psychiatric care clinic in Edmonton, Alberta, Canada will be randomized to one of two conditions: (1) enrolment in…
- Trial name
- NCT04239651
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Internet-Delivered Cognitive Behavior Therapy (iCBT)
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of Alberta
Bipolar Disorder, Mood Disorders
Characterizing MyMood Patterns of Use
MyMood is an electronic mood-charting tool available to the general population of Sunnybrook Health Sciences Centre (SHSC). This project aims to characterize duration and frequency of use of MyMood by users characteristics and…
- Conditions
- Bipolar Disorder, Mood Disorders, Depression, Dysthymia
- Trial name
- NCT04664374
- Testing
- MyMood
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- Sunnybrook Health Sciences Centre
Medication Adherence, Depressive Symptoms
Testing THRIVE 365 for Black Sexual Minority Men (On The Daily)
The primary goal of this study is to test a minority stress model of psychological health outcomes for Black sexual minority men (BSMM) while using and not using a novel intervention named THRIVE 365.
- Conditions
- Medication Adherence, Depressive Symptoms, Anxiety Symptoms, Emotion Regulation
- Trial name
- OTD (NCT05376397)
- Testing
- iTHRIVE 365
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Major Depression
Efficacy of 18-Months of Antidepressive Medication Plus CBT or Dynamic or Supportive Psychotherapy for Recurrent Major Depression
Major Depressive Disorder affects approximately 16% of the adult population over the lifetime. Controlled studies indicate that short-term antidepressive medications or psychotherapy produce full remission in only about 46% of…
- Trial name
- NCT00220623
- Testing
- antidepressant medications, flexible drug choice, CBT, Psychodynamic or Supportive Psychotherapy
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Treatment Resistant Depression (TRD)
Risk-Targeted Behavioural Activation for the Management of Treatment-Resistant Depression.
Depression is the leading cause of disability worldwide. Major Depressive Disorder (MDD) is the most common diagnosis made for individuals seeking treatment for depression.
- Trial name
- NCT06729580
- Testing
- Behavioural Activation
- Where
- Canada
- Volunteers
- 118 people
- Sponsor
- McGill University
Bipolar Affective Disorder, Depression
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder
This study will examine whether mitochondrial function is impaired in patients with bipolar disorder. Mitrochondria are small organelles inside the cell that are responsible for energy production.
- Trial name
- NCT00327756
- Testing
- Coenzyme Q10
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Depression
B Vitamins in MTHFR Positive Patients With Major Depression: A Post Hoc Analysis of Findings
A randomized double-blind placebo controlled study of reduced B vitamins in patients with major depression who were positive for one or both of the common MTHFR polymorphisms was conducted between 8/1/2014 and 4/3/2015.
- Trial name
- BVMD (NCT02709668)
- Testing
- Enlyte
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- High Point Regional Health Systems
Depression - Major Depressive Disorder, Anxiety Disorders
AI-Guided CBT for Depression and Anxiety
This study aims to evaluate the effectiveness of an artificial intelligence (AI)-guided cognitive behavioral therapy (CBT) program for the treatment of mild depression and anxiety disorders in adults.
- Trial name
- AI-CBT-DA (NCT07576686)
- Testing
- AI-Guided Cognitive Behavioral Therapy, Cognitive Behavioral Therapy (CBT)
- Where
- Serbia
- Volunteers
- 120 people
- Sponsor
- Aleksandra Stojanovic
Fibromyalgia, Depressive Symptoms
Psychological Treatment of Depression in Women With Fibromyalgia
The purpose of this study is to perform an efficacy study of Personal Construct Therapy, which focuses on the construction of self and others, for women diagnosed with fibromyalgia who have also comorbid depressive symptoms.
- Trial name
- PCTFORDEPFM (NCT02711020)
- Testing
- Cognitive Behavioral Therapy, Personal Construct Therapy
- Where
- 4 sites in Spain
- Volunteers
- 110 people
- Sponsor
- University of Barcelona
Depressive Symptoms, Emotional Depression
Parenting-STAIR Modular for Military Fathers and OCONUS Families
The goal of this clinical trial is to learn if a family-based treatment called Parenting-STAIR-Modular (PSTAIR-M) can help military parents recover from trauma, strengthen emotion regulation skills, and improve parent-child…
- Conditions
- Depressive Symptoms, Emotional Depression, Depression, Parent Child Relationship
- Trial name
- NCT07843654
- Testing
- Parenting-STAIR Modular (PSTAIR-M), Treatment as Usual (TAU)
- Where
- 6 sites in United States, South Korea
- Volunteers
- 243 people
- Sponsor
- New York University
Depression, Depressive Disorder
Effects of Behavioural Activation on Emotional Cognition and Mood
Behavioural activation (BA) is widely accepted as an efficacious treatment for depression. It has been suggested that several depression treatments work via early changes in emotional processing (e.g.
- Conditions
- Depression, Depressive Disorder, Mood Disorders, Cognition
- Trial name
- NCT03995186
- Testing
- Behavioural activation, Activity monitoring
- Where
- United Kingdom
- Volunteers
- 97 people
- Sponsor
- University of Oxford
Major Depressive Disorder, Treatment Resistant
Nuedexta in Treatment-Resistant Major Depression
There is an urgent need, therefore, to identify well-tolerated, orally available compounds that target the NMDA receptor as a novel treatment approach for TRD.
- Trial name
- NCT01882829
- Testing
- dextromethorphan/quinidine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- James Murrough
Preterm Birth, Cervical Insufficiency
Bed Rest With a Short Cervix on Preterm Birth
Maternal AR has long been used to prevent PTB. However, definitions of AR vary widely, ranging from complete bed rest to partial limitation of physical activity for one or more hours daily.
- Conditions
- Preterm Birth, Cervical Insufficiency, Bed Rest, Pregnancy Complications
- Trial name
- BEWISE (NCT07577388)
- Testing
- Activity Restriction, No Activity Restriction
- Volunteers
- 6,000 people
- Sponsor
- Julie Glavind
Dementia, Agitation
A Music-Based Mobile App for People Living With Alzheimer's Disease and Related Dementias (ADRD)
The purpose of this pilot is to develop a mobile application that detects physiological measures of individuals with Alzheimer's disease and related dementias and triggers auto-play of personalized songs in a wearable device.
- Conditions
- Dementia, Agitation, Depressive Symptoms
- Trial name
- NCT06140342
- Testing
- Feasibility study of music-based mobile app
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Autotune Me LLC
Anxiety Disorders, Depressive Disorder
Testing Psychosocial Treatment Planning Methods for Youth Anxiety and Depression
Youth depression and anxiety represent a serious public health concern, with affected youth often experiencing social, familial, and academic impairment.
- Trial name
- NCT03610373
- Testing
- Modular Approach to Therapy for Children (MATCH)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Boston University Charles River Campus
Lung Cancer
Sleep and Immune Checkpoint Inhibitors
Sleep disturbances are prevalent in cancer patients and linked to levels of fatigue and depressive symptoms with a major impact on quality of life.
- Trial name
- NCT04070651
- Where
- Denmark
- Volunteers
- 49 people
- Sponsor
- Aarhus University Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.