Clinical trials: Depressive; Behavioral Disorder
Unipolar Depression
Repetitive Transcranial Magnetic Stimulation and Venlafaxine in Depression
The purpose of this study is to assess the efficacy of add-on therapy with repetitive Transcranial Magnetic Stimulation (rTMS) and venlafaxine in the treatment of major depressive disorders compared to venlafaxine only (the…
- Trial name
- NCT00714090
- Testing
- active venlafaxine and active rTMS-repetitive transcranial magnetic stimulator, Inomed and Alpine Biomed
- Where
- 18 sites in France, Monaco
- Volunteers
- 170 people
- Sponsor
- Club rTMS et Psychiatrie
Depression
Intravenous Ketamine Effects on Functional Neuroanatomy
The purpose of this study is to investigate the neuroanatomical effects of ketamine treatment on patients with treatment-resistant depression.
- Trial name
- NCT04205890
- Testing
- Ketamine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Neurological Associates of West Los Angeles
Major Depression
Multicenter Comparative Study of the Activity of the Medial Prefrontal Cortex in Vulnerability to Depression
To examine whether the medial prefrontal cortex displays an increased activity during self-referential processing among remitted depressed patients compared to healthy controls
- Trial name
- CORVAD (NCT02171923)
- Where
- France
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Major Depression, Pregnancy
RCT of At-Home tDCS for Depression in Pregnancy
This is a randomized, sham-controlled trial to determine whether treatment with transcranial direct current stimulation (tDCS) is superior to a sham condition at reducing the symptoms of depression in pregnant people with…
- Conditions
- Major Depression, Pregnancy, Postpartum Depression
- Trial name
- NCT05097586
- Testing
- active tDCS, workbook
- Where
- 2 sites in Canada
- Volunteers
- 156 people
- Sponsor
- Women's College Hospital
Depression, Dysthymic Disorder
Duloxetine Treatment in Elderly With Dysthymia
Dysthymic disorder (DD) denotes chronic depression with fewer symptoms than major depressive disorder (MDD), and it affects ~ 2-4 % of adults with a similar prevalence in the elderly.
- Trial name
- NCT01852383
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- New York State Psychiatric Institute
Depression
Using Functional MRI Neurofeedback to Modulate Self-blame in Major Depressive Disorder
To determine the feasibility of functional MRI neurofeedback in reducing overgeneralised self-blame in patients with depression
- Trial name
- NCT05455827
- Testing
- fMRI neurofeedback (A), fMRI neurofeedback (B)
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Brighton & Sussex Medical School
Depression, Depressive Disorder
Research Evaluating the Value of Augmenting Medication With Psychotherapy
This 24-week study, with a 12-month follow up period, will compare the effectiveness of antidepressant medication alone to the combination of psychotherapy and antidepressant medication in patients with chronic depression.
- Trial name
- REVAMP (NCT00057551)
- Testing
- Brief Supportive Psychotherapy, CBASP, Medication Only
- Where
- 8 sites in United States
- Volunteers
- 491 people
- Sponsor
- Weill Medical College of Cornell University
Depression, Anhedonia
Dimensional Approach to Evaluate Reward Processing in Major Depressive Disorder Pre- and Post-Desvenlafaxine Treatment
Anhedonia (the lack of pleasure in normally pleasurable things) is a common symptom of major depressive disorder (MDD), and it may impact how patients with depression experience reward.
- Trial name
- NCT02859103
- Testing
- Desvenlafaxine
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Depressive Disorders, Psychotic Disorders
Safety of Org 34517 900 mg in Patients Who Received Org 34517 in a Previous Trial (Study 28133/P05842)
Patients who participated in the previous trial 28130, who were eligible, were entered into this trial. Patients who were randomized to placebo in the previous trial 28130 continued on placebo while patients who were randomized…
- Conditions
- Depressive Disorders, Psychotic Disorders, Depression
- Trial name
- NCT00844922
- Testing
- SCH 900636
- Volunteers
- 16 people
- Sponsor
- Merck Sharp & Dohme LLC
Depression, Major Depressive Disorder
Novel Neural Circuit Biomarkers of Major Depression Response to CCBT
The purpose of the study is to learn more about computer-assisted cognitive behavioral therapy or "CCBT" and to examine connections in the brains of patients with depression.
- Conditions
- Depression, Major Depressive Disorder, Depressive Disorder, Depression, Unipolar
- Trial name
- NCT03096886
- Testing
- Computer-Augmented Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Depression
Efficacy of Narrative Therapy for Older People With Depression
The research aims to investigate the efficacy of a narrative therapy group in reducing depressive symptoms among older people. This study adopts a mixed methods research design, involving both quantitative and qualitative…
- Trial name
- NTOPD (NCT07371988)
- Testing
- Narrative therapy group, Treatment as usual (TAU)
- Where
- Hong Kong
- Volunteers
- 110 people
- Sponsor
- City University of Hong Kong
Depressive Symptoms, Anxiety
Caring for Family Caregivers:a Research-action Study
The purpose of this study is to evaluate the effectiveness of the Problem Solving Technique (PST) in reducing symptoms of anxiety and depression among primary caregivers of chronically ill patients.
- Conditions
- Depressive Symptoms, Anxiety, Emotions
- Trial name
- NCT01786083
- Testing
- Application of Problem Solving Technique
- Where
- Spain
- Volunteers
- 122 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Parkinson Disease, Parkinson Disease 10
Video Dance Class and Unsupervised Physical Activity During Covid-19 Pandemic in People With Parkinson's Disease
The aim of this study is to analyze the impact of video dance class and unsupervised physical activity on clinical-functional parameters, self-isolation and non-motors symptoms in people with Parkinson's disease during the…
- Trial name
- PTT-Online (NCT04422353)
- Testing
- Video Dance classes, Unsupervised physical activities
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of Rio Grande do Sul
Stroke, Insomnia
Instant Message-delivered Cognitive Behavioural Therapy for Insomnia (CBT-I)Stroke Caregivers
The proposed trial aims to assess the effectiveness of Cognitive-behavioural therapy for insomnia (CBT-I) based ecological momentary intervention (EMI) for reducing insomnia symptoms among stroke caregivers.
- Conditions
- Stroke, Insomnia, Depressive Symptoms, Caregiver Burnout
- Trial name
- NCT05952245
- Testing
- iCBTI-based EMI, Education-based EMI
- Where
- 5 sites in Hong Kong
- Volunteers
- 138 people
- Sponsor
- The University of Hong Kong
Depression
Functional Outcome in Postpartum Depression in Women Treated With Desvenlafaxine
Postpartum depressed women suffer from functional impairment in their mood, thoughts, cognition and physical well being leading to poor motivation, bonding difficulties, decreased productivity, conflict and neglect.
- Trial name
- NCT01527786
- Testing
- Desvenlafaxine
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- BC Women's Hospital & Health Centre
Depressive Symptoms, Anxiety Disorders
SFGT for Persistent Anxiety and Depression
Rationale: Although there are effective treatments available for anxiety and depression, there is a large group of clients that does not benefit sufficiently from first-choice treatment.
- Conditions
- Depressive Symptoms, Anxiety Disorders, Persistent, Anxiety Depression
- Trial name
- NCT05942495
- Testing
- short-term schema focused group therapy
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- GGZ Noord-Holland-Noord
Post Partum Depression
Risk of Maternal Depression From 1 Year to 4 Years Postpartum in Yvelines
This observational study aims to estimate the prevalence of women from 1 to 4 years postpartum in Yvelines, who are suspected to suffer from postpartum depression, using the Edinburg Post natal Depression Scale (EPDS) and the…
- Trial name
- DeTaPoP (NCT06042972)
- Testing
- Questionnaire including Edinburgh postnatal depression scale, Patient Health Questionnaire 2 and background variables
- Where
- France
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Centre Médical Porte Verte
Depression
Paroxetine/Bupropion in Suicide Attempters/Ideators With Major Depression
The primary study comparing effectiveness for suicidal ideation and/or behavior of two antidepressant medications in depressed patients who have attempted suicide or are currently experiencing suicidal thoughts has been…
- Trial name
- NCT00429169
- Testing
- Paroxetine, Bupropion
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- New York State Psychiatric Institute
Major Depressive Disorder, Depression
Precision Care for Major Depressive Disorder
This study aims to assess whether phenotyping-guided intervention selection is superior to intervention selection without phenotyping guidance (i.e., routine clinician and patient judgment regarding treatment selection) for…
- Conditions
- Major Depressive Disorder, Depression, Depressive Disorder, Major
- Trial name
- NCT06580041
- Testing
- Pramipexole, Methylphenidate, Phenelzine
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of California, San Francisco
Depressive Symptoms, Anxiety States, Neurotic
Using the PHQ-9 and GAD-7 as Feedback Instruments in Brief Psychotherapy
This study will assess the effects of client feedback, using the Patient Health Questionnaire - 9 and Generalized Anxiety Disorder 7-Item Scale, on depression and anxiety in individuals undergoing brief psychotherapy.
- Trial name
- NCT02656641
- Testing
- Continuous Client Feedback, Continuous Self Feedback
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Christiana Care Health Services
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