Clinical trials: Depressive; Behavioral Disorder
Chronic Obstructive Pulmonary Disease, Depression
The Effect on Depressive Symptoms in ECF Residents With COPD
The purpose of this study is to assess the effect of treatment with Advair Diskus on depression using the Cornell depression scale in COPD patients in the nursing home.
- Trial name
- DISK-02 (NCT00974246)
- Testing
- Advair diskus
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Valley Medical Research
Cardiac Failure, Heart Failure
Insomnia Self-Management in Heart Failure
Chronic insomnia may contribute to the development and exacerbation of heart failure (HF), incident mortality and contributes to common and disabling symptoms (fatigue, dyspnea, anxiety, depression, excessive daytime sleepiness…
- Conditions
- Cardiac Failure, Heart Failure, Congestive Heart Failure, Heart Failure, Congestive
- Trial name
- HSS (NCT02660385)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Self-Management Education for Heart Failure
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Yale University
Healthy, Involutional Depression
Bone Mineral Density in Women With Major Depression
The purpose of this study is to examine calcium absorption and bone mineral density in women with depression. Research indicates that pre-menopausal women with depression have significantly lower bone mineral density (BMD) than…
- Conditions
- Healthy, Involutional Depression, Osteoporosis
- Trial name
- NCT00001413
- Where
- United States
- Volunteers
- 585 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Dementia
VRx@Home: Study to Evaluate VR-therapy for PwD Living at Home
The investigators are designing and rigorously evaluating the first Virtual Reality-therapy program for people with dementia (PwD) living at home, administered by their informal caregivers (family/friends).
- Trial name
- VRx@Home (NCT04988360)
- Testing
- HMD: Immersive VR, Tablet: Non-immersive VR
- Where
- 2 sites in Canada
- Volunteers
- 7 people
- Sponsor
- University Health Network, Toronto
Major Depressive Disorder
Cysteamine Therapy for Major Depressive Disorder
The purpose of this study is to determine whether cysteamine bitartrate, an FDA-approved drug for a non-psychiatric condition, is safe and effective for the treatment of major depression.
- Trial name
- NCT00715559
- Testing
- cysteamine bitartrate
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Major Depressive Disorder
FMRI Study of Performance During a Probabilistic Reversal Learning Task in Depression
This study will examine how the brains of depressed people function during learning and respond to feedback. Participants perform a "probabilistic reversal learning task" to determine whether depressed people perform worse on a…
- Trial name
- NCT00075296
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Schizophrenia, Bipolar Disorder
Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental Illness
Many individuals with serious mental illness have difficulty accurately interpreting interpersonal cues and effectively engaging in social exchanges.
- Conditions
- Schizophrenia, Bipolar Disorder, Depressive Disorder, Major, Stress Disorder, Post-Traumatic
- Trial name
- NCT05491538
- Testing
- Social Cognition and Interaction Training-Work Edition (SCIT-WE)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Depression, Major Depressive Disorder
Study of Naltrexone-Induced Blockade of Antidepressant Effects
The goal of this study is to determine whether antidepressant placebo effects and contextual cues broadly, can be blocked by one single dose of the µ-opioid antagonist naltrexone.
- Trial name
- SONRISA2 (NCT04322526)
- Testing
- Naltrexone 50 Mg Oral Tablet
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Marta Peciña, MD PhD
High-risk Pregnancy, Hospitalization
LLM-Generated Medical Summaries During Hospitalization to Improve Patient Activation in High-Risk Pregnancies
The goal of this clinical trial is to learn if AI-generated medical summaries help hospitalized pregnant participants better understand and actively participate in their own care.
- Conditions
- High-risk Pregnancy, Hospitalization, Patient Activation, Artificial Intelligence (AI)
- Trial name
- NCT07823517
- Testing
- LLM-Generated Medical Summaries
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Sheba Medical Center
Unipolar Depression
The Effects of Sleep Deprivation on Antidepressant Response
This study will use positron emission tomography (PET) to examine the effect of sleep deprivation on brain function.
- Trial name
- NCT00178074
- Testing
- total sleep deprivation, PET imaging
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Depression - Major Depressive Disorder, Psilocybin
Group PACBT for Depression
This study will seek to determine the (1) acceptability and (2) feasibility of psilocybin as an adjunct to cognitive-behavioral therapy, delivered as a group treatment (G-PACBT) for major depressive disorder and (3) explore the…
- Conditions
- Depression - Major Depressive Disorder, Psilocybin, Cognitive Behavioral Therapy
- Trial name
- NCT07566104
- Testing
- Psilocybin (drug), Group Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Los Angeles
Post-partum Depression
Virtual Patient Navigation During a Pandemic
The sub-study will involve a rigorous mixed-methods design. The qualitative phase of the sub-study will consist of semi-structured interviews.
- Trial name
- NCT06208852
- Testing
- Virtual Navigator Program
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Depression
Antepartum Study on Use of Interpersonal Psychotherapy at 3 New York City Site
This study will evaluate the effectiveness of interpersonal psychotherapy in treating pregnant women with depression.
- Trial name
- NCT00251043
- Testing
- Interpersonal psychotherapy for depression in pregnancy, Parenting education program (PEP)
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
COPD, Anxiety State
Assessment of Stress Levels and Depressive and Anxiety Symptoms in Patients With COPD
The aim of the study was to assess the levels of depression, anxiety and stress in patients with COPD qualified for In-hospital pulmonary rehabilitation program
- Conditions
- COPD, Anxiety State, Stress, Depressive Symptoms
- Trial name
- NCT04726917
- Testing
- Pulmonary rehabilitation
- Where
- Poland
- Volunteers
- 51 people
- Sponsor
- The Opole University of Technology
Depression
The Efficacy and Safety of tDCS in Patients With Mild to Moderate Major Depressive Disorder
This study evaluated the effectiveness and safety of improving depressive symptoms by applying tDCS for 6 weeks to patients with mild to moderate depression.
- Trial name
- NCT04720040
- Testing
- Mind STIM
- Where
- South Korea
- Volunteers
- 65 people
- Sponsor
- Ybrain Inc.
Depression, Depressive Disorder
The Oh Happy Day Class - Digital Connections (OHDC-DC): A Pilot Study
The goal of this clinical trial is to see if a mobile phone app can deliver depression treatment to African Americans who are depressed.
- Conditions
- Depression, Depressive Disorder, Depressive Symptoms
- Trial name
- OHDC-DC (NCT06206226)
- Testing
- OHDC-DC
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Wisconsin, Madison
Insomnia Chronic
Treatment of Insomnia in Primary Care Study
The goal of this clinical trial is to learn about insomnia treatment among primary care patients with chronic insomnia. The main question it aims to answer is: Does Sleep School (a therapy for insomnia) work well to decrease harm…
- Trial name
- TIP (NCT06149273)
- Testing
- Sleep School, Treatment as usual
- Where
- Finland
- Volunteers
- 250 people
- Sponsor
- University of Turku
Depression, Mood Disorders
Functional MRI Before and After Treatment for Depression
The purpose of this study is to help us understand how depression changes brain activity and how this relates to mood, anxiety, and cognitive functions like memory.
- Conditions
- Depression, Mood Disorders, Depressive Disorder
- Trial name
- NCT00896441
- Testing
- Citalopram
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Stanford University
Major Depressive Disorder
Microdosing Psychedelics to Improve Mood
This trial aims to examine the safety and efficacy of small (2mg) sub-hallucinogenic doses of psilocybin in people with Major Depressive Disorder.
- Trial name
- NCT05259943
- Testing
- Psilocybin first
- Where
- Canada
- Volunteers
- 39 people
- Sponsor
- Rotem Petranker
Depression, Depressive Disorder
Comparison Study of the Different Abbreviated Versions of the Geriatric Depression Scale
This multicenter study conducted in several Portuguese institutions aims to compare the screening ability of the several Geriatric Depression Scale (GDS) validated versions for the Portuguese population (GDS-30, GDS-15, GDS-10…
- Conditions
- Depression, Depressive Disorder, Neurocognitive Disorders, Dementia
- Trial name
- NCT04180683
- Testing
- Battery of screening tests with semi-structured interview, Battery of screening tests without semi-structured interview
- Where
- 32 sites in Portugal
- Volunteers
- 331 people
- Sponsor
- Rsocialform - Geriatria, Lda
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