Clinical trials: Depressive Disorder, completed
Pregnancy, Depression
PDA for Antidepressant Use in Pregnancy
Depression in pregnancy is common, affecting up to 10% of women and represents serious risk to mother and infant. Unfortunately, antidepressant medication, a first-line treatment for depression in pregnancy, also comes with…
- Trial name
- NCT03632863
- Testing
- Electronic Patient Decision Aid, Standard Resource Sheet
- Where
- Canada
- Volunteers
- 462 people
- Sponsor
- Women's College Hospital
Major Depressive Episode
Retrospective Observational Study DIANA Study
This Non-Interventional Study (NIS) is intended to evaluate the duration of treatment with an initial antidepressant taken as monotherapy in patients in whom treatment was changed because of suboptimal response at physician's…
- Trial name
- DIANA (NCT01976793)
- Where
- 8 sites in Russia
- Volunteers
- 450 people
- Sponsor
- AstraZeneca
Depression
PACEPro - Mood Management Pilot
Researchers at the University of California at San Diego (UCSD) are conducting a 12-week study to test the PACEPRO program. This program is designed to reduce depression by providing: Lexapro, an antidepressant medicine…Learn…
- Trial name
- NCT00416221
- Testing
- Lexapro, an antidepressant medicine, Physical Activity, Mood Management Skills
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Diego
Depression
Omega 3 for Treatment of Depression in Patients With Heart Failure
Omega 3 supplements will improve depressive symptoms to a greater extent than placebo in heart failure patients with moderate to severe major depressive disorder.
- Trial name
- OCEAN (NCT02057406)
- Testing
- 2:1 EPA/DHA, High EPA
- Where
- 3 sites in United States
- Volunteers
- 108 people
- Sponsor
- Wei Jiang
Emotional Disorders, Anxiety Disorders
A Unified Treatment for Anxiety Disorders
The purpose of this study is to develop a new psychological therapy for a variety of different types of emotional disorders. The study will compare symptoms and functioning of clients who receive the treatment with those who do…
- Trial name
- NCT00586001
- Testing
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Volunteers
- 37 people
- Sponsor
- Boston University Charles River Campus
Depressive Disorder, Major
Outcomes in MEasurement-Based Treatment
The primary objective for this study is to assess the impact of a measurement based treatment program (MBT) on Major Depressive Disorder (MDD) remission rates in patients whose primary care provider (PCP) receives monthly…
- Trial name
- COMET (NCT01141387)
- Volunteers
- 914 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Type 1 Diabetes Mellitus, Covid19
Evaluation of Quality of Life in Patients With Type 1 Diabetes Mellitus During the Covid-19 Pandemic
During the COVID-19 pandemic, the time spent at the home of patients has increased because of national quarantine policies and patients' fear of getting sick.
- Trial name
- NCT04558645
- Testing
- Online Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Gazi University
Anxiety, Depression
Attention Bias Modification Training for Young People
Attention bias modification training (ABMT) is a computer-based attention training programme designed to modify the way a person's attention is directed to mild threats in the environment.
- Trial name
- NCT02270671
- Testing
- ABMT
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Depression
Strong Connections
The purpose of this study is to compare two talking forms of therapy designed to help reduce depressive symptoms in teenagers: Interpersonal Psychotherapy for Adolescents and Treatment as Usual.
- Trial name
- NCT03308864
- Testing
- Interpersonal Psychotherapy for Adolescents, Treatment as usual
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Rochester
Major Depressive Disorder
Vagus Nerve Stimulation: Integration of Behavior and Cardiac Modulation
This study characterized the impact of respiratory-gated transcutaneous vagus nerve stimulation (tVNS) on the modulation of the stress response circuitry, vagal tone and depressed mood in patients with major depressive disorder…
- Trial name
- tVNS-MDD (NCT04467164)
- Testing
- exhalatory-gated transcutaneous vagus nerve stimulation (e-RAVANS), Inhalatory-gated transcutaneous vagus nerve stimulation (i-RAVANS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Anxiety, Depression
Sudarshan Kriya Yoga and Cardiac Autonomic Control in Patients With Anxiety-Depression Disorders
The effects of Sudarshan Kriya Yoga (SKY) on autonomic function in patients with anxiety-depression disorders is unknown. Thus, the authors will investigate cardiac autonomic control in a population of patients with…
- Trial name
- NCT02828072
- Testing
- SKY therapy, usual drug therapy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Milan
Major Depressive Disorder
Duloxetine Versus Paroxetine for Major Depression
To determine if duloxetine works just as well as paroxetine in the treatment of major depressive disorder.
- Trial name
- NCT00489775
- Testing
- Duloxetine, Paroxetine
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Eli Lilly and Company
Depression, Anxiety Disorders
Effects of Interpersonal Psychotherapy on Depression During and After Pregnancy
This study will evaluate the impact of interpersonal psychotherapy on the course of depression during and after pregnancy, as well as its effect on infant birth outcomes.
- Trial name
- NCT00380419
- Testing
- Interpersonal Psychotherapy (IPT)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Michigan
Major Depressive Disorder
Predictors of Treatment Outcome With Cognitive Behavioral Therapy for Depression
The purpose of this research study is to learn whether specific types of brain imaging and psychological testing can predict how much benefit patients with depression will receive from a well-studied psychotherapy for depression…
- Trial name
- NCT01922219
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Major Depression
Cognitive Behavioral Treatments for Depression in Chronic Illness
Duke University Medical Center in collaboration with Glendale Adventist Medical Center propose a randomized clinical trial of conventional cognitive behavior therapy (CCBT) vs.
- Trial name
- NCT01208428
- Testing
- Conventional cognitive behavioral therapy, Religious cognitive behavioral therapy
- Where
- 2 sites in United States
- Volunteers
- 132 people
- Sponsor
- Duke University
Depressive Disorder
Omega-3 Fatty Acids for Major Depressive Disorder During Pregnancy
Whether high-dose omega-3 fatty acids supplement would be an effective treatment in patients with major depressive disorder during pregnancy and breast-feeding.
- Trial name
- NCT00618865
- Testing
- Omega-3 fatty acids
- Volunteers
- 36 people
- Sponsor
- National Science and Technology Council, Taiwan
Depression, Parkinson's Disease
Efficacy of Psychotherapy for Depressed Parkinson's Disease Patients
The primary aim of this randomized controlled trial is to determine the acute antidepressant efficacy of interpersonal psychotherapy (IPT) in depressed patients with Parkinson's Disease.
- Trial name
- NCT02552836
- Testing
- Interpersonal Psychotherapy, Supportive Psychotherapy
- Where
- 2 sites in Canada
- Volunteers
- 63 people
- Sponsor
- Hopital Montfort
Diabetes, Depression
INtegrating DEPrEssioN and Diabetes treatmENT (INDEPENDENT) Study
To provide better care and preventive services for people with both depression and diabetes, the investigators propose to develop and test whether interventions to reduce depressive symptoms can be integrated into routine…
- Conditions
- Diabetes, Depression, Cardiovascular Risk Factor
- Trial name
- INDEPENDENT (NCT02022111)
- Testing
- Patient Education and Behavioral Activation, Supporting Self-Care (care coordinators), Psychiatrist and Diabetologist Reviews
- Where
- 4 sites in India
- Volunteers
- 404 people
- Sponsor
- Emory University
Depressive Disorder, Major
A Study of Adjunctive Treatment to Antidepressant Therapy for Adults With Major Depressive Disorder
The primary purpose is to study the efficacy, safety, and tolerability of LY2216684 as an adjunctive treatment for participants with major depressive disorder (MDD), who were identified as partial responders to an adequate course…
- Trial name
- NCT00840034
- Testing
- LY2216684
- Where
- 24 sites in United States
- Volunteers
- 227 people
- Sponsor
- Eli Lilly and Company
Depressive Disorder, Major
The Effect of Patient Cost-Sharing on Antidepressant and Adjunctive Therapy Use
The primary objective of this study is to measure the effects of patient cost-sharing on the initiation of adjunctive treatment and subsequent healthcare utilization and expenditures among a population of commercially insured…
- Trial name
- NCT01141400
- Volunteers
- 48,865 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.