Clinical trials: Depressive Disorder and Anxiety Disorders
Depression, Generalized Anxiety
The Mental Health Status of the General Population During the COVID-19 Pandemic and Its Association With Adherence to Government-initiated Non-pharmacological Epidemiological Interventions (NPI's)
This study seeks to investigate the levels of common psychopathology symptoms (i.e., depression and generalized anxiety) in a general population during the strict social distancing government-initiated non-pharmacological…
- Conditions
- Depression, Generalized Anxiety, Adherence to Non-pharmacological Epidemiological Interventions (NPIs)
- Trial name
- NCT04356365
- Testing
- Cross-sectional study investigating the association of NPIs with mental health
- Where
- Norway
- Volunteers
- 10,084 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Treatment Resistant Depression, Generalized Anxiety Disorder
An Open Label Study of Clinical Utility and Patient Outcomes of the Genecept Assay
Genomind has developed and introduced a battery of genetic tests, the Genecept Assay, which clinicians can administer to patients using a simple saliva sample technique. The present study proposes to enroll 1.
- Trial name
- COM-1 (NCT01507155)
- Testing
- Genecept Assay
- Where
- United States
- Volunteers
- 685 people
- Sponsor
- Genomind, LLC
Anxiety Disorders and Symptoms, Depressive Symptoms
Indicated Prevention Transdiagnostic Intervention for Adolescents At High Risk of Emotional Problems
Emotional disorders (anxiety and/or depression) are severely undiagnosed and untreated despite being among the most common mental disorders, particularly at a young age.
- Trial name
- PROCARE-I (NCT05252026)
- Testing
- PROCARE-I (UP-A for indicated purposes), Active control condition
- Where
- 3 sites in Spain
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Jaén
Anxiety Disorder, Breast Cancer
Gabapentin For the Control of Hot Flashes in Women With Breast Cancer
RATIONALE: Gabapentin may be effective for the control of hot flashes. It is not yet known if gabapentin is effective in treating hot flashes.
- Conditions
- Anxiety Disorder, Breast Cancer, Depression, Hot Flashes
- Trial name
- NCT00022074
- Testing
- gabapentin, quality-of-life assessment
- Where
- 18 sites in United States
- Sponsor
- Gary Morrow
Anxiety Depression (Mild or Not Persistent)
Life Satisfaction and Psychopathology in Institutionalized Elderly People
The present study attempted to test the benefits of a Mindfulness-Based Stress Reduction (MBSR) program in Portuguese institutionalized elderly people, as a way to improve life satisfaction and reduce psychopathology.
- Trial name
- NCT02774018
- Testing
- Mindfulness-Based Stress Reduction (MBSR) program
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Irmandade da Misericórdia de Albergaria-a-Velha
Functional Dyspepsia, Probiotics
Efficacy of Clostridium Butyricum in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia
Objective: This study aims to evaluate the effectiveness of Clostridium butyricum in improving anxiety and depression in patients diagnosed with functional dyspepsia according to the Rome IV criteria.
- Conditions
- Functional Dyspepsia, Probiotics, Depression, Anxiety
- Trial name
- NCT07182890
- Testing
- Clostridium butyricum
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Trauma, Anxiety
The Ukrainian Student Problem Solving Project
The purpose of this study is to test the effectiveness of a universal, digital, single-session intervention for youth mental health, functioning, and well-being.
- Conditions
- Trauma, Anxiety, Depression, Child Behavior
- Trial name
- NCT06064578
- Testing
- Project SOLVE
- Where
- United States
- Volunteers
- 778 people, healthy volunteers welcome
- Sponsor
- Harvard University
Breast Cancer, Chronic Pain
Evaluation And Risk Assessment For Persistent Postsurgical Pain After Breast Surgery
Pre-existing pain and severe postoperative pain are predictors of persistent pain after surgery, but a complete understanding on the development of persistent pain is still lacking.
- Conditions
- Breast Cancer, Chronic Pain, Acute Pain, Depression, Anxiety
- Trial name
- B-CAPP (NCT03408717)
- Testing
- Questionnaires, Mechanical Temporal Summation assessment, Pain threshold assessment
- Where
- 2 sites in United States, Singapore
- Volunteers
- 220 people
- Sponsor
- KK Women's and Children's Hospital
Anxiety, Depression
Brief CBT for Anxiety and Advanced Cancer
RATIONALE: Providing cognitive-behavioral therapy (CBT) may reduce anxiety and improve quality of life of patients with advanced cancer.
- Conditions
- Anxiety, Depression, Unspecified Adult Solid Tumor, Protocol Specific, Cancer
- Trial name
- NCT00706290
- Testing
- Brief Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Massachusetts General Hospital
Erectile Disfunction, Coronary Artery Disease (CAD)
"Erectile Function After PCI in MI and Non-MI Patients"
The goal of this observational study is to assess changes in patients' erectile function after percutaneous coronary intervention (PCI) using a standard IIEF (International Index of Erectile Function) questionnaire at 1, 3, and 6…
- Conditions
- Erectile Disfunction, Coronary Artery Disease (CAD), Diabete Mellitus, Anxiety
- Trial name
- ERECT-PCI (NCT07444697)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Colorectal Cancer (CRC)
Normobaric Oxygen Therapy in Colorectal Cancer Patients
Colorectal cancer (CRC) patients undergoing chemotherapy often experience anemia, oxidative stress, and immune suppression, significantly impacting their quality of life and treatment outcomes.
- Trial name
- NBO-ONCO (NCT06946004)
- Testing
- Normobaric oxygen therapy
- Where
- Poland
- Volunteers
- 254 people
- Sponsor
- 4th Military Clinical Hospital with Polyclinic, Poland
Depression, Social Anxiety
Effectiveness and Cost Effectiveness of OkeyMind for Social Anxiety Among Youth
This randomized controlled trial aims to evaluate the effectiveness and cost-effectiveness of a mobile-based psychoeducation program (OkeyMind) in mitigating symptoms associated with social anxiety among youth.
- Trial name
- NCT06490315
- Testing
- OkeyMind intervention, Wait-list control
- Where
- Hong Kong
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Hong Kong Shue Yan University
Attention-Deficit and Hyperactivity Disorder, Anxiety
Correlating Real and Virtual World Behavioral Fluctuations in Adolescence
The present study will explore a new approach to ongoing evaluation and monitoring of fluctuations in personality traits via commercial video games.
- Conditions
- Attention-Deficit and Hyperactivity Disorder, Anxiety, Disruptive Mood Dysregulation Disorder, Depression
- Trial name
- NCT02281825
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Cancer, Sleep Disturbance
Wellness App for Sleep Disturbance in Hematological Cancer Patients
In a randomized controlled trial (RCT), the investigators will recruit participants to an 8-week "app-based wellness" intervention, followed by a 12-week follow-up period.
- Conditions
- Cancer, Sleep Disturbance, Anxiety, Depression
- Trial name
- Heme (NCT05294991)
- Testing
- Wellness app intervention #1, Wellness app intervention #2
- Where
- 3 sites in United States
- Volunteers
- 276 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Cancer
Remote Mindfulness Breathing Training for Patients Undergoing Chemotherapy
This randomized controlled trial will evaluate the effects of a mobile-delivered remote mindfulness breathing training program on symptom distress, fatigue, anxiety, and depression in adults with cancer who are receiving…
- Trial name
- NCT07806760
- Testing
- Mobile Remote Mindfulness Breathing Training, Brief Mindfulness Breathing Instruction
- Where
- 2 sites in Taiwan
- Volunteers
- 80 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Anxiety Disorders, Major Depressive Disorder
Acquisition and Analysis of Relationships Between Longitudinal Emotional Signals Produced by an Artificial Intelligence Algorithm and Self-questionnaires Used in the Psychiatric Follow-up of Patients With Mood and/or Anxiety Disorders: a Real-Environment Study.
The worldwide prevalence of anxiety and depression increased massively during the pandemic, with a 25% rise in the number of patients suffering from psychological distress.
- Trial name
- EMOACQ-1 (NCT05988840)
- Testing
- Acquisition and analysis of relationships between Longitudinal Emotional Signals produced by a software and Self-questionnaires.
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Emobot
Apical Periodontitis, Anxiety
Apical Periodontitis and Mental Health
This study is investigating the relationship between anxiety, depression and apical periodontitis (AP), a common oral inflammatory condition.
- Conditions
- Apical Periodontitis, Anxiety, Depression
- Trial name
- NCT06589076
- Testing
- Clinical and Radiographic assessment + Questionnaires
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Siena
Inflammation, Psychosocial Functioning
Mindfulness Meditation Neuroimaging Study for Undergraduates
This study is designed to test the effectiveness of mindfulness meditation intervention classes on psychosocial health outcomes.
- Conditions
- Inflammation, Psychosocial Functioning, Depression, Anxiety
- Trial name
- NCT05304052
- Testing
- Mindfulness Meditation classes
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Depression Anxiety Disorder, Geriatric Diseases
A Tripartite Biopsychosocial Intervention Program Enhances Mental Health and Quality of Life in Elderly Patients With Depression Secondary to Geriatric Diseases
The biopsychosocial integrated intervention program is an effective model for improving holistic health in elderly patients with geriatric disease-related secondary depression, significantly alleviating depressive symptoms…
- Conditions
- Depression Anxiety Disorder, Geriatric Diseases, Mental Health and Quality of Life in Elderly Patients
- Trial name
- NCT07002385
- Testing
- control group, Intervention group
- Where
- China
- Volunteers
- 166 people
- Sponsor
- Wenzhou Seventh People's Hospital
Post Traumatic Stress Disorder, Anxiety
PTSD Symptoms Among Health Workers and Public Service Providers After the COVID-19 Outbreak: A 3 Month Follow up
The aim of this study is to investigate the levels of trauma and mental symptoms (i.e., depression and anxiety) among health workers and public service providers 3 months after (T2) the strict social distancing government…
- Conditions
- Post Traumatic Stress Disorder, Anxiety, Depression
- Trial name
- NCT04442243
- Volunteers
- 889 people, healthy volunteers welcome
- Sponsor
- University of Oslo