Clinical trials: Depressive State
Depression
Computerized Cognitive Behavioral Therapy and Electroconvulsive Therapy
In an open-label feasibility study, fifteen will be recruited to participate in the study from among those who have already chosen of their own accord to undergo ECT (standard of care) at Yale Psychiatric Hospital for treatment…
- Trial name
- NCT02176473
- Testing
- Computerized Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University
Mental Health Disorder, Depression
Mobile Phone Based Intervention to Protect Mental Health in Healthcare Workers at Frontline Against COVID19
This study aims at evaluating the effectiveness of a mobile phone based intervention to prevent and manage mental health problems in healthcare workers at the frontline against COVID-19 in Spain.
- Conditions
- Mental Health Disorder, Depression, Posttraumatic Stress Disorder, Burnout
- Trial name
- PsyCovid_App (NCT04393818)
- Testing
- Intervention App
- Where
- Spain
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Depression
Unilateral Massage as a Potential Treatment for Depression
In depression, EEG studies have shown frontal asymmetry with relatively lower activity in the left hemisphere. In this study a moderate pressure massage will be conducted by a trained professional on one of the following…
- Trial name
- NCT01937897
- Testing
- Bi-lateral massage
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Older Adults, Depression
Educational and Cultural Engagement and Incidence of Health Adverse Events
This study evaluated if the social and cultural activities decrease the incidence of dementia and frailty conditions.
- Conditions
- Older Adults, Depression, Cognitive Decline
- Trial name
- NCT03987360
- Testing
- Observational
- Where
- Canada
- Volunteers
- 30,000 people
- Sponsor
- Jewish General Hospital
Depression, Generalized Anxiety
The Impact of Information Sources on Mental Health During the COVID-19 Pandemic
Study description: The present study seeks to investigate the impact of various sources of information on psychopathology, and specifically health anxiety, depression, and general anxiety, during the COVID-19 pandemic.
- Conditions
- Depression, Generalized Anxiety, Health Anxiety
- Trial name
- NCT04442360
- Testing
- Prospective study with two measurement points investigating the impact of viral mitigation protocols on mental health
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Depressive Disorder
Meditation Based Lifestyle Modification in Depression
To evaluate effectiveness of a 8-week behavioral Mind-Body-Intervention based on Yoga and Meditation in depressive outpatients.
- Trial name
- MBLM-D (NCT03652220)
- Testing
- Meditation Based Lifestyle Modification, Minimal treatment, Multimodal specific treatment:
- Where
- Germany
- Volunteers
- 81 people
- Sponsor
- Diakonie Kliniken Zschadraß
Dysthymic Disorder, Depressive Disorder NOS
Duloxetine for Chronic Depression: a Double-blind Study
The investigators are studying a new antidepressant medicine, duloxetine, for the treatment of people with chronic depression. Duloxetine (trade name Cymbalta) was recently approved by the FDA for the treatment of major…
- Trial name
- NCT00360724
- Testing
- Duloxetine (Cymbalta)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- New York State Psychiatric Institute
Anxiety, Depression
Evaluating Knowledge Insight Tools (KIT) for Reducing Anxiety and Low Mood in UK Secondary School Students
Background and Study Aims: Secondary school students are reporting unprecedented levels of anxiety and mood difficulties. To ensure that the needs of all young people are met, there is a need to evaluate more accessible forms of…
- Conditions
- Anxiety, Depression, Internalizing Problems, Low Mood
- Trial name
- NCT06188962
- Testing
- CBT-informed school-based counselling
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University College, London
Major Depressive Disorder
Accelerated Treatment of Depressive Patients With tDCS
A randomized, controlled three-arm study is planned to investigate the effectiveness and feasibility of an accelerated home-based tDCS application (3 weeks of transcranial direct current stimulation at home, twice daily).
- Trial name
- AcctDCS (NCT07444242)
- Testing
- Transcranial direct current stimulation
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University of Regensburg
Idiopathic Normal Pressure Hydrocephalus
Gait Pattern and Experienced Global Change After Shunt Surgery in Idiopathic Normal Pressure Hydrocephalus
Part 1 Patients with idiopathic Normal Pressure Hydrocephalus (iNPH) have variable disabilities regarding gait, balance, cognition and continence.
- Trial name
- NCT04795089
- Testing
- Shunt surgery
- Where
- Sweden
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Post-stroke Depression
Transcranial Alternating Current Stimulation Treating Post-stroke Depression
Post-stroke depression (PSD) is one of the most common complications after stroke, with a high prevalence. PSD can affect prognosis and rehabilitation of stroke, increase risks of mortality and suicide, and escalate the economic…
- Trial name
- NCT03903068
- Testing
- NEXALIN ADI AC stimulator, Pseudo-stimulator
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Xuanwu Hospital, Beijing
Laryngeal Carcinoma, Quality of Life (QOL)
Quality of Life and Functional Outcomes in Laryngeal Cancer Patients
Laryngeal squamous cell carcinomas are head and neck malignancies that directly affect both swallowing and voice functions and are associated with a significant deterioration in patients' quality of life throughout the treatment…
- Conditions
- Laryngeal Carcinoma, Quality of Life (QOL), Patient Satisfaction, Voice Quality
- Trial name
- QoL in LSSC (NCT07320820)
- Testing
- Quality of Life Assessment, Patient Satisfaction Assessment, Swallowing Function Assessment
- Volunteers
- 120 people
- Sponsor
- Saglik Bilimleri Universitesi
Depression
Effectiveness and Dissemination of Computer-based Cognitive Behavioral Therapy and Online Stress Management Program for Adolescents
The aim of this study is to investigate the effectiveness of a computer-based Cognitive Behavioral Therapy (CCBT) and online stress management program for adolescents, and identify the characteristics of depressed adolescents…
- Trial name
- NCT04957680
- Testing
- CCBT
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Seoul National University Hospital
Addiction, Depression/Anxiety
Healing Lodge First Face Training Evaluation Study
The purpose of this study is to evaluate a culturally grounded training program, xaʔtus (meaning First Face) for Mental Health. This program will train community members in how to recognize and respond to youth and adults…
- Conditions
- Addiction, Depression/Anxiety, Trauma, Psychological, Self-harm
- Trial name
- NCT06290180
- Testing
- First Face for Mental Heatlh
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Major Depression, Schizophrenia
Proactive Psychiatry Consultation for Patients With Cancer and Severe Mental Illness
Individuals with severe mental illness (SMI) including schizophrenia and bipolar disorder are dying younger than the general population; cancer is a leading cause of death in this population.
- Conditions
- Major Depression, Schizophrenia, Bipolar Disorder, Lung Cancer
- Trial name
- NCT02594696
- Testing
- Proactive Psychiatry Consultation (PPC)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Sensory Processing Sensitivity
Mindfulness-Based Stress Reduction (MBSR) for People High on the Personality Trait Sensory Processing Sensitivity: A Mixed Methods Study
This study investigates the efficacy of MBSR training in alleviating stress-related symptoms among individuals with high sensory processing sensitivity.
- Trial name
- MindSens (NCT06390020)
- Testing
- MBSR
- Where
- Netherlands
- Volunteers
- 52 people
- Sponsor
- Radboud University Medical Center
Anxiety, Depression
A Prospective and Experimental Study on the Effect of One-Day of Acceptance and Commitment Therapy (ACT) on Psychological Flexibility, Psychological Capital, Anxiety and Depression Among Undergraduate Students.
The goal of this study is to examine the effect of a one-day ACT intervention on psychological flexibility and psychological capital among undergraduate students at UTM who have anxiety and depression.
- Trial name
- ACT (NCT06832462)
- Testing
- Acceptance and Commitment Therapy
- Where
- Malaysia
- Volunteers
- 61 people
- Sponsor
- Universiti Teknologi Malaysia
Stroke, Depressive Symptoms
The Effect of Instant Message Intervention for Psychological Well-being Among Stroke Survivors
The proposed pilot trial aims to evaluate the feasibility of iCBT based EMI, which is a real-time, real-world, personalised and cost-effective approach, for stroke survivors' psychological well-being.
- Conditions
- Stroke, Depressive Symptoms, Mobile Phone Use
- Trial name
- NCT05490069
- Testing
- iCBT-based EMI
- Where
- 7 sites in Hong Kong
- Volunteers
- 40 people
- Sponsor
- The University of Hong Kong
Type 2 Diabetes
Effects of Peer Support and Yoga Music on T2DM With Depression and Sleep Disorders
40 patients with Type 2 Diabetes Mellitus who also have sleep disorders and mild depression in the community will be recruited and stochastically divided into the intervention group and the control group.
- Trial name
- NCT02198989
- Testing
- peer support and yoga music therapy
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Guang Ning
Postoperative Pain, Acute, Postoperative Depression
REmotely-delivered Supportive Programs for Improving Surgical Pain and disTrEss
The purpose of this research study is to learn how two different supportive programs may help women feel better after surgery. This study will measure if one type of supportive program is more useful than the other for improving…
- Conditions
- Postoperative Pain, Acute, Postoperative Depression, Anxiety, Sleep Disturbance
- Trial name
- NCT05625360
- Testing
- eHealth Mindful Movement and Breathing, Life Impacts Reflection, PROMIS Questionnaires
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.