Clinical trials: Depressive State
Burnout, Professional, Mental Health Issue
Ambulatory Electrodermal Activity Measurements as Part of Identification and Prevention of Job Burnout
The study investigates the associations of ambulatory electrodermal activity (EDA) measurements with mental well-being at work, especially job burnout.
- Conditions
- Burnout, Professional, Mental Health Issue, Anxiety, Depression
- Trial name
- NCT05317793
- Where
- 3 sites in Finland
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Overweight and Obesity, Eating Disorders
Wellness Education Intervention
Individuals suffering from depression and anxiety have an increased risk of obesity due to multiple factors such as side effects to psychotropic medications, associated appetite dysregulation, disruption of sleep, anergia leading…
- Conditions
- Overweight and Obesity, Eating Disorders, Depression, Anxiety
- Trial name
- NCT04962321
- Testing
- Wellness Education
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Texas Southwestern Medical Center
Depression, Depressive Disorder
Acute Aerobic Exercise and Neuroplasticity in Depression
Depression is associated with a disruption in the mechanisms that regulate neuroplasticity. Effective treatment and rehabilitation of depression, and other neurological and neuropsychiatric disorders, relies on neuroplasticity.
- Trial name
- NCT02839837
- Testing
- Aerobic Exercise, Paired Associative Stimulation
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Multiple Sclerosis
Factors That Influence Compliance With Disease-Modifying Therapy in Multiple Sclerosis
The purpose of this study is to evaluate the coorelation between patient factors, health care provider factors, drug factors and compliance in patients with relapsing forms of multiple sclerosis (RMS) treated with Disease…
- Trial name
- NCT00223457
- Testing
- Factors that influence compliance
- Where
- United States
- Volunteers
- 1,040 people
- Sponsor
- University of Texas Southwestern Medical Center
Depression, Postpartum
Estimating the Prevalence of Postpartum Anxiety and Depression in the Context of the Coronavirus Disease (COVID-19) Pandemic
In December 2019, infection with a new coronavirus Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) emerged in China and has since spread throughout the world.
- Trial name
- PsyCOVIDUM (NCT04852757)
- Where
- France
- Volunteers
- 2,580 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Depression
Transcranial Magnetic Stimulation: Treatment Trial for Depressed Adolescents
This is a study to assess the effectiveness and safety of repetitive transcranial magnetic stimulation (rTMS) as a treatment for depressed 13-18 year olds.
- Trial name
- NCT00470028
- Testing
- Transcranial Magnetic Stimulation
- Where
- 3 sites in Australia
- Volunteers
- 30 people
- Sponsor
- The University of New South Wales
Postpartum Depression (PPD)
Intranasal Dexmedetomidine for Postpartum Depression Prevention
Brief Title: Intranasal Dexmedetomidine for Postpartum Depression Prevention: A Randomized Trial This study aims to evaluate the effect of intranasal dexmedetomidine (Dex) administered before combined spinal-epidural labor…
- Trial name
- NCT07501728
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Chengdu Jinjiang Maternity and Child Health Hospital
Questionnaire Designs, COVID-19 Pandemic
Psychological Effects of the COVID-19 Pandemic on the Hungarian Adult Population
The aim of the study is to explore the psychological effects of the COVID-19 pandemic among Hungarian adults with the use of an anonymous online questionnaire that consists of 65 items.
- Conditions
- Questionnaire Designs, COVID-19 Pandemic, Psychological Stress, Coping Skills
- Trial name
- NCT04426266
- Where
- Hungary
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- Szeged University
Depression, Postpartum
Prevention of Postpartum Depression in Low-Income Women
This study will determine whether a prevention program reduces the incidence of postpartum depression in pregnant women who receive public assistance and are at risk for postpartum depression.
- Trial name
- NCT00053651
- Testing
- Survival Skills for Moms with New Babies
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Depression
Tai Chi Intervention for Chinese Americans With Depression
The purpose of this study is to conduct a pilot randomized controlled trial (RCT) that provides the feasibility, safety, and preliminary efficacy data required to design a large scale trial evaluating Tai Chi for Chinese…
- Trial name
- NCT01619631
- Testing
- 12-week Tai Chi intervention, Education control group
- Where
- 2 sites in United States
- Volunteers
- 94 people
- Sponsor
- Massachusetts General Hospital
Bipolar Disorder
Cytidine and Omega-3 Fatty Acids in Bipolar Disorder
The goal of the proposed clinical trial is to assess the effect of oral cytidine and omega-3 fatty acids (O3FA) on bipolar disorder symptoms.
- Trial name
- NCT00854737
- Testing
- cytidine, omega-3 fatty acids
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Mclean Hospital
Depressive Symptoms, Anxiety
Psychopharmacology of Psilocybin in Cancer Patients
This research is being done to study the psychological effects of psilocybin in cancer patients. Psilocybin is a naturally occurring substance found in some mushrooms that some cultures have used for centuries in religious…
- Conditions
- Depressive Symptoms, Anxiety, Cancer
- Trial name
- NCT00465595
- Testing
- psilocybin
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Johns Hopkins University
Depressive Disorder
Paxil Japanese Post Marketing Paediatric Study in Depression (Double-blind, Placebo Controlled Study)
This study is designed to compare the efficacy of oral paroxetine 10 to 40 mg/day (initial dose:10 mg/day) versus placebo administered once daily (after evening meal) for 8 weeks in children and adolescents with major depressive…
- Trial name
- NCT00812812
- Testing
- paroxetine 10mg tablet, paroxetine 20mg tablet
- Where
- 33 sites in Japan
- Volunteers
- 56 people
- Sponsor
- GlaxoSmithKline
Major Depressive Disorder
Biomarkers in Repetitive Transcranial Magnetic Stimulation (rTMS) for Adolescent Depression
The Researchers are going to gather information regarding the use of rTMS as a treatment for depression in adolescents with Major Depressive Disorder.
- Trial name
- NCT03363919
- Testing
- NeuroStar TMS Therapy® System, NeuroStar XPLOR®
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Mayo Clinic
Depression
Study Where Pharmaco Magnetic Resonance Imaging (MRI) Effects of AZD6765 Will be Compared to Placebo in Depressive Male and Female Subjects
The purpose of this study is to determine the effect of a single dose infusion of AZD 6765 compared with placebo and ketamine on the blood oxygen level dependent signal using fMRI (functional Magnetic Resonance Imaging) in…
- Trial name
- NCT01046630
- Testing
- AZD6765, Ketamine
- Where
- 2 sites in United Kingdom
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Fibromyalgia, Depression
Testing Interventions for Patients With Fibromyalgia and Depression
Chronic pain is a major health problem. It causes high economic and social costs around the world and severely impairs the quality of life of those who suffer from it. Chronic pain and major depression frequently co-occur.
- Trial name
- NCT03207828
- Testing
- Behavioral activation, Usual care
- Where
- Chile
- Volunteers
- 90 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Depressive Disorder, Treatment-Resistant
rTMS With and Without Text4Support for the Treatment of Resistant Depression.
This study is a multicenter prospective, parallel design, two-arm, rater-blinded randomized controlled pilot trial. Participants will be randomly assigned to one of two treatment conditions.
- Trial name
- NCT05570344
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Repetitive Transcranial Magnetic Stimulation (rTMS) Plus Text4Support
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- University of Alberta
Dementia, Depression
Testing the Feasibility of the Individualized Positive Psychosocial Intervention (IPPI)
The goal of this clinical trial is to test the feasibility of the Individualized Positive Psychosocial Interaction (IPPI) with 108 nursing home residents living with dementia and distress or depressive symptoms.
- Conditions
- Dementia, Depression, Behavior
- Trial name
- IPPI (NCT05980299)
- Testing
- Individualized Positive Psychosocial Interaction
- Where
- 7 sites in United States
- Volunteers
- 200 people
- Sponsor
- Miami University
Bipolar Depression
Aripiprazole Treatment of Bipolar Depression
This is a study of addition of aripirazole to the treatment of bipolar depressed patients who are not better on the medications that they are currently receiving.
- Trial name
- NCT00198198
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Indiana University
Chronic Pain Due to Injury, Acute Pain
Evaluating the Impact of Focused Muscle Contraction Therapy in Retire APF Players
This study will investigate the effects of an exercise intervention on retired American professional football (APF) players. A total of 20 retired APF players (≥ 18 years of age), who suffer from chronic pain, will be enrolled.
- Conditions
- Chronic Pain Due to Injury, Acute Pain, Depression, Brain Injuries
- Trial name
- GH-APF (NCT04822311)
- Testing
- Experimental: Investigate the effects of an exercise intervention on retired APF players
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Illinois Chicago
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