Clinical trials: Depressive State
Eating Disorders in Adolescence, Eating Disorders
Animal-Assisted Therapy in Adolescents With Eating Disorders
This study aims to improve eating disorders symptomatology, mental, psychosocial and physical health, quality of life, strength and body composition of adolescents with eating disorders by the development of a dog-assisted…
- Conditions
- Eating Disorders in Adolescence, Eating Disorders, Anorexia Nervosa/Bulimia
- Trial name
- NCT04869423
- Testing
- Dog-Assisted Therapy
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Daniel Collado-Mateo
Depressed Insomniac Co-morbid Patients
Trazodone on NREM Sleep Stage Ⅲ in Depressed Insomniac Co-morbid Patients
This study used polysomnographic technology and randomly selected 60 patients who met the diagnostic criteria for depression and non-organic insomnia as stipulated in DSM-5 into an intervention group (n=30) and a control group…
- Trial name
- n-REMSS (NCT06740188)
- Testing
- 5-hydroxytryptamine balanced antidepressants trazodone, Citalopram hydrobromide combined with zolpidem
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Tongji University
Bipolar Disorder Depression
Scopolamine in Bipolar Depression
This is a single-site, randomised, double-blind, placebo-controlled, parallel, phase IIb clinical trial. The primary objective of the SCOPE-BD study is to investigate the efficacy and safety of IV Scopolamine, compared to…
- Trial name
- SCOPE-BD (NCT04211961)
- Testing
- Scopolamine
- Where
- Ireland
- Volunteers
- 55 people
- Sponsor
- Dr. Brian Hallahan
Stroke, Depression
Task-Oriented Rehab With SaeboFlex: Impact on Independence, Visual Motor Skills, and Depression in Stroke Patients
Objective: The SaeboFlex orthosis is designed to assist individuals with upper extremity weakness in performing repetitive tasks.
- Conditions
- Stroke, Depression, Splints
- Trial name
- Randomized (NCT06569654)
- Testing
- Saebo splint
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Fenerbahce University
Generalized Anxiety, Social Phobia
Integrated Mental Health Care and Vocational Rehabilitation to Individuals on Sick Leave Due to Anxiety and Depression
The purpose of this study is to investigate the efficacy of 1) a stepped mental health care intervention and 2) an integrated mental health care and vocational rehabilitation intervention for people on sick leave because of…
- Conditions
- Generalized Anxiety, Social Phobia, Panic Disorder, Depression
- Trial name
- IBBIS (NCT02872051)
- Testing
- IBBIS mental health care and standard vocational rehabilitation, Integrated mental health care and vocational rehabilitation
- Where
- Denmark
- Volunteers
- 631 people
- Sponsor
- Amager Hospital
Diabetes Mellitus, Type 2, Depression
Program ACTIVE: Phase 2
The present study seeks to tailor the original Program ACTIVE (Adults Coming Together to Increase Vital Exercise) to meet the cultural norms and needs of adult Black men with comorbid Type 2 diabetes and depression by using focus…
- Trial name
- NCT04369001
- Testing
- Community-Based Exercise, Cognitive Behavioral Therapy
- Sponsor
- University of Michigan
Postpartum Depression
Behavioral Change in the Mother-Infant Dyad: Preventing Postpartum Depression
Postpartum depression (PPD) is undertreated and the consequences of this are substantial for women and children. Studies show that infant cry/fuss and sleep behavior are associated with PPD, and that parenting interventions can…
- Trial name
- NCT01379781
- Testing
- Behavioral Intervention for PPD
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Depression
Ketamine Interleaved With Electroconvulsive Therapy for Depression
Pragmatic, randomised, controlled, parallel group, pilot clinical trial of ketamine vs. midazolam interleaved with electroconvulsive therapy (ECT) as an adjunctive treatment for a major depressive episode.
- Trial name
- NCT04082858
- Testing
- Ketamine, Midazolam
- Where
- Ireland
- Volunteers
- 3 people
- Sponsor
- St Patrick's Hospital, Ireland
Major Depressive Disorder, Major Depression
Antidepressant Treatment of Mexican-Americans: UCLA Pharmacogenetics and Pharmacogenomics Research Group
Our goal is to study pharmacogenetics in Mexican-Americans, using depression treatments as a proof of the concept that pharmacogenetic approaches can be used to optimize treatment strategies for common and complex disorders in…
- Conditions
- Major Depressive Disorder, Major Depression, Unipolar Depression
- Trial name
- NCT00265291
- Testing
- fluoxetine or desipramine
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- National Institute of General Medical Sciences (NIGMS)
Interstitial Lung Disease
Clinical Impact of HOME Oxygen SATURation Measurement (SATURHOME)
The use of saturometry at home is more and more widespread in patients suffering from interstitial pulmonary diseases (IPD), the patients seeing it as reassurance and a concrete way to follow the evolution of their disease.
- Trial name
- SATURHOME (NCT04624191)
- Testing
- Saturation at home
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Laval University
Depression, Bipolar, Depression, Unipolar
Pramipexole to Target "Anhedonic Depression"
The heterogeneity of depression suggests that different neurocircuits and pathophysiological mechanisms are involved. Anhedonia - the inability to experience pleasure from, or the lack of motivation to carry out, usually…
- Conditions
- Depression, Bipolar, Depression, Unipolar, Dysthymia, Anhedonia
- Trial name
- PILOT-PRAXOL (NCT04121091)
- Testing
- Pramipexole Pill
- Where
- Sweden
- Volunteers
- 13 people
- Sponsor
- Region Skane
Prenatal Anxiety, Prenatal Depression
Effectiveness of an Online Biopsychosocial Intervention to Improve Well-being and Mental Health During Pregnancy
This study aims to develop and implement a preventive intervention through a mobile application to help pregnant women feel better emotionally and cope with the changes of pregnancy in a more positive way.
- Conditions
- Prenatal Anxiety, Prenatal Depression, Wellbeing, Obstetrical Complications
- Trial name
- BienGestar (NCT06871397)
- Testing
- Biopsychosocial Cognitive Behavioral Intervention
- Where
- Spain
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Bariatric Surgery, Depression
Laughter Yoga Effect Depression, Serotonin Levels With Bariatric Surgery Patient
The goal of this a quasi-trial model with pre and post-test control group is to determine the effect of laughter yoga on depression and serotonin levels in patients undergoing bariatric surgery.
- Trial name
- NCT06020079
- Testing
- laughter yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Sleep Initiation and Maintenance Disorders, Depression
Self-help Smartphone-delivered Cognitive Behavioral Therapy for Insomnia in People With Depression and Insomnia
This randomized controlled trial aims to examine the effectiveness of a self-help smartphone-delivered cognitive behavioral therapy for insomnia, compared to a waitlist control, in treating people with major depression and…
- Trial name
- NCT04228146
- Testing
- Cognitive Behavioral Therapy for Insomnia, Waitlist Control
- Where
- China
- Volunteers
- 285 people
- Sponsor
- The University of Hong Kong
Health Behaviors, Obesity
Goal Setting for Health Behavior and Psychosocial Issues in Primary Care
The purpose of this delayed cluster randomized intervention trial is to evaluate primary care strategies to increase goal setting, shared decision-making and evidence-based support and counseling for health behaviors and…
- Conditions
- Health Behaviors, Obesity, Substance Abuse, Anxiety
- Trial name
- MOHR (NCT01825746)
- Testing
- Implementation of the MOHR assessment in primary care workflow
- Where
- 8 sites in United States
- Volunteers
- 3,591 people
- Sponsor
- Virginia Commonwealth University
HEART DISEASE, Liver Failure
Somatic Disease Among Alcohol Abusers in an Out-day Patients' Clinic
Alcohol abuse is associated with a variety of clinical diseases, but studies on prevalence of different somatic diseases among alcohol abusers are lacking. Studies on populations in an out-day patients' clinic are also lacking.
- Conditions
- HEART DISEASE, Liver Failure, DEPRESSIVE DISORDER, Alcoholic Neuropathy
- Trial name
- NCT01081197
- Testing
- Psychiatric and somatic examinations and ,if clinical indicated, treatment
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Helse Nord-Trøndelag HF
Postnatal Depression, Quality of Life
mHealth Intervention to Reduce Maternal Postnatal Depression and Promote Family Health
The proposed study is to test the effectiveness of a culturally-attuned, family-based mobile health (mHealth) intervention in reducing symptoms of postnatal depression and promoting health among expectant mothers in Hong Kong.
- Conditions
- Postnatal Depression, Quality of Life, Family Relations
- Trial name
- NCT05275413
- Testing
- family-based mHealth Intervention, mother-only mHealth Intervention, Health education
- Where
- 2 sites in Hong Kong
- Volunteers
- 1,578 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Treatment Resistant Depression
Intensive Accelerated iTBS for the Treatment-Resistant Depression
This study is a multicenter, randomized, double-blind, and sham-controlled trial using most intensive aiTBS protocol (10 sessions daily over 5 consecutive days at triple the standard per-session dose) to investigate the…
- Trial name
- NCT06166082
- Testing
- Active iTBS-DLPFC
- Where
- 5 sites in China
- Volunteers
- 130 people
- Sponsor
- Changping Laboratory
Major Depression, Minor Depression
Neuropattern - Assessment of a Translational Diagnostic Tool for Depression, Adjustment- and Somatoform-disorders
Neuropattern is a first translational tool in stress medicine. Neuropattern is a diagnostic tool, which can be applied by in- and outpatients and physicians to detect dysregulation in the stress response network.
- Conditions
- Major Depression, Minor Depression, Somatoform Disorders, Adjustment Disorders
- Trial name
- Neuropattern (NCT01062880)
- Testing
- self-guided internet modules
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- University of Trier
Depression, Bipolar
Olanzapine Treatment of Patients With Bipolar I Disorder
The purpose of this study is to assess whether olanzapine is superior to placebo in patients with bipolar depression.
- Trial name
- NCT00510146
- Testing
- Olanzapine
- Where
- 16 sites in China, Japan and 1 more
- Volunteers
- 514 people
- Sponsor
- Eli Lilly and Company
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