Clinical trials: Depressive State
Parkinson Disease, Depression
Pramipexole Versus Placebo in Parkinson's Disease (PD) Patients With Depressive Symptoms
Parkinsons Disease (PD) is caused by a decrease of dopamine in a particular part of the brain. Dopamine is a messenger substance (neurotransmitter) that is used by the cells of the brain (nerve cells) to control and harmonize…
- Trial name
- NCT00297778
- Testing
- Pramipexole
- Where
- 77 sites in Austria, Finland and 11 more
- Volunteers
- 296 people
- Sponsor
- Boehringer Ingelheim
Psychological Distress
Existential Group Treatment for Older Adults (75+) With Psychological Distress in Primary Care
Symptoms of depression and anxiety are common in older adults, and high suicide rates are observed in this age group in Sweden, as in many countries around the globe.
- Trial name
- NCT05503485
- Testing
- Existential group treatment, Supportive telephone calls
- Where
- 7 sites in Sweden
- Volunteers
- 140 people
- Sponsor
- Göteborg University
Infertility, Female, Depression
Educational and Supportive Care to Depressed Infertile Females
Infertility affects married adults, and In Vitro Fertilization (IVF) is an Assisted Reproductive Technology (ART) that can be treated. Women undergoing IVF are more likely to experience depression.
- Conditions
- Infertility, Female, Depression, IVF
- Trial name
- NCT06022640
- Testing
- Educational and supportive care
- Where
- Iraq
- Volunteers
- 150 people
- Sponsor
- Al-Rasheed University College
Alzheimer's Disease, Dementia
Safety and Efficacy Study of Ladostigil in Mild to Moderate Probable Alzheimer's Disease
For many, Alzheimer's disease is the number one medical issue facing our aging society. It is a late onset neurodegenerative disease, frequently under diagnosed, that impairs memory and cognitive performance.
- Conditions
- Alzheimer's Disease, Dementia, Memory Loss, Cognitive Impairment
- Trial name
- NCT01354691
- Testing
- ladostigil hemitartrate
- Where
- 19 sites in Austria, Croatia and 3 more
- Volunteers
- 200 people
- Sponsor
- Avraham Pharmaceuticals Ltd
Alzheimers' Disease
Cognitive Behavioural Therapy for Persons With MCI or Mild Dementia
A total of 200 home dwelling participants, who fulfil the inclusion criteria, Alzheimer's disease, will be recruited from three hospitals in Norway.
- Trial name
- NCT02013518
- Testing
- Cognitive Behavioural Therapy
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Major Depressive Disorder (MDD)
Implementation of a Multiple Intervention to Promote Healthy Lifestyles in Patients With Depression
This clinical trial aims to investigate whether an integrative approach combining education on the Mediterranean diet and physical activity (PA) can significantly reduce depressive symptomatology in individuals with major…
- Trial name
- NCT06990035
- Testing
- Mediterranean diet lessons program, Physical activity
- Where
- 2 sites in Italy
- Volunteers
- 120 people
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Help-Seeking Behavior, Depression
Improving Help-seeking for Depression Care in Nepal
Depression is a serious public health concern worldwide due to its high prevalence rate and significant emotional and financial burden on individuals, their families, and society.
- Trial name
- NCT06574074
- Testing
- Gain-Life (Give informAtIoN to transform Life)
- Where
- Nepal
- Volunteers
- 286 people
- Sponsor
- Transcultural Psychosocial Organization Nepal
Insomnia Chronic, Insomnia
Effects of Insomnia Treatment on Metabolism in Patients With Depression
This project will examine changes in metabolism and depressive symptoms after receiving CBT-I in 30 subjects with insomnia disorder and MDD.
- Conditions
- Insomnia Chronic, Insomnia, Insomnia, Primary, Depression
- Trial name
- NCT04719143
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Pennsylvania
Insomnia
Eszopiclone Co-Administered With Escitalopram for Insomnia in Elderly Adults With Major Depressive Disorder
Research has established the incidence of insomnia increases with age and the possible causes contributing to sleep problems in the elderly are still being explored and debated.
- Trial name
- NCT00813735
- Testing
- Eszopiclone, Escitalopram
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lehigh Center for Clinical Research
Depression, Anxiety
More Individualized Care: Assessment and Recovery Through Engagement
The MI-CARE trial tests 12 months of telephone-based nurse care management for patients with depressive symptoms who take or have taken opioids at some time.
- Conditions
- Depression, Anxiety, Opioid-Related Disorders, Pain, Chronic
- Trial name
- MI-CARE (NCT05122676)
- Testing
- More Individualized Care: Assessment and Recovery through Engagement (MI-CARE)
- Where
- 2 sites in United States
- Volunteers
- 805 people
- Sponsor
- Kaiser Permanente
Unipolar Depression
RCT of Psychoeducational Program of Depression
The purpose of the study is to test the efficacy of a psychoeducational group program on unipolar depression
- Trial name
- NCT00319540
- Testing
- Control with depression course (CWD)
- Where
- Norway
- Volunteers
- 155 people
- Sponsor
- Norwegian Institute of Public Health
Acute Coronary Syndrome
Direct Angioplasty for Non ST Elevation Acute Coronary Events: DANCE Pilot Study
This is a pilot feasibility study to evaluate if patients with ST depression Acute Coronary Syndrome who are taken directly to the catheter laboratory for angiogram and angioplasty +/- stents will fare better that patients who…
- Trial name
- DANCE (NCT01172990)
- Testing
- Immediate Invasive Management, Conventional Management
- Where
- United Kingdom
- Volunteers
- 108 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Depressive Symptoms
A Pilot Investigation of Clinician-guided Internet-Delivered Cognitive Behavioural Therapy for Depressed Patients
This study aims to explore the efficacy and acceptability of a clinician-guided internet-based Cognitive Behavioural Therapy (iCBT) programme for patients with depression, in Singapore.
- Trial name
- iCBT (NCT04100785)
- Testing
- Internet-delivered Cognitive Behavioural Therapy
- Volunteers
- 55 people
- Sponsor
- Institute of Mental Health, Singapore
Major Depressive Disorder, Recurrent, Depressive Episode
Confirmation Bias Towards Treatments of Depressive Disorders in Social Tagging
The study examines whether people primarily want to confirm their prior attitudes in health-related information search, in an online environment using social tags for navigation.
- Conditions
- Major Depressive Disorder, Recurrent, Depressive Episode, Depressive Disorder, Major, Depression
- Trial name
- NCT03899168
- Testing
- Social Tag Popularity, Confidence in Prior Attitudes, Source Credibility
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Leibniz-Institut für Wissensmedien
Postpartum Recovery, Mother-infant Bonding
Labor Epidural Analgesia and Mother-Infant Bonding After Vaginal Delivery
This prospective observational cohort study aims to evaluate the association between postpartum recovery quality and mother-infant bonding in women undergoing vaginal delivery.
- Conditions
- Postpartum Recovery, Mother-infant Bonding, Labor Pain
- Trial name
- NCT07582289
- Testing
- Labor Epidural Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Ataturk University
Depressive Symptoms, Metabolic Syndrome X
Reducing Disparities in Late Life Depression and Metabolic Syndrome
Linkages between depression and cardiovascular disease have been well documented. These appear to be more than associations, and may reflect causal relationships through a number of proposed pathways, including decreased physical…
- Conditions
- Depressive Symptoms, Metabolic Syndrome X, Overweight, Obesity
- Trial name
- BRIGHTEN-Heart (NCT01428791)
- Testing
- Generations older adult membership program, BRIGHTEN Heart Virtual Team intervention
- Where
- 2 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Anxiety Disorders
"Machine Learning Analysis of Lingual Colorimetry and MADRS Anxiety-Depression Score in Acupuncture Patients"
This observational study aims to assess the potential relationship between tongue colorimetry (using standardized photographic techniques) and anxiety-depression scores measured by the Montgomery-Åsberg Depression Rating Scale…
- Trial name
- ML_AcuTongue (NCT06899490)
- Where
- France
- Volunteers
- 466 people, healthy volunteers welcome
- Sponsor
- Dr Benoit Bataille
Substance Use Disorder (SUD), Anxiety
Effects of Qigong Exercise on Anxiety and Depression in Patients Receiving Inpatient Treatment for Substance Use Disorder
Patients receiving inpatient treatment for substance use disorder may experience anxiety and depressive symptoms. Qigong is a mind-body exercise that combines gentle movements, breathing techniques, and relaxation.
- Conditions
- Substance Use Disorder (SUD), Anxiety, Depression
- Trial name
- NCT07909447
- Testing
- Qigong Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Uskudar University
Stress, Psychological, Depression
The Efficacy of a Mobile Application for Treating Depression and Anxiety Symptoms
This was a 12-week, parallel randomised controlled trial, including a 6-week follow-up. The trial compared a group of university students (N = 84) receiving a mobile CBT application intervention ("Feel Stress Free") to a…
- Conditions
- Stress, Psychological, Depression, Anxiety
- Trial name
- NCT03032952
- Testing
- "Feel Stress Free" mobile application
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University College, London
Treatment Resistant Depression
Belief Updating in Treatment Resistant Depression
Major depressive disorder (MDD) is characterized by a cognitive triad of negative beliefs about oneself, the future and the world.
- Trial name
- KETABELIEF (NCT05577247)
- Testing
- functional magnetic resonance imaging
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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