Clinical trials: Depressive State
Fibromyalgia Syndrome
Efficacy of Different Types of Exercises in Women With Fibromyalgia Syndrome.
Objective: To demonstrate the most effective exercise intervention for women with fibromyalgia syndrome on the pain, quality of life, depression, and body composition through a comparative study of three types of exercise…
- Trial name
- NCT04426864
- Testing
- Supervised Aerobic Plus Stretching Exercises, Supervised Resistance Plus Stretching Exercises Group, Home-based Stretching Exercises Group
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Pamukkale University
Depression
PEER Interactive to Inform the Prescription of Medications
Improving the prescription accuracy of psychotropic medications for military personnel diagnosed with neuropsychiatric disorders is imperative to promote accelerated treatment response and recovery.
- Trial name
- NCT04620499
- Testing
- EEG
- Where
- 2 sites in Canada
- Volunteers
- 150 people
- Sponsor
- University of Ottawa
Depression
Italian Network for the Improvement of Compliance in Depression
The RIMAT-De study (Rete Italiana per il Miglioramento dell'Adesione al Trattamento nella Depressione) is a multicentric Randomized Controlled Clinical Trial aiming at identifying the best strategies available to reduce the poor…
- Trial name
- NCT01292499
- Testing
- Psychotherapy, Psychoeducation, Psychoeducation and psychotherapy
- Where
- Italy
- Volunteers
- 1,264 people
- Sponsor
- Ospedale Amedeo di Savoia
Post Partum Depression, Bipolar Disorder
Neuroimaging Epigenetics of Prospective Postpartum Depression Biomarkers
Through a recent cross species translational experiment, researchers have identified a set of epigenetic marks capable of predicting postpartum depression with greater than 85% accuracy.
- Trial name
- NCT03638687
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Weaning Failure, Central Respiratory Depression
Exploration of Mechanisms for Weaning Failure
This study is a prospective physiologic study. The primary study population will be adult invasive tracheal intubated patients with COPD, and investigators will collect relevant demographic data, vital signs, and baseline…
- Conditions
- Weaning Failure, Central Respiratory Depression, Diaphragm Injury, Phrenic Nerve Disorder
- Trial name
- NCT06424314
- Testing
- Monitoring of respiratory mechanics parameters
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Major Depressive Disorder
A Phase I/II Study of PDC-1421 for Treating Depression in Cancer Patients
The purpose of this study is to evaluate the safety and the effective doses of PDC-1421 in cancer patients with depression.
- Trial name
- NCT03833206
- Testing
- PDC-1421 Capsule
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- BioLite, Inc.
Mental Health Issue, Hiv
Healthy Mothers: an Intervention to Support Perinatal Women Living With HIV in Kenya
The investigators will recruit 40 pregnant women living with HIV divided into 2 groups (n=20 intervention group, n=20 control group).
- Conditions
- Mental Health Issue, Hiv, Breastfeeding, Exclusive
- Trial name
- NCT05219552
- Testing
- personalized lactation support
- Where
- 2 sites in Kenya
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Depression
Riluzole to Treat Major Depression
This study will examine the safety and effectiveness of the drug riluzole (Rilutek® (Registered Trademark)) for short-term treatment of depression symptoms, such as depressed mood, psychomotor retardation, and excessive sleeping.
- Trial name
- NCT00026052
- Testing
- riluzole
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- National Institute of Mental Health (NIMH)
Rare Diseases, Fatigue
Fatigue, Depressive Disorders and Insomnia in Adult Patients with Marfan Syndrome and Ehlers-Danlos Syndrome: Survey
The goal of this observational study is to describe and assess the presence of perceived fatigue in subjects with MFS and EDS. the main question it aims to answer through the FSS instrument is: The relationship of fatigue with…
- Conditions
- Rare Diseases, Fatigue, Insomnia, Depression
- Trial name
- FAMED (NCT05712564)
- Testing
- Questionnaire
- Where
- Italy
- Volunteers
- 282 people
- Sponsor
- IRCCS Policlinico S. Donato
Depressive Symptoms, Clinical Depression
Improving Mood in Assisted Living Settings
Late-life depression levels are escalating, and include 24% of all tenants of Assisted Living (AL) settings. A promising, novel intervention is a computerized visual speed of processing training program known as Road Tour.
- Trial name
- NCT01763216
- Testing
- Road Tour, Boatload of Crosswords
- Where
- 32 sites in United States
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- Marianne Smith
Depression Chronic, Depressed
Evaluation of Dalia Solution For Depressed Patient
The goal of this superiority clinical investigation, prospective, multicenter, controlled, randomized, open-label is to evaluate the clinical impact of the Dalia medical telemonitoring device on the management of depressive…
- Conditions
- Depression Chronic, Depressed, Depressed Mood, Depression and Quality of Life
- Trial name
- DaliaMonitorin (NCT07211984)
- Testing
- Dalia Monitoring, Conventional healthcare
- Where
- France
- Volunteers
- 644 people
- Sponsor
- Dalia Care
Stroke Recurrence, Cardiovascular Events
Post-stroke Depression Treatment Effect on Stroke Recurrence
It is not clear whether depresssion can predispose, or precipitate stroke recurrence in patients with stroke. We sought the relationship of post stroke depression with stroke recurrence.
- Conditions
- Stroke Recurrence, Cardiovascular Events, Depression
- Trial name
- STROKE (NCT04776226)
- Testing
- Citalopram
- Where
- Turkey (Türkiye)
- Volunteers
- 1,230 people
- Sponsor
- Ege University
Cardiovascular Diseases, Hypertension
Impact of Sleep Disordered Breathing in Older Adults
To test the hypothesis that clinically inapparent sleep-disordered breathing was associated with blood pressure elevation, impairment of health-related quality of life, and depression.
- Conditions
- Cardiovascular Diseases, Hypertension, Depression, Sleep Apnea Syndromes
- Trial name
- NCT00005378
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Major Depression, Sleep
Sleep TMS for Depression
The goal of this study is to establish the feasibility, tolerability, and preliminary efficacy of sleep-state transcranial magnetic stimulation (TMS) for enhancing plasticity in depression treatment.
- Trial name
- NCT06824415
- Testing
- TMS
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Stanford University
Anxiety, Intensive Care Unit Syndrome
Virtual Reality to Reduce the Anxiety in Critically Ill Patient
Anxiety and discomfort generated by repeated medical cares and invasive procedures can induce cognitive disorders in critical illness survivors as post-traumatic stress disorder.
- Trial name
- VRAI (NCT06747793)
- Testing
- Virtual Reality
- Where
- France
- Volunteers
- 128 people
- Sponsor
- University Hospital, Toulouse
Major Depressive Diorder
RCT of Psilocybin-assisted CBT for Depression
The primary objectives of this clinical investigation are to (1) determine the acceptability and feasibility of joining psilocybin-assisted therapy with cognitive-behavioral therapy (PA-CBT) for patients with depression, (2)…
- Trial name
- NCT07281352
- Testing
- Psilocybin (drug), cognitive behavioral therapy, Minimal supportive therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Los Angeles
Postoperative Complications, Respiratory Depression
Comparison of Remimazolam and Propofol in Endoscopic Examinations and Treatments
This study aims to evaluate the efficacy and safety of Remimazolam, either used alone or in combination with Propofol, for moderate sedation anesthesia during endoscopic therapies or examinations.
- Conditions
- Postoperative Complications, Respiratory Depression, Postoperative Nausea, Vomiting
- Trial name
- Remimazolam (NCT06777758)
- Testing
- Remimazolam, Propofol
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Colorectal Cancer
Clinical Study of Dexmedetomidine Administered Intranasally to Relieve Perioperative Anxiety and Depression in Patients With Colorectal Tumors
Currently, domestic and international research on dexmedetomidine as well as anxiety and depression is more focused on basic research.
- Trial name
- NCT06139926
- Testing
- Dexmedetomidine administered intranasally
- Where
- China
- Volunteers
- 126 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Depression
[18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET
Background: Major depressive disorder (MDD) is a psychiatric condition. People with MDD have occasional bouts of depressive symptoms; these bouts are called major depressive episodes (MDEs).
- Trial name
- NCT05703685
- Testing
- Lung scan, Apremilast, 18F-PF-06445974
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Multiple Sclerosis (MS), Unipolar Depression
Mood Disorders in Multiple Sclerosis Patients
This study investigates the frequency of unipolar and bipolar mood disorders in patients with multiple sclerosis. MS is a chronic condition that affects the central nervous system, and previous research suggests that mood…
- Conditions
- Multiple Sclerosis (MS), Unipolar Depression, Bipolar Disorder, Mood Disorders
- Trial name
- MSMD (NCT06652308)
- Where
- China
- Volunteers
- 85 people
- Sponsor
- Islamic Azad University, Sanandaj
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