Clinical trials: Depth of Anaesthesia
Neuropathic Pain, Phantom Limb Pain
Mechanisms and Treatment of Post-amputation Neuropathic Pain
Phantom and residual limb pain are types of peripheral neuropathic pain that are difficult to treat and where the underlying mechanisms are still not fully understood.
- Conditions
- Neuropathic Pain, Phantom Limb Pain, Amputation
- Trial name
- NCT04819503
- Testing
- Spinal anaesthesia (sub-study 1), Repetitive transcranial magnetic stimulation (sub-study 2)
- Where
- Norway
- Volunteers
- 1 people
- Sponsor
- Oslo University Hospital
Anesthesia, Child
Performance Evaluation of the Depth of Anesthesia Monitors in Pediatric Surgery
The purpose of this study is to determine how Bispectral index (BIS) and Entropy EEG monitors agree between themselves and with end-tidal concentration of sevoflurane (ETsevo) in relationship with the age in the pediatric surgery…
- Trial name
- NCT02240368
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Foggia
Intraoperative Monitoring, Depth of Anesthesia
The Clinical Research of Needle Electrodes Used in Bispectral Index to Monitor the Depth of Anesthesia
In this study, the EEG information of patients was collected by different BIS electrodes, in order to compare the quality of EEG signals obtained by subdermal needle electrodes and the original BIS sensors, and try to use…
- Trial name
- NCT05130333
- Testing
- No intervention
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Anesthesia
Effect of Subanaesthetic Dose of Ketamine on Depth of Anaesthesia Consistency
General Anaesthesia (GA) is a medical state of controlled unconsciousness that inhibits two dimensions of consciousness: the content and the level of consciousness.
- Trial name
- NCT06986109
- Testing
- Ketamine, Propofol
- Where
- India
- Volunteers
- 106 people
- Sponsor
- Sir Ganga Ram Hospital
Elderly, Surgery
Anesthesia Maintenance With Target-controlled Infusion of Propofol and Remifentanil at Fixed Ratio
The impact of anesthesia depths on early postoperative neurocognitive complications after total intravenous anesthesia (TIVA) remains controversial.
- Conditions
- Elderly, Surgery, Depth of Anesthesia, Total Intravenous Anesthesia
- Trial name
- NCT07479719
- Testing
- Light anesthesia, Deep anesthesia
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Anesthesia
Bispectral Index (BIS) Values Required for an Adequate Depth of Anesthesia in Elderly Patients Using Propofol
A correlation between the bispectral index values and electroencephalographic patterns at the loss of consciousness (LOC) when using propofol in elderly patients, has not been determined.
- Trial name
- NCT03195530
- Testing
- Propofol
- Where
- Chile
- Volunteers
- 12 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Anesthesia
Validation of a Multimodal Indicator of Depth of Anesthesia
The present study is designed to validate an multimodal indicator of anesthetic depth (Schneider G et al. 2014, Anesthesiology 120, 819-28). The indicator previously developed shall now be tested on an independent set of data.
- Trial name
- NCT02742012
- Testing
- the study is observational
- Where
- 3 sites in Germany
- Volunteers
- 257 people
- Sponsor
- Technical University of Munich
Neurosurgical Intervention
Study of the Link Between the Slope of the Photomotor Reflex and the Depth of Anesthesia: "ILLUMINANS" Study
Pupillary diameter monitoring is currently used routinely for assessment of the nociception / antinociception balance during surgery. Pupillary diameter decreases reflexively in response to light flash, called photomotor reflex.
- Trial name
- ILLUMINANS (NCT03867955)
- Testing
- Collection of datas
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Parkinson's Disease
Sub-thalamic Nucleus Stimulation in Parkinson Disease
Deep brain stimulation (DBS) is an established procedure for the symptomatic treatment of Parkinson's disease. This procedure performed in two steps using electrophysiology.
- Trial name
- PARKEO (NCT01817088)
- Testing
- New targeting procedure without electrophysiology, Classical neurosurgical procedure
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Bordeaux
Monitoring of Depth of Anesthesia
Patient Positioning and Its Influence on BIS, NOL, and Cerebral Oxygenation in Anesthetized Patients
The goal of this observational study is to find out how changes in body position during surgery might affect brain monitoring results in patients who are under general anesthesia.The main question it aims to answer is: Does…
- Trial name
- NCT07013734
- Volunteers
- 71 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Somatosensory Evoked Potentials, and Electroencephalography
SEP Changes During Deep Anesthesia
The relation between burst and suppression periods in transcranial and direct cortical recorded EEG with cortical amplitudes median nerve somatosensory evoked potentials is studied.
- Trial name
- SEPinBSP (NCT02394002)
- Testing
- Propofol
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Andrea Szelenyi
Hallux Valgus (Bunions)
Liposome Bupivacaine for ANKLE Blocks
Postoperative analgesia for hallux valgus surgery (bunionectomy) is inconsistent and may even result in rebound pain when the (ankle) blocks wear off.
- Trial name
- NCT03106545
- Testing
- Liposome bupivacaine
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Catherine Vandepitte, M.D.
Deep Brain Stimulation Surgery, Electrophysiology
Analysis of Deep Brain Nuclei LFP and Cortical EEG Signals During the Recovery From General Anesthesia
The correlations of deep brain nuclei firing and cerebral cortex activity during recovery from general anesthesia is unclear. In this study, the local field potential (LFP) from the deep brain nuclei and the scalp…
- Conditions
- Deep Brain Stimulation Surgery, Electrophysiology, General Anesthesia, Consciousness, Loss of
- Trial name
- NCT06400901
- Testing
- No interventions
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Ruijin Hospital
Postoperative Pain, Hip Osteoarthritis
Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blocks for Hip Surgery Analgesia
This study aims to investigate the efficacy of adding a Posterior Pericapsular Deep gluteal block to two other standard nerve blocks-the Pericapsular Nerve Group block and the Lateral Femoral Cutaneous Nerve block-for patients…
- Conditions
- Postoperative Pain, Hip Osteoarthritis, Hip Fractures
- Trial name
- NCT07531030
- Testing
- Posterior Pericapsular Deep Gluteal, Pericapsular Nerve Group, and Lateral Femoral Cutaneous Nerve Blocks., Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blocks.
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Anesthesia
Does Adding Magnesium Sulphate to Low Dose Rocuronium Affects Depth of Blockade
This study aim is to compare the effect of magnesium sulphate combined with low dose rocuronium versus standard dose rocuronium
- Trial name
- NCT04510337
- Testing
- standard rocuronium dose, Magnesium sulfate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute, Egypt
Laparoscopic Hysterectomy
Effect of Trendelenburg Position on Patient State Index
The goal of this observational study is to evaluate whether the Trendelenburg position affects electroencephalography-based depth of anesthesia monitoring and cerebral oxygenation during general anesthesia.
- Trial name
- NCT07467200
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sakarya University
Thoracic Anesthesia
Height-based Formula for Predicting the Insertion Depth of Left-sided Double and the Role of Fiberoptic Bronchoscopy
The use of height based formula to predict insertion depth of left-sided double lumen tube in thoracic surgery is now well established. The investigators have developed a formula to be used and published recently.
- Trial name
- NCT04449770
- Testing
- double lumen tube
- Where
- Saudi Arabia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- King Saud University
Monitoring of Depth of Anesthesia, AAI Index
Monitoring of Adequate Course of General Anesthesia
Clinical monitoring is the most common method of adjustment of the appropriate level of general anesthesia. However, the episodes of intraoperative awareness are still reported, suggesting that clinical observations may not be…
- Trial name
- MoDA (NCT03331692)
- Testing
- monitoring of the proper level of general anesthesia
- Where
- Poland
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Military Institute od Medicine National Research Institute
Postoperative Cognitive Dysfunction
Relationship Between Sleep EEG, Intraoperative EEG and Postoperative Cognitive Dysfunction
The challenge of new recommendations and better adapted practices is pushing to operate patients who are getting older and more fragile.
- Trial name
- SOMEDYSPO (NCT04481347)
- Testing
- Sleep EEG recording using a DREEM® headband, Montreal Cognitive Assessment (MoCA), Intraoperative EEG recording using a Sedline® monitoring
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Propofol Adverse Reaction
Propofol Induction Based on Lean Body Weight on the Depth of Anesthesia
Propofol has significant hemodynamic side effects. It is a lipophilic agent and is generally used at a dose of 2-2.5 mg/kg for induction.
- Trial name
- propofol (NCT06862349)
- Testing
- Group T received propofol at a dose of 2-2.5 mg/kg based on total body weight, Group L received propofol at 2-2,5mg/kg dose based on lean body weight, which was calculated from CT imaging by a radiologist.
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara City Hospital Bilkent