Clinical trials: Depth of Anaesthesia
Pain Management, Sedation
The Effect of Continuous Femoral Nerve Block With Modulation of Depth of Anesthesia on Prognosis of Patients Receiving Total Knee Arthroplasty
The interaction of analgesia and sedation ot their effect on the prognosis of surgical patients still need to be elucidated.Currently, how to optimize intra-operative Analgesia and sedation to improve the prognosis of surgical…
- Conditions
- Pain Management, Sedation, Peripheral Nerve Block, Total Knee Arthroplasty
- Trial name
- NCT02576015
- Testing
- peri-operative continuous femoral nerve block with light sedation, post-operative continuous femoral nerve block, lidocaine
- Where
- China
- Volunteers
- 380 people
- Sponsor
- Min Su
Surgery Requiring Spinal Anesthesia
Validation of Phase Lag Entropy(PLE) as an Indicator of Depth of Sedation in Patients Undergoing Spinal Anesthesia
For verifying the phase lag entropy as the tool for measurement of level of consciousness, the investigators compared phase lag entropy to bispectral index.
- Trial name
- NCT03319004
- Testing
- apply phase lag entropy sensor
- Where
- South Korea
- Volunteers
- 27 people
- Sponsor
- Gangnam Severance Hospital
Coil Treatment, Deep Sedation
What Should be the Anesthesia Method in Endobronchial Coil Treatment
This prospective, randomize study was conducted in a university hospital. Bronchoscopic lung volume reduction (BLVR) coil treatment has recently been introduced into clinical practice as an alternative for patients chronic…
- Trial name
- NCT03652324
- Testing
- method
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- TC Erciyes University
Depth of Anaesthesia
Quantifying Nitrous Oxide Effect on Depth of Anaesthesia Using Theoretically Based Time Series Modelling
Our hypothesis is that a new method of depth of anaesthesia monitoring, using theoretically based time series modelling will result in improved ability to determine nitrous oxide anaesthetic effect
- Trial name
- NCT00226837
- Testing
- Nitrous oxide
- Where
- 2 sites in Australia
- Volunteers
- 60 people
- Sponsor
- Melbourne Health
Brain Tumor Adult, Processed EEG
Processed EEG for Monitoring of Anesthetic Depth in Intracranial Tumor Surgery
An important feature of neurosurgical anesthesia is early postoperative recovery of consciousness with minimal residual sedation.
- Conditions
- Brain Tumor Adult, Processed EEG, Total Intravenous Anesthesia
- Trial name
- NCT06922500
- Testing
- depth of anesthesia
- Where
- Sweden
- Volunteers
- 126 people
- Sponsor
- Region Skane
Hip Fracture Surgery
Predicted Level of General Anaesthesia in Hip Fracture Surgery
The purpose of this study is to evaluate if prediction of general anaesthesia level by the Smartpilot® View device can improve the quality of anaesthesia in patients undergoing hip fracture surgery.
- Trial name
- NAPfem (NCT02556658)
- Testing
- General anesthesia managed by the Smartpilot® View, General anesthesia managed without the Smartpilot® View
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers
Anesthesia, Brain Tumor, Supratentorial,Outcome
Study of the Depth of Anesthesia on Postoperative Clinical Outcome in Patients With Supratentorial Tumor
Recent studies have shown that deep anesthesia is associated with poor outcome. There is still lack of randomized controlled trials with large sample size on the effect of depth of anesthesia on the postoperative outcomes in…
- Trial name
- DEPTH (NCT03033693)
- Testing
- Bispectral index will be targeted at 50, Bispectral index will be targeted at 35
- Where
- China
- Volunteers
- 1,461 people
- Sponsor
- Beijing Tiantan Hospital
Anesthesia
Validation of a Multimodal Indicator of Depth of Anesthesia
The present study is designed to validate an multimodal indicator of anesthetic depth (Schneider G et al. 2014, Anesthesiology 120, 819-28). The indicator previously developed shall now be tested on an independent set of data.
- Trial name
- NCT02742012
- Testing
- the study is observational
- Where
- 3 sites in Germany
- Volunteers
- 257 people
- Sponsor
- Technical University of Munich
Airway Complication of Anesthesia
Impact of Labor and Delivery on Ultrasound Measured Cricothyroid Membrane Depth and Height
The cricothyroid membrane acts as a route through which the upper airway can be accessed to provide oxygen and ventilation to patients.
- Trial name
- NCT04546087
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Retinoblastoma
Cardio-respiratory Events During Ophthalmic Artery Chemotherapy for Retinoblastoma Under a Deep Anesthesia
Background: Serious adverse cardio-respiratory events (SCRE) occur during super selective ophthalmic artery chemotherapy for retinoblastoma in children.
- Trial name
- NCT02764398
- Volunteers
- 32 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Cesarean Section (MeSH: D002585), Anesthesia
Evaluation of Consciousness Depth (qCON) and Analgesia Depth (qNOX) Indices in General Anesthesia
Objective: This prospective, single-center, observational clinical study aims to evaluate changes in qCON (hypnotic depth), qNOX (nociception/analgesia depth), EMG, and other parameters in patients undergoing elective cesarean…
- Conditions
- Cesarean Section (MeSH: D002585), Anesthesia, Intraoperative Awareness, Analgesia
- Trial name
- NCT07887919
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Kudret Dogru
Analgesia, Pain, Postoperative
Comparison of Erector Spinae Block and Combined Deep and Superficial Serratus Anterior Plane Block
Objective: The authors hypothesized that combined deep and superficial serratus anterior plane block (SAPB) is as effective as erector spinae plane block (ESPB) for intraoperative and postoperative analgesia for video-assisted…
- Conditions
- Analgesia, Pain, Postoperative, Thoracic, Anesthesia
- Trial name
- NCT06073197
- Testing
- erector spinae plane block, combined deep and superficial serratus anterior plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Uludag University
Parkinsons Disease
Anesthesia for Deep Brain Stimulation
Deep brain stimulation for the treatment of Parkinson's disease has unique surgical stages and anesthesia needs. In the first stage the electrodes are inserted in the targeted brain areas and in the second stage the pulse…
- Trial name
- NCT01789385
- Testing
- Dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Diskapi Teaching and Research Hospital
Parkinson's Disease
DBS Under General Anesthesia: Comparison To The Standard Technique
There is a growing trend in functional neurosurgery toward direct anatomical targeting for deep brain stimulation (DBS). This study describes a method and reports the initial experience placing DBS electrodes under general…
- Trial name
- NCT01997398
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Deep Sedations, Conscious Sedation
Comparison of Safety and Efficacy for Different Sedation Regimens During Colonoscopy
This is a randomized, double-blinded, prospective study which will be conducted at the Department of Gastroenterology, King Saud Hospital, Unaizah, Qassim, Saudi Arabia.
- Conditions
- Deep Sedations, Conscious Sedation, Colonoscopy
- Trial name
- NCT06763705
- Testing
- Midazolam, Propofol, Fentanyl
- Where
- Saudi Arabia
- Volunteers
- 183 people
- Sponsor
- Qassim Health Cluster
Neuromuscular Blockade
Pharmacokinetics of Rocuronium for Deep Block (DeepRocu)
Rocuronium is a non-depolarising neuromuscular blocking agent. The compound has a rapid onset and an intermediate duration of action.
- Trial name
- DeepRocu (NCT03545308)
- Testing
- Rocuronium
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Pain
Evaluate the Depth and Duration of Anesthesia
The purpose of the study is to determine the depth (mm) of anesthesia provided by the Synera topical patch (using sensory depth and pain depth evaluations), and to determine the duration (minutes) of anesthesia provided by the…
- Trial name
- NCT00891163
- Testing
- Synera™ Topical Patch (70 mg lidocaine/70 mg tetracaine)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- ZARS Pharma Inc.
Acute Ischemic Stroke
Prognostic Prediction Model of Patients With AcUte Stroke undeRgoing EndOvascular TheRApy (AURORA)
Stroke is the leading cause of disability-adjusted life years (DALYs) in China, imposing a heavy burden on society and families.
- Trial name
- AURORA (NCT06009315)
- Where
- China
- Volunteers
- 949 people
- Sponsor
- Beijing Tiantan Hospital
Elective Surgeries, General Anesthesia
Validation of the PRST Score Against Bispectral Index
The goal of this randomized controlled trial is to evaluate whether the PRST (Evans) score is a valid method for monitoring the depth of general anesthesia in adult surgical patients.
- Conditions
- Elective Surgeries, General Anesthesia, BIS
- Trial name
- NCT07590388
- Testing
- PRST Monitoring, PRST + BIS Monitoring
- Where
- Indonesia
- Volunteers
- 183 people
- Sponsor
- Gadjah Mada University
Sleep Apnea, Obstructive, Anesthesia
Pilot Study : New Sensors to Monitor Apnea During Sedation
Evaluation of a Mandibular and Abdominal Motion Detection Sensor (JAWAC) to Prevent Apnea During Sedation With Propofol in TCI Mode
- Trial name
- JAWAC (NCT02909309)
- Testing
- JAWAC system + Capnoline + Spo2
- Where
- Belgium
- Volunteers
- 21 people
- Sponsor
- Erasme University Hospital