Clinical trials: Depth of Anaesthesia
Geriatric Patient Care Improvement, Postoperative Delirium (POD)
The Effects of Anesthesia Depth Monitoring on Postoperative Recovery and Cognitive Functions in the Geriatric Patient Population
This study will be conducted on patients aged 65 and older scheduled for surgery due to lumbar or cervical disc herniation. General anesthesia is routinely used for these types of surgeries in the hospital.
- Conditions
- Geriatric Patient Care Improvement, Postoperative Delirium (POD), Burst Suppression
- Trial name
- NCT06844279
- Testing
- Control Group: Standard Hemodynamic Monitoring, Processed Electroencephalogram (BIS Index), Processed Electroencephalogram (DSA Mode)
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Aslıhan Güleç
Depth of Anesthesia Monitoring
The Alternative Position for the SedLine® Sensor
SedLine® Brain Function Monitoring provides real-time insight into a patient's depth of anesthesia with bilateral data acquisition and processing of electroencephalogram (EEG) signals.
- Trial name
- NCT03947060
- Where
- United Arab Emirates
- Volunteers
- 40 people
- Sponsor
- Cleveland Clinic Abu Dhabi
Airway Complication of Anesthesia, Respiratory Complications of Care
Comparison of Deep Versus Awake Tracheal Extubation in Adults
Prospective, randomized, single-blinded controlled study to compare the airway and respiratory complications of deep and awake tracheal extubations in adults.
- Trial name
- CDATE (NCT05361850)
- Testing
- Extubation
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- United States Navy
Thoracic Anesthesia
Height-based Formula for Predicting the Insertion Depth of Left-sided Double and the Role of Fiberoptic Bronchoscopy
The use of height based formula to predict insertion depth of left-sided double lumen tube in thoracic surgery is now well established. The investigators have developed a formula to be used and published recently.
- Trial name
- NCT04449770
- Testing
- double lumen tube
- Where
- Saudi Arabia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- King Saud University
Parkinson's Disease
DBS Under General Anesthesia: Comparison To The Standard Technique
There is a growing trend in functional neurosurgery toward direct anatomical targeting for deep brain stimulation (DBS). This study describes a method and reports the initial experience placing DBS electrodes under general…
- Trial name
- NCT01997398
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Deep Caries, Molar Incisor Hypomineralisation
Comparison of Intraosseous Anaesthesia Using a Computerized System (QuickSleeper) to Conventional Anesthesia
The purpose is to compare the efficacy of an intraosseous anaesthesia using a computerized system (QuickSleeper) to a conventional infiltration anesthesia.
- Trial name
- QUICK (NCT02084433)
- Testing
- intraosseous anaesthesia using a computerized system, conventional anasthesia
- Where
- France
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anesthesia, Sedation and Analgesia
Prospective IR-led Sedation Feasibility
This study wants to see if some interventional radiology (IR) procedures can be done without using general anesthesia. General anesthesia needs a lot of staff and equipment. It can also cause side effects.
- Conditions
- Anesthesia, Sedation and Analgesia, Interventional Radiology
- Trial name
- NCT07443254
- Testing
- ketamine, Fentanyl (IV), Midazolam
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- CAMC Health System
Deep Inferior Epigastric Artery Perforator Flap Breast Reconstruction
The Effect of Volatile Anesthesia and Total Intravenous Anesthesia on Shedding of the Endothelial Glycocalyx in Patients Undergoing Mastectomy and Breast Reconstruction Using Deep Inferior Epigastric Artery Perforator Free Flap
The aim of this study was to investigate the effects of total intravenous and inhalation anesthesia on the damage of endothelial glucocorticoids by comparing the concentration of syndecan-1 in patients undergoing mastectomy and…
- Trial name
- NCT05136508
- Testing
- Propofol, Sevoflurane
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Sedation, Anesthesia, Spinal
Bispectral Index(BIS) on Depth of Sedation With Dexmedetomidine, Propofol and Midazolam During Spinal Anesthesia
This study is to investigate on the objective relevance between bispectral index (BIS) and Observer's assessment of alertness/sedation (OAA/S) scale in patients sedated with Midazolam, propofol and dexmedetomidine during spinal…
- Trial name
- BIS (NCT03399019)
- Testing
- Dexmedetomidine, Propofol, Midazolam
- Where
- South Korea
- Volunteers
- 45 people
- Sponsor
- Hallym University Medical Center
The Focus is to Develop a Closed-loop Control System for Anaesthesia in Vitroretinal Surgery, Surgery Due to Expansive Processes in Head, and Long-term Sedation
Modeling and Closed-loop Control of Depth of Anaesthesia
The study evaluates the effect of anaesthetic agents to depth of anaesthesia. An improved PK-PD model wil be developed that will provide the basis for understanding the mechanisms, simulating various scenarios and developing…
- Trial name
- NCT03569839
- Testing
- Propofol
- Where
- Slovenia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Brain Tumor Adult, Processed EEG
Processed EEG for Monitoring of Anesthetic Depth in Intracranial Tumor Surgery
An important feature of neurosurgical anesthesia is early postoperative recovery of consciousness with minimal residual sedation.
- Conditions
- Brain Tumor Adult, Processed EEG, Total Intravenous Anesthesia
- Trial name
- NCT06922500
- Testing
- depth of anesthesia
- Where
- Sweden
- Volunteers
- 126 people
- Sponsor
- Region Skane
Parkinson Disease, Dystonia
Neurophysiological Characteristics of Subthalamic Deep-brain Stimulation (STN-DBS)
The intraoperative neuroelectrophysiological signals were collected from patients undergoing STN-DBS under general anesthesia in the Neurosurgery Department of Wuhan union Hospital, and their preoperative conditions and…
- Trial name
- NCT04707638
- Testing
- No intervention used
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Sore Throat
Effect of Intraoperative Muscle Relaxation Depth on Postoperative Sore Throat and Hoarseness After General Anesthesia
Investigators assess and compare postoperative sore throat and hoarseness in the group maintaining moderate relaxation and deep relaxation during operation.
- Trial name
- NCT03391700
- Testing
- Rocuronium(deep), Rocuronium(moderate)
- Where
- South Korea
- Volunteers
- 206 people
- Sponsor
- SMG-SNU Boramae Medical Center
Healthy
Evaluation of the Depth and Duration of Anesthesia From Heated Lidocaine/Tetracaine (Synera®) Patches Compared With 5% Lidocaine (Lidoderm®) Patches Applied to Healthy Adult Volunteers
This will be a randomized, single-blind, active-controlled, two-period crossover study in adult volunteers to compare the duration and depth of anesthesia between Synera® and Lidoderm® patches when applied for 30 minutes and 4…
- Trial name
- NCT01688518
- Testing
- Heated Lidocaine/Tetracaine Patch, 5% Lidocaine Patch
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- CRI Lifetree
Observation of Neuromuscular Block, Complication of Ventilation Therapy
Deep Neuromuscular Block During General Anaesthesia in Robotic Surgery
The aim of this project is to show, whether the use of the deep neuromuscular block in certain laparoscopic robot-assisted surgery can positively influence main physiological functions compared to the use of standard…
- Conditions
- Observation of Neuromuscular Block, Complication of Ventilation Therapy, Postoperative Recovery
- Trial name
- NCT03420937
- Testing
- Sugammadex, Neostigmine, Atropin Biotika
- Where
- Czechia
- Volunteers
- 138 people
- Sponsor
- University Hospital Olomouc
Elderly, Surgery
Anesthesia Maintenance With Target-controlled Infusion of Propofol and Remifentanil at Fixed Ratio
The impact of anesthesia depths on early postoperative neurocognitive complications after total intravenous anesthesia (TIVA) remains controversial.
- Conditions
- Elderly, Surgery, Depth of Anesthesia, Total Intravenous Anesthesia
- Trial name
- NCT07479719
- Testing
- Light anesthesia, Deep anesthesia
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Anesthesia
Effect of Subanaesthetic Dose of Ketamine on Depth of Anaesthesia Consistency
General Anaesthesia (GA) is a medical state of controlled unconsciousness that inhibits two dimensions of consciousness: the content and the level of consciousness.
- Trial name
- NCT06986109
- Testing
- Ketamine, Propofol
- Where
- India
- Volunteers
- 106 people
- Sponsor
- Sir Ganga Ram Hospital
Low Flow Anesthesia
Low-Flow Anesthesia Without Wash-in: Effects on Oxygenation and Depth of Anesthesia
This study aims to evaluate whether adjusting the fresh gas flow rate to low-flow immediately after intubation, without performing a wash-in, is a reliable approach with respect to depth of anesthesia and oxygenation.
- Trial name
- NCT07534839
- Testing
- Initiation of low-flow anesthesia without wash-in following intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Erzincan Binali Yildirim Universitesi
Anesthesia, Child
Performance Evaluation of the Depth of Anesthesia Monitors in Pediatric Surgery
The purpose of this study is to determine how Bispectral index (BIS) and Entropy EEG monitors agree between themselves and with end-tidal concentration of sevoflurane (ETsevo) in relationship with the age in the pediatric surgery…
- Trial name
- NCT02240368
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Foggia
Atrial Fibrillation, Atrial Flutter
Comparison of Bolus Dosing of Methohexital and Propofol in Elective Direct Current Cardioversion
A randomized, open-blinded, prospective study to evaluate the timeliness and safety of direct current cardioversion (DCCV) when using methohexital when compared to the more often used propofol.
- Trial name
- NCT04187196
- Testing
- Propofol, Methohexital
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Wake Forest University Health Sciences