Clinical trials: Dermal Atrophy
Labia Majora Atrophy and Hypotrophy
Evaluation of the Efficacy and Safety of the Dermal Filler for Augmentation of Labia Majora.
The study is an open-label uncontrolled single-center study for the evaluation of the Performance characteristics (efficacy and safety) of the dermal filler "MMI-22-04-2019" on the female genital area for the aesthetic…
- Trial name
- NCT04652817
- Testing
- MMI-22-04-2019
- Where
- Bulgaria
- Volunteers
- 35 people
- Sponsor
- Mesoestetic Pharma Group S.L.
Alveolar Bone Loss
Increase of Peri-implant Soft Tissues With Screw or Membrane
The objective of this observational study is to evaluate the growth of peri-implant soft tissues using an heterologous dermal membrane graft (group A) or a 2 mm healing screw used as a vertical support of the limbs (group B)…
- Trial name
- DERMA (NCT03358667)
- Testing
- augmentation peri-implant soft tissue
- Where
- Italy
- Volunteers
- 84 people
- Sponsor
- International Piezosurgery Academy
Parkinson Disease, Multiple System Atrophy
Synuclein-One Study
The Synuclein-One Study will be evaluating α-synuclein in patients with Parkinson's disease, Multiple System Atrophy, Dementia with Lewy bodies and Pure Autonomic Failure.
- Conditions
- Parkinson Disease, Multiple System Atrophy, Dementia With Lewy Bodies, Pure Autonomic Failure
- Trial name
- NCT04700722
- Testing
- Skin Biopsy
- Where
- 23 sites in United States
- Volunteers
- 428 people
- Sponsor
- CND Life Sciences
Atrophic Vaginitis, Vaginal Diseases
Evaluation of Gynecological Acceptability of a Health Care Product
The research will be conducted with a product for use in the intimate region in up to 75 research participants who will use the investigational product for 28 ± 2 days.
- Trial name
- NCT04247022
- Testing
- Health care product (intimate gel)
- Where
- Brazil
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Herbarium Laboratorio Botanico Ltda
Skin Tissue Diseases, Connective Tissue Diseases
A Clinical Trial to Assess the Potential of LEO 130852A Gel to Reduce Steroid Induced Skin Atrophy on Healthy Skin
The purpose of this study is to assess the effect of LEO 130852A gel 1% in maintaining skin thickness in healthy skin treated with steroid.
- Trial name
- NCT02392130
- Testing
- Clobetasol propionate 0.05% ointment, LEO 130852A gel 1%
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- LEO Pharma
Vaginal Atrophy, Vulvovaginal Signs and Symptoms
Evaluation of the Efficacy and Safety of the Dermal Filler for Female Intimate Area Hydration and Atrophy of the Vagina.
The study is an open-label uncontrolled single-center study for the evaluation of the Performance characteristics (efficacy and safety) of the dermal filler "MMG-23-04-2019" on the female genital area for the medicinal…
- Conditions
- Vaginal Atrophy, Vulvovaginal Signs and Symptoms, Dyspareunia, Urinary Incontinence
- Trial name
- NCT04659668
- Testing
- MMG-23-04-2019
- Where
- Bulgaria
- Volunteers
- 37 people
- Sponsor
- Mesoestetic Pharma Group S.L.
Gingival Recession
Evaluation of Subepithelial Connective Tissue Graft Versus Acellular Dermal Matrix With Tunnel Technique in Treatment of Multiple Gingival Recessions
The goal of the present study is to compare the amount of root coverage resulting from subepithelial connective tissue graft and acellular dermal matrix associated with tunnel technique among patients suffering from multiple…
- Trial name
- NCT02916186
- Testing
- Acellular Dermal Matrix, Tunnel technique with the subepithelial connective tissue graft
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
To Compare Two Commonly Used Soft Tissue Grafting Techniques to Achieve Coronal Flap Advancement and Root Coverage
This study will compare two incision designs to allow for coronal gingival/mucosal flap advancement and tissue augmentation with acellular dermal matrix (ADM) graft around teeth with gingival recession and a lack of adequate…
- Trial name
- VISTA (NCT03566108)
- Testing
- VISTA, STA
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Recession, Gingival
Root Coverage With Acellular Dermal Matrix and Bovine Derived Osseous
The study will consist of a randomized controlled clinical study trial comparing the results of coronally positioned flap with AlloDerm GBR plus bovine derived xenograft versus coronally positioned tunnel with AlloDerm GBR plus…
- Trial name
- NCT03582995
- Testing
- Flap Surgery for root coverage with Alloderm and xenograft, Tunnel Surgery for root coverage with Alloderm and xenograft
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Atrophy, Hemifacial, Elastosis
A Clinical Trial Evaluating the Efficacy of a Skin Cream in Improving Facial Appearance and Skin Elasticity
A Clinical Trial Evaluating Efficacy of a Skin Cream Targeting Dermal Fat in Improving the Skin Elasticity of Healthy Volunteers.
- Conditions
- Atrophy, Hemifacial, Elastosis, Photoaging
- Trial name
- NCT04769193
- Testing
- Adipeau face cream
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Adipeau Inc.
Gingival Recession
Study of Root Coverage With Acellular Dermal Matrix: Puros® Dermis Versus Alloderm®
The purpose of the study is to evaluate whether clinical parameters for Puros Dermis are, at minimum, equivalent when compared to AlloDerm, the current industry standard, for the treatment of single, non-adjacent Miller's Class I…
- Trial name
- NCT00881959
- Testing
- Puros® Dermis versus Alloderm®
- Where
- 4 sites in United States
- Volunteers
- 80 people
- Sponsor
- Zimmer Biomet
Cortico Atrophy
Physiopathological Study and Pharmacological Modulation of Cutaneous Atrophy's Markers Induced by Glucocorticoids
Methodology :Phase III study, single centre, double blind, versus excipient, randomised, controlateral design. Selection of the patients :Number of subjects required 60 : 30 patients needing an oral corticotherapy 30 patients…
- Trial name
- NCT00709579
- Testing
- RV3391A
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
Gingival Recession
Treatment of Gingival Recession Defects Using Platelet-Rich Fibrin With an Allogenic Dermal Matrix
The study aims to test the non-inferiority of an Allogenic Dermal Matrix with Platelet-Rich Fibrin for treatment of gingival recessions in comparison to the Connective Tissue Graft.
- Trial name
- NCT05819515
- Testing
- Tunneled coronally advanced flap
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Gingival Recession, Generalized, Graft Reaction
The Healing of Soft Tissue Augmentation by Acellular Dermal Matrix and Autogenous Subepithelial Connective Tissue Graft
The study team proposes to prospectively compare the healing outcomes of autogenous soft tissue connective tissue graft (CTG) and Acellular dermis matrix (ADM) in a split-mouth design study for patients requiring modification of…
- Trial name
- NCT03954028
- Testing
- Gingival Punch Biopsy after healing of Gingival Soft Tissue Augmentation
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Gingival Recession, Gingival Diseases
Comparation Between Two Surgical Techniques With Acellular Dermal Matrix in Treatment of Gingival Recessions
The gold standard for the treatment of gingival recession, is the coronal repositioning of the flap associated with the subepithelial connective tissue graft.
- Conditions
- Gingival Recession, Gingival Diseases, Mouth Diseases, Periodontal Atrophy
- Trial name
- NCT02774967
- Testing
- root coverage
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo