Clinical trials: Dermal Filler
Dermal Filler, Hyaluronic Acid
China Post-Market Clinical Follow-up of FACILLE®
The results showed that subjects tolerated the Sodium Hyaluronate Gel for Injection (FACILLE®) well, with no systemic AEs, SAEs, and unanticipated AEs and associated with high satisfaction and self-evaluated effectiveness.
- Conditions
- Dermal Filler, Hyaluronic Acid, Nasolabial Fold
- Trial name
- NCT05294562
- Volunteers
- 1,552 people, healthy volunteers welcome
- Sponsor
- SciVision Biotech Inc.
Facial Wrinkles
Safety and Effectiveness of Belotero® in Subjects With Fitzpatrick Phototypes IV Through VI
This is a study to assess how safe and effective an investigational product, Belotero® is in people with all skin types with facial wrinkles, such as nasolabial folds.
- Trial name
- NCT00922623
- Testing
- Belotero®
- Where
- 3 sites in United States
- Volunteers
- 93 people
- Sponsor
- Merz North America, Inc.
Nasolabial Folds
To Evaluate the Efficacy and Safety of 'BRDE33-100' for the Temporary Correction of Moderate to Severe Nasolabial Folds
This study aims to demonstrate the non-inferiority of BRDE33-100 to Soonsoofill in temporarily improving moderate to severe nasolabial folds.
- Trial name
- NCT07069920
- Testing
- BRDE33-100, Soonsoofill
- Where
- South Korea
- Volunteers
- 128 people
- Sponsor
- BRPharm Co., Ltd.
Infra-orbital Hollows, Tear-trough Deformity
RHA® Redensity Eye Versus No-treatment for the Infra-Orbital Hollows
This is a multicenter, blinded evaluator, randomized, prospective, no treatment control clinical study to identify whether RHA® Redensity Eye (*) is superior to no treatment for the correction of moderate to severe tissue volume…
- Conditions
- Infra-orbital Hollows, Tear-trough Deformity, Wrinkle
- Trial name
- NCT04577898
- Testing
- RHA® Redensity Eye
- Where
- 4 sites in United States
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Nasolabial Folds
Evaluate Efficacy, Safety & Subject Satisfaction of Pain Management With Pliaglis® Cream for Dermal Filler Injections
Pliaglis® Cream versus compounded topical anesthetic for pain management during Restylane® injections for the correction of nasolabial folds.
- Trial name
- NCT00716443
- Testing
- tetracaine 7% / lidocaine 7% cream (Pliaglis® Cream), benzocaine 20% / lidocaine 6% / tetracaine 4% ointment
- Where
- 4 sites in United States
- Volunteers
- 51 people
- Sponsor
- Galderma R&D
Nasolabial Fold
Post Market Clinical Follow up Evaluating the Performance and Safety of Juläine(TM) on Nasolabial Fold Wrinkles
The goal of this post marketing study is to verify clincal performance and safety of CE-marked device Juläine. The main objective is to evaluate device performance when used as intended for augmentation of shallow to deep…
- Trial name
- NCT06471933
- Testing
- Juläine
- Where
- 2 sites in Spain, Sweden
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Nordberg Medical AB
Aesthetics
Long Term Safety and Efficacy Assessment of Hyaluronic Acid Dermal Filler With for the Treatment of Nasolabial Folds
This study evaluates the injection of a hyaluronic acid dermal filler with lidocaine 0.3% in the treatment of nasolabial folds (NLF).
- Trial name
- ECLAH (NCT02703740)
- Testing
- Hyaluronic acid dermal filler with lidocaine 0.3%
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Laboratoires Genévrier
Dermal Fillers, Nasolabial Folds, Wrinkles
Purpose of This Study is the Demonstration of Safety and Efficacy of the Dermal Fillers DXP01 Temporary Improvement of Moderate to Severe Nasolabial Folds
Purpose of this study is the demonstration of safety and efficacy of the dermal fillers DXP01 Face for restoration of moderate to severe nasolabial folds
- Trial name
- DXP01 (NCT06885775)
- Testing
- DXP01, Juvederm ULTRA 3
- Where
- Romania
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- DEXLEVO
Nasolabial Fold Correction
Evaluation of Efficacy and Safety of Intella Dermal Filler in Moderate to Severe Nasolabial Folds
This single-arm, before-and-after clinical trial evaluated the safety and efficacy of Intella, a combined CaHA and HA dermal filler manufactured by Espad Pharmed Darou Co., for the correction of moderate to severe nasolabial…
- Trial name
- NCT07102537
- Testing
- Hyaluronic acid combined with calcium hydroxyapatite injection
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Espad Pharmed
Lip Augmentation
A Study to Evaluate the Safety and Performance of Dr Korman Laboratories' Hyaluronic Acid Filler 20 mg/mL With Lidocaine for Lip Augmentation
This study will assess the safety and effectiveness of a dermal filler called DKL crosslinked hyaluronic acid 20 mg/mL with lidocaine 0.3% when injected into the lips of healthy men and women who want to have fuller lips.
- Trial name
- NCT07204691
- Testing
- DKL crosslinked sodium hyaluronate 20 mg/mL + Lidocaine 0.3% dermal filler
- Where
- 2 sites in Sweden
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Dr. Korman Laboratories Ltd.
Facial Wrinkles
Evaluation of the Safety and Efficacy of CosmetaLife™ for the Correction of Nasolabial Folds
This is a randomized, double-blind pivotal study to evaluate the safety and effectiveness of CosmetaLife injectable dermal filler for the correction of wrinkles and folds, such as nasolabial folds (i.e., smile lines).
- Trial name
- NCT00414544
- Testing
- CosmetaLife, Restylane
- Where
- 5 sites in United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Cosmeta
Skin Aging, Skin Wrinkling
Evaluation of the Safety and Performance Characteristics of Mesofiller Aox for the Correction of Mild and Moderate Facial Wrinkles.
The investigation is a single centre, interventional, prospective, non-randomized, open-label, uncontrolled, single arm, un-blinded investigation for evaluation of safety and performance of the medical device M-AOX-2021 in the…
- Trial name
- NCT06486740
- Testing
- mesofiller aox
- Where
- Bulgaria
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Mesoestetic Pharma Group S.L.
Aging, Premature
Safety and Performance of DKL Crosslinked Sodium Hyaluronate 23 Dermal Filler for Improvement of NLF Appearance
This is a pivotal, prospective active-controlled, randomized, double blinded (blinded evaluator and subject), intra-individual split-face comparison, non-inferiority study of DKL crosslinked sodium hyaluronate 23 versus Juvederm…
- Trial name
- NCT05021913
- Testing
- DKL crosslinked sodium hyaluronate 23, Juvéderm Volift™ with lidocaine (Allergan, Inc)
- Where
- Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dr. Korman Laboratories Ltd.
Hyaluronic Acid, Dermal Fillers
Clinical Trial of Cross-linked Hyaluronic Acid Dermal Filler
The goal of this clinical trial is to evaluate the safety and efficacy of Formaderm Young Dermal Filler Injection, which is a hyaluronic acid dermal filler injected into the mid to deep dermis for the correction of…
- Trial name
- NCT05935501
- Testing
- Formaderm Young, Restylane
- Where
- 2 sites in China
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Maxigen Biotech Inc.
Signs of Facial Aging With Volume Loss in the Upper Cheeks, Nasolabial Folds and Marionette Lines
Safety, Effectiveness and Participant Satisfaction Study of a Dermal Filler (of RADIESSE® (+) Lidocaine) in the Treatment of Ageing Signs in the Face
The primary objective is to collect clinical data to confirm performance and safety for RADIESSE® (+) Lidocaine, when used in accordance with its labelling in the treatment of nasolabial folds, marionette lines and/or upper cheek…
- Trial name
- RaLido (NCT03650387)
- Testing
- RADIESSE® (+) Lidocaine
- Where
- 7 sites in Germany
- Volunteers
- 207 people
- Sponsor
- Merz North America, Inc.
Dermal Fillers, Lidocaine
The Clinical Trial of Difference Between Formaderm Lidocaine and Formaderm Dermal Filler Injection
The goal of this clinical trial is to evaluate the safety and efficacy of Formaderm Lidocaine to the correction of nasolabial folds wrinkle and reduction of pain immediately after treatment.
- Conditions
- Dermal Fillers, Lidocaine, Hyaluronic Acid
- Trial name
- NCT05935449
- Testing
- Formaderm Lidocaine, Formaderm Dermal Filler Injection
- Where
- 2 sites in Taiwan
- Volunteers
- 42 people
- Sponsor
- Maxigen Biotech Inc.
Aging, Chin Retrusion
Safety and Effectiveness Evaluation of TEOSYAL® TPVM Versus COMPARATOR for the Remodeling of the Lower Face
The clinical study is designed to prospectively evaluate the safety and effectiveness of TEOSYAL® TPVM when compared to COMPARATOR for the remodeling of the lower face
- Trial name
- LIFTUP (NCT05986630)
- Testing
- TEOSYAL® TPVM, COMPARATOR
- Where
- Switzerland
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Lips Enhancement, Perioral Wrinkles
Evaluation of Facial HA Dermal Fillers in Real-Life Conditions
The goal of this post-market interventional study is to confirm, under real-life conditions, the safety and performance of hyaluronic acid-based dermal fillers intended to modify skin anatomy and facial appearance.
- Conditions
- Lips Enhancement, Perioral Wrinkles, Nasolabial Fold Wrinkles, Cheek Augmentation
- Trial name
- NCT07255261
- Testing
- Facial injection of hyaluronic acid-based dermal fillers.
- Where
- 8 sites in France
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Symatese
Nasolabial Folds, Wrinkles
TEOSYAL® RHA Ultra Deep and Perlane-L® for the Correction of Nasolabial Folds
The purpose of this study is to compare the effectiveness and safety of TEOSYAL® RHA Ultra Deep versus Perlane-L® in the treatment of moderate to severe nasolabial folds.
- Trial name
- NCT02253147
- Testing
- TEOSYAL® RHA Ultra Deep
- Where
- 4 sites in United States
- Volunteers
- 140 people
- Sponsor
- Teoxane SA
Dermal Fillers, Cheek Augmentation
Evaluation of Performance and Safety of Injectable KIO017 Device Range for Facial Tissue Filling
The goal of this clinical trial is to primarily evaluate the performance of KIO017 in filling/volumizing after injection in different areas in healthy women or men, older than 18 years and seeking an improvement of her/his face…
- Conditions
- Dermal Fillers, Cheek Augmentation, Lip Augmentation, Perioral Rhytids
- Trial name
- LITCHEE (NCT06872359)
- Testing
- KIO017-1, KIO017-2, KIO017-3
- Where
- 3 sites in France, Poland
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Kiomed Pharma