Clinical trials: Dermal Filler
Facial Wrinkles
Multicenter Study of the Safety and Efficacy of Dermal Filler, Belotero® Soft
This study is to determine the safety and effectiveness of Belotero® Soft compared to active comparator in the correction of mild facial wrinkles, such as nasolabial folds.
- Trial name
- NCT00877279
- Testing
- CosmoDerm1, Belotero Soft
- Where
- 5 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Nasolabial Fold
Evaluation of Collagen Dermal Filler With Lidocaine for the Correction of Nasolabial Folds
Evaluation the efficacy and safety of collagen dermal filler with lidocaine using in the middle to deep dermis for the correction of nasolabial folds.
- Trial name
- NCT03844529
- Testing
- Sunmax FULLSGEN with Lidocaine
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Pain
S-Caine™ Peel (Skin Numbing Cream) to Treat Pain During Skin Filler Injection in the Face
Injection of dermal filler is used as an aesthetic treatment to fill in unwanted wrinkles and scars. There can be substantial pain associated with dermal filler injections.
- Trial name
- NCT00110760
- Testing
- S-Caine™ Peel (lidocaine and tetracaine cream 7%/7%)
- Where
- 3 sites in United States
- Volunteers
- 70 people
- Sponsor
- ZARS Pharma Inc.
Aging Hands
Evaluation of Radiesse® Dermal Filler for Hand Rejuvenation
The purpose of this study is to assess the safety and effectiveness of Radiesse® Injectable Dermal Filler for hand treatment.
- Trial name
- NCT01004107
- Testing
- Radiesse Injectable Dermal Filler
- Where
- 4 sites in Germany
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Moderate to Severe Nasolabial Fold
Safety and Performance of PTMC Dermal Filler
The goal of this clinical trial is to assess the safety and performance of the PTMC Dermal filler for treating moderate to severe nasolabial folds in adult men and women.
- Trial name
- NCT06316479
- Testing
- PTMC Dermal Filler
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Aqpha Medical B.V.
Lip
Four Hyaluronic Acid Fillers for Lip Augmentation
There is need for evidence-based and reproducible data comparing the safety, longevity and patient satisfaction propensity of the various HA soft tissue filler products.
- Trial name
- NCT04362891
- Testing
- Cosmetic lip augmentation
- Where
- 4 sites in Netherlands
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Photoaging
Investigating Age Dependence of Fibroblast and Extracellular Matrix Responses to Cross-linked Hyaluronic Acid Filler in Human Skin
The purpose of the study is to investigate the impact of the injection of dermal filler on the quality of the skin dermal extracellular matrix in persons between the ages of 30-50 years.
- Trial name
- NCT06195605
- Testing
- Restylane-L, Vehicle
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Michigan
Perioral Rhytids, Aging
RHA Redensity - Perioral Rhytids
Randomized, blinded, No-Treatment control, multi-center, prospective clinical study, to identify whether TEOSYAL RHA® Redensity is more effective than No-Treatment in the correction of moderate to severe dynamic perioral rhytids…
- Conditions
- Perioral Rhytids, Aging, Wrinkle
- Trial name
- NCT03092219
- Testing
- TEOSYAL RHA Redensity
- Where
- 8 sites in United States, Canada
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Facial Wrinkles
Multicenter Study of the Safety and Effectiveness of Dermal Filler, Belotero®.
This was a study to find out how an investigational product, Belotero, compares to a second product in people with facial wrinkles, such as nasolabial folds.
- Trial name
- NCT00876265
- Testing
- Belotero, Zyplast
- Where
- 6 sites in United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Wrinkles Such as Nasolabial Folds
Evaluate the Efficacy and Safety of Lidocaine-Containing Hyaluronic Acid Filler in the Treatment of Nasolabial Folds.
The purpose of this study is to evaluate the efficacy and safety of PavéDerm J-fill soft dermal filler vs. Restylane® Lyft lidocaine in the treatment of moderate to severe nasolabial folds.
- Trial name
- NCT05040594
- Testing
- PavéDerm J-Fill Soft Dermal Filler, Restylane® Lyft Lidocaine
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yung Shin Pharm. Ind. Co., Ltd.
Mid Face Volume Deficit
THIODERM STRONG Compared to Juvéderm® VOLUMA® Lidocaine for the Treatment of Midface Volume Deficit
This mono-center clinical investigation is intended to evaluate the safety and effectiveness of THIODERM STRONG (test device) in the correction of moderate to severe midface volume deficit compared to Juvéderm® VOLUMA® Lidocaine…
- Trial name
- TIMI (NCT06128109)
- Testing
- Thioderm Strong, Juvéderm VOLUMA Lidocaine
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Croma-Pharma GmbH
Nasolabial Folds
Safety and Effectiveness of ELLANSÉ®-S Dermal Filler in the Treatment of Nasolabial Folds
The study will be a prospective, randomized, multi-center, split-face, controlled, double-blind clinical trial to evaluate the safety and effectiveness of ELLANSÉ®-S for the treatment of NLFs.
- Trial name
- NCT06984835
- Testing
- Ellanse S, Calcium Hydroxylapatite-based filler
- Where
- 7 sites in United States
- Volunteers
- 126 people
- Sponsor
- AQTIS Medical B.V.
Nasolabial Folds, Wrinkles
TEOSYAL® RHA Global Action, TEOSYAL® RHA Deep Lines, and Juvéderm® Ultra XC for the Correction of Nasolabial Folds
The purpose of this study is 1) to compare the effectiveness and safety of TEOSYAL® RHA Global Action versus Juvéderm® Ultra XC, and 2) to compare the effectiveness and safety of TEOSYAL® RHA Deep Lines versus Juvéderm® Ultra XC…
- Trial name
- NCT02195427
- Testing
- TEOSYAL® RHA Global Action, TEOSYAL® RHA Deep Lines
- Where
- 5 sites in United States
- Volunteers
- 148 people
- Sponsor
- Teoxane SA
Wrinkles
Post Market Non-Interventional Study of Safety and Performance of RefillHA Volume
This study designed to evaluate the safety and performance of RefillHA Volume, a dermal filler for facial soft tissue augmentation and correction of facial wrinkles and folds in routine clinical setting.
- Trial name
- NCT07329608
- Where
- Israel
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Glyance
Aging
EVOLENCE® Assessment of Recovery Time and Impact of Dermal Filler Selection: The E-ART™ Study
The purpose of this study is to gather information about the immediate effects and recovery time for treatment with EVOLENCE/EVOLENCE BREEZE for soft tissue augmentation.
- Trial name
- NCT00911872
- Testing
- collagen (EVOLENCE)
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Solish, Nowell, M.D.
Pain, Aging
RHA® Redensity With New Anesthetic Agent Perioral Rhytids (PAS)
This is a randomized, controlled, double-blinded, within-subject (split-face), multicenter, prospective study to investigate whether RHA® Redensity with new anesthetic agent is non-inferior to RHA® Redensity with lidocaine in…
- Trial name
- NCT06378086
- Testing
- RHA® Redensity with new anesthetic agent, RHA® Redensity with lidocaine
- Where
- 3 sites in United States, Puerto Rico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Facial Rejuvenation
Pilot Trial to Assess the Performance and Tolerance of mRDX-02-17 Dermal Filler in the Facial Rejuvenation
mRDX-02-17 is a device for facial beauty care composed of hyaluronic acid in a concentration of 1.5% (p/v), as a functional ingredient, recommended for the correction and treatment of wrinkles and dermal depressions.
- Trial name
- NCT03537456
- Testing
- mRDX-02-17
- Where
- 2 sites in Romania
- Volunteers
- 39 people
- Sponsor
- Mesoestetic Pharma Group S.L.
Skin Aging, Skin Wrinkling
Efficacy and Performance Evaluation of mGlobal L+AS 20 mg/ml Hyaluronic Acid, for the Correction of Light to Moderate Wrinkles and Folds
The investigation is a single-centre, interventional, prospective, non-randomized, open-label, uncontrolled, single-arm, un-blinded investigation for evaluation of the safety and performance of the product mGlobal L+AS for…
- Trial name
- M-GLO-LS (NCT06482723)
- Testing
- mGlobal L+AS
- Where
- Bulgaria
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Mesoestetic Pharma Group S.L.
Dermal Filler, Hyaluronic Acid
China Post-Market Clinical Follow-up of FACILLE®
The results showed that subjects tolerated the Sodium Hyaluronate Gel for Injection (FACILLE®) well, with no systemic AEs, SAEs, and unanticipated AEs and associated with high satisfaction and self-evaluated effectiveness.
- Conditions
- Dermal Filler, Hyaluronic Acid, Nasolabial Fold
- Trial name
- NCT05294562
- Volunteers
- 1,552 people, healthy volunteers welcome
- Sponsor
- SciVision Biotech Inc.
Facial Wrinkles
Safety and Effectiveness of Belotero® in Subjects With Fitzpatrick Phototypes IV Through VI
This is a study to assess how safe and effective an investigational product, Belotero® is in people with all skin types with facial wrinkles, such as nasolabial folds.
- Trial name
- NCT00922623
- Testing
- Belotero®
- Where
- 3 sites in United States
- Volunteers
- 93 people
- Sponsor
- Merz North America, Inc.