Clinical trials: Dermatitis, Exfoliative
Netherton Syndrome
Study of Skin and Gut Microbiome in a Skin Condition Involving Skin Barrier Impairment and Allergic Symptoms: Netherton Syndrome
It is proposed to conduct an exploratory study to analyze the skin, intestinal, and salivary microbiome, as well as the skin mycobiome and virome, of patients (adolescents and young adults) with Netherton syndrome, a condition…
- Trial name
- DERMABIOTE (NCT07280091)
- Testing
- Superficial skin swabs, Stool samples, Saliva samples
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Darier Disease, Hailey-Hailey Disease
National Registry for Ichthyosis and Related Disorders
The ichthyoses are a family of genetic skin diseases characterized by dry, thickened, scaling skin. Dermatologists estimate that there are over twenty varieties of ichthyosis, with a wide range of severity and associated…
- Conditions
- Darier Disease, Hailey-Hailey Disease, Hyperkeratosis, Epidermolytic, Ichthyosis
- Trial name
- NCT00074685
- Where
- United States
- Volunteers
- 610 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Netherton Syndrome
Open Label, Safety and Efficacy Study of QRX003 Lotion in Subjects With Netherton Syndrome
To assess the safety, tolerability, and efficacy of QRX003 lotion (4%) when added to standard of care treatment regimen, including systemic therapy in subjects with Netherton syndrome
- Trial name
- NCT05789056
- Testing
- QRX003, 4% Lotion
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- Quoin Pharmaceuticals
Mycosis Fungicides, Sezary Syndrome
Killer Immunoglobulin-Like Receptor Transcripts Expression for the Diagnosis of Epidermotropic Cutaneous T Cell Lymphoma
The most frequent cutaneous T-cell lymphomas (CTCL) are mycosis fungoid and Sezary syndrome. The diagnosis of these lymphomas is difficult using current methods, especially because numerous benign dermatological conditions can…
- Conditions
- Mycosis Fungicides, Sezary Syndrome, Dermatitis, Dermatitis, Exfoliative
- Trial name
- KIR (NCT00748319)
- Testing
- Detection of KIR receptor by RT PCR
- Where
- France
- Volunteers
- 495 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Netherton Syndrome
Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome
The goal of this clinical trial (via an expanded access Treatment Protocol) is to learn if QRX003 (an investigational drug) applied topically to the skin (including up to the entire body [except the scalp]) works to treat the…
- Trial name
- NCT06953466
- Testing
- QRX003, 4% Lotion
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Quoin Pharmaceuticals
Pityriasis Rubra Pilaris
A Pilot Study of Alefacept for the Treatment of Pityriasis Rubra Pilaris
The purpose of this study is to determine whether the biologic medication alefacept (Amevive) is effective and safe in the treatment of Pityriasis Rubra Pilaris.
- Trial name
- NCT00815633
- Testing
- Alefacept
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Joshua Zeichner
Child Syndrome
Study of Metabolic Modifications in Children With Noonan Syndrome
Noonan syndrome (NS) is a rare genetic disease (incidence 1/2500 live births) characterized by the association of craniofacial manifestations, cardiopathies, short stature, and tumor predisposition.
- Trial name
- MetabNoonan (NCT02383316)
- Testing
- Oral Glucose tolerance test
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Toulouse
Genetic Skin Disease, Keratosis Follicularis
Study of Scaling Disorders and Other Inherited Skin Diseases
The purpose of this study is to identify the genes responsible for certain scaling disorders and other inherited skin diseases and to learn about the medical problems they cause.
- Conditions
- Genetic Skin Disease, Keratosis Follicularis, Lamellar Ichthyosis
- Trial name
- NCT00001292
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)