Clinical trials: Dermatitis
Xerosis Due to Atopic Dermatitis
Xerosis and Use of Topical Moisturizer
The primary hypothesis is that routine measurement of trans epidermal water loss (TEWL) rates and stratum corneum (SC) hydration levels will promote patient adherence to maintenance moisturizer therapy and prevent disease…
- Trial name
- NCT04341623
- Testing
- Cetaphil Pro Eczema moisturizer, Electronic interaction, GPSkin
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Wake Forest University Health Sciences
Toxic Epidermal Necrolysis, Immunotherapy
New Therapeutic Target for Toxic Epidermal Necrolysis (TEN) Using Anti-CD38+ Monoclonal Antibodies.
Toxic Epidermal Necrolysis (TEN) are rare diseases that are dermatologic emergencies characterized by widespread epidermal necrosis and sloughing of skin. A hundred patients are affected each year in France.
- Conditions
- Toxic Epidermal Necrolysis, Immunotherapy, Cutaneous Adverse Drug Reactions (CADR)
- Trial name
- NET-CD38 (NCT07110662)
- Testing
- DARATUMUMAB (DARZALEX®)
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Hospices Civils de Lyon
Radiodermatitis; Acute, Radiotherapy Side Effect
The Use of Photobiomodulation in the Management of Radiodermatitis in Patients in Palliative Care. A Prospective Study.
It is estimated that there will be 670,000 new cases of cancer worldwide in 2020-2022 and it is known that the most commonly instituted treatments in cancer are chemotherapy, radiotherapy and surgery.
- Conditions
- Radiodermatitis; Acute, Radiotherapy Side Effect, Cancer Patients, Palliative Care
- Trial name
- NCT05561803
- Testing
- Photobiomodulation Therapy
- Where
- Brazil
- Sponsor
- University of Nove de Julho
Dermatitis
A Placebo Controlled 4 Week Proof of Concept Study With 0.5% Roflumilast Cream in Patients With Mild Atopic Dermatitis (RO-2351-001-EM)
The aim of this proof of concept study is to show the safety and efficacy of 0.5 % dermal roflumilast cream in the treatment of atopic dermatitis in adults.
- Trial name
- NCT00746382
- Testing
- Roflumilast cream
- Sponsor
- AstraZeneca
Occupational Diseases
Hazardous Substances Injuries
This clinical study aims to evaluate the effectiveness and safety of [intervention or treatment] in patients with [clinical condition].
- Trial name
- Substances (NCT07879261)
- Testing
- Retrospective Administrative Data Assessment
- Where
- Israel
- Volunteers
- 1,951 people
- Sponsor
- Sergio Gabriel Susmallian
Head and Neck Tumor, Breast Cancer
Topical Diclofenac for Prevention of Radiation-induced Dermatitis
Radiation induced dermatitis (RID) is one of the leading adverse events of radiation therapy, and if occurred could alter the course of therapy.
- Trial name
- NCT06905561
- Testing
- Diclofenac Sodium Gel
- Where
- China
- Volunteers
- 156 people
- Sponsor
- The Second Affiliated Hospital of Hainan Medical University
Dermatitis, Atopic
Study of Autologous Total Immunoglobulin G Therapy for Atopic Dermatitis
This is a randomized, double-blind, placebo-controlled parallel group study on the efficacy and safety of intramuscular injections of autologous immunoglobulin in patients with moderate-to-severe atopic dermatitis.
- Trial name
- NCT02835170
- Testing
- Autologous immunoglobulin
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Ajou University School of Medicine
Atopic Dermatitis
A Phase II, Placebo-controlled Trial Evaluating the Efficacy of Antroquinonol in Patients With Atopic Dermatitis
Primary Objective: To evaluate the activity of Antroquinonol in patients with atopic dermatitis. Secondary Objective: To assess the mechanism and cytokines change of Antroquinonol in patients with atopic dermatitis.
- Trial name
- NCT04110873
- Testing
- Antroquinonol Capsule 50mg, Antroquinonol Capsule 100mg
- Where
- Taiwan
- Volunteers
- 14 people
- Sponsor
- Chung Shan Medical University
Atopic Dermatitis (AD)
Effectiveness of Psychodermatologic Educational Modules on Atopic Dermatitis Patient Outcomes
In a previous part of this study, we created educational modules about the psychodermatology of inflammatory skin conditions, with a particular emphasis on atopic dermatitis, for patients.
- Trial name
- NCT07009483
- Testing
- Patient education modules providing information on the psychological aspects of atopic dermatitis treatment and management.
- Where
- 3 sites in Canada
- Volunteers
- 57 people
- Sponsor
- University of Alberta
Palmar-plantar Erythrodysesthesia
Topical Antiperspirant for Hand-Foot Syndrome
The objectives of this study are to evaluate the effectiveness of an antiperspirant in preventing or attenuating the severity of palmer-plantar erythrodysesthesia associated with the Food and Drug Administration (FDA)-approved…
- Trial name
- NCT00213993
- Testing
- antiperspirant
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Wisconsin, Madison
Infant Formula
Growth, Allergy and Neurodevelopment in Infants on Hydrolysed Formula
Breastfeeding is the recommended diet for all infants during the first half of infancy and is associated with numerous health benefits.
- Trial name
- GRANDIOSA (NCT05578716)
- Testing
- Partially hydrolysed formula
- Where
- 2 sites in Sweden
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Umeå University
Atopic Dermatitis, Moderate-to-severe Atopic Dermatitis
A Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of IMG-007 in Adults With Atopic Dermatitis (AD)
The primary objective of this study is to evaluate the safety of IMG-007 in adults with moderate-to-severe AD. The secondary objectives are to evaluate the pharmacokinetics and efficacy of IMG-007 in AD patients.
- Conditions
- Atopic Dermatitis, Moderate-to-severe Atopic Dermatitis, AD
- Trial name
- NCT05984784
- Testing
- IMG-007
- Where
- 12 sites in United States, Canada
- Volunteers
- 13 people
- Sponsor
- Inmagene LLC
Atopic Eczema
A Longitudinal Investigation of Skin Barrier Development From Birth and the Validation of Early Predictors of Atopic Eczema Risk: the Skin Testing for Atopic Eczema Risk (STAR) Study
Eczema is a chronic disease of the skin that is becoming more common worldwide for reasons unknown. Currently the best indicator that a baby will suffer from eczema is if either or both parents have the condition, although this…
- Trial name
- STAR (NCT03143504)
- Testing
- Skin Testing for Atopic eczema
- Where
- United Kingdom
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Atopic Dermatitis
Short Term Growth in Children With Atopic Dermatitis
Main objective:to assess short term growth in children with atopic dermatitis during treatment with tacrolimus 0.1% and mometasone furoate 0.1%. A singl blind randomised cross over trial including 20 children.
- Trial name
- NCT00236106
- Testing
- tacrolimus ointment 0.1%, mometasone furoate 0.1%
- Volunteers
- 20 people
- Sponsor
- Children´s Clinic, Randers
Atopic Dermatitis
Efficacy and Tolerability of a Probiotic Ointment
This study evaluates the tolerability and efficacy of a probiotic ointment compared with a comparator lotion in children with atopic dermatitis.
- Trial name
- NCT07701447
- Testing
- Probiotic Ointment, Comparator product
- Volunteers
- 92 people
- Sponsor
- BioGaia AB
Seborrhea, Seborrheic Dermatitis
Efficacy and Safety of Low-dose Oral Isotretinoin for Seborrhea
Oral isotretinoin is the gold standard drug to treat moderate to severe acne. Other indications like seborrhea, seborrheic dermatitis have been suggested.
- Conditions
- Seborrhea, Seborrheic Dermatitis, Quality of Life
- Trial name
- NCT01139749
- Testing
- oral isotretinoin, salicylic acid and ciclopirox olamine
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Breast Cancer
Evaluating Mepitel in Post-mastectomy Patients and the Role of the Skin Microbiome in Radiation Dermatitis
The aim of this study is to examine alterations in the skin microbiome that occur during radiation therapy. The study design will examine changes secondary to ionizing radiation, and correlate these changes with the development…
- Trial name
- NCT03519438
- Testing
- Mepitel
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Atopic Dermatitis
Prevention of Development of Transcutaneous Sensitization in Children With Atopic Dermatitis During Their First Year of Life
This experimental non-randomized clinical study is aimed at comparing the efficacy and safety assessment of the proposed topical therapy algorithms with the use of topical calcineurin inhibitors in reducing the severity of atopic…
- Trial name
- NCT04900948
- Testing
- Pimecrolimus cream 1%, cream 0.1% methylprednisolone aceponate
- Where
- Russia
- Volunteers
- 108 people
- Sponsor
- National Medical Research Center for Children's Health, Russian Federation
Atopic Dermatitis
Phase III Clinical Study of VC005 in Adult and Adolescents With Mild to Moderate Atopic Dermatitis
A multicenter, randomized, double-blind, vehicle controlled phase III clinical study to evaluate the efficacy and safety of VC005 in adults and adolescents with mild to moderate atopic dermatitis
- Trial name
- NCT07592585
- Testing
- VC005
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Jiangsu vcare pharmaceutical technology co., LTD
Atopic Dermatitis
Study of TDM-180935 in Atopic Dermatitis Patients
Randomized, Vehicle-controlled, Parallel Group Study of TDM-180935 in Atopic Dermatitis Patients
- Trial name
- NCT06363461
- Testing
- TDM-180935 topical ointment 1.0%, TDM-180935 topical ointment 2.0%, TDM-180935 topical vehicle ointment 1
- Where
- 7 sites in United States
- Volunteers
- 24 people
- Sponsor
- Technoderma Medicines Inc.