Clinical trials: Dermatitis Hand
Chronic Hand Eczema
Efficacy and Safety of Delgocitinib Cream in Adolescents 12-17 Years of Age With Moderate to Severe Chronic Hand Eczema
The purpose of this trial is to test if delgocitinib cream is effective in treating chronic hand eczema (CHE) and to find out what side effects it may have compared with a cream vehicle with no active medical ingredient in…
- Trial name
- DELTA TEEN (NCT05355818)
- Testing
- Delgocitinib, Cream vehicle
- Where
- 37 sites in Australia, Belgium and 5 more
- Volunteers
- 98 people
- Sponsor
- LEO Pharma
Hand Eczema
A Randomised Trial of a Moisturising Cream in Preventing Recurrence of Hand Eczema
The purpose of this study is to investigate whether a moisturizing cream can prevent hand eczema.Patients with previous hand eczema will be studied.
- Trial name
- NCT00576550
- Testing
- Urea, betamethasone valerate
- Where
- 3 sites in Norway
- Volunteers
- 53 people
- Sponsor
- ACO Hud Nordic AB
Chronic Hand Dermatitis
Pimecrolimus Cream 1% in Patients (18 Years of Age and Over) With Mild to Moderate Chronic Hand Dermatitis
Topical steroids are standard of care for Chronic Hand Dermatitis, but long-term use is associated with adverse effects. This study will assess the efficacy and safety of pimecrolimus cream 1% in patients with mild-to-moderate…
- Trial name
- NCT00226707
- Testing
- Pimecrolimus Cream 1%
- Volunteers
- 652 people
- Sponsor
- Novartis
Chronic Hand Eczema
Phase 2b Dose-ranging Trial to Evaluate Delgocitinib Cream 1, 3, 8, and 20 mg/g Compared to Delgocitinib Cream Vehicle Over a 16-week Treatment Period in Adult Subjects With Chronic Hand Eczema
The purpose of this research trial was to test different strengths of a new trial medication, delgocitinib cream 1, 3, 8, and 20 mg/g, and to investigate how treatment with delgocitinib cream affects chronic hand eczema.
- Trial name
- NCT03683719
- Testing
- Delgocitinib cream, Delgocitinib cream vehicle
- Where
- 28 sites in United States, Denmark and 1 more
- Volunteers
- 258 people
- Sponsor
- LEO Pharma
Chronic Hand Eczema
Pharmacokinetics of Delgocitinib 20 mg/g Cream in Subjects With Chronic Hand Eczema
The purpose of the trial is to test how much delgocitinib enters the body over a given time period after application of delgocitinib cream in patients with moderate to severe hand eczema.
- Trial name
- NCT05486117
- Testing
- Delgocitinib
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- LEO Pharma
Hand Eczema
Topical Ruxolitinib Evaluation in Chronic Hand Eczema Study 1
The purpose of this study is to evaluate the efficacy and safety of ruxolitinib cream in adult participants with diagnosis of chronic hand eczema (CHE) and moderate to severe disease activity (Investigator's Global Assessement…
- Trial name
- TRuE-CHE1 (NCT05219864)
- Testing
- Ruxolitinib cream, Vehicle
- Where
- 49 sites in United States, Canada and 4 more
- Sponsor
- Incyte Corporation
Chronic Hand Eczema
Efficacy and Safety of Delgocitinib Cream in Adults With Moderate to Severe Chronic Hand Eczema
This was a 16-week study in adult participants with chronic hand eczema (CHE). > The participants visited the clinic regularly to have the study doctor assess their CHE and to answer questions about itch, pain, CHE symptoms, and…
- Trial name
- DELTA 1 (NCT04871711)
- Testing
- Delgocitinib cream, Cream vehicle
- Where
- 54 sites in Canada, France and 4 more
- Volunteers
- 487 people
- Sponsor
- LEO Pharma
Dermatitis, Chronic
Ethanol-Free Clobetasol Propionate Foam 0.05% (Olux-E Foam) vs Vehicle Foam in the Treatment of Chronic Hand Dermatitis.
The purpose of this study is to determine how clobetasol proprionate foam works against a placebo foam in the treatment of hand dermatitis.
- Trial name
- NCT01323673
- Testing
- clobetasol propionate 0.05%
- Where
- 10 sites in United States
- Volunteers
- 125 people
- Sponsor
- Stiefel, a GSK Company
Palmar-Plantar Erythrodysesthesia, Breast Cancer
Study of 0.1% Uracil Topical Cream (UTC) for the Prevention of Hand-Foot Syndrome
The purpose of this research study is to see if combining uracil cream (UTC) with capecitabine (Xeloda) can prevent Hand-Foot Syndrome.
- Trial name
- NCT01100463
- Testing
- Cream, 0.1% Uracil Cream
- Where
- 6 sites in United States
- Volunteers
- 18 people
- Sponsor
- Nanometics (d.b.a. PHD Biosciences)
Hand Eczema
LEO19123 Cream in the Treatment of Hand Eczema
To compare the efficacy and safety of two different dose combinations of LEO19123 cream (calcipotriol and LEO80122) with LEO19123 cream vehicle for 3 weeks in the treatment of patients with hand eczema.
- Trial name
- NCT00404196
- Testing
- Calcipotriol and LEO80122 (LEO19123 cream)
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- LEO Pharma
Chronic Hand Eczema (CHE)
Topical Ruxolitinib Evaluation in Chronic Hand Eczema Study 2
The purpose of this study is to evaluate the efficacy and safety of ruxolitinib cream in adult participants with diagnosis of chronic hand eczema (CHE) and moderate to severe disease activity (Investigator's Global Assessement…
- Trial name
- TRuE-CHE2 (NCT05233410)
- Testing
- Ruxolitinib cream, Vehicle
- Where
- 39 sites in United States, Bulgaria and 5 more
- Sponsor
- Incyte Corporation
Eczema, Hand Eczema
A Study to Assess CLn® BodyWash for Reducing Skin Fauna in Patients With Hand Eczema
The primary objective of this protocol is to acquire pilot data for a larger study to test the following hypothesis: Treatment of the hands of patients with chronic hand dermatitis/atopic dermatitis with CLn BodyWash, a novel gel…
- Conditions
- Eczema, Hand Eczema, Atopic Dermatitis
- Trial name
- NCT01826630
- Testing
- CLn BodyWash, Cetaphil Daily Facial Cleanser
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Shari L Hand
Chronic Hand Eczema
Efficacy and Safety of Delgocitinib Cream in Adults With Moderate to Severe Chronic Hand Eczema (DELTA 2)
This was a 16-week study in adult participants with chronic hand eczema (CHE). The participants visited the clinic regularly to have the study doctor assess their CHE and to answer questions about itch, pain, CHE symptoms, and…
- Trial name
- DELTA 2 (NCT04872101)
- Testing
- Delgocitinib cream, Cream vehicle
- Where
- 50 sites in Belgium, Canada and 5 more
- Volunteers
- 473 people
- Sponsor
- LEO Pharma
Atopic Dermatitis, Atopic Hand Eczema
A 32-week Trial to Evaluate the Efficacy and Safety of Tralokinumab in Subjects With Moderate-to-severe Atopic Hand Eczema Who Are Candidates for Systemic Therapy
The purpose of this study is to test if treatment with tralokinumab is safe and efficacious in treating moderate-to-severe atopic hand eczema.
- Trial name
- ADHAND (NCT05958407)
- Testing
- Tralokinumab
- Where
- 69 sites in United States, Belgium and 8 more
- Volunteers
- 235 people
- Sponsor
- LEO Pharma
Chronic Hand Dermatitis
Comparison Study With E-DO in Chronic Hand Dermatitis
The objective of this study is to evaluate the topical E-DO in patients with Chronic Hand Dermatitis (fu kuei shou).
- Trial name
- NCT00556855
- Testing
- E-DO
- Where
- Taiwan
- Volunteers
- 67 people
- Sponsor
- HenKan Pharmaceutical Co., Ltd.
Hand Dermatosis
Study to Evaluate Safety, Efficacy and Tolerability of Clobetasol Propionate for Chronic Hand Dermatitis
The purpose of the study is to assess the safety, efficacy and tolerability of Clobetasol propionate foam in subjects with chronic dermatitis.
- Trial name
- NCT00828464
- Testing
- clobetasol propionate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stiefel, a GSK Company
Contact Dermatitis, Eczema, Contact
Novel Topical Treatment of Hand Dermatitis (Eczema)
This study is designed as a prospective, randomized, double-blind right/left comparison of Epikeia coatings to improve hand dermatitis.
- Trial name
- NCT00614289
- Testing
- Epikeia Coatings
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Biomedical Development Corporation
Chronic Hand Eczema
Prospective Real-World Clinical Investigation on Dexyane Med® in Adults With Chronic Hand Eczema
Prospective, descriptive, multicenter, real-world, international clinical investigation. Data collection is based on current clinical practice over a 6-month follow-up period using both electronic Case Report Form (eCRF) and…
- Trial name
- CARING (NCT05545215)
- Testing
- Dexyane Med
- Sponsor
- Pierre Fabre Medicament
Chronic Hand Eczema
Open-label Multi-site Extension Trial in Subjects Who Completed the DELTA 1 or DELTA 2 Trials
The purpose of this extension trial is to evaluate the long-term safety of delgocitinib. Subjects will visit the clinic every 4 week to assess the safety and efficacy of the treatment, until Week 36.
- Trial name
- DELTA 3 (NCT04949841)
- Testing
- Delgocitinib
- Where
- 95 sites in Belgium, Canada and 8 more
- Volunteers
- 801 people
- Sponsor
- LEO Pharma
Palmar-Plantar Erythrodysesthesia Syndrome
Safety and Efficacy Placebo Controlled Study of ATH008 Cream in PPES Patients Secondary to Capecitabine
The aim of this study is to evaluate the safety and efficacy of ATH008 cream in patients with Palmar-Plantar Erythrodysesthesia Syndrome (PPES) secondary to capecitabine therapy.
- Trial name
- NCT01316406
- Testing
- ATH008
- Where
- 26 sites in Belgium, Germany and 2 more
- Volunteers
- 122 people
- Sponsor
- Advancell - Advanced In Vitro Cell Technologies, S.A.