Clinical trials: Dermatitis Hand
Hand Eczema
Topical Ruxolitinib Evaluation in Chronic Hand Eczema Study 1
The purpose of this study is to evaluate the efficacy and safety of ruxolitinib cream in adult participants with diagnosis of chronic hand eczema (CHE) and moderate to severe disease activity (Investigator's Global Assessement…
- Trial name
- TRuE-CHE1 (NCT05219864)
- Testing
- Ruxolitinib cream, Vehicle
- Where
- 49 sites in United States, Canada and 4 more
- Sponsor
- Incyte Corporation
Hand-Foot Syndrome, Breast Cancer
Ice Plant Intensive Cream for the Prevention of Hand-Foot Syndrome in Breast Cancer: Pilot Randomized Controlled Trial
The present pilot study investigates the feasibility of a prospective larger confirmatory study on the efficacy of Dr. Hauschka Med Ice Plant Intensive Cream for the prevention of hand-foot syndrome in patients with breast…
- Trial name
- WIn-HFS (NCT05755646)
- Testing
- Ice Plant Intensive Cream plus Standard Care, Standard Care
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- University Hospital Tuebingen
Chronic Hand Eczema
Efficacy and Safety of Delgocitinib Cream in Adults With Moderate to Severe Chronic Hand Eczema
This was a 16-week study in adult participants with chronic hand eczema (CHE). > The participants visited the clinic regularly to have the study doctor assess their CHE and to answer questions about itch, pain, CHE symptoms, and…
- Trial name
- DELTA 1 (NCT04871711)
- Testing
- Delgocitinib cream, Cream vehicle
- Where
- 54 sites in Canada, France and 4 more
- Volunteers
- 487 people
- Sponsor
- LEO Pharma
Dermatitis, Chronic
Ethanol-Free Clobetasol Propionate Foam 0.05% (Olux-E Foam) vs Vehicle Foam in the Treatment of Chronic Hand Dermatitis.
The purpose of this study is to determine how clobetasol proprionate foam works against a placebo foam in the treatment of hand dermatitis.
- Trial name
- NCT01323673
- Testing
- clobetasol propionate 0.05%
- Where
- 10 sites in United States
- Volunteers
- 125 people
- Sponsor
- Stiefel, a GSK Company
Ovarian Neoplasm
DOXIL for Consolidation Therapy in Ovarian Cancer.
The primary objective for this study is to evaluate the development, frequency and severity of hand foot syndrome (HFS) in ovarian cancer subjects treated with Doxil®, as consolidation therapy, on an every two week schedule.
- Trial name
- NCT00248248
- Testing
- liposomal doxorubicin
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Southeastern Gynecologic Oncology
Chronic Hand Eczema
PPDTM CorEvitasTM Chronic Hand Eczema (CHE) Drug Safety and Effectiveness Registry
The design is a prospective, observational registry for subjects with CHE under the care of dermatology or other qualified healthcare provider.
- Trial name
- NCT07598058
- Testing
- Observational (Non-Interventional) Registry
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- CorEvitas
Hand Eczema
A 24-week Single-blind Trial of Prevention of Hand Eczema in Cleaners
This study aims to investigate the effectiveness of picture-based prevention education among professional hospital cleaners in relation to hand eczema.
- Trial name
- HEIC (NCT05763914)
- Testing
- Change in the incidence of hand eczema, Change in severity of hand eczema, Change in the number of self-reported days with absence from work due to having hand eczema
- Where
- Denmark
- Volunteers
- 234 people
- Sponsor
- Zealand University Hospital
Chronic Hand Eczema
Treatment of Chronic Hand Eczema With Oral Roflumilast (HERO)
This study is a multicentre, double-blinded, randomized, placebo-controlled, clinical trial with open-label extension. The purpose and aim of this study is to investigate the efficacy and safety of roflumilast (PDE4-inhibitor) in…
- Trial name
- NCT05682859
- Testing
- Roflumilast 500 Mcg Oral Tablet
- Where
- Denmark
- Volunteers
- 41 people
- Sponsor
- Jacob Pontoppidan Thyssen
Eczema, Dermatitis
A Randomised Clinical Trial in a Population of Health Care Workers With Hand Eczema
Objectives and perspective: 1. To estimate the prevalence of hand eczema in a cohort of health care workers and assess exposures in the hospital environment that can lead to hand eczema .
- Conditions
- Eczema, Dermatitis, Skin Disease
- Trial name
- HET (NCT01012453)
- Testing
- A randomised clinical trial of the effect of classification and individual counselling
- Where
- 3 sites in Denmark
- Volunteers
- 300 people
- Sponsor
- Zealand University Hospital
Hand-foot Syndrome
The Effect of Topical Brimonidine Tartrate on Hand-foot Syndrome (HFS) in Cancer Patients
Comparative analysis of the severity of Hand-Foot-Syndrome (HFS) of palms treated with brimonidine tartrate gel or with standard care Urea 10% containing lotion in cancer patients receiving antineoplastic therapy to show a…
- Trial name
- BRIMOCAN (NCT03173365)
- Testing
- Brimonidine Tartrate
- Where
- Germany
- Volunteers
- 2 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Hand Dermatosis
Compatibility of a Mild, Moisturizing Hand Cleanser for Patients With Mild to Moderate Hand Dermatitis
The purpose of this study is to find out if the use of a hand cleanser that adds moisture to the skin will help improve skin rashes caused by frequent hand washing (hand dermatitis).
- Trial name
- NCT00843466
- Testing
- Mild, moisturizing hand cleanser
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Wake Forest University
Palmar-Plantar Erythrodysesthesia, Breast Cancer
Study of 0.1% Uracil Topical Cream (UTC) for the Prevention of Hand-Foot Syndrome
The purpose of this research study is to see if combining uracil cream (UTC) with capecitabine (Xeloda) can prevent Hand-Foot Syndrome.
- Trial name
- NCT01100463
- Testing
- Cream, 0.1% Uracil Cream
- Where
- 6 sites in United States
- Volunteers
- 18 people
- Sponsor
- Nanometics (d.b.a. PHD Biosciences)
Dermatitis, Nevus
Assessment of Digital Imaging as a Tool for Diagnosing Psoriasis, Hand Rashes and Unusual Moles
This study will evaluate whether digital photography is a reliable tool for diagnosing hand rashes, psoriasis and unusual moles.
- Conditions
- Dermatitis, Nevus, Psoriasis
- Trial name
- NCT00005781
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- National Cancer Institute (NCI)
Hand and Foot Syndrome, Erythrodysesthesia Syndrome
Possible Protective Effect of Celecoxib Against Capecitabine Induced Hand and Foot Syndrome in Patients With Colorectal Cancer
Colorectal cancer (CRC) is the third most common cancer and the second leading cause of malignancy-related mortality. Capecitabine has been approved for the treatment of colorectal cancer as first-line therapy.
- Conditions
- Hand and Foot Syndrome, Erythrodysesthesia Syndrome, HFS, Colorectal Cancer
- Trial name
- HFS (NCT05327751)
- Testing
- Celecoxib 200mg, Capecitabine-based chemotherapy
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Tanta University
Hand Eczema
Prevention of Hand Eczema Among Workers in the Fishing Industry in Greenland
This study aims to investigate the effect of a prevention programme on hand eczema among workers in the Greenlandic fishing industry.
- Trial name
- HEFIG (NCT06997393)
- Testing
- Prevention programme
- Where
- 4 sites in Greenland
- Volunteers
- 70 people
- Sponsor
- Bispebjerg Hospital
Atopic Dermatitis, Atopic Eczema
Comparison of Video-Based Versus Written Patient Education on Atopic Dermatitis
The purpose of this study is to compare the effect of video-based patient education with written instruction on subjects' knowledge of atopic dermatitis and their disease severity, measured by the Patient-oriented Eczema Measure…
- Conditions
- Atopic Dermatitis, Atopic Eczema, Infantile Eczema, Hand Eczema
- Trial name
- NCT00826592
- Testing
- Patient Educational Materials
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, Davis
Chronic Hand Eczema, Atopic Dermatitis
Characterization of Chronic Hand Eczema
Prospective longitudinal study to characterize Choronic Hand Eczema (CHE) subtypes and Atopic Dermatitis (AD) with noninvasive molecular and imaging techniques, and assess changes through time and its association with quality of…
- Trial name
- NCT05026554
- Testing
- Tape stripping
- Where
- Canada
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Dr. Robert Bissonnette
Hand Eczema
LEO19123 Cream in the Treatment of Hand Eczema
To compare the efficacy and safety of two different dose combinations of LEO19123 cream (calcipotriol and LEO80122) with LEO19123 cream vehicle for 3 weeks in the treatment of patients with hand eczema.
- Trial name
- NCT00404196
- Testing
- Calcipotriol and LEO80122 (LEO19123 cream)
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- LEO Pharma
Chronic Hand Eczema (CHE)
Topical Ruxolitinib Evaluation in Chronic Hand Eczema Study 2
The purpose of this study is to evaluate the efficacy and safety of ruxolitinib cream in adult participants with diagnosis of chronic hand eczema (CHE) and moderate to severe disease activity (Investigator's Global Assessement…
- Trial name
- TRuE-CHE2 (NCT05233410)
- Testing
- Ruxolitinib cream, Vehicle
- Where
- 39 sites in United States, Bulgaria and 5 more
- Sponsor
- Incyte Corporation
Dermatologic Complications, Palmar-plantar Erythrodysesthesia
Pyridoxine in Preventing Hand-Foot Syndrome Caused by Capecitabine in Patients With Cancer
RATIONALE: Pyridoxine may help prevent hand-foot syndrome caused by capecitabine in patients with cancer. It is not yet known whether pyridoxine is more effective than a placebo in preventing hand-foot syndrome in patients with…
- Conditions
- Dermatologic Complications, Palmar-plantar Erythrodysesthesia, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00486213
- Testing
- pyridoxine hydrochloride
- Where
- Singapore
- Volunteers
- 210 people
- Sponsor
- National Cancer Centre, Singapore