Clinical trials: Dermatologic Diseases
Melanoma (Skin)
Combination Chemotherapy With or Without Interleukin-2 and Interferon Alfa in Treating Patients With Metastatic Melanoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Interleukin-2 may stimulate a person's white blood cells to kill melanoma cells.
- Trial name
- NCT00003027
- Testing
- aldesleukin, filgrastim, recombinant interferon alfa
- Where
- 94 sites in United States
- Volunteers
- 482 people
- Sponsor
- Eastern Cooperative Oncology Group
Breast Cancer, Alpha Lipoic Acid
Effect of Alpha Lipoic Acid on Chemotherapy Induced Neurological Changes in Breast Cancer Patients
92 female cancer patients, aged from 18 to 75 years old (with a first diagnosis of breast cancer) who will receive Paclitaxel-based chemotherapy (12 weeks) as first line therapy, will be enrolled in the study and will be randomly…
- Conditions
- Breast Cancer, Alpha Lipoic Acid, Paclitaxel, Neurologic Disorder
- Trial name
- NCT06406127
- Testing
- Alpha Lipoic Acid 600 MG Oral Capsule
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Ain Shams University
n Ulcer, Scleroderma, Systemic
A Study to Evaluate the Efficacy of an Oral Medication in the Treatment and Prevention of Digital Ulcers in Patients With Systemic Sclerosis (Scleroderma).
This is a research study of an investigational drug called ambrisentan (Letairis) in the treatment and prevention of digital ulcers in patients with systemic sclerosis.
- Trial name
- NCT00725361
- Testing
- Ambrisentan
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stanford University
Psoriatic Arthritis
Clinical and Molecular Characterization of Axial Psoriatic Arthritis (PsA), A Pilot Study
Objectives: To identify a candidate set of biomarkers specific to AxPsA. Overview: Clinical and imaging characterization of PsA patients will be combined with extensive molecular assessment of both liquid and tissue compartments…
- Trial name
- MONOLITH (NCT05925842)
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Group for Research and Assessment of Psoriasis and Psoriatic Arthritis
Metastatic Melanoma
TNFα and IL-2 Coding Oncolytic Adenovirus TILT-123 With Lymphocyte-depleting Chemotherapy and TILs in the Treatment of Melanoma
This is an open-label, phase 1 trial evaluating the safety of oncolytic adenovirus TILT-123 in combination with lymphocyte-depleting chemotherapy and TILs in metastatic melanoma patients.
- Trial name
- TUNINTIL-2 (NCT06961786)
- Testing
- TILT-123, TIL, Cyclophosphamide
- Where
- Denmark
- Volunteers
- 9 people
- Sponsor
- TILT Biotherapeutics Ltd.
Androgenetic Alopecia, Male Pattern Baldness
A Study to Evaluate and Compare Injections of Autologous Dermal and Epidermal Cells Into the Balding Scalp of Subjects With Hair Loss (CA-0002013)
The purpose of the study is to evaluate the ability of injections Ji Gami(TM) to induce hair growth in male and female subjects with hair loss.
- Conditions
- Androgenetic Alopecia, Male Pattern Baldness, Female Pattern Baldness
- Trial name
- NCT01451073
- Testing
- Autologous cultured dermal and epidermal cells
- Where
- 6 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Aderans Research Institute
Onychomycosis
Isotretinoin Versus Excimer Light an Adjuvant in Treating Onychomycosis
3 groups of patients with onychomycosis will be recruited. Group A will receive itraconazole alone. Group B will receive itraconazole + low dose isotretinoin and group C will be treated with itraconazole + excimer light sessions.
- Trial name
- NCT06485505
- Testing
- ISOtretinoin 10 MG, excimer light, Itraconazole 200 mg
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Zagazig University
Erythropoietic Protoporphyria (EPP), X Linked Erythropoietic Protoporphyria
Effect of Isoniazid on Protoporphyrin Levels in Erythropoietic Protoporphyria
In erythropoietic protoporphyria there is an accumulation of protoporphyrin IX (PPIX) in the plasma and liver. The reason it builds up is either the last step to make heme, insertion of iron into PPIX, is rate limiting or there…
- Trial name
- INHEPP (NCT01550705)
- Testing
- Isoniazid
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Utah
ANCA Associated Vasculitis, Microscopic Polyangiitis
Hydroxychloroquine in ANCA Vasculitis Evaluation
The purpose of this study is to find out whether hydroxychloroquine, in addition to background treatments, reduces disease activity in patients with Anti-Neutrophilic Cytoplasmic Autoantibodies (ANCA) Vasculitis, a group of…
- Conditions
- ANCA Associated Vasculitis, Microscopic Polyangiitis, Churg-Strauss Syndrome, Wegener Granulomatosis
- Trial name
- HAVEN (NCT04316494)
- Testing
- Hydroxychloroquine
- Where
- 18 sites in United Kingdom
- Volunteers
- 43 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Cellulitis
The Effect of Dermatology and Teledermatology Consultations on Length of Hospital Admission, 30 Day Readmission Rate, and Antibiotic Use in Patients Presenting With Cellulitis vs Pseudocellulitis in an Academic Inpatient Setting
The effect of teledermatology on length of hospital admission, length of stay, 30 day readmission rate, and antibiotic use in patients presenting with cellulitis vs pseudocellulitis in an academic emergency department setting.
- Trial name
- NCT03034694
- Testing
- teledermatology consult, Routine Care
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Cancer, Breast Cancer
Psychoneurological Symptom Cluster in Oncology
A psychoneurological symptom cluster is increasingly documented in oncology. It is composed of cancer-related fatigue, sleep difficulties, pain, emotional distress, and cognitive difficulties.
- Conditions
- Cancer, Breast Cancer, Digestive Cancer
- Trial name
- NCT05867966
- Testing
- psychoeduc/self-care/self-hypnosis group
- Where
- Belgium
- Volunteers
- 500 people
- Sponsor
- University of Liege
Metastatic Melanoma, Skin Cancer
Anti-MART-1 F5 Cells Plus ALVAC MART-1 Vaccine to Treat Advanced Melanoma
Background: Melanoma antigen recognized by T-cells (MART)-1 is a protein present in melanoma cells. An experimental procedure developed for treating patients with melanoma uses the anti-MART-1 F5 gene and a type of virus to make…
- Trial name
- NCT00612222
- Testing
- autologous anti-MART-1 F5 T-cell receptor gene-engineered peripheral blood lymphocytes, ALVAC MART-1 Vaccine, aldesleukin
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- National Cancer Institute (NCI)
Breast Cancer, Colorectal Cancer
Nurse-led Proactive Telephone Follow-up With Patients After Completion of Primary Cancer Treatment
The goal of this randomized study is to test and evaluate nurse-led telephone follow-up intervention in patients primarily curatively treated for breast cancer, colorectal cancer, and prostate cancer.
- Conditions
- Breast Cancer, Colorectal Cancer, Prostate Cancer
- Trial name
- NCT06223022
- Testing
- Proactive nurse-led telephone follow-up
- Where
- Sweden
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Umeå University
Breast Cancer
Study on Bisphosphonates Targeting Triple-negative Breast Cancer
Triple-negative breast cancer has a poor prognosis and lacks effective adjuvant treatment. A number of preclinical and clinical trials have shown that bisphosphonates have direct or indirect anti-tumor activity, and early use of…
- Trial name
- NCT04045522
- Testing
- Zoledronic Acid
- Where
- 3 sites in China
- Volunteers
- 120 people
- Sponsor
- Shengjing Hospital
Breast Cancer
A Clinical Study of HRS-6209 Combined With Other Treatment Regimens in Patients With Breast Cancer
This is a study to evaluate the safety, tolerability, and pharmacokinetic characteristics of HRS-6209 combined with other treatment regimens in breast cancer patients, and preliminarily observe its anti-tumor efficacy.
- Trial name
- NCT06974929
- Testing
- HRS-6209 Capsules, Letrozole Tablets, HRS-2189 Tablets
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Chronic Urticaria
Stress Intervention for Chronic Urticaria
Stress and chronic urticaria has been linked. The purpose of the study is to evaluate a patients chronic urticaria and stress levels before and after he/she goes through six sessions designed to help that participant manage…
- Trial name
- NCT01111136
- Testing
- Stress intervention
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Mississippi Medical Center
Breast Cancer
Testing Conversation Aid in Practice
The goal of this research study is to develop and test a website to help primary care providers (PCPs) discuss the pros and cons of mammography with women aged 75 and older and to help participants make decisions about…
- Trial name
- NCT06011434
- Testing
- Mammography Screening Conversation Aid
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Pressure Ulcers, Prevention
Study on Pressure Ulcers Prevention With Mepilex® Border Sacrum Dressing in Scheduled Cardiovascular Surgery
The study is a randomised controlled trial of patients admitted for a scheduled cardiac surgery at the Clermont-Ferrand hospital.
- Conditions
- Pressure Ulcers, Prevention, Skin Ulcer, Ulcer
- Trial name
- MEPICARD (NCT03823963)
- Testing
- Mepilex® Border dressing, Standard care
- Where
- France
- Volunteers
- 478 people
- Sponsor
- University Hospital, Clermont-Ferrand
Seborrheic Dermatitis
Safety and Efficacy Study in Subjects With Seborrheic Dermatitis
The purpose of this study is to determine if two test products are safe and effective in the treatment of seborrheic dermatitis.
- Trial name
- NCT01703793
- Testing
- Test Product 49778, Test Product 10156
- Where
- 22 sites in United States
- Volunteers
- 240 people
- Sponsor
- Medicis Global Service Corporation
Breast Cancer, Metastatic Invasive Lobular Breast Cancer
Detection and Outcomes in Metastatic Invasive Lobular Breast Cancer Through Novel F-18 FAP PET
This study is a pilot clinical imaging trial of a prospective, head-to-head comparison of 18F-Fibroblast Activation Protein Inhibitor (FAPI)-74 PET/CT versus standard-of-care 18F-Fluorodeoxyglucose (FDG) PET/CT in 15 patients…
- Trial name
- NCT07285993
- Testing
- 18F-FAPI-74, 18F-FDG, PET/CT
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Randy Yeh
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.