Clinical trials: Dermatology
Chronic Plaque Psoriasis, Plaque Psoriasis
Comparative Study on Unani Formulation Vs Active Control in Plaque Psoriasis
This trial tests whether a Unani ointment (Marham-e-Asfedaj) plus an oral Unani formulation (Mundij wa Mushil-i Sawdā) works better than a active treatment (salicylic acid 3% solution, also combined with Mundij wa Mushil-i Sawdā)…
- Conditions
- Chronic Plaque Psoriasis, Plaque Psoriasis, Psoriasis, Taqashshur al Jild
- Trial name
- NCT07841314
- Testing
- Marham Asfedaj, Mundij wa Mushil Sawda (Unani Oral decoction), Coal tar 1% & Salicylic acid 3 % solution
- Where
- India
- Volunteers
- 54 people
- Sponsor
- National Institute of Unani Medicine, Bengaluru
Chronic Plaque-type Psoriasis
AIN457 Regimen Finding Study in Patients With Moderate to Severe Psoriasis
The purpose of the study is to determine whether, in patients with moderate to severe plaque-type psoriasis, AIN457 administered subcutaneously reduces the severity of psoriasis symptoms and the extent to which the patient's body…
- Trial name
- NCT00941031
- Testing
- AIN457, AIN457A
- Where
- 62 sites in United States, France and 5 more
- Volunteers
- 404 people
- Sponsor
- Novartis Pharmaceuticals
Dermatology/Skin - Other
Pilot Evaluation of Thulium Laser Alone or in Combination With Broad Band Light for Treatment of Dermatologic Conditions
Evaluate the Thulium laser device for skin resurfacing procedures, or as a treatment for pigmented lesions (age or sun spots) or dyschromia; or cutaneous lesions such as, but not limited to, actinic keratosis, melasma, fine…
- Trial name
- NCT03944278
- Testing
- Thulium Laser
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Sciton
Keloid
Case-control Study on Matrix Metalloproteinase Levels in Tissue in Patients With Keloid Scar
Purpose: To compare the levels of matrix metalloproteinase-1 (MMP-1), MMP-8, MMP-13 and tissue inhibitor of metalloproteinases (TIMPs) in keloid skin tissue with normal skin in the same patient and with normal discarded skin…
- Trial name
- NCT01125137
- Testing
- Removal of Keloid
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Head and Neck Squamous Cell Carcinoma, Colorectal Cancer
Satisfaction and Quality of Life Comparison Between Patients Using Cicaplast Baume B5 Versus Dexeryl for the Management of Cutaneous Toxicities Induced by Epidermal Growth Factor Receptor Inhibitors (iEGFR)
This randomized comparative study aims to evaluate the satisfaction and quality of life of patients using Cicaplast balm B5, versus Dexeryl, for the management of cutaneous toxicities of iEGFR in squamous cell carcinoma of the…
- Conditions
- Head and Neck Squamous Cell Carcinoma, Colorectal Cancer, Non Small Cell Lung Cancer, Epidermal Growth Factor Receptor Inhibitor
- Trial name
- CICAFIX (NCT03421912)
- Testing
- Cicaplast Balm B5, Dexeryl
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Centre Leon Berard
Lymph Node Cancer, Cutaneous
Epidemiology and Management of Cutaneous T-Cell Lymphoma at Hospital México, Costa Rica.
Adult patients (≥18 years) with confirmed cutaneous T-cell lymphoma evaluated at Hospital México between 2019 and 2025 will be retrospectively analyzed using EDUS records to describe their epidemiological profile, clinical…
- Conditions
- Lymph Node Cancer, Cutaneous, T-cell Lymphoma
- Trial name
- NCT07538960
- Where
- Costa Rica
- Volunteers
- 350 people
- Sponsor
- Caja Costarricense de Seguro Social
Dermatitis
Interest of Photographs by Smartphone in Dermatology
To study the diagnostic performance of the images on the smartphone compare the result of the clinical examination, all the dermatoses combined and by family of pathology (inflammatory, wound, oncology, infectious, allergology)…
- Trial name
- PHOTODERM (NCT03493724)
- Testing
- telemedecine
- Where
- France
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Local Anaesthetic Complication, Pain
Kinetic Anesthesia Device Study
Patients experience discomfort from lidocaine injections. Vibrating kinetic anesthesia devices (KAD) have been shown to reduce pain of injections in dentistry, pediatrics, and dermatology, though no studies of lidocaine…
- Trial name
- NCT03344510
- Testing
- Kinetic Anesthesia Device, Control
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Actinic Keratosis
Study to Determine the Safety of PEP005 0.025% and 0.05% Topical Gel in Patients With Actinic Keratoses
The purpose of this study is to determine whether topical application of PEP005 is safe for the treatment of actinic keratoses.
- Trial name
- NCT00375739
- Testing
- PEP005
- Where
- 24 sites in United States
- Volunteers
- 200 people
- Sponsor
- Peplin
Skin Aging
Efficacy and Safety of Skin Care Product in Aging Facial Skin
The purpose of this study is to assess the efficacy and safety of P29429-01 as a skin care product to manage skin aging in women subjects 40-65 years of age.
- Trial name
- NCT04015063
- Testing
- Anti-Aging Skin Care product
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Abdominal Pain/Gastrointestinal Issues, Lower Respiratory System Conditions
Clinic Waiting Room-based Study of Swahili Language Artificial Intelligence-driven Symptom Assessments in Tanzanian Primary Health Care Facilities
This study will evaluate the accuracy of the condition suggestions and urgency advice of the Swahili language Ada symptom assessment application (SAA), when symptoms are input by a lay-person user and a medical professional…
- Conditions
- Abdominal Pain/Gastrointestinal Issues, Lower Respiratory System Conditions, Upper Respiratory System Conditions, Mental Health Conditions
- Trial name
- AFYA (NCT04958577)
- Testing
- Ada Waiting Room App (WRA) and Ada Diagnostic Support Application (HDA)
- Where
- Tanzania
- Volunteers
- 109 people
- Sponsor
- Ada Health GmbH
Psoriasis (PsO), Obesity & Overweight
Effects of Semaglutide on Clinical Outcomes and Metabolic Inflammation in Psoriasis
This study will evaluate the effects of oral semaglutide in combination with topical corticosteroid/calcipotriol on clinical outcomes and metabolic inflammation in patients with plaque psoriasis and overweight/obesity and/or type…
- Conditions
- Psoriasis (PsO), Obesity & Overweight, Diabetes Mellitus - Type 2
- Trial name
- SEMAPSO (NCT07401992)
- Testing
- Semaglutide (Rybelsus®)
- Where
- Mexico
- Volunteers
- 62 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Dermatology, Female Pattern Baldness
Efficacy and Safety of Topical Vitamin D Analogue in Treatment of Female Pattern Hair Loss
The trial aims to study efficay of topical vitamin D analogue in treatment of female pattern hair loss cases
- Trial name
- NCT06333600
- Testing
- Topical minoxidil, Topical Vitamin D, Saline spray
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Sohag University
Dermatologic Disorders
Use of Alternative Medicine Among Outpatients in Dermatology and Primary Care Clinics
This study is to assess the practice of complementary and alternative medicine (CAM) for skin related conditions among patients in the Primary Care and Dermatology clinics.
- Trial name
- NCT01660139
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Psoriasis
Swiss Dermatology Network of Targeted Therapies (SDNTT)
The purpose of this study is to evaluate the long-term course of patients with psoriasis and psoriatic-arthritis in systemic treatments such as, methotrexate, cyclosporin A, fumaric acids, acitretin, systemic PUVA, etanercept…
- Trial name
- SDNTT (NCT01706692)
- Testing
- Adalimumab, Etanercept, Infliximab
- Where
- 6 sites in Switzerland
- Volunteers
- 1,121 people
- Sponsor
- Swiss Dermatology Network for Targeted Therapies
Basal Cell Carcinoma
High Intensity Focused Ultrasound (HIFU) Treatment of Basal Cell Carcinoma
The overall objective of the study is to evaluate the safety and efficacy of treatment of Basal Cell Carcinoma (BCC) using a new modality based on high-intensity focused ultrasound (HIFU).
- Trial name
- HIFU-BCC (NCT05698706)
- Testing
- TOOsonix System ONE-M
- Where
- Poland
- Volunteers
- 27 people
- Sponsor
- Jacek Calik
Xanthelasma Palpebrarum
Topical 2% Simvastatin for Xanthelasma Palpebrarum
This study is evaluating whether a topical cream containing 2% simvastatin can improve xanthelasma palpebrarum, a common condition that causes yellow cholesterol deposits on the eyelids.
- Trial name
- STAT-LID (NCT07662785)
- Testing
- Topical Simvastatin 2% Cream, Vehicle cream
- Volunteers
- 30 people
- Sponsor
- Klira Skin
Psoriasis, Atopic Dermatitis
Tailored Patient-Provider Communication (TPPC): Evaluating the Impact of TPPC in Dermatology Patients
The impact of tailored patient-provider communication to improve clinical trial recruitment, patient knowledge, and patient engagement will be studied.
- Conditions
- Psoriasis, Atopic Dermatitis, Acne
- Trial name
- NCT04633616
- Testing
- Tailored Patient-Provider Communication, Non-Tailored Patient-Provider Communication
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Psoriasis
Tunisian National Registry on Psoriasis
National cross-sectional multicentric study to describe the epidemiological characteristics of patients with Psoriasis in Tunisia
- Trial name
- PsoTReg (NCT05258838)
- Where
- Tunisia
- Volunteers
- 1,100 people
- Sponsor
- Dacima Consulting
Actinic Keratosis
A Study to Examine the Safety and Toleration of PEP005 Topical Gel in Patients With Actinic Keratoses on the Top of the Hand
The purpose of this study is to examine the safety and toleration of PEP005 Topical Gel, administered on an actinic keratosis (AK) treatment area on the top of a hand.
- Trial name
- NCT00544297
- Testing
- PEP005 gel
- Where
- 4 sites in United States
- Volunteers
- 12 people
- Sponsor
- Peplin