Clinical trials: Dermatology, active
Acne Vulgaris, Acne Vulgaris on the Face
Study of New Antiandrogenic Progestogen + Low-dose Estrogen for Moderate Acne Vulgaris
This Phase III randomized, double-blind, placebo-controlled, adaptive, multicenter study evaluates the efficacy and safety of a new concentration of the fixed-dose combination EF190 in women with moderate acne vulgaris over six…
- Trial name
- PANDORA (NCT06905210)
- Testing
- Experimental drug (Cyproterone Acetate 2 mg and Ethinyl Estradiol 0.02 mg)
- Where
- 18 sites in Brazil
- Volunteers
- 531 people
- Sponsor
- Eurofarma Laboratorios S.A.
Solitary Skin Lesions, Skin Neoplasms
CNN-Based AI Versus Physicians for Solitary Skin Lesion Diagnosis
The goal of this observational study is to evaluate the diagnostic accuracy of a CNN-based artificial intelligence model in patients with solitary skin lesions.
- Conditions
- Solitary Skin Lesions, Skin Neoplasms, Skin Neoplasm Malignant
- Trial name
- NCT07415291
- Where
- Turkey (Türkiye)
- Volunteers
- 17,625 people
- Sponsor
- Istanbul Training and Research Hospital
Palmoplantar Keratoderma
Study to Evaluate the Safety and Efficacy of Tapinarof in Adults With Palmoplantar Keratoderma
The purpose of this study is to assess adults with palmoplantar keratoderma (thickening skin layer on palms and soles) who are treated with the study drug, tapinarof.
- Trial name
- NCT06561321
- Testing
- Tapinarof
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Indiana University
Atopic Dermatitis
Clinical Study of Trilinolein Cream for Prevention of Relapse in Remission of Moderate-to-severe Atopic Dermatitis.
This multicenter, randomized, double-blind, placebo-controlled will be conducted at Yueyang Hospital of Integrative Medicine, Shanghai University of Traditional Chinese Medicine; Seventh People's Hospital, Shanghai University of…
- Trial name
- NCT06463353
- Testing
- trilinolein cream group, cream base group
- Volunteers
- 376 people
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Inflammatory Bowel Diseases, Ulcerative Colitis
Evolution and Treatments of Chronic Inflammatory Systemic Diseases
Patients with chronic inflammatory diseases (CID) followed in gastroenterology, dermatology and rheumatology have physiopathological, epidemiological and therapeutic focal points.
- Conditions
- Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease, Arthritis, Rheumatoid
- Trial name
- MISTIC (NCT04191395)
- Where
- France
- Volunteers
- 3,000 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Chronic Urticaria, Chronic Spontaneous Urticaria
Apremilast Added to Antihistamines in Chronic Urticaria
This study evaluates whether adding oral apremilast, a phosphodiesterase-4 inhibitor, to second-generation H1 antihistamines improves disease activity and quality of life in adults with chronic urticaria that is not controlled by…
- Conditions
- Chronic Urticaria, Chronic Spontaneous Urticaria, Chronic Inducible Urticaria
- Trial name
- APREM-CU (NCT07850843)
- Testing
- Apremilast, Second-generation H1 antihistamine
- Where
- Pakistan
- Volunteers
- 86 people
- Sponsor
- Rashid Latif Medical College
Dermatophyte Infection
Fungal Resistance in Dermatophyte Infection
The aim of the study is to compare the efficiency of broth microdilution versus disk diffusion method for antifungal drug susceptibility testing of the most used drugs in dermatophytosis treatment.
- Trial name
- NCT06729216
- Testing
- Antifungal susceptibility testing (AFST)
- Volunteers
- 42 people
- Sponsor
- Cairo University
Skin Conditions and Traditional Medicine
Public Attitudes Towards Traditional Medicine in Dermatological Care Within Blantyre, Malawi: Insights From Subject Matter Experts
This study aims to understand how people in Blantyre, Malawi recognise and manage common skin problems, and what role traditional medicine plays in their care.
- Trial name
- PATTMIDC (NCT07812844)
- Volunteers
- 13 people
- Sponsor
- University of Edinburgh
Skin Cancer Prevention, Melanoma In Situ
Early Detection of Skin Tumors Using a Telemedicine Tool in Primary Care
The project is a national, prospective, multicenter, single-arm interventional pilot of screening skin tumors in the Czech Republic.
- Conditions
- Skin Cancer Prevention, Melanoma In Situ, Skin Lesions, Skin Cancer
- Trial name
- MEL (NCT07349940)
- Testing
- Intervention with telemedicine tool
- Where
- 5 sites in Czechia
- Volunteers
- 1,440 people
- Sponsor
- Institute of Health Information and Statistics of the Czech Republic
Cradle Cap, Seborrheic Dermatitis
TRIDERM D.S. Crema Normalizzante for Neonatal Hyperseborrhea (Cradle Cap) and Associated Cutaneous Manifestations of Mild-to-Moderate Seborrheic Dermatitis in Children Aged 0 to 3 Years
This clinical study aims to evaluate the effects of using the cosmetic product TRIDERM D.S. Crema Normalizzante in children aged 0 to 3 years with neonatal hyperseborrhea ("cradle cap"), potentially associated with manifestations…
- Trial name
- NCT07860788
- Testing
- TRIDERM D.S. Crema Normalizzante
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- ICIM International S.r.l.
Chronic Plaque Psoriasis, Plaque Psoriasis
Comparative Study on Unani Formulation Vs Active Control in Plaque Psoriasis
This trial tests whether a Unani ointment (Marham-e-Asfedaj) plus an oral Unani formulation (Mundij wa Mushil-i Sawdā) works better than a active treatment (salicylic acid 3% solution, also combined with Mundij wa Mushil-i Sawdā)…
- Conditions
- Chronic Plaque Psoriasis, Plaque Psoriasis, Psoriasis, Taqashshur al Jild
- Trial name
- NCT07841314
- Testing
- Marham Asfedaj, Mundij wa Mushil Sawda (Unani Oral decoction), Coal tar 1% & Salicylic acid 3 % solution
- Where
- India
- Volunteers
- 54 people
- Sponsor
- National Institute of Unani Medicine, Bengaluru
Aesthetic Procedures, Cosmetic Techniques
MENA Consensus on Poly-L-Lactic Acid (PLLA) Biostimulator Use in Aesthetic Dermatology
This study aims to develop expert consensus on the safe and effective use of poly-L-lactic acid (PLLA) biostimulators in aesthetic dermatology across the Middle East and North Africa (MENA) region.
- Conditions
- Aesthetic Procedures, Cosmetic Techniques, Skin Aging, Rejuvenation
- Trial name
- NCT07261748
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Venus Research Center
Eczema, Atopic Dermatitis
Cutaneous Biomarkers in Atopic Eczema Using a Non-Invasive Micro-Suction Device in Babies
This project aims to establish whether an adapted extraction device is tolerable and will be able to measure chemical signals in baby's ISF.
- Conditions
- Eczema, Atopic Dermatitis, Atopic Eczema
- Trial name
- CARE (NCT07228962)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King's College London
Melanoma
Spanish Academy of Dermatology and Venereology (AEDV) Melanoma Registry
The goal of this patient registry is to describe risk factors for bad prognosis of melanoma in Spain. The main questions it aims to answer are: To describe socioeconomical individual risk factors associated with melanoma…
- Trial name
- NCT05673681
- Where
- 21 sites in Spain
- Volunteers
- 7,000 people
- Sponsor
- Fundación Academia Española de Dermatología
Skin Melanoma, Cutaneous Melanoma
Melanoma of the Skin and Exposure to Solar Ultraviolet Radiation at Work in Modena Territory: a Case-control Study to Promote an Active Search and Prevention of Occupational Diseases Based on Recent INAIL Criteria
The goal of this observational study is to learn about the link between work-related sun exposure and a specific type of skin cancer called melanoma in people living in the Modena area, Italy.
- Trial name
- Mesur (NCT07251335)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Modena and Reggio Emilia
Atopic Dermatitis
Evaluation of a Non-Invasive Device for Early Detection of Atopic Dermatitis Flares
This study will collect skin measurements from people with atopic dermatitis (AD) using the investigational Nevisense Go device.
- Trial name
- Detect-AD (NCT07645820)
- Testing
- Nevisense electrical impedance spectroscopy
- Where
- 13 sites in United States
- Volunteers
- 450 people
- Sponsor
- Castle Biosciences Incorporated
Psoriasis
Assessment of the Effect of a Dermatology-Oriented Spa Therapy on the Quality of Life of Patients With Psoriasis
Evaluation of the effect of a dermatology-oriented spa therapy at 4.5 months on the quality of life of patients suffering from psoriasis
- Trial name
- BAREGES (NCT06735911)
- Testing
- Spa therapy
- Where
- 2 sites in France
- Volunteers
- 70 people
- Sponsor
- Thermes de Bareges
Chronic Dermatological Conditions, Eczema
A Randomised Controlled Trial of ePROM-Guided Flexible Scheduling in Dermatology
The goal of this clinical trial is to evaluate whether an electronic patient-reported outcome measure (ePROM)-guided flexible scheduling system can improve outpatient clinic resource utilisation in patients attending dermatology…
- Conditions
- Chronic Dermatological Conditions, Eczema, Urticaria, Psoriasis
- Trial name
- NCT07481019
- Testing
- Flexible ePROM-guided Scheduling System, electronic patient reported outcome measures (ePROMs)
- Volunteers
- 250 people
- Sponsor
- National University Hospital, Singapore
Radiofrequency Microneedling
Complications Associated With Radiofrequency Microneedling in Dermatology: a Delphi Consensus
Radiofrequency microneedling (RFMN) combines controlled delivery of radiofrequency energy into the dermis or subcutaneous tissue through arrays of insulated or non-insulated microneedles.
- Trial name
- NCT07443384
- Testing
- Delphi consensus on radiofrequency microneedling treatment for skin laxity
- Volunteers
- 30 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Acne Vulgaris
Low-Dose Versus Conventional-Dose Oral Isotretinoin for Acne Vulgaris
Background and Purpose: Acne vulgaris is a common skin condition that can cause significant physical and emotional distress. Oral isotretinoin is a highly effective treatment for severe or persistent acne.
- Trial name
- NCT07639073
- Testing
- Isotretinoin
- Where
- Pakistan
- Volunteers
- 164 people
- Sponsor
- Pakistan Institute of Medical Sciences