Clinical trials: Desflurane
Endoscopic Sinus Surgery
SPI-guided Analgesia During FESS for Intraoperative Blood Loss
The aim of this randomized trial is to assess the utility of Surgical Pleth Index (SPI) for monitoring pain perception intraoperatively and its influence on intraoperative blood loss, quality of surgical field using Boezaart…
- Trial name
- FESSSPI (NCT03417180)
- Testing
- Remifentanil, surgical pleth index
- Where
- 2 sites in Poland
- Volunteers
- 120 people
- Sponsor
- Medical University of Silesia
Transplant; Failure, Kidney
Effects of Sevoflurane and Desflurane on Treg
This prospective interventional study aims to compare sevoflurane and desflurane anesthetic agents on regulatory T cell (Treg) numbers and its cytokine production in patients undergoing Living Donor Kidney Transplant (LDKT).
- Trial name
- NCT02559297
- Testing
- Sevoflurane, Desflurane
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Postoperative Cognitive Dysfunction (POCD), Controlled Hypotension for Nasal Surgeries
Comparison of Desflurane, Sevoflurane, and Total Intravenous Anesthesia in Ear Surgery Under Controlled Hypotension
This randomized prospective study aimed to compare desflurane, sevoflurane, and total intravenous anesthesia methods in patients undergoing elective ear surgery under controlled hypotension, with a particular focus on…
- Trial name
- POCD-ENT (NCT07792759)
- Testing
- Desflurane, Sevoflurane, Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Pediatric Acute Respiratory Distress Syndrome, Desflurane
Effect of Desflurane on Pediatric Acute Respiratory Distress Syndrome After Living Donor Liver Transplant Recipients
Biliary atresia is a serious congenital anomaly characterized by persistent and progressive cholestatic jaundice. The incidence of biliary atresia is more common in East Asia, especially China, with an incidence of 2 per 10,000…
- Conditions
- Pediatric Acute Respiratory Distress Syndrome, Desflurane, Biliary Atresia
- Trial name
- EDPARDSLDLTR (NCT05783518)
- Testing
- desflurane, propofol
- Where
- 2 sites in China
- Volunteers
- 165 people
- Sponsor
- Tianjin First Central Hospital
Microcirculation, Anesthetic Complication Spinal
Effect of Anesthetics on Microcirculation in Patients Undergoing Off-pump Coronary Artery Bypass Surgery
Volatile anesthetics, such as sevoflurane and desflurane, are commonly used in patients undergoing cardiac surgeries including off-pump coronary artery bypass.
- Trial name
- NCT03209193
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Seoul National University Hospital
PD - Parkinson's Disease, Dexmedetomidine
Choice of Anesthesia in Microelectrode Recording Guided Deep Brain Stimulation for Parkinson's Disease
Subthalamic nucleus (STN)-deep brain stimulation (DBS) under general anesthesia has been applied to PD patients who cannot tolerate awake surgery, but general anesthesia will affect the electrical signal in microelectrode…
- Conditions
- PD - Parkinson's Disease, Dexmedetomidine, Desflurane, Deep Brain Stimulation
- Trial name
- CHAMPION (NCT05550714)
- Testing
- general anesthesia, Conscious sedation
- Where
- China
- Volunteers
- 188 people
- Sponsor
- Beijing Tiantan Hospital
Anesthesia
Power Spectral Analysis of EEG During Equi-MAC Inhalation Anesthesia
The purpose of this clinical trial is to compare hypnotic effect of sevoflurane and desflurane at equal minimum alveolar concentrations using power spectral analysis of the electroencephalogram.
- Trial name
- NCT02872389
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Kangbuk Samsung Hospital
Total Intravenous Anesthesia, Desflurane
TIVA Versus Desfluran Anaesthesia in Patients Undergoing Bariatric Surgery
Many factors during laparascopic surgery leads to PONV (postoperative nausea and vomiting), such as C02 insufflations causing peritoneal stretch and irritation and type of anaesthesia given during surgery.
- Conditions
- Total Intravenous Anesthesia, Desflurane, Obesity, Pain, Postoperative
- Trial name
- NCT03727607
- Testing
- Desflurane
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust
Cholelithiases, Appendicitis
Effect of Intravenous Lignocaine Infusion on Intraoperative End Tidal Desflurane Concentration Requirements
Lignocaine is a local anaesthetic that is widely used in all medical and surgical fields. Many clinical studies have shown that intravenous (IV) lignocaine given in the perioperative period was safe, reduced airway complications…
- Conditions
- Cholelithiases, Appendicitis, Ovarian Cysts
- Trial name
- NCT06064331
- Testing
- Lignocaine
- Where
- Malaysia
- Volunteers
- 48 people
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Desflurane Anesthesia, Postoperative Recovery
The Quality of Recovery From General Anesthesia With Desflurane for Fundus Surgery
The goal of this clinical trials to study and compare the effects of "desflurane with remifentanil anesthesia (study group)" and "sevoflurane with remifentanil anesthesia (control group)" for elective fundus surgery anesthesia.
- Trial name
- NCT06241131
- Testing
- Desflurane Inhalant Product
- Volunteers
- 220 people
- Sponsor
- Sichuan Provincial People's Hospital
Robotic-assisted Laparoscopic Radical Prostatectomy
The Comparison of Changes of QTc, Tp-e Interval, and Tp-e/QT Ratio, Tp-e/QTc Ratio on the ECG During Robotic-assisted Laparoscopic Radical Prostatectomy Under Sevoflurane, Desflurane and Total Intravenous Anesthesia -Randomized Controlled Trial
The purpose of this study is to compare the changes of QTc, Tp-e interval, and Tp-e/QT ratio, Tp-e/QTc ratio on the ECG during robotic-assisted laparoscopic radical prostatectomy under sevoflurane, desflurane and total…
- Trial name
- NCT03539003
- Testing
- sevoflurane, desflurane, propofol and remifentanil
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Yonsei University
Agitation
Effects of Serotonin Inhibitors on Patient-controlled Analgesia Related Nausea and Vomiting
ED50 of dexmedetomidine for prevention of emergence agitation after tonsillectomy or adenoidectomy in children
- Trial name
- NCT01517438
- Testing
- agitation
- Volunteers
- 21 people
- Sponsor
- Seoul National University Hospital
Desflurane Levels
A Pilot Study to Measure Blood Levels of Desflurane in Children
In this feasibility study we will collect blood from indwelling arterial catheters in up to 20 patients undergoing non-emergent surgery with desflurane anesthesia at Children's Hospital of Philadelphia.
- Trial name
- NCT00577369
- Testing
- Desflurane Levels
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Children's Hospital of Philadelphia
Anesthesia
Comparison of Effect of Equi-MAC Anesthetics on PSI
The aim of this study is to compare the patient state index values produced by equi-MAC of sevoflurane and desflurane in patients undergoing single-agent volatile anesthesia.
- Trial name
- NCT03587779
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 74 people
- Sponsor
- Kangbuk Samsung Hospital
Renal Failure
Desflurane vs. Sevoflurane in Endovascular Aortic Repair
Randomized Clinical Trial following the evaluation of the impact on renal function in patients undergoing endovascular aortic aneurysm repair with two anesthetics protocols (Desflurane versus Sevoflurane) on the first 24 hours…
- Trial name
- NCT03917186
- Testing
- Sevoflurane, Desflurane
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Begoña Quintana Villamandos
Coronary Artery Bypass, Delirium
Organ Protection for Coronary Artery Bypass Graft (CABG): Propofol Versus Desflurane
Background: Different anaesthetic agents have been shown to have different protective effects upon heart, brain and renal function under ischaemic conditions (oxygen starvation).
- Conditions
- Coronary Artery Bypass, Delirium, Dementia, Amnesia
- Trial name
- NCT00400790
- Testing
- propofol, desflurane
- Where
- Australia
- Volunteers
- 182 people
- Sponsor
- University of Melbourne
Aortocoronary Bypass, Cardiac Surgery
Volatile Anesthetics to Reduce Mortality in Cardiac Surgery
There is initial evidence that the choice of anesthesia can influence survival in the specific setting of coronary artery bypass grafting surgery (CABG).
- Conditions
- Aortocoronary Bypass, Cardiac Surgery, Coronary Artery Bypass Grafting
- Trial name
- MYRIAD (NCT02105610)
- Testing
- desflurane, isoflurane, sevoflurane, total intravenous anesthetics
- Where
- 36 sites in Bahrain, Brazil and 11 more
- Volunteers
- 5,400 people
- Sponsor
- Università Vita-Salute San Raffaele