Clinical trials: Detection
Ovarian Cancer
Safety in Ovarian Cancer for Average-Risk Women - Analysis
This study is designed to evaluate the safety, specificity, and downstream diagnostic burden of the Evident™ Ovarian Cancer Screening Test in average-risk postmenopausal women.
- Trial name
- SOARA (NCT07872644)
- Testing
- Blood-Based Ovarian Cancer Screening Test
- Where
- 2 sites in United States
- Volunteers
- 1,750 people, healthy volunteers welcome
- Sponsor
- Mercy BioAnalytics, Inc.
Coronary Artery Disease
Evaluation of the CardioSond Electronic Stethoscope in the Detection of Coronary Artery Disease
The study is designed to evaluate the predictive accuracy of the CardioSond digital electronic stethoscope in the detection of coronary artery disease (CAD) in patients with and without known disease who are referred to cardiac…
- Trial name
- NCT01374555
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- SonoMedica, Inc.
Thyroid Cancer, Thyroid Nodules
ctDNA in Patients With Thyroid Nodules
When the DNA inside of human cells undergoes certain alterations (mutations), the cells may develop into a cancer. The cancer cells may shed this DNA into the blood stream.
- Conditions
- Thyroid Cancer, Thyroid Nodules, Thyroid Adenoma, Thyroiditis
- Trial name
- NCT02778412
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Pathway Genomics
Colorectal Cancer Screening, Advanced Adenomas (AA)
Validation of a Molecular Signature for Early Detection of Colorectal Cancer
The goal of this Multicentre and international prospective study is to validate a molecular signature using plasma samples in average-risk population for colorectal cancer who undergo colonoscopy in a screening setting.
- Trial name
- NCT06738511
- Testing
- blood sampling, stool sampling, colonoscopy
- Where
- 2 sites in Germany, Poland
- Volunteers
- 3,421 people, healthy volunteers welcome
- Sponsor
- ADVANCED MARKER DISCOVERY S.L.
Chlamydial Infection, Gonococcal Infection
Clinical Evaluation of the Click Sexual Health Test for the Detection of Neisseria Gonorrhoeae (NG), Trichomonas Vaginalis (TV), and Chlamydia Trachomatis (CT) in Women
This study is a multi-center study with a minimum of three CLIA-waived intended operator sites in the United States in which prospectively self-collected vaginal specimens obtained from subjects who are symptomatic or…
- Conditions
- Chlamydial Infection, Gonococcal Infection, Trichomoniasis
- Trial name
- NCT04098900
- Testing
- Click Sexual Health Test
- Where
- 5 sites in United States
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- Visby Medical
Bladder Cancer
Study to Improve Detection and Early Recurrence Rate in Bladder Cancer Patients Using Hexvix Fluorescence Cystoscopy
The purpose of this study is to document the additional detection of papillary bladder cancer and the reduced early recurrence due to the improved detection and resection of these tumors after Hexvix cystoscopy compared to…
- Trial name
- NCT00233402
- Testing
- Hexvix, Standard white light cystoscopy
- Where
- 25 sites in United States, Austria and 3 more
- Volunteers
- 789 people
- Sponsor
- Photocure
Colon Polyp
Collecting Recorded Videos of Colonoscopy and Gastroscopy Tests for the Evaluation of the (ME-APDS).
The study shall mainly help to better evaluate the performance the ME-APDS device and secondly it may help the development of additional future versions of the ME-APDS.
- Trial name
- NCT06566872
- Testing
- ME-APDS
- Where
- Israel
- Volunteers
- 700 people
- Sponsor
- Magentiq Eye LTD
Post-operative Ileus
G-Tech Feasibility Study for Early Detection of a Post-op Ileus
This feasibility study is for the purpose of determining if the G-Tech Device can differentiate between normal return of GI activity post-operatively and the myoelectric activity in patients who develop a POI.
- Trial name
- GTECHPOI (NCT02673671)
- Testing
- G-Tech Myoelectric recording device
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- G-Tech Corporation
Stroke, Acute Stroke
Feasibility Assessment of the Wellumio 'Axana' 0.1T Portable MRI Device
To assess the safety and feasibility of the Wellumio 'Axana' device in the hospital setting with healthy controls and patients.
- Conditions
- Stroke, Acute Stroke, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- NCT07751328
- Testing
- Axana Scan and MRI
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wellumio R&D Australia Pty Ltd
Colon Cancer, Colon Adenomas
Plasma ctDNA in Patients Undergoing Diagnostic Colonoscopy
When the DNA inside of human cells undergoes certain alterations (mutations), the cells may develop into a cancer. The cancer cells may shed this DNA into the blood stream.
- Conditions
- Colon Cancer, Colon Adenomas, Colon Polyps
- Trial name
- NCT02665299
- Where
- United States
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Pathway Genomics
Colorectal Cancer, Polyp of Colon
EAGLE Trial CADDIE Artificial Intelligence Endoscopy
The EAGLE study is a prospective randomized controlled multicenter parallel design trial, for the assessment of clinical performance of the CADDIE device and to confirm that the device performs as expected.
- Conditions
- Colorectal Cancer, Polyp of Colon, Adenoma Colon
- Trial name
- EAGLE (NCT05730192)
- Testing
- Colonoscopy with CADDIE, Standard Colonoscopy
- Where
- 8 sites in Germany, Italy and 2 more
- Volunteers
- 985 people
- Sponsor
- Odin Medical
Mild Cognitive Impairment, Alzheimer Disease
Alzheimer's and Blood Glucose Levels
The Alzheimer's and Blood Glucose Levels Study is researching the differences in blood glucose levels between people with and without Mild Cognitive Impairment or Alzheimer's disease with the aim of early detection of Alzheimer's…
- Trial name
- NCT04614376
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bio Conscious Technologies Inc.
Coronary Artery Disease
Detection of Coronary Artery Disease With Micro Electro-Mechanical Sensors
This study aims to validate the sensor data of gyroscope and accelerometer in detection of hemodynamically significant CAD.
- Trial name
- DECADE (NCT04290091)
- Where
- Finland
- Volunteers
- 930 people
- Sponsor
- Precordior Ltd
Skin Carotenoids
Assessment of the Effects of a Daily Supplement 4Life Transfer Factor Vista Containing AREDS2 Formula on Skin Carotenoid Levels Using a Non-invasive Detection
The goal of the clinical study is to evaluate the impact of daily use of a dietary supplement TF Vista containing AREDS2 formula ingredients, astaxanthin (Haematococcus pluvialis) microalgae, bilberry (Vaccinium myrtillus) fruit…
- Trial name
- NCT07513597
- Testing
- Dietary Supplement
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- 4Life Research, LLC
Healthy Nutrition
Detection of Minor Changes in Fluid Volume or Tonicity in Healthy Volunteers.
This study is aimed at detecting minor changes in hydration volume and tonicity. We will use healthy students of both sexes who will ingest fluids and nutrition that should lead to specific changes in both intracellular and…
- Trial name
- CTR025 (NCT04937491)
- Testing
- New medical device (ReBalans)
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mode Sensors AS
Breast Cancer, Benign Breast Condition
ATUSA Ultrasound Diagnostic Imaging for Breast Lesions Evaluation (AUDIBLE) - iSono Health
AUDIBLE is a multi-site, clinical study conducted in the United States aimed at gathering data on 3D Automated Breast Ultrasound imaging using the iSono Health ATUSA system.
- Conditions
- Breast Cancer, Benign Breast Condition, Breast Fibroadenoma, Breast Neoplasms
- Trial name
- AUDIBLE (NCT07505797)
- Testing
- ATUSA 3D Automated Breast Ultrasound System
- Where
- 2 sites in United States
- Volunteers
- 800 people
- Sponsor
- iSono Health, Inc.
Migraine
Evaluation of Use of Brain Activity Monitoring for Prediction of Migraine Attacks
This study evaluates the use of brain activity monitoring for prediction of migraine attacks in an expected time scale of 12-48 hours prior to the migraine attack.
- Trial name
- NCT02583581
- Testing
- EEG monitoring (MindWave by NeuroSky), EEG monitoring (EPOC by Emotiv)
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Brainmarc Ltd.
Non Small Cell Lung Cancer
LIQUIK: LIQUId Biopsy for Detection of Actionable Genomic BiomarKers in Patients With Advanced Non-small Cell Lung Cancer (NSCLC)
To explore the non-inferiority of a cfDNA amplicon-based liquid biopsy technology vs. standard of care tissue biopsy-based NGS in detecting guideline- recommended biomarkers in patients with metastatic non-squamous Non-small Cell…
- Trial name
- LIQUIK (NCT04703153)
- Where
- 5 sites in United States
- Volunteers
- 151 people
- Sponsor
- Lucence Health Inc.
Breast Cancer
Pilot Mammography Reader Study to Assess Breast Cancer Detection in FFDM Plus DBT Versus FFDM Alone
The purpose of this pilot is to provide credible performance estimate information in order to conduct subsequent reader studies.
- Trial name
- NCT02511730
- Testing
- FFDM Plus DBT, FFDM
- Where
- 4 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fujifilm Medical Systems USA, Inc.
Urothelial Carcinoma
Detection and Risk Stratification in Veterans Presenting With Microscopic Hematuria
It is currently debated whether the use of invasive standard of care procedures, such as cystoscopy, a procedure which involves inserting a thin camera, called a cystoscope, into the bladder to look for signs of disease, is…
- Trial name
- microDRIVE (NCT05889195)
- Testing
- Cxbladder urine test
- Where
- 3 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Pacific Edge Limited