Clinical trials: Detection
Colorectal Cancer
Increasing Colorectal Cancer Screening in Urban African American Communities Via Churches
This is an intervention study to increase colorectal cancer screening and physical activity in members of African-American churches who are 50 years old and older.
- Trial name
- ACTS (NCT01139242)
- Testing
- Body & Soul nutritional intervention, Experimental: newsletters and peer counseling
- Volunteers
- 955 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Coronary Artery Disease
ST Segment Detection Study
The purpose of ST Detect study is to evaluate whether naturally occurring spontaneous coronary events and exercise induced cardiac ischemia, give rise to detectable changes on intracardiac electrogram (EGM) signals in patients…
- Trial name
- ST Detect (NCT00930969)
- Testing
- ICD
- Where
- 25 sites in United States, Austria and 5 more
- Volunteers
- 175 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Mouth Neoplasms
Oral Cancer Screening for Early Detection of Premalignant Disorders (PMOD)
Cancer is a complex disease; its different causes and types have a strong impact on patient treatment and prognosis. To improve understanding of the disease, its causes and progression, the investigators will develop a simple…
- Trial name
- PMOD (NCT05296941)
- Testing
- Brush sampling
- Where
- Sweden
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dalarna County Council, Sweden
CHD - Congenital Heart Disease, Single Ventricle Heart Disease
PRecision Integrated Saturation Monitor
The purpose of this study is to find out if an abdominal pulse oximeter device is as accurate as a conventional fingertip pulse oximeter in pediatric patients.
- Trial name
- PRISM (NCT07686341)
- Testing
- vital sign monitoring
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Le Bonheur Children's Hospital
Tuberculosis, Diagnoses Disease
TB-CAPT CORE Truenat Trial
A cluster randomized controlled trial to evaluate the effect of placing Truenat platform/TB assays at primary health care clinics combined with rapid communication of results on time to treatment initiation of microbiologically…
- Trial name
- NCT04568954
- Testing
- Truenat TB platform/TB assays
- Where
- 4 sites in Mozambique, Tanzania
- Volunteers
- 3,987 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Cholestasis in Newborn, Biliary Atresia
The Dirty Nappy Study
This observational study evaluates whether a machine-learning algorithm, a computer program that learns patterns from data, can accurately diagnose cholestasis in newborns.
- Conditions
- Cholestasis in Newborn, Biliary Atresia, Neonatal Cholestasis
- Trial name
- NCT07697872
- Where
- United Kingdom
- Volunteers
- 5,350 people, healthy volunteers welcome
- Sponsor
- Birmingham Women's and Children's NHS Foundation Trust
Traumatic Brain Injury, Cerebral Hemorrhage
TCD Detection of Ophthalmic Artery Blood Flow Velocity Prediction Feasibility Study of Intracranial Pressure
Increased intracranial pressure is a cause of disease progression in patients with brain disease, a common cause of poor prognosis.
- Conditions
- Traumatic Brain Injury, Cerebral Hemorrhage, Increased Intracranial Pressure
- Trial name
- NCT02240394
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Rheumatic Heart Disease
Artificial Intelligence to Scale Early Rheumatic Heart Disease Detection
The main goal of this project is to see if RADAR (Rapid AI-assisted Detection and Analysis of Rheumatic heart disease), which is a machine and deep-learning AI model, can help make rheumatic heart disease (RHD) screening easier…
- Trial name
- SHIELD 1 (NCT07599956)
- Testing
- AI assisted echocardiography
- Where
- Uganda
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
COVID-19
CoronaWatch - Early Detection of Cardiovascular Risks in COVID-19 Via SmartWatch
In December 2019, a new viral disease called COVID-19 emerged. It is caused by the new corona virus SARS-CoV-2. It was initially described in the chinese city of Wuhan.
- Trial name
- CoronaWatch (NCT04376853)
- Testing
- Apple Watch Series 5
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University Hospital Heidelberg
Type 1 Diabetes Mellitus
Detection of Vascular Injury in Diabetes Through Eye and Nailfold Data (DIVIDEND) - A Pilot Study
This project aimed to explore novel methods of detecting small blood vessel disease in a paediatric population with type 1 diabetes mellitus.
- Trial name
- DIVIDEND (NCT01279928)
- Testing
- Video Nailfold Capillaroscopy, Ambulatory 24 hr Blood Pressure Monitoring, Fundoscopy of eyes
- Where
- Australia
- Volunteers
- 26 people
- Sponsor
- John Hunter Hospital
Bladder Cancer
Detection of Bladder Tumors After 30 Min Instillation of Hexvix
The objective of the study is to compare Hexvix® flexible cystoscopy and white light flexible cystoscopy in the detection of histological confirmed bladder tumor lesions defined as dysplasia; CIS; Ta; T1; and ≥ T2 after 30…
- Trial name
- NCT01551407
- Testing
- Hexvix
- Where
- Germany
- Volunteers
- 38 people
- Sponsor
- Photocure
HELICOBACTER PYLORI INFECTIONS
Feasibility and Performance of FFPE qPCR for Detection of Clarithromycin Resistance in Helicobacter Pylori
This prospective observational study aims to evaluate the feasibility and performance of real-time PCR (qPCR) performed on formalin-fixed, paraffin-embedded (FFPE) gastric biopsies to detect Helicobacter pylori infection and…
- Trial name
- HED-2T (NCT07821294)
- Testing
- q-PCR on FFPE gastric biopsies
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Clinique Bizet
COPD, Asthma
AirSonea Wheeze Detection Study
The purpose of this study is to determine if the AirSonea device provides an objective assessment of breath sounds for the presence of wheeze in both medical and home environments.
- Trial name
- NCT01927172
- Testing
- AirSonea
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- iSonea
HER2-positive Gastric Cancer
ctDNA Screening in Advanced HER2 Positive Gastric Cancer
To identify molecular biomarker panel correlating with efficacy of trastuzuamb in advanced HER2 positive gastric cancer patients.
- Trial name
- NCT04520295
- Testing
- ctDNA screening
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Ruijin Hospital
Cervical Cancer
Non-invasive Biomarker Discovery for Pre-cervical or/and Cervical Cancer-HPV DNA and Other Biomarkers in Urine
The goal of this clinical trial is 1. To test the sensitivity and specificity of using HPV DNA from urine for the detection of pre-cervical or/and cervical cancer. 2.
- Trial name
- NCT06261892
- Testing
- Collect HPV DNA from urine
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- WomenX Biotech Limited
Colorectal Dysplasia, Colorectal Neoplasms
CAD EYE Detection of Remaining Lesions After EMR
In the last decade, many innovative systems have been developed to support and improve the diagnosis accuracy during endoscopic studies.
- Trial name
- NCT05542030
- Testing
- EMR with CAD-Eye™, EMR without CAD-Eye™, Follow-up colonoscopy with CAD-Eye™
- Where
- Ecuador
- Volunteers
- 60 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Breast Carcinoma
Mammography, Early Detection Biomarkers, Risk Assessment, and Imaging Technologies, MERIT Study
This study collects mammogram images, blood samples, and clinical information from women undergoing routine screening mammograms.
- Trial name
- NCT03408353
- Testing
- Biospecimen Collection, Mammography, Questionnaire Administration
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Colorectal Polyp
The Accuracy of Human Endoscopic Detection of Submucosal Invasive Cancer in Colorectal Polyps
Colorectal cancer (CRC) is a leading cause of death in the Western world. It can be effectively prevented by removal of pre-malignant polyps (polypectomy) during colonoscopy.
- Trial name
- NCT05191095
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- University Hospital, Ghent
Lung Cancer
Early Detection of Lung Cancer
This research trial studies the long term follow-up for early detection of lung cancer in current or former smokers. Following up on smokers by collecting and analyzing specimens in the laboratory, performing chest computed…
- Trial name
- NCT03181256
- Testing
- Biospecimen Collection, Pulmonary Function Test, Computed Tomography (CT)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Supratentorial Brain Tumor
Influence of Intracranial Lesions on Bispectral Index
The purpose of this study is to assess whether BIS values at return of consciousness are different in patients with or without brain tumors.
- Trial name
- NCT01060631
- Testing
- BIS values at return of consciousness in patients + predicted and measured propofol plasma concentrations
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- University Medical Center Groningen
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