Clinical trials: Developing Countries
Cognitive Dysfunction, Sleep Deprivation
Effects of Partial Sleep Deprivation on Cognitive Function of Anesthesiologists
The purpose of this study was to evaluate differences in cognitive functions at baseline and following night shift at a trauma center among faculty anesthesiologists.
- Trial name
- sleep (NCT03784560)
- Testing
- The Psychomotor Vigilance Task (PVT), Epworth Sleepiness Scale, Karolinska sleeping scale
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Fetal Distress, Stillbirth
Introducing Fetal Scalp Stimulation as an Adjunct to Intermittent Auscultation in Low-Resource Settings.
This study is a pilot study taking place in Moshi, Tanzania at the Kilimanjaro Christian Medical Centre (KCMC). The study aims to introduce fetal scalp stimulation into the intermittent auscultation protocols at KCMC, and to…
- Conditions
- Fetal Distress, Stillbirth, Birth Asphyxia, Acidosis
- Trial name
- NCT02862925
- Testing
- Fetal Scalp Stimulation
- Where
- Tanzania
- Volunteers
- 550 people
- Sponsor
- Duke University
Health Insurance
Experimental Study to Assess Interventions Aimed at Improving the Equity Impact of Community-Based Health Insurance
The purpose of this study is to assesses interventions aimed at improving the distributional impact of a community based health insurance scheme in rural India.
- Trial name
- NCT00421629
- Testing
- After-sales service and supportive supervision (AfterSS), Prospective reimbursement (PR), Both (AfterSS and PR)
- Where
- India
- Volunteers
- 688 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Postpartum Hemorrhage
Misoprostol for Secondary Prevention of Postpartum Hemorrhage at the Community Level in India
This study compares two community-level strategies: selective administration of 800 mcg sublingual misoprostol to women at 350 mL blood loss for secondary prevention of postpartum hemorrhage (PPH) with universal use of 600 mcg…
- Trial name
- NCT01462422
- Testing
- Misoprostol
- Where
- India
- Volunteers
- 3,032 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Sexual Abstinence, HIV
Affecting the Epidemiology of HIV in Uganda
The investigators propose to develop a comprehensive, text messaging-based HIV prevention program for Ugandan adolescents 18-22 years of age.
- Conditions
- Sexual Abstinence, HIV, Contraceptive Usage
- Trial name
- NCT02729337
- Testing
- ITG (In This Together)
- Where
- Uganda
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Center for Innovative Public Health Research
Infective Endocarditis
Infective Endocarditis in Developing Countries, a Prospective, Observational, Multicentre Study
Introduction. Comprehensive data on infective endocarditis in developing countries are scarce. Objectives: Description of the characteristics (clinical and microbiological) and assessment of the outcomes of infective endocarditis…
- Trial name
- EndoDev (NCT02128139)
- Where
- 6 sites in Fiji, Laos and 3 more
- Volunteers
- 300 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Nutritional Status
Impact of Exclusive Breast-Feeding in Guinea Bissau
Exclusive breastfeeding is promoted by the World Health Organization (WHO) with the aim of improving infant health. The specific objective of the study was to examine the effect of exclusive breast-feeding on morbidity and…
- Trial name
- NCT00131625
- Testing
- Health education according to WHO recommendations
- Where
- Guinea-Bissau
- Volunteers
- 1,500 people
- Sponsor
- Bandim Health Project
HIV Infections, Pregnancy
Nevirapine Plus Zidovudine to Prevent Perinatal HIV in Thailand
The purpose of this study was to assess the efficacy of a single dose of the drug nevirapine (NVP) given to pregnant women at onset of labor and to their infant 48-72 hours after birth in addition to standard oral zidovudine (ZDV…
- Trial name
- NCT00398684
- Testing
- Single dose nevirapine to the mother and to the child
- Where
- Thailand
- Volunteers
- 1,792 people
- Sponsor
- Institut de Recherche pour le Developpement
Other Specified Effects of Reduced Temperature
Field Application of Shanchol in Adults in Bangladesh
Background: Cholera is a public health problem globally and in Bangladesh and its prevention is important. Despite recent availability of an effective and affordable oral cholera vaccine (OCV), its field application remains a…
- Trial name
- NCT01762930
- Testing
- Shanchol
- Where
- Bangladesh
- Volunteers
- 1,015 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Infant, Newborn, Diseases, Sepsis
Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn
The purpose of this study is to evaluate whether use of the disinfectant chlorhexidine administered to the birth canal during labour and newborn at delivery can protect a woman and her baby from bacterial infections after birth.
- Conditions
- Infant, Newborn, Diseases, Sepsis, Puerperal Infection
- Trial name
- NCT00136370
- Testing
- Chlorhexidine, Birth canal wipe, sterile water external genital wipe
- Where
- South Africa
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Cardiovascular Disease
Scaling-up Packages of Interventions for Cardiovascular Disease Prevention in Selected Sites in Europe and Sub-Saharan Africa: An Implementation Research
Cardiovascular disease is the leading cause of death in the world. 17.5 million people died in 2012 due to a cerebrovascular disease (31% of all causes of death).
- Trial name
- SPICES_PHASE_1 (NCT03154736)
- Testing
- Interview
- Where
- 21 sites in France
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Low Birth Weight
Efficacy of Continuous Skin to Skin Care (Technique Kangaroo: TK) After Birth for Low Birth Weight (LBW) Infants and Their Mothers in Developing Countries
The purpose of this study is to examine the efficacy of Technique Kangourou (TK) between low birth weight (LBW) infants and their mothers started as soon as possible within 24 hours after birth in developing country.
- Trial name
- EtudeTK (NCT00531492)
- Testing
- TK as soon as possible within 24 hours after birth, Conventional care
- Where
- Madagascar
- Volunteers
- 73 people
- Sponsor
- Foundation for Advanced Studies on International Development
Child Malnutrition
Developing Low-Cost Universal Malnutrition Screening for Low Income Countries - the MAMMS Trial
Acute malnutrition affects 52 million children, costs $2.1 trillion globally, and contributes to 45% of deaths among children under five years of age.
- Trial name
- NCT03967015
- Testing
- Maternal Administered Malnutrition Monitoring System (MAMMS)
- Where
- 3 sites in Kenya
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Washington
Telemedicine, Primary Health Care
Satellite-supplementation of Medical Outreach Clinics: a Feasibility Study
Much of the basic general medical care and chronic disease management in rural Honduras comes from groups of volunteers setting up temporary clinics run by volunteers.
- Conditions
- Telemedicine, Primary Health Care, Developing Countries, Diagnosis
- Trial name
- NCT01821014
- Testing
- Telemedicine, In-person physician interaction
- Where
- Honduras
- Volunteers
- 144 people
- Sponsor
- Mayo Clinic
Omphalitis
Chlorhexidine Cord Care for Newborn Infants in Kenya
Studies in several countries with a high rate of death of infants during the first week of life have found a reduction in infection and mortality when chlorhexidine is applied to the umbilical cord stump by a health worker within…
- Trial name
- NCT02624622
- Testing
- Chlorhexidine application to cord by mother, Chlorhexidine application by CHW
- Where
- United States
- Volunteers
- 576 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Malaria, Pneumonia
Study of Post-Training Supports for Health Workers in Benin
The objective of this study was to determine the effectiveness and cost-effectiveness of a package of interventions to support health workers in Benin (in West Africa) who had been trained to use Integrated Management of…
- Conditions
- Malaria, Pneumonia, Diarrhea, Measles
- Trial name
- NCT00510679
- Testing
- Health worker supports (supervision, job aids, incentives)
- Where
- Benin
- Volunteers
- 1,577 people
- Sponsor
- Centers for Disease Control and Prevention
Postpartum Hemorrhage, Anemia
Misoprostol for the Prevention of Postpartum Hemorrhage in Rural Pakistan
This community-based trial will study misoprostol for the prevention of postpartum hemorrhage in rural Pakistan. Traditional birth attendants assisting home deliveries will administer study tablets (600 mcg oral misoprostol or…
- Trial name
- NCT00120237
- Testing
- Misoprostol
- Where
- Pakistan
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Hearing Loss, Bone Anchored Hearing Aids
Attitude Change Of Hearing Health Professionals On Bone-Anchored Hearing Devices Over Time In a Developing Country
This study aims to examine shifts in attitudes about bone-anchored hearing instruments (BAHIs) among hearing health professionals over a period of time.
- Trial name
- NCT06215599
- Testing
- Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 243 people
- Sponsor
- Pamukkale University
Hypothermia
Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part II
The overall hypothesis is that plastic bags used in combination with WHO thermoregulation care will reduce the incidence of hypothermia in preterm/low birth weight and full term infants when compared to routine WHO…
- Trial name
- NCT01604421
- Testing
- Thermoregulation-standard care, Thermoregulation with plastic bag
- Where
- Zambia
- Sponsor
- University of Alabama at Birmingham
Poisoning by Carbon Monoxide From Domestic Fuels, Respiratory Conditions Due to Other External Agents
Feasibility Intervention Trial of Two Types of Improved Cookstoves in Three Developing Countries
The underlying concept behind this feasibility trial is to achieve a reduction in indoor smoke from biomass fuels and minimize changes in cooking practices such that it prompts one of the two improved, ventilated cookstoves to be…
- Trial name
- NCT01686867
- Testing
- Improved, ventilated cookstove
- Where
- 3 sites in Kenya, Nepal and 1 more
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health