Clinical trials: Developing Countries
Diabetes Mellitus, Diabetes
Conversation Map and Diabetes in Pakistan
Background Diabetes is recognized as an important cause of premature death and disability. Non-clinical interventions play an important role in the control of diabetes and the prevention of its associated complications.
- Conditions
- Diabetes Mellitus, Diabetes, Self Efficacy, Diabetes Mellitus, Type 2
- Trial name
- DAMP (NCT03747471)
- Testing
- Diabetic Conversation Map
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Rubina Qasim
Haemophilia, Developing Countries
Non Substitutive Strategies to Improve Haemophilia Care in Developing Countries. Experience in Ivory Coast.
This study aims to make an inventory of the condition and care of patients with haemophilia and carriers for haemophilia in Ivory Coast and to promote the use non substitutive strategies that are not costly and available in Ivory…
- Trial name
- NCT03054662
- Testing
- Education, Improve biological diagnosis and follow-up of haemophilia, Implement haemostatic non substitutive care of haemophilia
- Where
- Côte d’Ivoire
- Volunteers
- 142 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Infant Malnutrition, Nutrition Knowledge
Improving the Nutrition Status of Infants in South-Western Uganda
Undernutrition and growth restriction due to poor diet and inadequate nutrient intake continues to be a global challenge, particularly in the developing countries including Uganda.
- Conditions
- Infant Malnutrition, Nutrition Knowledge, Growth, Cognitive Development
- Trial name
- CHNUDEV (NCT02098031)
- Testing
- Improving nutrition knowledge among mothers
- Where
- Uganda
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Postpartum Hemorrhage
Misoprostol for the Treatment of Postpartum Hemorrhage
The purpose of this study is to test whether misoprostol is as effective as oxytocin for treating primary postpartum hemorrhage (PPH) with uterine atony as the suspected cause in two circumstances: 1) where women have received…
- Trial name
- NCT00116350
- Testing
- Misoprostol, Oxytocin
- Where
- 6 sites in Burkina Faso, Ecuador and 3 more
- Volunteers
- 1,786 people
- Sponsor
- Gynuity Health Projects
Malaria
Revaccination of Young Children With Bacille Calmette Guerin (BCG) Vaccine
BCG has marked immune stimulatory effects in both animal and human studies and observational studies suggest that BCG is associated with a non-specific reduction in mortality in areas with high infant and child mortality.
- Trial name
- NCT00126217
- Testing
- Bacille Calmette Guerin (BCG)
- Where
- Guinea-Bissau
- Volunteers
- 2,871 people
- Sponsor
- Bandim Health Project
Suggamadex, Surgery for Congenital Heart Disease
Suggamadex and Fast-track Cardiac Anesthesia in a Developing Country
The purpose of this study is to retrospectively review our preliminary experience during a surgical trip to Tuxtla, Mexico, using suggamadex to reverse neuromuscular blockade following CPB and cardiac surgery for repair of CHD in…
- Trial name
- NCT02704351
- Testing
- Surgery
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Joseph D. Tobias
Knee Arthroplasty, Total, Hypothermia
Predictors and Outcomes of Intraoperative Hypothermia in Patients Undergoing Knee Arthroplasty
The study is designed to retrospectively assess the risk factors associated with intra-operative hypothermia in patients undergoing total knee arthroplasty from January 2016 to December 2017 at Aga Khan University and also…
- Trial name
- NCT04575246
- Volunteers
- 286 people
- Sponsor
- Aga Khan University
HIV, HIV Infections
Evaluation of Conditional Cash Transfers to Increase Retention in PMTCT Services in Akwa Ibom State, Nigeria
A randomized controlled trial will be conducted to assess the effectiveness of conditional cash transfers (CCTs) at increasing retention in prevention of mother-to-child transmission (PMTCT) services specifically, in relation to…
- Conditions
- HIV, HIV Infections, Pregnancy, Infant, Newborn, Diseases
- Trial name
- NCT02447159
- Testing
- Conditional Cash Transfers
- Where
- 3 sites in Nigeria
- Volunteers
- 554 people
- Sponsor
- University of California, San Francisco
Soft Tissue Injuries
"Enhancing Surgical Safety in Developing Nations: Investigating Antibiotics' Role in Hand Surgeries."
The goal of this clinical trial is to compare the use of antibiotics with no use in people undergoing soft tissue hand surgery in developing countries.
- Trial name
- NCT05990842
- Testing
- Antibiotic
- Volunteers
- 51 people
- Sponsor
- Marcos Felipe Marcatto de Abreu
Common Bile Duct Calculi
The Cost Effectiveness of Endoscopic Ultrasound ( EUS ) Based Strategy in Diagnosis of Common Bile Duct Stones
Multiple reports in the literature showed the efficacy of EUS comparable to ERCP in the diagnosis of common bile duct ( CBD ) stone.
- Trial name
- NCT02349568
- Testing
- High risk group, Intermediate risk group
- Where
- Thailand
- Volunteers
- 141 people
- Sponsor
- Prince of Songkla University
Home Mechanical Ventilation, Prolonged Mechanical Ventilation
Patient Characteristics, Feasibility, and Outcomes of a Home Mechanical Ventilation Program in a Developing Country
This study aims to describe the patient characteristics, feasibility, and outcomes of an home mechanical ventilation (HMV) program at a university hospital in Thailand.
- Trial name
- NCT02927613
- Where
- Thailand
- Volunteers
- 12 people
- Sponsor
- Thammasat University
Infective Endocarditis
Infective Endocarditis in Developing Countries, a Prospective, Observational, Multicentre Study
Introduction. Comprehensive data on infective endocarditis in developing countries are scarce. Objectives: Description of the characteristics (clinical and microbiological) and assessment of the outcomes of infective endocarditis…
- Trial name
- EndoDev (NCT02128139)
- Where
- 6 sites in Fiji, Laos and 3 more
- Volunteers
- 300 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Maternal Morbidity and Mortality, Stillbirth and Neonatal Mortality
Emergency Obstetric and Neonatal Care: The EmONC Trial
The objective of this cluster randomized controlled trial is to reduce maternal and neonatal mortality by increasing access to and improving the quality of obstetric and neonatal care for pregnant women in study clusters.
- Trial name
- EmONC (NCT01073488)
- Testing
- Community Mobilization, HBLSS and facility improvement
- Where
- 7 sites in Argentina, Guatemala and 4 more
- Volunteers
- 267,181 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Streptococcal Infections, Pharyngitis
Treatment of Group A Beta Hemolytic Streptococcal Pharyngitis in Children in Low Resource Settings
The purpose of this study was to compare the microbiological effects of two different treatments: a single dose of intramuscular benzathine penicillin G (IM BPG) vs.
- Trial name
- TOPS (NCT01156740)
- Testing
- Penicillin G, Benzathine, Amoxicillin
- Where
- 3 sites in Brazil, Croatia and 1 more
- Volunteers
- 558 people
- Sponsor
- Johns Hopkins University
Healthy Participants, Non-anemic Children
Ferrous Fumarate and Ferric Pyrophosphate as Food Fortificants in Developing Countries
Iron fortification of foods is usually considered the most cost-effective approach to prevent iron deficiency. However, iron is the most difficult mineral to add to foods.
- Conditions
- Healthy Participants, Non-anemic Children, Helicobacter Pylori Infection
- Trial name
- NCT00867867
- Testing
- Ferrous fumarate, Ferric pyrophosphate
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Omphalitis
Chlorhexidine Cord Care for Newborn Infants in Kenya
Studies in several countries with a high rate of death of infants during the first week of life have found a reduction in infection and mortality when chlorhexidine is applied to the umbilical cord stump by a health worker within…
- Trial name
- NCT02624622
- Testing
- Chlorhexidine application to cord by mother, Chlorhexidine application by CHW
- Where
- United States
- Volunteers
- 576 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Anxiety Disorder/Anxiety State, Depressive Disorder/Psychology
Adapting Mental Health Interventions for War-Affected Youth Through Employment Programs
The research will first examine data obtained from YRI participants to investigate effects of the group sessions on psychosocial functioning outcomes in youth aged 15 - 24.
- Conditions
- Anxiety Disorder/Anxiety State, Depressive Disorder/Psychology, Social Problems/Psychology, Violence, Non-accidental
- Trial name
- NCT02561949
- Testing
- YRI, Income generating activity program
- Where
- Sierra Leone
- Volunteers
- 80 people
- Sponsor
- Boston College
Postpartum Hemorrhage, Anemia
Misoprostol for the Prevention of Postpartum Hemorrhage in Rural Pakistan
This community-based trial will study misoprostol for the prevention of postpartum hemorrhage in rural Pakistan. Traditional birth attendants assisting home deliveries will administer study tablets (600 mcg oral misoprostol or…
- Trial name
- NCT00120237
- Testing
- Misoprostol
- Where
- Pakistan
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Health Care Economics, Child Health
Laos Out-Of-Pocket Costs: an Observational Study on the Impact of Severe Childhood Illness on the Health, Wealth and Wellbeing of Household Members in Laos
This will be a prospective longitudinal study of children attending hospital for treatment of a severe illness with community follow-up in Lao People's Democratic Republic (Lao PDR).
- Conditions
- Health Care Economics, Child Health, Cost of Illness, Burden of Illness
- Trial name
- LOOP (NCT05239104)
- Testing
- No intervention
- Where
- Laos
- Volunteers
- 400 people
- Sponsor
- Murdoch Childrens Research Institute
Acute Myeloid Leukemia
Feasibility Study of Intermediate Doses of ARA-C With Autologous SCT as Consolidation of Low/Intermediate-risk AML
Create a network of institutions in developing countries that will perform AML diagnosis, risk classification, treatment, supportive care and follow-up evaluation according to a common protocol and will register data using common…
- Trial name
- ICAML2015 (NCT03023384)
- Where
- 6 sites in Brazil
- Volunteers
- 547 people
- Sponsor
- International Consortium on Acute Leukemias