Clinical trials: Development
Language Development, Behavior, Child
Literacy Promotion for Latinos Study
This study tests the extent to which tailored outreach text messages that provide a cue to action and an intervention that enhances access to poverty-reducing resources, in combination with standard primary care literacy…
- Conditions
- Language Development, Behavior, Child, Parenting, Literacy
- Trial name
- NCT04609553
- Testing
- Usual care including ROR, Text messages, Connection to community resources
- Where
- United States
- Volunteers
- 662 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Language Development Disorders
Kindergarten Children Acquiring Words Through Storybook Reading
Children with Specific Language Impairment (SLI) are slower to learn new words than their peers, placing them at risk for academic failure.
- Trial name
- KAWStory (NCT03586479)
- Testing
- Interactive storybook reading
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Kansas
Adolescent Development
Jump-In: Building Better Bones
The Jump-In study will prospectively assess the effects of impact exercise on skeletal development in young girls, including bone mass, bone mineral density, and bone geometry.
- Trial name
- NCT00729378
- Testing
- Skeletal loading
- Where
- United States
- Volunteers
- 509 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Child Abuse, Child Neglect
Promoting Resilience and Lowering Risk in Early Childhood
An intervention study to provide in-the-moment parenting tips with the goal of increasing healthy parent-child interactions leading to resiliency in high-risk children.
- Conditions
- Child Abuse, Child Neglect, Parenting, Child Development
- Trial name
- NCT05479734
- Testing
- mHealth Intervention
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Oklahoma
Obesity, Infant, Language Development
Music and Child Health and Development
The goal of this clinical trial is to learn about the effects of a music enrichment program on the quality of parent child interactions, a child's motivation to eat, and a child's language environment in 9 to 24 month-old…
- Conditions
- Obesity, Infant, Language Development, Parent-Child Relations
- Trial name
- NCT05868811
- Testing
- Music Together, Play Group
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Depression, Child Development
Healthcare Providers as Trusted Messengers to Increase Receipt of Tax Credits Among Low-income Families
The purpose of this study is to pilot test the feasibility and preliminary efficacy of healthcare provider referrals to a tax filing app within parent-child health programs to test whether such referrals can increase receipt of…
- Conditions
- Depression, Child Development, Stress, Physical Illness
- Trial name
- NCT05612685
- Testing
- Healthcare provider referral to a tax filing app
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Developmental Language Disorder, Specific Language Impairment
Retrieval-Based Word Learning in Developmental Language Disorder
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder, Specific Language Impairment, Language Development
- Trial name
- NCT05325333
- Testing
- Retrieval-based word learning: Expanding retrieval practice schedule, Retrieval-based word learning: Standard retrieval practice schedule
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Purdue University
Developmental Language Disorder, Specific Language Impairment
Retrieval-Based Word Learning in Developmental Language Disorder: Verb Learning
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder, Specific Language Impairment, Language Development
- Trial name
- NCT06001866
- Testing
- Retrieval-based verb learning: Repeated Spaced Retrieval condition, Retrieval-based verb learning: Repeated Study condition
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Purdue University
Child Development
Added Sugar Intake and Brain Structure and Function
The purpose of this study is to learn if there is a relationship between added sugar intake during pregnancy, infancy, and toddlerhood and the brain's structure and function at 5-6 years old.
- Trial name
- GAINS BRAINS (NCT06640829)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Congenital Adrenal Hyperplasia, Hyperplasia
Subcutaneous Hydrocortisone Children With Congenital Adrenal Hyperplasia
This is an open-label, non-randomized, single arm proof-of concept feasibility trial comparing standard oral hydrocortisone (HC) treatment with a six-week intervention of interval bolus delivery (pulsatile) of subcutaneous (SQ)…
- Conditions
- Congenital Adrenal Hyperplasia, Hyperplasia, Adrenal Hyperplasia, Congenital Disorders
- Trial name
- NCT03718234
- Testing
- Subcutaneous hydrocortisone
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Minnesota
Infant Development, Hemiplegia
CIMT and taVNS for Hemiplegia in Infants
Newborns who are born premature or suffer brain injury at birth are at risk for motor problems that may cause weakness in reaching and grasping on one side of the body.
- Conditions
- Infant Development, Hemiplegia, Constraint Induced Movement Therapy
- Trial name
- NCT05101707
- Testing
- transcutaneous auricular vagus nerve stimulation, Constraint induced movement therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Medical University of South Carolina
Embryonic Development, Embryo Morphokinetics
Embryo Culture Under Constant 5% vs Gradient 8%, 5%, 2% Oxygen Concentration
The purpose of this study is to investigate the development of human embryos in vitro under two different oxygen concentrations; a static 5% during all five days of culture or under an oxygen gradient, starting with 8% from day-0…
- Conditions
- Embryonic Development, Embryo Morphokinetics, Embryo Morphometry
- Trial name
- NCT05898178
- Testing
- Experimental intervention: 8-5-2% oxygen gradient concentration in the incubator
- Where
- Slovenia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Maribor
Infant Development
Mobile Health Intervention to Promote Positive Infant Health Outcomes in Guatemala
Promoting optimal development for children at risk in low- and middle-income countries (LMICs) is an important global health priority.
- Trial name
- NCT05106894
- Testing
- smartphone application to promote nurturing care, printed caregiving materials
- Where
- Guatemala
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Child Development, Health Services Research
Achieving My Potential: A Randomized, Controlled Trial of a Telephone-Based Developmental Care Coordination System
The proposed project is a randomized controlled trial of a telephone-based early childhood developmental care coordination system, in partnership with 2-1-1 Los Angeles County (211LA), part of a national network of 2-1-1 call…
- Trial name
- AMP (NCT04118452)
- Testing
- Telephone-based early childhood developmental care coordination
- Where
- 4 sites in United States
- Volunteers
- 565 people
- Sponsor
- University of California, Los Angeles
Epilepsy; Seizure, Neuromuscular Diseases
North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2
The "North Carolina Clinical Genomic Evaluation by Next-gen Exome Sequencing, 2 (NCGENES 2)" study is part of a larger consortium project investigating the clinical utility, or net benefit of an intervention on patient and family…
- Conditions
- Epilepsy; Seizure, Neuromuscular Diseases, Brain Malformation, Intellectual Disability
- Trial name
- NCGENES2 (NCT03548779)
- Testing
- Pre-visit prep, usual care + exome seq
- Where
- 3 sites in United States
- Volunteers
- 548 people
- Sponsor
- University of North Carolina, Chapel Hill
Autism, Development Delay
Culturally-Responsive Curriculum for Caregivers With Children at Autism Likelihood
The goal of this clinical trial is to examine how helpful and relevant the Family Care Project workbook is for families from culturally and linguistically diverse backgrounds who have a young child at autism likelihood.
- Trial name
- NCT06314438
- Testing
- Family Care Project
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Washington
Gross Motor Development Delay, Social Skills
SKIPping With PAX: An Integrated Gross Motor and Social-Emotional Skill Intervention
The purpose of this study was to test the effects of an integrated intervention on the gross motor and social-emotional development of rural preschool boys and girls.
- Conditions
- Gross Motor Development Delay, Social Skills, Social Behavior, Sedentary Behavior
- Trial name
- NCT04656990
- Testing
- Integrated Intervention
- Where
- United States
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Autism Spectrum Disorder (ASD)
Omega-3 Fatty Acids Monotherapy in Children and Adolescents With Autism Spectrum Disorders
The primary aim of this study is to examine the efficacy and tolerability of short-term omega-3 fatty acids monotherapy in youth with Autism Spectrum Disorders (ASD).
- Trial name
- NCT01248130
- Testing
- Omega-3 Fatty Acid
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Massachusetts General Hospital
Autism, Autism Spectrum Disorder
Services to Enhance Social Functioning in Adults With Autism Spectrum Disorders
The purpose of this study is to test a novel, three-part cognitive behavioral treatment strategy to improve social functioning in adults with autism spectrum disorder.
- Conditions
- Autism, Autism Spectrum Disorder, Autistic Disorder, Asperger Syndrome
- Trial name
- NCT04788537
- Testing
- Training to Understand and Navigate Emotions and Interactions (TUNE In)
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Development Delay, Behavior Problem
The Pro-Parenting Study: Helping Parents Reduce Behavior Problems in Preschool Children With Developmental Delay
The Pro-Parenting Study seeks to determine the added benefit of targeting both parenting stress and parent management strategies to more effectively reduce behavior problems among children with developmental delay (DD).
- Trial name
- NCT03599648
- Testing
- BPT-M, BPT-E
- Where
- 2 sites in United States
- Volunteers
- 959 people
- Sponsor
- University of Oregon