Clinical trials: Developmental Delay Disorders
Autistic Disorder
Research in Autism: Parent Intervention
The purpose of this research project was to systematically compare two widely used types of intervention programs for children with autism within a parent training model.
- Trial name
- NCT01258465
- Testing
- Pivotal Response Training, Picture Exchange Communication System
- Where
- 2 sites in United States
- Volunteers
- 39 people
- Sponsor
- University of California, San Diego
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
Eye Tracking as a Predictor of Methylphenidate Response in Autism With ADHD
The overall goal of this research is to use neurophysiological measures to profile strengths and deficits for Attention Deficit Hyperactivity Disorder co-morbidity in Autism Spectrum Disorder to clarify diagnosis and to predict…
- Trial name
- SAT (NCT02874690)
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism Spectrum Disorder
Fatty Acid Supplementation in Children With ASD
The purpose of this study is to examine how fatty acid supplementation alters biological signatures in children with ASD
- Trial name
- Omega Heroes (NCT03550209)
- Testing
- LCPUFA Oil Supplement
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Sarah Keim
Autism Disorder, Multiple Disabilities
Impact and Determinants of Success of a Mobile Multidisciplinary Intervention System Specialized in Pain Management for Patients With Moderate to Severe Intellectual Development Disorder, Isolated or Associated With an ASD or Multiple Disability
Pain is described by patients with a Neurodevelopmental Disorder (NDD), including Autism Spectrum Disorder (ASD), Intellectual Development Disorder (IDD) or multiple disabilities, and the family as one of the main associated…
- Conditions
- Autism Disorder, Multiple Disabilities, Pain, Intellectual Developmental Disorder
- Trial name
- MoDIDol (NCT07302048)
- Testing
- MoDIDol intervention
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Brest
Autism Spectrum Disorder, Intellectual Disability
Heart Rate Informed Changes in Care for Non-Communicating Patients
The overarching aim is to generate knowledge to reduce incidence of pain in non-verbal patients' everyday life. The trial will 1) evaluate how HR can be used to identify potentially painful care procedures that should be…
- Conditions
- Autism Spectrum Disorder, Intellectual Disability, Communication, Nonverbal
- Trial name
- NCT05738278
- Testing
- HR-informed change in routine, Delayed HR-informed specific change in routine
- Where
- 2 sites in Norway
- Volunteers
- 38 people
- Sponsor
- University of Oslo
Autism, Autism Spectrum Disorder
Neural and Behavioral Outcomes of Social Skills Groups in Children With Autism Spectrum Disorder (ASD)
The purpose of this study is to compare two different treatment approaches to social skills groups for high-functioning children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT01190917
- Testing
- Cognitive Behavioral Therapy (CBT), Play Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Other Developmental Disorders of Speech and Language
A Speech Sound and Phonemic Awareness Intervention in Flemish Early Childhood Education
The language intervention 'Kaatje Klank' is designed for stimulating the speech production and speech perception skills of 4-year-olds in an early childhood educational setting, in order to stimulate early literacy skills.
- Trial name
- NCT02313025
- Testing
- speech sound intervention, World-project
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Neurodevelopmental Disorders, Autism Spectrum Disorder
Characterization of Social Cognition Profiles in Children and Adolescents With Neurodevelopmental Disorders: a Clinical Study Using a Multidimensional Battery
In France, more than one in ten school-aged children suffers from a mental health disorder, and half of these disorders appear before the age of 14. Yet, only half of affected children receive appropriate support.
- Conditions
- Neurodevelopmental Disorders, Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Atypical Neurodevelopmental Disorder
- Trial name
- COGSO (NCT07439276)
- Testing
- Test, Questionnaires
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder, Temporomandibular Joint Disorders
Balance, TMJ, Social Adaptive Assessment in Individuals With Autism Spectrum Disorder
The aim of our study is to evaluate temporomandibular joint (TMJ), cervical posture, balance, dual-task performance, and social adaptation skills in individuals with autism.
- Conditions
- Autism Spectrum Disorder, Temporomandibular Joint Disorders, Postural; Defect
- Trial name
- NCT06721104
- Testing
- Dual Task, Functional Balance, Social Adaptation Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Autism Spectrum Disorder
Cognitive Behavioral Therapy for Core Autism Symptoms in School-Aged Children: A Randomized, Controlled Trial
This study is designed to examine the efficacy of a cognitive behavioral therapy (CBT) program for treating core autism symptoms, social and emotional problems, and adaptive behavior deficits in children with autism spectrum…
- Trial name
- BIACA-2 (NCT00789932)
- Testing
- cognitive behavioral therapy, Usual community care
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Autistics Children
Efficiency of Bumetanide in Autistic Children
The purpose of this study is to determine if a treatment by bumetanide presents an efficiency at the level of the neuronal maturation in the autism
- Trial name
- BUMEA (NCT01078714)
- Testing
- bumetanide
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Brest
Circadian Rhythm Sleep Disorders, Non-24 Hour Sleep-Wake Disorder
Study of the Pharmacokinetics and Safety of Tasimelteon in Children and Adolescents
Open-label Study to Investigate the Pharmacokinetics and Safety of Tasimelteon in Children and Adolescents.
- Conditions
- Circadian Rhythm Sleep Disorders, Non-24 Hour Sleep-Wake Disorder, Autism Spectrum Disorder, Smith-Magenis Syndrome
- Trial name
- NCT02776215
- Testing
- tasimelteon
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Vanda Pharmaceuticals
Genetic Disorder, Asperger Disorder
Pediatric Patients With Metabolic or Other Genetic Disorders
Background: Some patients with unusual genetic conditions are referred to the National Institutes of Health (NIH). They may not be eligible to join current research studies.
- Conditions
- Genetic Disorder, Asperger Disorder, Autism Spectrum Disorder, Fragile X Syndrome
- Trial name
- NCT02769949
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Autism Spectrum Disorder, Dexmedetomidine
Esketamine Combined With Dexmedetomidine Sedation in Head MRI Examination of Children With Autism Spectrum Disorder
Objective: To investigate the use of ketamine combined with dexmedetomidine for sedation in children with autism spectrum disorder, Methods:aged 2-6 years,, ASA grade I or II.
- Conditions
- Autism Spectrum Disorder, Dexmedetomidine, Esketamine, Sedation
- Trial name
- NCT06633315
- Testing
- low dos dexmedetomidine, high dos dexmedetomidine, dexmedetomidine and esketamine
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Maternal and Child Health Hospital of Hubei Province
Autism, Developmental Delay Disorders
Project EARLY: Engagement, Assessment, Referral, & Linkage for Young Children
Emerging evidence demonstrates that Autism Spectrum Disorder (ASD) can be reliably diagnosed by age two, and that early identification and intervention can improve outcomes.
- Trial name
- NCT02359084
- Testing
- Family Navigation, Conventional Care Management
- Where
- 10 sites in United States
- Volunteers
- 340 people
- Sponsor
- Boston University
Global Developmental Delay
Workshops for Children With Global Developmental Delays
To investigate the therapeutic effects of family workshops on children with global developmental delays and their parents by the analysis of the previously conducted workshops.
- Trial name
- NCT05418933
- Testing
- Family workshop
- Where
- Taiwan
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Autism Spectrum Disorder
Tele-rehabilitation Program: An Innovative and Sustainable Early Intervention Service for Children With Autism Spectrum Disorders
In Singapore, Autism Spectrum Disorders (ASD) is ranked number one in disease burden for children 0-14 years of age. The Child Development Unit at the National University Hospital serves 3000 children annually, of which 25-30% of…
- Trial name
- NCT05792449
- Testing
- Foundational Skills Curriculum, Foundational Skills Curriculum - Telerehabilitation
- Where
- Singapore
- Volunteers
- 200 people
- Sponsor
- National University Hospital, Singapore
Autism Spectrum Disorder
Gut Microbiome Characteristics and Neurodevelopmental Functioning in Children With Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is a neurodevelopmental condition that affects communication, behavior, sensory processing, and daily functioning.
- Trial name
- GAIN-ASD (NCT07646808)
- Where
- India
- Volunteers
- 600 people
- Sponsor
- Saveetha University
Autism
A Strength-Based Employment Maintenance Program for Individuals on the Autism Spectrum
The investigators are looking to evaluate how effective a training program that focuses on character strengths may be in improving job maintenance skills in young adults.
- Trial name
- NCT06255925
- Testing
- KF-STRIDE® Into Work!
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kessler Foundation
Neurodevelopmental Disorders, Intellectual Disability
Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome
The goal of this observational study is to learn about the impact of the diabetes drug glibenclamide (glyburide) on neurodevelopment in individuals with iDEND (developmental delay, epilepsy and neonatal diabetes) due to the V59M…
- Conditions
- Neurodevelopmental Disorders, Intellectual Disability, Development Delay, ADHD
- Trial name
- iDEND (NCT05751525)
- Testing
- Sulfonylurea
- Where
- 4 sites in United States, Italy and 2 more
- Volunteers
- 21 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust