Clinical trials: Developmental Language Disorders, open to volunteers
Developmental Language Disorder, Language Impairment
The Relationship Between Child Language Proficiency and Language of Treatment on the Outcomes of Bilingual Children with Developmental Language Disorder
Of the 12 million children in the USA growing up bilingual, about 1 million experience Developmental Language Disorder (DLD), a disorder in language learning and use.
- Trial name
- NCT06085300
- Testing
- Sentence recast
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Houston
Down Syndrome
How Simplified Language Affects Comprehension and Learning in Young Children With Down Syndrome
The long-term study goal is to experimentally evaluate the components (and likely active ingredients) of early language interventions for young children with Down syndrome (DS).
- Trial name
- NCT06951516
- Testing
- Linguistic simplification
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Michigan State University
Language Delay, Language Development
Combined Oral Motor Stimulation and Language on Preterm Infant Feeding
This is a randomized controlled trial to study an oromotor stimulation in combination with a reading curriculum in the NICU among preterm infants using oral muscle exercises, Language Environment Analysis (LENA) recordings…
- Conditions
- Language Delay, Language Development, Feeding; Difficult, Newborn, Mother-Infant Interaction
- Trial name
- NCT05861531
- Testing
- Oromotor stimulation, Reading curriculum, LENA recording
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Language Development Disorders
Virtual Reality-supported Language Intervention for Preschool Children With DLD
This study aims to test the effectiveness of virtual reality-supported speech therapy in improving basic language skills in children aged 3 to 6 years diagnosed with Developmental Language Disorder (DLD).
- Trial name
- NCT07438639
- Testing
- Virtual Reality Rehabilitation System (VRRS), Taditional Speech Therapy
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Stutter, Stuttering, Adult
Organization and Development of Motor Cortical Circuits for Speech Production in Stuttering
The overall objective of this study is to examine inter effector areas (IEAs) activity and functional connectivity during continuous speech production in stuttering adults.
- Conditions
- Stutter, Stuttering, Adult, Stuttering, Stuttering, Developmental
- Trial name
- NCT07180628
- Testing
- Speech Production During functional magnetic resonance imaging (MRI)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Hearing Impaired Children
Artificial Grammar Learning in Children Who Are Deaf or Hard-of-Hearing: Stimulus Length Effect
The goal of this basic experimental study involving humans (BESH) clinical trial is to examine how stimulus length affects grammar learning in children who are deaf or hard-of-hearing and who primarily use spoken language.
- Trial name
- NCT07782567
- Testing
- Short linguistic content, Long linguistic content
- Volunteers
- 30 people
- Sponsor
- University of Illinois Chicago
Autism Spectrum Disorder
Tool for Evaluating the Effectiveness of the DENVER Protocol
Early remediation of the communicative and social difficulties of children with autism spectrum disorders (ASD) is central. However, from the age of 6-8 months, children with ASD show a lack of attention to social stimuli such as…
- Trial name
- FACECOM (NCT06253793)
- Where
- 3 sites in France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Depression - Major Depressive Disorder, Bipolar
Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health Trajectories
Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health (BLOOM) is a project that aims to overcome age and diagnostic boundaries to generate person-specific longitudinal profiles of mental…
- Conditions
- Depression - Major Depressive Disorder, Bipolar, Psychosis, Eating Disorder NOS
- Trial name
- BLOOM (NCT06978452)
- Where
- Canada
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Autism Sibling
Sibwatch: Optimizing Intervention Options for Infants and Toddler Siblings of Autistic Children
This rigorous randomized controlled trial will evaluate the efficacy and acceptability of a preemptive, telehealth intervention (tele-ImPACT) in a large, representative sample of infant siblings of autistic children, who are…
- Trial name
- Sibwatch (NCT07069413)
- Testing
- tele-ImPACT
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- University of Texas at Austin
Developmental Language Disorder, Language Impairment
Emergent Bilinguals: Child Language Proficiency and Language of Treatment
Of the 12 million children in the USA growing up bilingual, about 1 million experience Developmental Language Disorder (DLD), a disorder in language learning and use.
- Trial name
- NCT06866223
- Testing
- Sentence recast
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Houston
Enhancing Early Language and Cognitive Development in Toddlers Through a Culturally Adapted Home-based Parent Intervention
Home-Based Language and Cognitive Intervention for Arab Toddlers in Israel
This study evaluates the effectiveness of a culturally adapted, home-based program designed to improve language and cognitive development in Arab toddlers in Israel.
- Trial name
- CAHBI-T (NCT07233525)
- Testing
- Culturally Adapted Parent-Implemented Intervention, Child Health Education Sessions
- Where
- Israel
- Volunteers
- 240 people
- Sponsor
- Hillel Yaffe Medical Center
Autism Spectrum Disorder
Peer Interventions for Preschoolers With Autism
This proposal will evaluate a series of peer-mediated interventions (PMIs) for preschool children (3 to 6 years) with ASD and limited or no spoken language, using an innovative Sequential Multiple Assignment Randomized Trial…
- Trial name
- PIPA (NCT05799599)
- Testing
- Stay-Play-Talk Basic, Stay-Play-Talk Plus, Stay-Play-Talk Advanced
- Where
- 2 sites in United States
- Volunteers
- 132 people
- Sponsor
- University of Kansas
Developmental Dyslexia, Reading Problem
Personalization of Visual Characters and Text-to-Speech (TTS) to Support Learning in Students With Reading Difficulties
Previous research has shown the importance of font type, size and spacing to facilitate text reading in dyslexia. A special automatized procedure was designed to select the most favorable parameters for both text visualization…
- Trial name
- NCT06947512
- Testing
- Seleggo Test
- Where
- 3 sites in Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Developmental Dyslexia
Immediate Effects of Active Prisms on Reading Automaticity and Motor Control in Young Adults With Developmental Dyslexia
Developmental dyslexia is associated with persistent difficulties in reading automaticity. AUTO-DYS investigates whether a single, brief intervention using active prisms changes the complexity of nonlinear movement dynamics and…
- Trial name
- AUTO-DYS (NCT07868367)
- Testing
- Individually Selected Active Prisms.
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Lille University
Neurological Impairments, Genetic Syndrome
Speech Therapy and Parenting for Early Socio-communicAtive sKills
Every year, millions of children are diagnosed with neurodevelopmental disabilities. This term covers a wide range of conditions, from genetic syndromes to brain injuries such as cerebral palsy.
- Conditions
- Neurological Impairments, Genetic Syndrome, Neurodevelopmental Disability, Developmental Delays
- Trial name
- SPEAK (NCT06666777)
- Testing
- Intervention focused on intersubjective prelinguistic and socio-communicative skills, Standard speech therapy intervention
- Where
- 9 sites in Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Eugenio Medea
Autism Spectrum Disorder, Autism Spectrum Disorder (ASD)
Intranasal Insulin for Autism Spectrum Disorder in Children and Young Adults Aged 4 to 21 Years
This observational study evaluates the real-world use of intranasal insulin in children and young adults with autism spectrum disorder (ASD) utilizing the ViaNase™ device developed by Kurve Therapeutics.
- Conditions
- Autism Spectrum Disorder, Autism Spectrum Disorder (ASD), Autism Spectrum Disorder High-Functioning, Autism Spectrum Disorder With Absence of Functional Language
- Trial name
- IN-INS-AUT (NCT07521371)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Healing Hope International
MONITOR, COACH
Promoting Early Intervention Timing and Attention to Language
The proposed study (PETAL: Promoting Early intervention Timing and Attention to Language) aims to determine the timing of intervention among infants with Increased Likelihood for Autism (ILA; at risk for autism by virtue of…
- Trial name
- PETAL (NCT05853861)
- Testing
- JASPER Babble
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- University of California, Los Angeles
Autism, ADHD
Spanish-language Executive Function Intervention for Children With Autism and/or ADHD
The goal of this clinical trial is to learn whether the Spanish-language version of Unstuck and On Target (SL-Unstuck), an executive functioning (EF) intervention, is feasible, acceptable, and effective for Spanish-speaking…
- Trial name
- NCT07084324
- Testing
- Unstuck and On Target
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Colorado, Denver
Dyslexia, Developmental, Reading
Enhancing Letter-Speech Sound Learning and Reading Network Activation With Transcranial Electrical Stimulation
This study investigates the effects of transcranial electrical stimulation (tES) on the brain and its potential to enhance reading-related learning.
- Conditions
- Dyslexia, Developmental, Reading, Dyslexia, Learning
- Trial name
- LexiStim (NCT07546292)
- Testing
- Transcranial random noise stimulation
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Silvia Brem
Language Delay, Substance Use Disorders
Prevent Language Delays and Disorders Among Children of Caregivers With Substance Use Disorders With Community Groups and Individualized Services
The goal of this clinical trial is to test ways to improve early language development among young children of parents with substance use disorder (SUD).
- Conditions
- Language Delay, Substance Use Disorders, Language Disorders in Children, Language Development
- Trial name
- NCT07529327
- Testing
- Comilia Group, Interaction Review Enhancement, Practical Support Enhancement
- Where
- United States
- Volunteers
- 244 people
- Sponsor
- University of Oregon