Clinical trials: Developmental Psychological Disorder
Autism, Pediatric Autism
Open-label Study of Safety and Tolerability of Memantine in Children With Autism
The purpose of this study is to evaluate the long-term safety and tolerability of memantine in the treatment of autism in pediatric patients.
- Trial name
- NCT01999894
- Testing
- Memantine HCl
- Where
- 19 sites in United States
- Volunteers
- 102 people
- Sponsor
- Forest Laboratories
Mental Retardation, Developmental Delay
Biomarker for Sanfilippo Type A-B-C-D Disease (BioSanfilippo)
Development of a new MS-based biomarker for the ear-ly and sensitive diagnosis of Sanfilippo Disease Type A-B-C-D from blood (plasma)
- Trial name
- BioSanfilippo (NCT02298686)
- Where
- 5 sites in Egypt, Germany and 2 more
- Sponsor
- CENTOGENE GmbH Rostock
GAINS Expert Guiding Technology to Coach Life Skill Teaching
GAINS Expert Guiding Technology to Coach Life Skill Teaching
Based on proven techniques in operant conditioning, the expert behavior guiding functionality in GAINS to teach life skills will be evaluated.
- Trial name
- NCT07203105
- Testing
- GAINS expert guiding technology to coach life skill teaching
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Guiding Technologies Corporation
Autism
Testing Conversational Agents as a Digital Companion
There is a need and opportunity to improve the supports, transitions, and life outcomes of people with autism spectrum disorder.
- Trial name
- NCT07533331
- Testing
- self-directed goal coaching
- Where
- 3 sites in United States
- Volunteers
- 38 people
- Sponsor
- Friendi.fi Corporation
Anterior Ischemic Optic Neuropathy
PDE5 Inhibitor Use and Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)
The primary objective of this study is to determine whether the use of PDE5 inhibitors (vardenafil, sildenafil, or tadalafil) increases the risk for the development of NAION.
- Trial name
- NCT00867815
- Testing
- Diagnostic procedures
- Where
- 13 sites in United States, Australia and 1 more
- Volunteers
- 10 people
- Sponsor
- Bayer
Irritability Associated With Autism Spectrum Disorder
A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With Autism Spectrum Disorder
The purpose of this study is to assess KarXT + KarX-EC for the treatment of irritability associated with autism in children and adolescents.
- Trial name
- NCT07285798
- Testing
- KarXT, KarX-EC
- Where
- 67 sites in United States, France and 8 more
- Volunteers
- 176 people
- Sponsor
- Bristol-Myers Squibb
Autism Spectrum Disorder
A Study to Investigate the Pharmacokinetics, Safety, and Tolerability of Balovaptan in Children With Autism Spectrum Disorder
This was a Phase Ib, multicenter, open-label study in children 2-4 years old with autism spectrum disorder (ASD) to investigate the pharmacokinetics, safety, and tolerability of an oral dose of balovaptan once a day (QD).
- Trial name
- NCT04049578
- Testing
- Balovaptan
- Where
- 5 sites in United States
- Volunteers
- 2 people
- Sponsor
- Hoffmann-La Roche
Autism
SynapDx Autism Gene Expression Analysis Study (STORY)
This study will prospectively enroll approximately 880 children, at least 18 months and less than 60 months of age, who have been referred to a pediatric developmental evaluation center.
- Trial name
- STORY (NCT01810341)
- Where
- 20 sites in United States, Canada
- Volunteers
- 880 people
- Sponsor
- SynapDx
Work Related Stress
Validation of an Employee Remote Workplace Stress Measure Embedded Within a Novel Employee Wellbeing App
This study aims to validate an adapted workplace stress scale (American Institute of Stress) for employees working remotely during the COVID-19 pandemic.
- Trial name
- NCT04752683
- Testing
- MyBuddy Employee Wellbeing App
- Volunteers
- 220 people
- Sponsor
- Holly Risdon
Autism Spectrum Disorder
Safety and Tolerability of Cannabidivarin (CBDV) in Children and Young Adults With Autism Spectrum Disorder
To determine the safety and tolerability of GWP42006 (cannabidivarin, CBDV) in children and young adults with autism spectrum disorder (ASD) and to examine the effect of GWP42006 on communication, social interactions, sleep…
- Trial name
- NCT03849456
- Testing
- GWP42006
- Where
- 3 sites in United States
- Volunteers
- 1 people
- Sponsor
- Jazz Pharmaceuticals
Pregnancy Related, Sleep
Sleep in Late Pregnancy - Artificial Intelligence Development for the Detection of Disturbances and Disorders
SLeeP AID4 is a single-group, single-arm, Canada-wide, non-randomised, unblinded, in-home, observational study to prospectively collect and build a data set of natural sleep behaviour and physiology in maternal-fetal dyads (and…
- Conditions
- Pregnancy Related, Sleep, Sleep-Disordered Breathing, Sleep Disturbance
- Trial name
- SLeeP AID4 (NCT05376475)
- Testing
- Infrared video-audio camera, Level III home sleep apnea test, Maternal-fetal transabdominal electrocardiographic heart rate monitor
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shiphrah Biomedical Inc.
Autism
Post-Marketing Surveillance Study of Aripiprazole in Patients With Autism
The purpose of this study is to evaluate the safety and effectiveness of aripiprazole in patients with autism in the real world clinical setting in Japan.
- Trial name
- NCT03179787
- Testing
- Aripiprazole oral product
- Where
- Japan
- Volunteers
- 528 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Healthy, CVA
Development of Automated Analysis to Electroencephelogram (EEG) Data in Patients Treated at the Sagol Hyperbaric Medicine and Research Center at the Years 2017-2019.
DELPhI software developed for the analysis of EEG recordings in response to magnetic stimulation in relation to clinical data.
- Conditions
- Healthy, CVA, Hemorrhage, TBI (Traumatic Brain Injury)
- Trial name
- NCT04095377
- Testing
- No intervention, this is a retrospective study.
- Where
- Israel
- Volunteers
- 875 people, healthy volunteers welcome
- Sponsor
- QuantalX Neuroscience
Autism Spectrum Disorder
Early, Objective Detection of Autism.
1- To test the hypothesis that using the SensoDetect Brainstem Evoked Response Audiometry (BERA) technology may be an effective support tool for pediatricians to detect autism.
- Trial name
- NCT06447285
- Testing
- SensoDetect BERA technology
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- SensoDetect
Alcohol Impairment, Nystagmus
Alcohol Impairment Detection in Healthy Adult Users With the Gaize Device
This study evaluates the effectiveness of the Gaize virtual reality headset as a non-invasive tool for detecting alcohol-related impairment through ophthalmic and neurological indicators.
- Conditions
- Alcohol Impairment, Nystagmus, Virtual Reality, Lack of Smooth Pursuit
- Trial name
- AAI (NCT07126938)
- Testing
- Alcoholic beverage
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gaize
Asperger Syndrome, High Functioning Autism
Portable Visual Guidance System Phase II
Abstract: In Phase I, we designed and tested a Portable Visual Guidance System (PVGS), which combines a PDA - for user guidance - and an Internet website - for linking the user to an educational support team.
- Trial name
- PVGS-II (NCT00848874)
- Testing
- PVGS
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Minna Levine, PhD
Autistic Disorder
A Study of RO5028442 in Adult Male High-Functioning Autistic Patients
This multi-center, randomized, double-blind study will evaluate exploratory biomarkers and the safety and tolerability of a single dose of RO5028442 in adult male high-functioning autistic patients.
- Trial name
- NCT01474278
- Testing
- RO5028442
- Where
- 3 sites in United States
- Volunteers
- 19 people
- Sponsor
- Hoffmann-La Roche
Learning Disabilities, Child
Development, Validation and Testing of an Education Program for Identification of Learning Disabilities Among School Children by Primary School Teachers in Qatar
Aim The aim of this study to develop, validate and test an education program for identification of learning disabilities among school children by Primary school teachers in Qatar Objectives 1.
- Trial name
- LD - Learning (NCT06642974)
- Testing
- Education module on learning disabilities, pamphlet on learning disability
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Autism Spectrum Disorder
Study of Application of Transcutaneous Trigeminal Nerve Stimulation on Autism Spectrum Disorder
This study aims to evaluate the safety and the efficacy of applying transcutaneous trigeminal nerve stimulator (NuEyne P01) on autism spectrum disorder.
- Trial name
- NCT06233279
- Testing
- Charge-Balanced, Symmetric Nerve Stimulation
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Nu Eyne Co., Ltd.
Autism Spectrum Disorder
Non-invasive Auricular Fiber Vagus Nerve Stimulation (afVNS) for Treatment of Autism Spectrum Disorder
Non-invasive vagus nerve stimulation for the symptomatic improvements in Autism Spectrum Disorder
- Trial name
- NCT06473623
- Testing
- vagus nerve stimulation
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- Neuropix