Clinical trials: Developmental Trauma Disorder
Hospitalism in Children, Post Traumatic Stress Disorder
Pilot Testing of an Equity Focused and Trauma-informed Communication Intervention During Family-centered Rounds
Development and pilot testing of a clinician coaching communication intervention to improve communication between medical teams and caregivers (parents, family members) of children in the hospital.
- Trial name
- EFTI (NCT05618652)
- Testing
- Equity Focused and Trauma-Informed Communication Intervention
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Duke University
Epilepsy, Dravet Syndrome
A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-935 (OV935) as an Adjunctive Therapy in Pediatric Participants With Developmental and/or Epileptic Encephalopathies
The purpose of this study is to investigate the effect on the frequency of all seizures (convulsive and drop) in participants treated with TAK-935 compared to placebo.
- Conditions
- Epilepsy, Dravet Syndrome, Lennox-Gastaut Syndrome
- Trial name
- ELEKTRA (NCT03650452)
- Testing
- TAK-935
- Where
- 44 sites in United States, Australia and 6 more
- Volunteers
- 141 people
- Sponsor
- Takeda
Spinal Cord Injury
Development of an Ergonomic Wheelchair Pushrim
The purpose of this study is to test the effectiveness of newly designed ergonomic manual wheelchair handrims called the Natural-Fit and PalmRim when compared to a new standard handrim.
- Trial name
- NCT00392860
- Testing
- Natural-Fit, PalmRim, Handrim Control Group
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- VA Pittsburgh Healthcare System
Posttraumatic Stress Disorder, Sexual Assault
RCT for Innovating Stress-related eHealth
The Randomized Control Trial for Innovating Stress-related eHealth (RISE) Study tests the hypotheses that a highly promising digital therapeutic (RISE Guide) targeting anxiety sensitivity (AS) will be acceptable to women sexual…
- Conditions
- Posttraumatic Stress Disorder, Sexual Assault, Pain
- Trial name
- RISE (NCT05305235)
- Testing
- RISE Guide, Relaxation Control
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Pressure Ulcer, Pressure Injury
Development of Technologies to Increase In-Seat Movement to Prevent Sitting-Acquired Pressure Injuries in Wheelchair Users
Pressure-related injuries in individuals with SCI and persons who use wheelchairs are one of the most dangerous secondary health problems encountered throughout the lifespan.
- Conditions
- Pressure Ulcer, Pressure Injury, Wheelchair
- Trial name
- NCT04934137
- Testing
- Sensoria, AW-Shift
- Where
- 4 sites in United States
- Volunteers
- 46 people
- Sponsor
- Mayo Clinic
Posttraumatic Stress Disorder, Tonic Immobility Response
Development and Evaluation of a Tonic Immobility Focused Psychoeducational Intervention
A randomized controlled trial is planned to evaluate a brief, web-based intervention intended to educate about tonic immobility (TI) within a sample of those who experienced TI in the context of a traumatic event.
- Trial name
- TIP (NCT05113277)
- Testing
- Tonic Immobility Psychoeducation (TIP), Health Education Training (HET)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Florida State University
Spinal Cord Injury
Development of Low Cost Devices to Increase Access to Treadmill Training
The goals of this Model System Program are to expand upon and advance the findings and outcomes of previous and current Model Systems clinical research, to continue to develop and study the effectiveness of innovative treatment…
- Trial name
- NCT02560506
- Testing
- Elastic assisted treadmill walking
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Shirley Ryan AbilityLab
Central Auditory Processing Disorder, Traumatic Brain Injury
Central Auditory Processing Disorders Associated With Blast Exposure
The incidence of central auditory dysfunction in war fighters who are exposed to high-explosive blasts while serving in combat have not been clearly determined.
- Conditions
- Central Auditory Processing Disorder, Traumatic Brain Injury, Hearing Loss
- Trial name
- NCT00554801
- Testing
- Audiological testing
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Depression, Anxiety, Stress
A Trauma-Informed Intervention for Positive Youth Development and Teacher Wellness in Rural Montana
"A Trauma-Informed Intervention for Positive Youth Development and Teacher Wellness in Rural Montana" is intended to help mitigate stressors that may contribute to poor behavioral and mental health in rural Montana teachers.
- Trial name
- NCT05085392
- Testing
- Trauma-Informed Yoga
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Montana State University
Quadriplegia, Spinal Cord Injury
Evaluation of a Tongue Operated Assistive Technology for Individuals With Severe Paralysis
This study was intended to evaluate a new assistive neuro-technology, known as the Tongue Drive System (TDS), by its potential end-users, i.e.
- Conditions
- Quadriplegia, Spinal Cord Injury, ALS
- Trial name
- TDS-1 (NCT01124292)
- Testing
- Tongue Piercing, Usability assessment
- Where
- 4 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Hemianopia, Hemianopsia
Collision Warning Device for Blind and Visually Impaired
This study evaluates a novel collision warning device to help people with severe vision impairment or blindness avoid collisions with obstacles.
- Conditions
- Hemianopia, Hemianopsia, Peripheral Visual Field Defect, Blindness
- Trial name
- NCT03057496
- Testing
- Collision warning device
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Suicide, Firearm Injury
Emergency Room Firearm and Medication Safety Intervention
Seventeen United States Veterans die by suicide each day. Nearly three-fourths of those Veterans die from firearm injury or poisoning, and many seek care in VA Emergency Departments (ED) prior to suicide attempts.
- Conditions
- Suicide, Firearm Injury, Overdose
- Trial name
- NCT04797221
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- VA Office of Research and Development
Respiratory Distress Syndrome, Adult, Sepsis
Early Insulin and Development of ARDS
Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) is a severe lung condition that causes respiratory failure. Symptoms usually develop within 24 to 48 hours of an original injury or illness, and people with…
- Conditions
- Respiratory Distress Syndrome, Adult, Sepsis, Hyperglycemia
- Trial name
- NCT00605696
- Testing
- Insulin
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Albert Einstein College of Medicine
Dysplasia; Hip
Biomechanical Reconstruction of Three Different Hip Stem Designs in Hip Dysplasia Using a 3D CT-based Planning Software
A random population of 200 CT scans of pelvis and thigh in an adult population affected by hip dysplasia will be selected. The aim of this study is to evaluate the biomechanical reconstruction of the hip anatomy provided by three…
- Trial name
- CTdevice (NCT04904640)
- Testing
- Hip stem
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Istituto Ortopedico Rizzoli
Autism, Trauma
A Pilot Participatory Program Evaluation of a Virtual Trauma Support Program for Autistic Adults
The goal of this single-group clinical trial is to learn about the initial efficacy and feasibility of telehealth-delivered Written Exposure Therapy (WET) for autistic adults with traumatic stress symptoms.
- Conditions
- Autism, Trauma, Posttraumatic Stress Disorder, Posttraumatic Stress Symptom
- Trial name
- NCT05862467
- Testing
- Written Exposure Therapy (WET) via telehealth
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Wyoming
Traumatic Brain Injury
Pilot and Feasibility of MEMI for Chronic Traumatic Brain Injury
This is a pilot and feasibility study for a mobile phone-delivered intervention for memory, called MEMI (memory ecological momentary intervention), that was designed to support adults with chronic traumatic brain injury with…
- Trial name
- NCT06375421
- Testing
- MEMI (Memory Ecological Momentary Intervention) Spaced Retrieval, Blocked Retrieval
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Pain, Acute, Pain, Chronic
Development and Validation of a Digital Pain-Reduction Kit for Musculoskeletal Injuries
This study will test the effectiveness of an evidence-based, multi-modal, "digital pain-reduction kit" as a non-pharmacological supplement to managing patients with pain due to musculoskeletal injuries.
- Trial name
- NCT03187132
- Testing
- Digital Pain Reduction Kit, Active Control
- Where
- United States
- Volunteers
- 245 people
- Sponsor
- Cedars-Sinai Medical Center