Clinical trials: Dexamethasone Administration
Laryngotracheobronchitis, Croup
Efficacy Of Oral Dexamethasone Versus Parenteral Dexamethasone In The Management Of Mild To Moderate Croup
Croup (laryngotracheobronchitis) is a viral infection of the upper airway that causes throat swelling, leading to a barking cough, stridor, and hoarseness.
- Trial name
- NCT06959407
- Testing
- oral dexamethasone, intramuscular dexamethasone
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Arooj Khan
Symptomatic Irreversible Pulpitis
Preoperative Dexamethasone Injection to Improve Local Anesthesia Success in Endodontic Treatment
This study aims to determine whether giving a single dose of 4mg dexamethasone before root canal treatment can reduce the amount of pain patients experience during the procedure .
- Trial name
- DILAS (NCT07699315)
- Testing
- dexamethasone, Saline (0.9% NaCl)
- Volunteers
- 60 people
- Sponsor
- Watim Medical & Dental College
Asthma
Trial of One Versus Two Doses of Dexamethasone for Pediatric Asthma Exacerbation
Comparing one versus two doses of oral dexamethasone for the treatment of asthma in the pediatric emergency department.
- Trial name
- R2D2 (NCT02725008)
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Geoffrey W Jara-Almonte
Multiple Myeloma, Extramedullary Plasmacytoma
Daratumumab Combined With Bortezomib, Cyclophosphamide and Dexamethasone for the Treatment of Multiple Myeloma Patients Presenting With Extramedullary Disease
This trial will try to establish the feasibility and efficacy of the combination of DaraVCD in Multiple Myeloma (MM) patients presenting with extramedullary disease (EMD). The study will be conducted as a Phase II trial.
- Trial name
- EMN19 (NCT04166565)
- Testing
- Daratumumab, Bortezomib, Cyclophosphamide
- Where
- 8 sites in Greece, Italy and 1 more
- Volunteers
- 41 people
- Sponsor
- Stichting European Myeloma Network
Scoliosis Idiopathic, Scoliosis; Adolescence
Dexamethasone Vs. Dexmedetomidine for ESPB in Pain Management After Pediatric Idiopathic Scoliosis Surgery
Effect of perineurial dexamethasone and dexmedetomidine on erector spinal plane block duration for pediatric, idiopathic scoliosis surgery.
- Trial name
- NCT06086431
- Testing
- 0.9% sodium chloride, Dexamethasone, Dexmedetomidine
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Extranodal NK/T-cell Lymphoma, Nasal Type
MESA Versus ESA in the Treatment of Early Stage NK/T-cell Lymphoma
Extranodal natural killer (NK)/T-cell lymphoma (ENKTL), nasal type, is a distinct and heterogeneous histopathologic subtype of non-Hodgkin lymphoma (NHL), accounting for 5%~10%.
- Trial name
- NCT02631239
- Testing
- Methotrexate, Etoposide, Dexamethasone
- Where
- China
- Volunteers
- 256 people
- Sponsor
- Ruijin Hospital
Multiple Myeloma
Fludarabine Added to Induction Treatment in Untreated Multiple Myeloma Patients
Multiple myeloma is an incurable malignant disease which evnetuelly will relapse after primary treatment. Clonal B-cells have been identified and in theory these cells might be sleeping during primary treatment and be responsible…
- Trial name
- NCT00382694
- Testing
- Fludarabine
- Where
- 6 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- Nordic Myeloma Study Group
COVID-19
Treatments for COVID-19: Canadian Arm of the SOLIDARITY Trial
This study is an adaptive, randomized, open-label, controlled clinical trial, in collaboration with countries around the world through the World Health Organization.
- Trial name
- CATCO (NCT04330690)
- Testing
- Artesunate, Imatinib, Infliximab
- Where
- 53 sites in Canada
- Volunteers
- 2,900 people
- Sponsor
- Sunnybrook Health Sciences Centre
Analgesia, Postoperative Pain
Multimodal Analgesic Treatment Versus Traditional Morphine Analgesia After Cardiac Surgery
To test if multimodal analgesia with different analgesic medication offer better pain relief, lesser side effects and is safe compared to conventionel opiod analgesia after cardiac surgery.
- Trial name
- NCT01966172
- Testing
- Ibuprofen, Gabapentin, Morphine
- Where
- Denmark
- Volunteers
- 180 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Refractory Plasma Cell Myeloma
Dexamethasone, Elotuzumab, and Pomalidomide in Treating Patients With Refractory Multiple Myeloma
This phase II trial studies how well dexamethasone, elotuzumab, pomalidomide work in treating patients with multiple myeloma that has not responded to previous treatment.
- Trial name
- NCT03713294
- Testing
- Dexamethasone, Elotuzumab, Pomalidomide
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Mayo Clinic
MS Patient With Relpasing Remitting Attacks
Nasal Administration of Dexamethasone for Multiple Sclerosis (MS) Treatment
The study aims to assess the safety and efficacy of nasale administration of Dexamethasone in relapsing MS patients
- Trial name
- NCT00674141
- Testing
- Dexamethasone soduim phosphate
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Hadassah Medical Organization
Local Anesthetic, Ultrasound
TAP Block With Methyl-prednisolone as a Pain Treatment Modality After Total Abdominal Hysterectomy Procedures
The aim of this work to compare between the efficacy of ultrasound guided TAP block with dexamethasone as an adjuvant versus ultrasound guided TAPB with methyl prednisolone as an adjuvant to local anesthetic for postoperative…
- Conditions
- Local Anesthetic, Ultrasound, Pain, Acute
- Trial name
- NCT06131593
- Testing
- TAPB with dexamethasone as an adjuvant to local anesthetics, TAPB with methylprednisolone as an adjuvant to local anesthetics
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kasr El Aini Hospital
Irreversible Pulpitis
Oral Dexamethasone for the Management of Symptomatic Irreversible Pulpitis Without Performing Pulpotomy
The efficacy of short course orally administered dexamethasone on the reduction of pain before conventional pulpotomy has not yet been demonstrated.
- Trial name
- NCT05761730
- Testing
- Dexamethasone Oral
- Where
- Lebanon
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- May Samaha
Inflammation, Perioperative Morbidity
The Effects of Corticosteroids, Glucose Control, and Depth-of-Anesthesia on Perioperative Inflammation and Morbidity From Major Non-cardiac Surgery (Dexamethasone, Light Anesthesia and Tight Glucose Control (DeLiT Trial))
Evidence thus suggests that steroid administration, tight glucose control, and avoidance of deep anesthesia may decrease perioperative morbidity by reducing the inflammatory response to surgery.
- Trial name
- NCT00995501
- Testing
- Dexamethasone Sodium Sulfate, Insulin, anesthesia management
- Where
- United States
- Volunteers
- 381 people
- Sponsor
- d sessler
Cataract
A Study to Evaluate the Efficacy and Safety of DEXYCU® for the Treatment of Ocular Pain Associated With Cataract Surgery (2)
A Phase 3, Prospective, Randomized, Double-masked, Placebo-controlled, Parallel-design, Multicenter Study to Evaluate the Efficacy and Safety of DEXYCU® for the Treatment of Ocular Pain Associated with Cataract Surgery
- Trial name
- NCT05550363
- Testing
- Dexycu
- Sponsor
- EyePoint Pharmaceuticals, Inc.
Post-Mastectomy Chronic Pain Syndrome
Dex & Mastectomy Pain
Chronic post-surgical pain is a common complication following mastectomy and represents a significant source of long-term morbidity.
- Trial name
- NCT07556952
- Testing
- Dexamethasone (intravenous), Normal Saline (0.9% NaCl)
- Where
- Canada
- Volunteers
- 170 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Distal Radius Fracture
Randomized Controlled Trial Assessing the Effect of Dexamethasone on Postoperative Function After Distal Radius Fixation
The study is designed to assess the use of intraoperative dexamethasone on postoperative analgesia and stiffness after open reduction and internal fixation of distal radius fractures.
- Trial name
- NCT04889547
- Testing
- Dexamethasone, No dexamethasone
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Viral Conjunctivitis
A Trial of Topical Dexamethasone Versus Artificial Tears for Treatment of Viral Conjunctivitis
Viral conjunctivitis causes redness, tearing, swelling, and irritation of the eyes that typically lasts from 1 to 3 weeks. Current management of this condition focuses on supportive care while the viral infection completes its…
- Trial name
- NCT01481519
- Testing
- dexamethasone 0.1%/povidone-iodine 0.4%, Artificial Tears
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- University of Campinas, Brazil
Multiple Myeloma, First Relapse
Dara-PD in the Treatment of Patients With First Relapse of Multiple Myeloma
At present, there is no prospective study on the treatment of first-relapsed multiple myeloma with daratumumab plus pomalidomide and dexamethasone (Dara-Pd).
- Trial name
- NCT06252792
- Where
- China
- Volunteers
- 50 people
- Sponsor
- FengYan Jin
Multiple Myeloma
Combined Carfilzomib and Hydroxychloroquine in Patients With Relapsed/Refractory Multiple Myeloma
Multiple myeloma (MM) is a neoplastic expansion of bone marrow plasma cells. Despite advances in treatment in recent years, MM is still a fatal disease.
- Trial name
- MYELOMA-HCQ (NCT04163107)
- Testing
- Hydroxychloroquine, Carfilzomib Injection, Dexamethasone
- Where
- 2 sites in Norway
- Volunteers
- 19 people
- Sponsor
- Norwegian University of Science and Technology