Clinical trials: Dexamethasone Administration
Multiple Myeloma
A Study to Learn How Safe and How Well Linvoseltamab Works Compared to Standard Treatment in Adult Patients With Multiple Myeloma Who Are Not Eligible for Transplant
This study is researching an experimental drug called linvoseltamab. The study is focused on participants with newly diagnosed multiple myeloma (NDMM) who are ineligible for autologous stem cell transplantation…
- Trial name
- NCT06932562
- Testing
- Linvoseltamab, Daratumumab, Lenalidomide
- Where
- 59 sites in Australia, Austria and 16 more
- Volunteers
- 1,000 people
- Sponsor
- European Myeloma Network B.V.
Scoliosis, Scoliosis Idiopathic
Dexamethasone for ESPB in Pain Management After Pediatric Idiopathic Scoliosis Surgery
Effect of perineurial dexamethasone on erector spinal plane block duration for pediatric, idiopathic scoliosis surgery.
- Conditions
- Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence
- Trial name
- NCT06616220
- Testing
- Dexamethasone, 0.9%NaCl
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Multiple Myeloma
Phase 2 Trial of Chidamide-Lenalidomide-Dexamethasone(CRD) Regimen in R/R MM
The purpose of this study is to evaluate the safety and effectiveness of combination of Chidamide-Lenalidomine-Dexamethasone in relapsed or refractory multiple myeloma patients
- Trial name
- NCT03605056
- Testing
- chidamide, lenalidomide, dexamethasone
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Peng Liu
Graves' Disease
Prevention Relapse of Graves' Disease by Intrathyroid Injection of Dexamethasone
Antithyroid drugs are widely used in treatment of Graves' disease (GD), but after therapy withdrawal, relapse rate is very high.
- Trial name
- NCT00917241
- Testing
- MMI combined with IID, MMI
- Volunteers
- 218 people
- Sponsor
- Xiao-Ming Mao
Nonneoplastic Condition
Prednisone or Dexamethasone in Newly Diagnosed, Previously Untreated Primary Immune Thrombocytopenic Purpura
RATIONALE: Drugs, such as prednisone and dexamethasone, may change the immune system and be an effective treatment for primary immune thrombocytopenic purpura.
- Trial name
- ITP0207 (NCT00657410)
- Testing
- dexamethasone, prednisone, quality-of-life assessment
- Where
- 42 sites in Italy
- Volunteers
- 150 people
- Sponsor
- Gruppo Italiano Malattie EMatologiche dell'Adulto
Myeloma
A Study of the Bortezomib, Lenalidomide, and Dexamethasone Regimen for the Treatment of Newly Diagnosed Multiple Myeloma Patients
A real-world prospective registry study for patients with newly diagnosed multiple myeloma (NDMM) has been conducted at the First Affiliated Hospital of Soochow University since August 2018.
- Trial name
- NCT07206810
- Testing
- Bortezomib, Lenalidomide, and Dexamethasone
- Where
- China
- Volunteers
- 419 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Emesis
Comparison of Olanzapine and Metoclopramide For Treatment Of bReakThrough Emesis
This trial is designed to evaluate olanzapine compared to the metoclopramide in the treatment of break through emesis after prophylaxis with dexamethasone, 5-HT 3 receptor antagonists and aprepitant in patients receiving…
- Trial name
- COMFORT (NCT01148264)
- Testing
- olanzapine, metoclopramide
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- Karin Jordan
Blepharokeratoconjunctivitis
Zylet vs TobraDex in Blepharokeratoconjunctivitis
The objective of this study is to evaluate the safety and efficacy of Zylet vs. Tobradex in the treatment of ocular inflammation associated with blepharokeratoconjunctivitis
- Trial name
- NCT00447577
- Testing
- Loteprednol etabonate and tobramycin ophthalmic suspension, Tobramycin and dexamethasone ophthalmic suspension
- Where
- United States
- Volunteers
- 276 people
- Sponsor
- Bausch & Lomb Incorporated
INFERTILITY
Analgesic Efficacy of Dexamethasone in Different Routes of Administration in Transverse Abdominis Plane Block
Transverse abdominis plane (TAP) block is a regional anaesthesia technique that provides analgesia to the parietal peritoneum as well as skin and muscles of the anterior abdominal wall.
- Trial name
- AEDDATB (NCT02838719)
- Testing
- Perineural Dexamethasone acetate, Intravenous dexamethasone acetate
- Volunteers
- 40 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Multiple Myeloma
Managed Access Program for Combination Treatment With Belantamab Mafodotin in Multiple Myeloma
Compassionate use access to belantamab mafodotin (GSK2857916) (in combination with bortezomib/dexamethasone or pomalidomide/dexamethasone) for eligible participants with multiple myeloma previously treated with at least 1 prior…
- Trial name
- NCT03763370
- Testing
- Belantamab mafodotin 2.5 mg/kg IV Q3Weeks + Vd (BVd), Belantamab mafodotin 2.5/1.9 mg/kg IV Q4Weeks + Pd (BPd)
- Sponsor
- GlaxoSmithKline
Dry Eye
Safety and Efficacy of Dexamethasone Ophthalmic Insert (Dextenza®) in the Management of Clinically Significant Dry Eye
To determine efficacy and safety profile of dexamethasone 0.4mg lacrimal insert in dry eye related ocular surface inflammation.
- Trial name
- NCT04498468
- Testing
- Sustained Release Dexamethasone, 0.4 mg, E-Caprolactone-L-Lactide copolymer (PCL) punctal plug
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Dry Eye
Comparing Treatment of Dry Eye With Intracanalicular Dexamethasone, Restasis, and/or Lotemax
This 6 month study seeks to compare the use of Intracanalicular Dexamethasone in conjunction with Restasis (cyclosporine ophthalmic emulsion) for the treatment of signs and symptoms of dry eye disease as compared to Restasis with…
- Trial name
- NCT04555694
- Testing
- Cyclosporine, Loteprednol Etabonate, Dexamethasone Ophthalmic 0.4 Mg Ophthalmic Insert
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Thomas Chester, OD
Macular Edema
Simultaneous Therapy With Intravitreal Dexamethasone Implant and Bevacizumab for the Treatment of Macular Edema
Retrospective cases series is a non-randomized, open-label, single-center investigation (Retina Clinic, São Paulo, Brazil) of patients diagnosed with macular edema secondary to diabetic retinopathy (DME) and retinal vein…
- Trial name
- NCT02623673
- Testing
- simultaneous treatment with intravitreal injection of bevacizumab 1.25mg and intravitreal implant of dexamethasone 0.7mg.
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Retina Clinic, Sao Paulo, Brazil
Cataract
The SITE Study - Dexamethasone Ophthalmic Insert In OR on Day of Surgery Versus In-office Post-Op Day 1
To assess the safety and effectiveness of treatment with an intracanalicular dexamethasone (0.4mg) insert in the operating room following cataract surgery/intraocular lens implant (IOL) compared to insertion 1-day post-op.
- Trial name
- NCT05143281
- Testing
- Dexamethasone 0.4 MG [Dextenza]
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Grene Vision Group