Clinical trials: Dexamethasone Administration, open to volunteers
Recurrent Plasma Cell Myeloma, Refractory Plasma Cell Myeloma
Leflunomide, Pomalidomide, and Dexamethasone for the Treatment of Relapsed or Refractory Multiple Myeloma
This phase II trial studies how well leflunomide, pomalidomide, and dexamethasone work for the treatment of multiple myeloma that has come back (relapsed) or does not respond to treatment (refractory).
- Trial name
- NCT04508790
- Testing
- Dexamethasone, Leflunomide, Pomalidomide
- Where
- 8 sites in United States
- Volunteers
- 29 people
- Sponsor
- City of Hope Medical Center
Symptomatic Irreversible Pulpitis (SIP), Dental Pain
Local Dexamethasone Administration in Symptomatic Irreversible Pulpitis
Symptomatic irreversible pulpitis is associated with a high incidence of inadequate pulpal anesthesia during endodontic treatment, particularly in mandibular molar teeth.
- Trial name
- SIPDEX (NCT07672873)
- Testing
- Saline (0.9%, sterile, for infusion), Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Marmara University
Light Chain (AL) Amyloidosis
Daratumumab for Patients With Light Chain Amyloidosis
This is a prospective, single-center study exploratory clinical trial, aim to exploring the efficacy and safety of daratumumab in patients with AL amyloidosis, patients were divided into three groups: one group received long-term…
- Trial name
- NCT06376214
- Testing
- Dratumumab / Hyaluronidase Injection [Darzalex Faspro], Pomalidomide 4 MG, autologous stem cell transplantation (ASCT)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Nanjing University School of Medicine
Patient Preference, Patient Outcomes
The PRIME Study: A Randomized, Controlled, Prospective Study
To investigate the outcomes of patients undergoing bilateral RLE surgery with treatment of dexamethasone intracanilicular insert compared to topical standard care steroid.
- Conditions
- Patient Preference, Patient Outcomes, Post-Operative Inflammation, Grade of Post-Operative Cystoid Macular Edema
- Trial name
- NCT04549935
- Testing
- Dextenza, Topical Prednisolone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Vance Thompson Vision - MT
Post Operative Pain Control, Endodontic Treatment
Intracanal Dexamethasone Extrusion and Postoperative Endodontic Pain
The aim of this research is to assess the effect of intentionally extruding a corticosteroid intracanal solution into the periapical tissues on the postoperative pain after root canal treatment in patients with symptomatic…
- Trial name
- NCT06894069
- Testing
- Dexamethasone
- Volunteers
- 80 people
- Sponsor
- University of Jordan
Total Knee Replacement
A Study to Compare Different Ways of Steroid Administration After Total Knee Implantation
We are going to evaluate the difference between perioperative intravenous steroid supplementation, perioperative periarticular steroid supplementation, and standard anaesthesia protocols.
- Trial name
- NCT04432012
- Testing
- Dexamethasone Sodium Phosphate 4 mg/ml intravenous, Dexamethasone Sodium Phosphate 4 mg/ml intra-articular
- Where
- Switzerland
- Volunteers
- 159 people
- Sponsor
- Christian Candrian
Multiple Myeloma
MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)
The purpose of this study is to learn about the study medicine called elranatamab.This study aims to compare elranatamab to other medicines for the treatment of MM (a type of cancer).
- Trial name
- NCT06152575
- Testing
- Elranatamab, Elotuzumab, Pomalidomide
- Where
- 270 sites in United States, Argentina and 25 more
- Volunteers
- 492 people
- Sponsor
- Pfizer
Femoral Neck Fractures
This is a Study to Verify if Periarticular Hip Injection of Corticosteroid After Hip Replacement Reduce the Pain and the Hospitalisation Time
The investigators are going to evaluate if periarticular corticosteroid injection during endoprothesis implantation can lead to any advantage to the patients, namely if it can reduce post-operative pain, lenght and cost of…
- Trial name
- NCT05023369
- Testing
- Dexamethasone is a steroid drug and will be administered as an injectable solution (4mg/ml)
- Where
- Switzerland
- Volunteers
- 110 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Nausea and Vomiting Caused by Chemotherapy
Auricular Point Stimulation Plus Dexamethasone for Nausea and Vomiting Caused by Gemcitabine Plus Paclitaxel
The goal of this clinical trial is to learn if auricular point stimulation plus dexamethasone works to effectively prevent or suppress nausea and vomiting caused by gemcitabine combined with paclitaxel protein-bound in pancreatic…
- Trial name
- ADGP (NCT07537660)
- Testing
- Auricular point stimulation plus dexamethasone
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine