Clinical trials: Dexmedetomidine Analgesia
Pain, Postoperative
Dose Response Study of Dexmedetomidine in Orthopaedic Spine Surgery Patients
To study the multimodal protocol combining adjunct dexmedetomidine with oxycodone in intravenous patient-controlled analgesia bolus dosing and effects in patients scheduled for posterolateral lumbar spine fusion with bilateral…
- Trial name
- DoserespDex (NCT02454881)
- Testing
- Dexmedetomidine, Oxycodone
- Where
- Finland
- Volunteers
- 107 people
- Sponsor
- Turku University Hospital
Hypertension, Resistant, Sympathectomy
Procedural Sedation in Renal Sympathetic Denervation
This retrospective, single-center study investigates the effects of two different sedation regimens-dexmedetomidine versus fentanyl-propofol-on clinical outcomes in patients undergoing catheter-based renal sympathetic denervation…
- Conditions
- Hypertension, Resistant, Sympathectomy, Conscious Sedation, Procedural Sedation and Analgesia
- Trial name
- NCT07293273
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people
- Sponsor
- Ebru Girgin Dinc
Postoperative Pain Management
Dexmedetomidine-Enhanced PCIA After Lobectomy in Nicotine-Dependent Patients
This randomized, double-blind, controlled clinical trial evaluates whether adding dexmedetomidine to an oliceridine-based patient-controlled intravenous analgesia (PCIA) regimen can improve postoperative pain control and…
- Trial name
- DEX-PCIA (NCT07306702)
- Testing
- Oliceridine, Dexmedetomidine
- Where
- China
- Sponsor
- Shenyang Sixth People's Hospital
Postoperative Pain
Efficacy of Dexmedetomidine on Postoperative Analgesia
This prospective, randomized, double-blind study is designed to evaluate the postoperative analgesic efficacy of dexmedetomidine as an adjunct to ropivacaine in erector spinae block in patients undergoing radical mastectomy.
- Trial name
- EDPARMRCT (NCT05110339)
- Testing
- Ropivacaine plus dexmedetomidine, Ropivacaine
- Where
- Mexico
- Volunteers
- 28 people
- Sponsor
- Universidad Autónoma de Tamaulipas
Postoperative Pain, Acute
Effect of Dexmedetomidine Versus Dexamethasone as Adjuvant to Bupivacaine in Ultrasound Guided Erector Spinae Plane Block on Postoperative Analgesia in Myasthenic Patients Undergoing Thoracoscopic Thymectomy
This current comparative study involved 54 patients undergoing thoracoscopic thymectomy who were distributed randomly into three equal groups to receive ultrasound (US)-guided ESPB using 20 ml bupivacaine 0.25% (group B) , 20 ml…
- Trial name
- NCT07424599
- Testing
- Erector Spinae Plane Block
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Sedation and Analgesia
Dexmedetomidine Versus Ketamine Versus Midazolam in Endoscopic Procedures
This study aims to assess the safety and efficacy of dexmedetomidine versus ketamine versus midazolam combined with propofol in cancer patients undergoing gastrointestinal endoscopic procedures.
- Trial name
- NCT04597268
- Testing
- Dexmedetomidine, Ketamine, Midazolam
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- National Cancer Institute, Egypt
Analgesia
Analgesic Protocol With Gabapentin Dexmedetomidine For Postoperative Pain Managment
Assessment of quality of post mastectomy analgesic protocol of Gabapentin and Dexmedetomedine in a placebo-controlled study
- Trial name
- NCT04976374
- Testing
- Dexmedetomidine and Gabapentin, Saline
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute, Egypt
Pharmacological Action
Comparison of Epidural Labor Analgesia With Dexmedetomidine or Sufentanil
The participants: 1800 full-term primiparas will be selected with ASA I-Ⅱgrade, 20 to 35 years old and weighing 55 to 90 kg in the investigator's hospital from may 2018 to December 2018.
- Trial name
- NCT03622047
- Testing
- Dexmedetomidine ropivacaine, No analgesia labor
- Where
- China
- Volunteers
- 1,800 people
- Sponsor
- Fudan University
Elderly, Surgery
Dexmedetomidine Supplemented Analgesia and Incidence of Postoperative Delirium
Delirium is a frequently occurred cerebral complication in elderly patients after surgery, and its occurrence is associated with worse outcomes.
- Conditions
- Elderly, Surgery, Analgesia, Dexmedetomidine
- Trial name
- NCT03012984
- Testing
- Dexmedetomidine supplemented morphine analgesia, Morphine analgesia
- Where
- 12 sites in China
- Volunteers
- 1,500 people
- Sponsor
- Peking University First Hospital
Postoperative Pain, Postoperative Vomiting
Efficacy of Dexmedetomidine for Postoperative Analgesia in Infantile Cataract Surgery
The purpose of the present study was to evaluate the efficacy and safety of subtenon block (SB)anesthesia with dexmedetomidine in combination with bupivacaine versus intravenous dexmedetomidine for postoperative analgesia and…
- Trial name
- NCT02495220
- Testing
- SB dexmedetomidine bupivacaine block, intravenous dexmedetomidine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Postoperative Pain
The Postoperative Analgesic Effect of Combination With Dexmedetomidine in Fentanyl-based Intravenous Patient Controlled Analgesia Compared With Conventional Thoracic Epidural and Intravenous Patient Controlled Analgesia After Radical Open Gastrectomy
The aim of this study to test hypothesis that addition of dexmedetomidine to fentanyl based intravenous patient controlled analgesia (PCA) improves postoperative pain compared with conventional thoracic epidural and intravenous…
- Trial name
- NCT02325882
- Testing
- Dexmedetomidine, Fentanyl 1, Fentanyl 2
- Where
- South Korea
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Pain, Analgesia
Fascia Iliaca Block Versus Intravenous Dexmedetomidine and Ketamine for Positioning Fracture Femur
Proximal femur fractures are one of the commonest fractures especially in the elderly population. Early surgical fixation is the best analgesic for associated pain.
- Trial name
- NCT05705726
- Testing
- ultrasound guided facia iliaca block, Intravenous drug
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Minia University
Pain, Postoperative, Pain, Acute
Opioid-free Anesthesia in Laparoscopic Cholecystectomies
The aim of this study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus fentanyl analgesia in elective laparoscopic…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Cholecystectomy
- Trial name
- NCT05089526
- Testing
- ketamine-lidocaine-dexmedetomidine, fentanyl
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- Aretaieion University Hospital
Analgesia
Intraperitoneal Analgesia in Pediatric Laparoscopy
It is important to keep children undergoing laparoscopic surgery pain free with rapid return to normal activity.
- Trial name
- NCT02820610
- Testing
- Dexmedetomidine, Magnesium Sulfate, Normal saline 0.9 %
- Where
- Egypt
- Volunteers
- 97 people
- Sponsor
- Assiut University
Post-operative Pain
Dexmedetomidine Added to Bupivacaine for ESP Block in Children Undergoing Lower Abdominal Surgeries
This study aims to evaluate the effect of adding dexmedetomidine to bupivacaine in erector spinae plane (ESP) blocks on the duration of postoperative analgesia in pediatric patients undergoing lower abdominal surgery.
- Trial name
- NCT07023991
- Testing
- Bupivacaine, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University