Clinical trials: Dexmedetomidine Infusion
Chronic Pain
Dexmedetomidine Infusion Impact on Chronic Pain Patients
Chronic pain (CP) was defined as pain experienced daily or on most days and induced restriction of at least one activity. CP is one of the commonest complaints confronted in outpatient clinics and constitutes a challenge for all…
- Trial name
- NCT06402019
- Testing
- Dexmedetomidine in 0.9 % NaCl 20 Mcg/5 mL (4 Mcg/mL) INTRAVEN SYRINGE (ML), normal saline
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Hypotensive Anesthesia, Ear, Nose and Throat Procedure
Labetalol Infusion and Dexmedetomidine Infusion in Hypotensive Anesthesia
this study aims to compare between the role of Labetalol infusion versus Dexmedetomidine infusion in hypotensive anesthesia in Ear, Nose and Throat surgeries.
- Trial name
- NCT06752863
- Testing
- Hypotensive anesthesia in ear, nose and throat surgeries using labetalol and dexmedetomidine infusions
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Abdominal Surgery Patients
Bariatric Dose-ranging Study With Dexmedetomidine
After obtaining informed consent,80 morbidly obese ASA II-III patients undergoing laparoscopic bariatric surgery procedures would be randomly assigned to one of four study groups at UTSWMC at Dallas.Hemodynamic paarameters…
- Trial name
- NCT00363935
- Testing
- Dexmedetomidine
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Rhinosinusitis
Dexmedetomidine Infusion in Either Total Intravenous Anesthesia or Inhalational Anesthesia to Improve Surgical Field Visibility in Endoscopic Sinus Surgery
Dexmedetomidine Infusion in either Total Intravenous Anesthesia or Inhalational Anesthesia to Improve Surgical Field Visibility in Endoscopic Sinus Surgery
- Trial name
- NCT06866145
- Testing
- functional endoscopic sinus surgery, Dexmedetomidine
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Menoufia University
Dexmedetomidine, Ketofol
Dexmedetomidine vs Ketofol on Delirium in Children Undergoing Congenital Inguinal Hernia Repair
The aim of this study is to compare the effect of dexmedetomidine versus ketofol on the incidence of the emergence delirium in children undergoing congenital inguinal hernia repair.
- Conditions
- Dexmedetomidine, Ketofol, Delirium, Hernia
- Trial name
- NCT05786833
- Testing
- Dexmedetomedine, Ketofol, isotonic saline 0.9%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Regional Cerebral Tissue Oxygen Saturation
Effect of Dexmedetomidine and Propofol on Regional Cerebral Tissue Oxygen Saturation
50 patients divided into 2 groups .Group I Dexmedetomidine infusion. Group II with Propofol infusion
- Trial name
- NCT03817112
- Testing
- Dexmedetomidine Hydrochloride 0.1 MG/ML, Propofol 10 MG/ML
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Analgesia
Opioid Sparing Analgesia: Dexmedetomidine Versus Lidocaine for Intracranial Surgeries in Children
Perioperative pain control is necessary in children as inadequate treatment may lead to progression of perception of pain and development of chronic pain in the future.
- Trial name
- NCT04535089
- Testing
- Dexmedetomidine injection, Lidocaine Iv
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Delirium, Cognitive Decline
Dexmedetomidine or Clonidine Infusion for Prevention of Delirium After Open Heart Surgery
A parallel-group treatment, five-centre, participant and investigator masked, three-arm study to assess the safety and effectiveness of dexmedetomidine or clonidine infusion compared to placebo for the prevention of delirium and…
- Conditions
- Delirium, Cognitive Decline, Frailty
- Trial name
- ALPHA2PREVENT (NCT05029050)
- Testing
- Dexmedetomidine, Clonidine, Natriumchlorid
- Where
- 5 sites in Norway
- Volunteers
- 900 people
- Sponsor
- Oslo University Hospital
Post Operative Sore Throat
A Postoperative Sore Throat After Lumbar Spine Surgery in the Prone Position
This study was performed to compare the effect of dexmedetomidine and remifentanil on the incidence and severity of postoperative sore throat in patients undergoing spinal surgery in the prone position who are at risk of…
- Trial name
- NCT05345574
- Testing
- dexmedetomidine infusion, remifentanil infusion
- Where
- South Korea
- Volunteers
- 104 people
- Sponsor
- Yeungnam University College of Medicine
Pharmacokinetics, Sedation
Pharmacokinetics of Dexmedetomidine During Prolonged Infusion in ICU
The study will examine dexmedetomidine levels in the blood of critically ill intensive care patients to understand how it is broken down by the body.
- Trial name
- DEX PK (NCT00747721)
- Testing
- Dexmedetomidine
- Where
- Finland
- Volunteers
- 13 people
- Sponsor
- Orion Corporation, Orion Pharma
Obesity; Drug
Evaluation of the Effect of Different Doses Dexmedetomidine Infusion on Lung Mechanics and Oxygenation in Obese Patients
The objective of this study is to evaluate the effect of different doses of dexmedetomidine infusion intraoperative on lung mechanics and oxygenation regarding PaO2/Fraction of inspired oxygen), Intraoperative oxygenation, lung…
- Trial name
- NCT04730375
- Testing
- Dexmedetomidine Injection [Precedex]
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- National Cancer Institute, Egypt
Dexmedetomidine, Melatonin
Dexmedetomidine Infusion Versus Oral Melatonin for Prevention of Intensive Care Delirium
This study aims to compare the effect of dexmedetomidine infusion and oral melatonin on preventing delirium in intensive care unit (ICU) patients.
- Conditions
- Dexmedetomidine, Melatonin, Delirium
- Trial name
- NCT06076668
- Testing
- Dexmedetomidine, Melatonin 3 MG, Saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Anesthesia
The Efficacy of Adding Dexmedetomidine Perineurally to Bupivacaine in Ultrasound Guided Fascia Iliaca Block Versus Intravenously Infused Dexmedetomidine on Hemodynamic Stability Intraoperatively and Postoperative Analgesia Following Hip Arthroscopy
The current study aims to assess effectiveness of dexmedetomidine as adjuvant to general anesthesia on the hemodynamic stability and narcotic consumption intraoperatively and its effect as adjuvant to fascia iliaca compartment…
- Trial name
- NCT04917029
- Testing
- Bupivacaine hydrochloride perineurally, Dexmedetmidine infusion, Dexmedetomidine perineurally
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Ain Shams University
Tethered Cord
Effects of Anesthetic Infusion on the Amplitude of Motor Evoked Potential in Pediatrics Undergoing Tethered Spinal Cord Surgeries
The tethered spinal cord is a common pathology in pediatric neurosurgery. Intraoperative neurophysiologic monitoring (IOM) has gained popularity over the past two decades as a clinical discipline that uses neurophysiologic…
- Trial name
- NCT05591001
- Testing
- ketamine and dexmeditomidine combination, Propofol
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Cairo University
Morbid Obesity, Surgery
Ketamine Infusion vs Dexmedetomidine Infusion in Obese Patients Undergoing Bariatric Surgery
The surgeries that involve treatment of morbid obesity, i.e. bypass procedure and sleeve gastrectomy, are collectively covered under the term 'bariatric surgery'.
- Trial name
- NCT04576975
- Testing
- Ketamine, Dexmedetomidine, Normal Saline 0.9%
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Otosclerosis
Dexmedetomidine vs. Remifentanil Conscious Sedation for Stapedotomy/Stapedectomy
Dexmedetomidine continuous intravenous infusion vs. remifentanil target-controlled infusion conscious sedation for stapedotomy/stapedectomy- a prospective, single-center, double-masked randomized trial The goal of this clinical…
- Trial name
- NCT06283836
- Testing
- Dexmedetomidine, Remifentanil
- Where
- Romania
- Volunteers
- 74 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Pain Intractable, Delirium
Pilot Study Comparing Treatment With Dexmedetomidine to Midazolam for Symptom Control in Advanced Cancer Patients
Cancer patients with very difficult to control symptoms at the Abbotsford (AC) and Fraser Valley (FVC) Cancer Centers are referred and admitted to the Tertiary Palliative Care Units at the Abbotsford Regional Hospital and Cancer…
- Conditions
- Pain Intractable, Delirium, Dyspnea, Nausea
- Trial name
- NCT01687751
- Testing
- Dexmedetomidine, Midazolam
- Where
- Canada
- Sponsor
- Fraser Health
Dexmedetomidine Plus Esketamine Affect Postoperative Sleep Quality
The Effect of Dexmedetomidine and Esketamine Combined Infusion Quality of Sleep Undergoing Modified Radical Mastectomy
BACKGROUND: Some studies have revealed that intravenous dexmedetomidine and esketamine improve the quality of sleep after surgery.
- Trial name
- NCT06414941
- Testing
- Dexmedetomidine administration, Dexmedetomidine plus low-dose esketamine administration, Dexmedetomidine plus high-dose esketamine administration
- Where
- China
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Anqing Municipal Hospital
Post Operative Delerium
The Effect of Dexmedetomidine Infusion Alone Versus the Combination of Dexmedetomidine and Melatonin on Reduction of Post-operative Delirium (POD) After Open Brain Surgeries
The aim of this study is to illuminate the effect of combination of dexmedetomidine and oral melatonin versus the use of dexmedetomidine infusion alone on the improving of post-operative delirium (POD) on patients undergoing open…
- Trial name
- NCT07475156
- Testing
- Dexmedetomidine (DEX), Melatonin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Paroxysmal Sympathetic Hyperactivity
Stellate Ganglion Block Combined With Dexmedetomidine or Subanesthetic Ketamine Infusion for Treatment of Neurostorm.
Neurostorming is a sudden and exaggerated stress response as a result of damage to the brain. With appropriate treatment and time, there is hope for individuals to overcome storming, regain consciousness, and work towards…
- Trial name
- NCT06354673
- Testing
- Stellate ganglion block, Dexmedetomidine, Ketamine
- Where
- Egypt
- Volunteers
- 205 people
- Sponsor
- Zagazig University