Clinical trials: Dextrose Concentration
Diabetes Mellitus, Type 2
A Trial to Compare Blood Concentration Levels of Semaglutide Following Subcutaneous Injections of Semaglutide 1 mg by 2 Different Devices (the DV3372 Device and by the PDS290 Semaglutide Pen-injector)
This study compares semaglutide in two different injection tools called "PDS290" and "DV3372". The study aims to show similar levels of semaglutide in the blood when using either of the two injection tools.
- Trial name
- NCT03611322
- Testing
- Semaglutide, 0.25 mg, Semaglutide, 0.5 mg, Semaglutide, 1.0 mg
- Where
- Germany
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus Type 2, Vitamin D Deficiency
Vitamin D Supplementation in Patients With Diabetes Mellitus Type 2
Background and Objectives : The presence of vitamin D deficiency in patients with type 2 diabetes mellitus (T2DM) is associated with an increased risk of cardiovascular disease (CVD).
- Trial name
- DIMENSION (NCT01741181)
- Testing
- Vitamin D supplementation
- Where
- Singapore
- Volunteers
- 64 people
- Sponsor
- Tan Tock Seng Hospital
Regulation, Appetite, Eating Behavior
Impact of Different Breakfast Meals on Food Choices, Eating Behaviors and Brain Activation
This project aims to demonstrate that the best breakfast meal is the one able to improve the best postprandial hunger, satiety and adiposity regulators profile as well as the best reward-related gratification, due to hedonistic…
- Conditions
- Regulation, Appetite, Eating Behavior, Cognition
- Trial name
- NCT02516956
- Testing
- Breakfast consumption, Blood tests, Food choices and energy intakes assessments
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Parma
Subjects Without Diabetes Mellitus, Assessment of Glucose Concentrations
Assessment of Glucose Concentrations in People Without Diabetes Mellitus After Standardized Meals and in Daily Life
Participants will perform blood glucose monitoring (BGM) over the course of 14 days and, in parallel, wear continuous glucose monitoring (CGM) systems.
- Trial name
- NCT03405415
- Testing
- Blood glucose monitoring system and continuous interstitial glucose monitoring system
- Where
- Germany
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Institut für Diabetes-Technologie Forschungs- und Entwicklungsgesellschaft mbH an der Universität Ulm
Oxidative Stress
Vitamin E or Lipoic Acid on Serum Oxyphytosterol Concentrations
Background of the study: We now know that plant sterols can oxidize, which results in the formation of oxyphytosterols. Animal studies have suggested that oxyphytosterols are atherogenic components, however this relation has not…
- Trial name
- NCT01984567
- Testing
- Vitamin E, Lipoic acid, Control
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Maastricht University Medical Center
Type 2 Diabetes Mellitus
YKL-40 and Complications in Type 2 Diabetes
In this study, the investigators plan to establish the relationship between plasma concentration of YKL-40 with various vascular complications in the patients of type 2 diabetes.
- Trial name
- NCT01387984
- Where
- Taiwan
- Volunteers
- 473 people
- Sponsor
- National Taiwan University Hospital
Growth Hormone Deficiency, Cardiovascular Diseases
GH and Cardiovascular Risk Factors
Rationale: Abnormally low and high levels of insulin-like growth factor-I (IGF-I) are both associated with increased metabolic risk.
- Conditions
- Growth Hormone Deficiency, Cardiovascular Diseases, Metabolic Syndrome, Cognition
- Trial name
- NCT01877512
- Testing
- Change in daily dosage of Growth Hormone
- Where
- Netherlands
- Volunteers
- 32 people
- Sponsor
- Amsterdam UMC, location VUmc
Type2 Diabetes
Effect of Neprilysin on Glucagon-Like Peptide-1 in Patients With Type 2 Diabetes
Glucagon-like peptide-1(GLP-1) is secreted during a meal and increases glucose induced insulin secretion. The enzyme dipeptidyl peptidase 4(DPP-4) cleaves intact GLP-1 within minutes and DPP-4 inhibitors are therefore used for…
- Trial name
- NEPT2D (NCT03893526)
- Testing
- Entresto, Sitagliptin, Valsartan
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Copenhagen
Type 2 Diabetes Mellitus
Study of Saxagliptin, 5-Hydroxy Saxagliptin, and Metformin Concentrations/Levels in Pediatric Subjects With T2DM
The purpose of this study is to evaluate the pharmacokinetics of Saxagliptin, 5-hydroxy Saxagliptin, and Metformin in pediatric subjects with Type 2 diabetes mellitus (T2DM) following oral administration of Saxagliptin and…
- Trial name
- NCT01525225
- Testing
- Metformin immediate release (IR), Saxagliptin, Metformin IR
- Where
- 7 sites in United States
- Volunteers
- 4 people
- Sponsor
- AstraZeneca
Glucose Intolerance, Inflammation
Metformin & Inflammation in Pre-diabetic Children
Hypothesis. To determine the effect of metformin on the concentrations of resistin and other insulin resistance or inflammatory markers (C-reactive protein, cytokines, body weight, HbA1c, among others) in minors with glucose…
- Conditions
- Glucose Intolerance, Inflammation, Diabetes
- Trial name
- NCT01394887
- Testing
- Metformin
- Where
- Mexico
- Volunteers
- 52 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico